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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP2236L |
Cortistatin-8 acetate
Cortistatin-8 acetate(485803-62-1 Free base) |
GHSR | GPCR/G Protein |
Cortistatin-8 acetate 是一种皮质抑素类似物,是一种GHS-R拮抗剂,对生长激素促分泌素受体有抑制作用。Cortistatin-8 acetate 是一种合成皮质抑素衍生的生长素释放肽受体配体,不会改变人类对酰化生长素释放肽或海沙瑞林的内分泌反应。 | |||
T7809L |
Ipamorelin 2 Pivalic acid
NNC-26-0161 |
Others | Others |
Ipamorelin 2 Pivalic acid (NNC-26-0161) 是一种生长激素释放肽,可诱导大鼠纵向骨生长。 | |||
T34281 |
Relamorelin
BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131 |
GHSR | GPCR/G Protein |
Relamorelin (RM-131)是一种具有选择性和有效性的生长素释放肽/生长激素促分泌素受体 (GHSR) 激动剂,是一种有效的生长素释放肽模拟物,对 GHS-1a 受体具有很高的亲和力。Relamorelin 是一种具有中枢渗透性的五肽,可增加生长激素水平,加速胃排空,具有研究恶病质的潜力。 | |||
TP1570 |
Cortistatin-14
|
Somatostatin | GPCR/G Protein |
Cortistatin-14 是一种与生长抑素-14结构相似的神经肽,具有抗惊厥和神经保护作用,通过激活 sst(2)、生长素释放肽和 GABA(A/B) 受体损害小鼠的识别记忆巩固,可用于研究脓毒症引发的认知障碍。 | |||
T3630 |
Relugolix
RVT-601,瑞卢戈利,TAK-385 |
GNRH Receptor | GPCR/G Protein |
Relugolix (RVT-601) 是口服有活性的非肽性促性腺激素释放激素的拮抗剂。同 TAK-013 相比,它对人和猴子的受体具有高亲和力和强拮抗活性,它们的 IC50值分别为0.33 nM 和0.32 nM。它可用于研究性激素依赖性疾病,如子宫肌瘤、子宫内膜异位症、前列腺癌等。 | |||
T76318 |
GHRF, porcine
|
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GHRF, porcine 是一种生长激素释放激素 (GHRH) 多肽 (porcine)。GHRF, porcine 与 GHRHR 受体结合并促进生长激素的释放。 | |||
T7809 |
Ipamorelin
伊帕瑞林,NNC-26-0161 |
Others | Others |
Ipamorelin (NNC-26-0161) 是一种生长激素释放肽,可诱导大鼠纵向骨生长。 | |||
T82322 |
GHRF, mouse
Mouse growth hormone-releasing factor |
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GHRF, mouse为含44个氨基酸的小鼠生长激素释放肽,能够促进生长激素的释放与合成。 | |||
T36377 |
Somatorelin (1-44) amide (human) (trifluoroacetate salt)
|
||
Somatorelin (1-44) amide is a synthetic peptide that corresponds to the full 44-amino acid sequence of growth hormone-releasing hormone (GHRH), a hormone that stimulates the production of growth hormone from the pituitary gland and is involved in the regulation of cell proliferation and differentiation.1,2Somatorelin induces growth hormone release similarly to GHRHin vitroandin vivo.1 | |||
T80191 |
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA
|
Endogenous Metabolite | Metabolism |
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA,GHRP-1的一种代谢产物,属于生长激素释放肽类。作为Ala-His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2的同义物,GHRP-1能够刺激GH(生长激素)的释放。在大鼠垂体静态单层细胞试验中,GHRP-1可提高GH释放率和[Ca2+]i水平,但对cAMP浓度无显著影响。 | |||
T78003 |
[D-p-Cl-Phe6,Leu17]-VIP TFA
|
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[D-p-Cl-Phe6,Leu17]-VIP TFA,为竞争性及选择性血管活性肠肽(VIP)受体拮抗剂,其IC50为125.8 nM。该化合物针对胰高血糖素、促胰液素和GRF受体均不表现活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02522 |
GHRL Protein, Mouse, Recombinant (His)
Motilin-related peptide,Growth hormone... |
Mouse | E. coli |
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.; Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility. GHRL Protein, Mouse, Recombinant (His) is expressed in E. coli expre... | |||
TMPK-01491 |
HLA-A*02:01&B2M&HBV (FLLTRILTI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
MHC,HBV,Hepatitis B virus |
Human | HEK293 Cells |
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity in the south-eastern part of Europe. Seven main HBV-D subgenotypes have been described until now (D1-D7). | |||
TMPK-01501 |
HLA-A*02:01&B2M&HBV (FLLTRILTI) Tetramer Protein, Human, MHC (His & Avi)
MHC,Hepatitis B virus,HBV |
Human | HEK293 Cells |
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity in the south-eastern part of Europe. Seven main HBV-D subgenotypes have been described until now (D1-D7). | |||
TMPK-01505 |
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi), Biotinylated
E7,MHC,HPV16 |
Human | HEK293 Cells |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody. | |||
TMPK-01492 |
HLA-A*02:01&B2M&HBV (FLLTRILTI) Monomer Protein, Human, MHC (His & Avi)
Hepatitis B virus,HBV,MHC |
Human | HEK293 Cells |
Hepatitis B virus (HBV), is the leading cause of liver diseases infecting an estimated 240 million persons worldwide. The HBV prevalence rates are variables between different countries, with an high level of endemicity in the south-eastern part of Europe. Seven main HBV-D subgenotypes have been described until now (D1-D7). | |||
TMPK-01504 |
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Tetramer Protein, Human, MHC (His & Avi)
MHC,HPV16,E7 |
Human | HEK293 Cells |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody. | |||
TMPK-01506 |
HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi)
HPV16,E7,MHC |
Human | HEK293 Cells |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIJ-0268 |
Relugolix-d6
|
||
Relugolix-d6 是 Relugolix 的氘代化合物。Relugolix 的 CAS 号为 737789-87-6。Relugolix 是口服有活性的非肽性促性腺激素释放激素的拮抗剂。同 TAK-013 相比,它对人和猴子的受体具有高亲和力和强拮抗活性,它们的IC50值分别为0.33 nM和0.32 nM。它可用于研究性激素依赖性疾病,如子宫肌瘤、子宫内膜异位症、前列腺癌等。 |