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信号通路 血管生成 凋亡 自噬 细胞周期 表观遗传 细胞骨架
DNA损伤和修复 内分泌与激素 G蛋白偶联受体 免疫与炎症 JAK/STAT信号通路 MAPK信号通路 离子通道
代谢 微生物学 神经科学 NF-κB信号通路 氧化还原 PI3K/Akt/mTOR信号通路 蛋白酶体
干细胞 蛋白酪氨酸激酶 泛素化 PROTAC 其他
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类药性化合物库 多样性核心库Part2 多样性核心库Part1 药物靶点库 多样性核心预制库 Golden骨架库 Mini骨架库 化合物库深度定制
TargetMol Compound Library
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植物来源 列当科 水龙骨科 南洋杉科 报春花科 海金沙科 商陆科 买麻藤科
萝藦科 肉豆蔻科 鸭跖草科 交让木科 三白草科 海桐花科 五味子科 红厚壳科
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计算机辅助药物设计 虚拟筛选 分子对接 反向找靶 分子动力学模拟
基于靶点筛选实体化合物活性筛选 分子结合&互作检测 酶学靶点活性检测 核受体靶点活性检测 GPCR靶点活性检测
基于表型筛选实体化合物活性筛选 细胞增殖检测 细胞周期检测 细胞凋亡检测 药代动力学研究
药物设计和结构优化 化合物定制合成 分子砌块 网络药理学平台 软件平台
细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体
CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白
CAR-T 细胞治疗靶点蛋白 •   血液恶性肿瘤靶点蛋白 •   实体瘤靶点蛋白 酶 •   氧化还原酶 •   转移酶
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搜索结果

Search Results for " h 2003 "
Targets Recommended: Others

10

抑制剂 & 化合物

1

天然产物

16

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T24127 H2-003

H2003

 Others Others
H2-003 is a selective inhibitor of diacylglycerol acyltransferase 2 (DGAT2).
T37209 5-hydroxy Flunixin

Others Others
5-hydroxy Flunixin is a metabolite of the COX inhibitor flunixin .1 1.Daeseleire, E., Mortier, L., De Ruyck, H., et al.Determination of flunixin and ketoprofen in milk by liquid chromatography-tandem mass spectrometryAnal. Chim. Acta488(1)25-34(2003)
T37288 Remisporine B

Others Others
Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 30.1 and 32.4 μg/ml, respectively).1 1.Liu, H., Chen, S., Liu, W., et al.Polyketides with immunosuppressive activities from mangrove endophytic fungus Penicillium sp. ZJ-SY2Mar. Drugs14(12)217(2016) 2.Kong, F., and Carter, G.T.Remisporine B, a novel dimeric chrom...
T35582 H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)

Others Others
H-Arg-Gly-Asp-Cys-OH is a tetrapeptide that contains the arginine-glycine-aspartate (RGD) motif, a sequence that acts as a recognition site for various adhesion proteins.1It inhibits the binding of fibrinogen to endothelial cells and ADP-stimulated platelets with IC50values of 320 and 35 μM, respectively.2Implantation of titanium rods coated with H-Arg-Gly-Asp-Cys-OH increases bone formation in rat femurs.3H-Arg-Gly-Asp-Cys-OH has been conjugated to polyethylenimine to improve gene transfection ...
T35549 Elsinochrome A

Others Others
Elsinochrome A is a perylenequinone fungal metabolite that has been found inHypomycesand has anticancer activity.1Photoactivation of elsinochrome A induces the production of singlet oxygen and apoptosis in R366.4 rhesus monkey embryonic stem cells and HCe-8693 colorectal carcinoma cells when used at concentrations ranging from 1 to 100 μM. 1.Ma, L., Tai, H., Li, C., et al.Photodynamic inhibitory effects of three perylenequinones on human colorectal carcinoma cell line and primate embryonic stem ...
T35993 Epitalon (acetate)

Others Others
Epitalon is a synthetic tetrapeptide with anti-aging properties.1,2,3,4 Dietary administration of epitalon (0.00001% w/w) reduces levels of lipid peroxidation products in aged D. melanogaster tissue homogenates.1 Epitalon (1 μg/animal) delays age-related estrous shutdown and decreases the frequency of bone marrow cell chromosomal aberrations in female mice.2 It decreases spontaneous mammary gland and ovarian tumor development and metastasis in aged female mice.3 Epitalon also stimulates melatoni...
T38286 C26 Sphingomyelin (d18:1/26:0)

