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Cat. No. Product Name Target Signaling Pathways
T36333 Z-IETD-AFC

Z-IETD-AFC 是 caspase-8 和颗粒酶 B 的荧光底物，可用于定量半胱天冬酶-8 或颗粒酶 B 的活性。
TP1128 Ac-IEPD-AFC

IEPD
Ac-IEPD-AFC (IEPD) is a substrate of Granzyme B.
T8677 3,4 Dichloroisocoumarin

Others; Serine Protease; Cysteine Protease Others; Proteases/Proteasome
3,4 Dichloroisocoumarin 是一种颗粒酶、组织蛋白酶 G 和中性粒细胞弹性蛋白酶抑制剂
T80745 Z-Ala-Ala-Asp-CMK

Z-AAD-CMK

 Caspase Apoptosis; Proteases/Proteasome
Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) 是选择性granzyme B 抑制剂。
T78586L Ac-IETD-CHO TFA

Ac-IETD-CHO TFA（191338-86-0 Free base )

 Apoptosis; Caspase Apoptosis; Proteases/Proteasome
Ac-IETD-CHO TFA 是一种 granzyme B 和 caspase-8 抑制剂，通过阻断 caspase3 前体裂解抑制 caspase8 活性。Ac-IETD-CHO TFA 抑制 Fas 介导的细胞凋亡(Apoptosis)。
T83181 Ac-IETD-AMC

Ac-IETD-AMC为乙酰基（Ac）修饰的荧光caspase-8/颗粒酶B底物，常用于检测caspase-8活性。
T78586 Ac-​IETD-​CHO

Apoptosis Apoptosis
Ac-IETD-CHO是一种针对granzyme B和caspase 8的有效可逆抑制剂，能够阻止Fas介导的(Apoptosis)、出血和肝衰竭，并且能够抑制细胞毒性T淋巴细胞引发的细胞死亡。

化合物

Z-IETD-AFC
Cat.No: T36333
Synonym:
Target:
Ac-IEPD-AFC
Cat.No: TP1128
Synonym: IEPD
Target:
3,4 Dichloroisocoumarin
Cat.No: T8677
Synonym:
Target: Others, Serine Protease, Cysteine Protease
Z-Ala-Ala-Asp-CMK
Cat.No: T80745
Synonym: Z-AAD-CMK
Target: Caspase
Ac-IETD-CHO TFA
Cat.No: T78586L
Synonym: Ac-IETD-CHO TFA（191338-86-0 Free base )
Target: Apoptosis, Caspase
Ac-IETD-AMC
Cat.No: T83181
Synonym:
Target:
Ac-​IETD-​CHO
Cat.No: T78586
Synonym:
Target: Apoptosis
Cat. No. Product Name Target Signaling Pathways
TC0036 Compound Lup-20(29)-en-3-yl acetate

IL Receptor; VEGFR; Others; TNF; COX Angiogenesis; Apoptosis; Immunology/Inflammation; Neuroscience; Others; Tyrosine Kinase/Adaptors
Lup-20(29)-en-3-yl acetate 是 Lupeol 的衍生物，通过下调 TNF-α、IL-1β、MCP-1、COX-2、VEGF 和颗粒酶 B 来抑制类风湿性关节炎的进展。

天然产物

Compound Lup-20(29)-en-3-yl acetate
Cat.No: TC0036
Synonym:
Target: IL Receptor, VEGFR, Others, TNF, COX
Species：
Human (143)
Mouse (6)
Human & Mouse (4)
Expression System：
HEK293 Cells (132)
E. coli (20)
Baculovirus Insect Cells (1)
Tag：
C-His-Avi (138)
C-His (5)
C-6xHis (4)
N-10xHis, C-Myc (2)
N-6xHis (2)
N-His (1)
N-His-Avi (1)
Cat. No. Product Name Species Expression System
TMPY-05159 Granzyme A/GZMA Protein, Human, Recombinant (His)

CTLA3,granzyme A (gr...

 Human HEK293 Cells
Granzyme A/GZMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.5 kDa and the accession number is P12544-1.
TMPH-02687 Granzyme A/GZMA Protein, Mouse, Recombinant (His)

CTLA-3,Granzyme A,A<...

 Mouse E. coli
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA. Granz...
TMPY-00817 Granzyme B/GZMB Protein, Human, Recombinant (His)

CGL1,CTLA1,CSP-B,CTSGL1,HLP,SECT,CSPB,gra

Human HEK293 Cells
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the target cells depending on another membrane-binding granule protein, perforin, results in the activation of effector caspases and mitochondrial depolarization through caspase-dependent and -independent pathways, and consequently induces rapid cell apoptosis. Over 3 substrates of G...
TMPY-06567 Granzyme K/GZMK Protein, Human, Recombinant (His)

granzyme K,TRYP2

 Human HEK293 Cells
Granzyme K/GZMK Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.56 kDa and the accession number is NP_002095.1.
TMPJ-00770 Granzyme B/GZMB Protein, Mouse, Recombinant (His)

Gzmb,Cytotoxic cell protease 1,Fragmentin-...

 Mouse HEK293 Cells
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
TMPJ-00832 Granzyme D/GZMD Protein, Mouse, Recombinant (His)

Granzyme D,Gzmd

 Mouse HEK293 Cells
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a ro...
TMPY-00818 Granzyme H/GZMH Protein, Human, Recombinant (His)

CTSGL2,CSP-C,CCP-X,granzyme H,CTLA

Human HEK293 Cells
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes (A-G and M) have been identified in the mouse, but only five are known in humans (A, B, H, M, and granzyme 3), and granzyme H appears to be specifically human. Human granzyme H is a neutral serine protease that is expressed predominantly in the lymphokine-activated killer (LAK)/...
TMPH-02688 Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc)

Cytotoxic cell protease 2,B10,Gzmc,Gra...

