Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05159 |
Granzyme A/GZMA Protein, Human, Recombinant (His)
CTLA3,granzyme A (granzyme 1, cytotoxic T-lymphocyte-associa... |
Human | HEK293 Cells |
Granzyme A/GZMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.5 kDa and the accession number is P12544-1. | |||
TMPH-02687 |
Granzyme A/GZMA Protein, Mouse, Recombinant (His)
CTLA-3,Granzyme A,Autocrine thymic lymphoma granzyme-like se... |
Mouse | E. coli |
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA. Granz... |