C26 Sphingomyelin (d18:1/26:0)

 Others Others
C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory condition characterized by excessive immune activation.3C26 sphingomyelin has been used a component of monolayers to study the influence of sphingomyelin acyl chain length on sphingomyelin-sterol interactions.4[Matreya, LLC.] 1.Wang, J.-R., Zhang, H., Yau, L.D., et al.Improved sphi...
T36881 NHC-diphosphate triammonium

Others Others
NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA[1][2]. In an intracellular metabolism assay, HCV replicon cells are treated with 10 μM 3H-labeled NHC, and intracellular nucleotide levels are determined after 1, 2 and 8 hours incubations. NHC is rapidly convered into the mono...
T37736 N-cis-hexadec-9Z-enoyl-L-Homoserine lactone

N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone

 Others Others
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of whic...
T37741 N-hexadecanoyl-L-Homoserine lactone

C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone

 Others Others
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which...

化合物

H2-003
Cat.No: T24127
Synonym: H2003
Target: Others
5-hydroxy Flunixin
Cat.No: T37209
Synonym:
Target: Others
Remisporine B
Cat.No: T37288
Synonym:
Target: Others
H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)
Cat.No: T35582
Synonym:
Target: Others
Elsinochrome A
Cat.No: T35549
Synonym:
Target: Others
Epitalon (acetate)
Cat.No: T35993
Synonym:
Target: Others
C26 Sphingomyelin (d18:1/26:0)
Cat.No: T38286
Synonym: C26 Sphingomyelin (d18:1/26:0)
Target: Others
NHC-diphosphate triammonium
Cat.No: T36881
Synonym:
Target: Others
N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
Cat.No: T37736
Synonym: N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
Target: Others
N-hexadecanoyl-L-Homoserine lactone
Cat.No: T37741
Synonym: C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone
Target: Others
Cat. No. Product Name Target Signaling Pathways
T36000 3-Hydroxyterphenyllin

Others Others
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi...

天然产物

3-Hydroxyterphenyllin
Cat.No: T36000
Synonym:
Target: Others
Species：
H7N7 (4)
Human & Mouse (4)
H5N1 (3)
H3N2 (2)
H9N5 (2)
Mouse (1)
Expression System：
HEK293 Cells (12)
Baculovirus Insect Cells (4)
Tag：
C-His (9)
C-His-Avi (5)
N-His (1)
Tag Free (1)
Cat. No. Product Name Species Expression System
TMPY-01242 Influenza A H7N7 (A/Netherlands/219/2003) Hemagglutinin/HA Protein (His)

Harvey rat sarcoma viral oncogene homolog

 H7N7 Baculovirus Insect Cells
Influenza A H7N7 (A/Netherlands/219/2003) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q6VMK1.
TMPY-01538 Influenza A H3N2 (A/Wyoming/03/2003) Hemagglutinin Protein (His)

Harvey rat sarcoma viral oncogene homolog

 H3N2 HEK293 Cells
Influenza A H3N2 (A/Wyoming/03/2003) Hemagglutinin Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is B2XWY0.
TMPY-00169 Influenza A H3N2 (A/Wyoming/03/2003) Hemagglutinin/HA Protein (His)

Harvey rat sarcoma viral oncogene homolog

 H3N2 Baculovirus Insect Cells
Influenza A H3N2 (A/Wyoming/03/2003) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.1 kDa and the accession number is B2XWY0.
TMPY-04533 Influenza A H7N7 (A/Netherlands/219/2003) Neuraminidase/NA Protein

Neuraminidase,NA Protein

 H7N7 HEK293 Cells
Influenza A H7N7 (A/Netherlands/219/2003) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 51.8kDa and the accession number is Q6VGI7.
TMPY-00174 Influenza A H9N5 (A/shorebird/DE/261/2003) Hemagglutinin/HA Protein (His)

Harvey rat sarcoma viral oncogene homolog

 H9N5 Baculovirus Insect Cells
Influenza A H9N5 (A/shorebird/DE/261/2003) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.3 kDa and the accession number is Q20NF5.
TMPY-00373 Influenza A H7N7 (A/Netherlands/219/2003) Neuraminidase/NA Protein (His)

