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Targets Recommended: Proton pump Phospholipase Antibacterial Autophagy

2

抑制剂 & 化合物

5

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T0757 Omeprazole

Losec,Prilosec,奥美拉唑,奥美拉挫,H 16868,Antra

Proton pump; Phospholipase; Antibacterial; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
Omeprazole (Losec) 是一种质子泵抑制剂,有研究胃肠道疾病的潜力。它竞争性抑制 CYP2C19活性,Ki 为 2 到 6 μM。它还抑制革兰氏阳性菌和革兰氏阴性菌生长。它是中性鞘磷脂酶的外泌体抑制剂。
T22391 Omeprazole Sodium

P450; Proton pump; Antibacterial; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
Omeprazole 是有效的质子泵抑制剂,在胃肠道疾病的研究中具有价值。它竞争性抑制CYP2C19活性,Ki 为 2 到 6 μM。它还抑制革兰氏阴性菌和革兰氏阳性菌生长。它是中性鞘磷脂酶的外泌体抑制剂。

化合物

Omeprazole
Cat.No: T0757
Synonym: Losec,Prilosec,奥美拉唑,奥美拉挫,H 16868,Antra
Target: Proton pump, Phospholipase, Antibacterial, Autophagy
Omeprazole Sodium
Cat.No: T22391
Synonym:
Target: P450, Proton pump, Antibacterial, Autophagy
Cat. No. Product Name Species Expression System
TMPK-01413 H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)

H-2K,OVA,MHC,H2-K1

Mouse HEK293 Cells
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se...
TMPK-01534 Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)

RING12,PSMB9,Proteasome chain 7,RMF,LMP-2,LMP2,M

Human & Mouse HEK293 Cells
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01523 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)

WAGR,WT33,AWT1,GUD,RMF,WT1,WIT-2,MHC,NPHS4...

Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPK-01535 Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)

Macropain chain 7,LMP2,Proteasome chain 7,...

Human & Mouse HEK293 Cells
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01522 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)

RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,WT1,NPHS4...

Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.

重组蛋白

H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)
Cat.No: TMPK-01413
Species: Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01534
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01523
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01535
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01522
Species: Human & Mouse
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
T12308 Omeprazole-d3

奥美拉挫 D3,H 16868 D3

Others Others
Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)

同位素标记化合物

Omeprazole-d3
Cat.No: T12308
Synonym: 奥美拉挫 D3,H 16868 D3
Target: Others
TargetMol Loading
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