Neuraminidase,NA Protein

 H7N7 HEK293 Cells
Influenza A H7N7 (A/Netherlands/219/2003) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa and the accession number is Q6VGI7.
TMPY-01260 Influenza A H7N7 (A/Netherlands/219/2003) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

 H7N7 HEK293 Cells
Influenza A H7N7 (A/Netherlands/219/2003) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q6VMK1.
TMPY-00104 Influenza A H9N5 (A/shorebird/DE/261/2003) Hemagglutinin /HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

 H9N5 HEK293 Cells
Influenza A H9N5 (A/shorebird/DE/261/2003) Hemagglutinin /HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q20NF5.
TMPY-01535 Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA1 Protein (S28W, His)

Harvey rat sarcoma viral oncogene homolog

 H5N1 HEK293 Cells
Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA1 Protein (S28W, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q4H2E2.
TMPY-04292 Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA Protein (S28W, RRRKKR to TETR, His)

Harvey rat sarcoma viral oncogene homolog

 H5N1 Baculovirus Insect Cells
Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA Protein (S28W, RRRKKR to TETR, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.9 kDa and the accession number is Q4H2E2.
TMPY-01702 Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA Protein (S28W, RRRKKR to TETR, uncleaved, His)

Harvey rat sarcoma viral oncogene homolog

 H5N1 HEK293 Cells
Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA Protein (S28W, RRRKKR to TETR, uncleaved, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is Q4H2E2.
TMPK-01413 H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)

H-2K,OVA,MHC,H2-K1

 Mouse HEK293 Cells
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se...
TMPK-01534 Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)

RING12,PSMB9,Proteasome chain 7,RMF,LMP-2,LMP2,M

Human & Mouse HEK293 Cells
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01523 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)

WAGR,WT33,AWT1,GUD,RMF,WT1,WIT-2,MHC,NPHS4...

 Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPK-01535 Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)

Macropain chain 7,LMP2,Proteasome chain 7,...

 Human & Mouse HEK293 Cells
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01522 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)

RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,WT1,NPHS4...

 Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.

重组蛋白

Influenza A H7N7 (A/Netherlands/219/2003) Hemagglutinin/HA Protein (His)
Cat.No: TMPY-01242
Species: H7N7
Expression System: Baculovirus Insect Cells
Influenza A H3N2 (A/Wyoming/03/2003) Hemagglutinin Protein (His)
Cat.No: TMPY-01538
Species: H3N2
Expression System: HEK293 Cells
Influenza A H3N2 (A/Wyoming/03/2003) Hemagglutinin/HA Protein (His)
Cat.No: TMPY-00169
Species: H3N2
Expression System: Baculovirus Insect Cells
Influenza A H7N7 (A/Netherlands/219/2003) Neuraminidase/NA Protein
Cat.No: TMPY-04533
Species: H7N7
Expression System: HEK293 Cells
Influenza A H9N5 (A/shorebird/DE/261/2003) Hemagglutinin/HA Protein (His)
Cat.No: TMPY-00174
Species: H9N5
Expression System: Baculovirus Insect Cells
Influenza A H7N7 (A/Netherlands/219/2003) Neuraminidase/NA Protein (His)
Cat.No: TMPY-00373
Species: H7N7
Expression System: HEK293 Cells
Influenza A H7N7 (A/Netherlands/219/2003) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-01260
Species: H7N7
Expression System: HEK293 Cells
Influenza A H9N5 (A/shorebird/DE/261/2003) Hemagglutinin /HA1 Protein (His)
Cat.No: TMPY-00104
Species: H9N5
Expression System: HEK293 Cells
Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA1 Protein (S28W, His)
Cat.No: TMPY-01535
Species: H5N1
Expression System: HEK293 Cells
Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA Protein (S28W, RRRKKR to TETR, His)
Cat.No: TMPY-04292
Species: H5N1
Expression System: Baculovirus Insect Cells
Influenza A H5N1 (A/Hong kong/213/2003) Hemagglutinin/HA Protein (S28W, RRRKKR to TETR, uncleaved, His)
Cat.No: TMPY-01702
Species: H5N1
Expression System: HEK293 Cells
H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)
Cat.No: TMPK-01413
Species: Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01534
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01523
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01535
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01522
Species: Human & Mouse
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
T35698 Octanoic Acid-13C

Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d...

同位素标记化合物

Octanoic Acid-13C
Cat.No: T35698
Synonym:
Target:
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