 Mouse E. coli
This enzyme is probably necessary for target cell lysis in cell-mediated immune responses. Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.6 kDa and the accession number is P08882.
TMPH-02689 Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)

Gzmk,Granzyme K

 Mouse E. coli
Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 33.9 kDa. Accession number: O35205
TMPH-01412 Granzyme B Protein, Human, Recombinant (E. coli, His)

Cytotoxic T-lymphocyte proteinase 2,Gra

Human E. coli
Granzyme B Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.0 kDa and the accession number is P10144.
TMPJ-01253 Serpin A3N Protein, Mouse, Recombinant (His)

Serpina3n,Serine protease inhibitor A<...

 Mouse HEK293 Cells
Serine protease inhibitor A3N(Serpin A3N) is a serine protease inhibitor that is structurally related to α1 antichymotrypsin encoded by the SERPINA3 gene. Serpin A3N is highly expressed in brain, testis, lung, thymus, and spleen. It is expressed with low levels in bone marrow, kidney and skeletal muscle. Serpin A3N secreted by Sertoli cells may regulate the activity of locally produced Granzyme B. Granzyme B inhibition by Serpin A3N may therefore regulate Granzyme Bmediated killing by cytotoxic ...
TMPY-02210 Serpin B9 Protein, Human, Recombinant (His)

CAP-3,PI-9,CAP3,PI9,serpin peptida

Human Baculovirus Insect Cells
SerpinB9, also known as Cytoplasmic antiproteinase 3, CAP-3, Peptidase inhibitor 9, SERPINB9 and PI-9, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. Serpin-B9 ( CAP-3 / PI-9 ) is the only known human intracellular inhibitor of granzyme B (GrB), the effector molecule in immunity against cytomegalovirus (CMV) and in renal allograft rejection. Serpin-B9 and SPI-6 expression in immune-privileged cells, APCs, and CTLs protect these cells against the actions of gran...
TMPJ-01256 Caspase-10 Protein, Human, Recombinant (His)

CASP10,FAS-Associated De...

 Human E. coli
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human ca...
TMPK-01419 Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,HLA-A*02:01,Peptide Ready

 Human HEK293 Cells
Peptide Ready HLA-A*03:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*03:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01426 Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi)

HLA-A*02:01,Peptide Ready,MHC

 Human HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01421 Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

HLA-A*02:01,MHC,Peptide Ready

 Human HEK293 Cells
HLA-A*02:01&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01420 Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi)

Peptide Ready,MHC,HLA-A*02:01

 Human HEK293 Cells
Peptide Ready HLA-A*03:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*03:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01410 Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi)

HLA-A,MHC,Peptide Ready

 Human HEK293 Cells
Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01422 Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi)

Peptide Ready,MHC,HLA-A*02:01

 Human HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01425 Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,HLA-A*02:01,Peptide Ready

 Human HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01415 APC-equivalent Peptide Ready HLA-A*02:01&B2M Tetramer Protein, Human, MHC (His)

Peptide Ready,HLA-A*02:01,MHC

 Human HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Tetramer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01409 Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

Peptide Ready,MHC,HLA-A

 Human HEK293 Cells
Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01510 HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi)

NS,NS3,KRAS2,RASK2,MHC,RALD,K-R

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01463 HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi)

C-K-RAS,KI-RAS,KRAS1,K-RA

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01429 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

MHC,K-Ras 2,NS,K-RAS4A,KRA

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01500 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi)

CTAG1,CT6.1,CTAG1B,LAGE2A

Human HEK293 Cells
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01473 HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

CT1.3,MAGE-3,MZ2-D,MZ2D,HLA-A2402...

 Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01518 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi)

MHC,NS,KRAS1,K-RAS2A,GTPa

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01527 HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)

NS,RALD,C-K-RAS,RASK2,K-RA

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01408 HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

RALD,KRAS1,KRAS2,K-RAS2B...

 Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01433 HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi)

GTPase Kras,NS3,K-Ras 2,K-RA<...

 Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01455 HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)

OIP4,PRAME,OIP-4,MAPE

 Human HEK293 Cells
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.
TMPK-01401 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

MHC,CFC2,K-Ras 2,RALD,K-RAS4A...

 Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01488 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)

K-RAS4A,MHC,GTPase Kras,...

 Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01442 HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

HLA-A,P53,TP53,LFS1,MHC,BCC7,TRP53,FLJ9294...

 Human HEK293 Cells
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
TMPK-01445 HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

CT1.1,MAGE1,MAGE-1,MAGE-A

Human HEK293 Cells
MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPK-01477 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

HPAFP,FETA,Alpha-1-fetop...

 Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01493 HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Tetramer Protein, Human, MHC (His & Avi)

MZ2-D,Melanoma-associate...

 Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01458 HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi)

K-Ras 2,GTPase Kras,KRAS...

 Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01539 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi), Biotinylated

CTAG1B,CT6.1,MY-ESO-1,LAGE2A,NY-E...

 Human HEK293 Cells
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01529 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi)

K-RAS4A,KRAS1,MHC,K-RAS2...

 Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01484 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

HPAFP,FETA,AFP,AFPD,...

 Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01449 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)

MHC,CT6.1,CTAG1,LAGE-2,MY-ESO-1,NY-ESO-1,E...

 Human E. coli
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01480 HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

IAP4,Survivin,API4,BIRC5,MHC,MHC I,EPR-1,s...

 Human HEK293 Cells
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target.
TMPK-01404 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

NS,KRAS,KRAS1,KRAS2,MHC,RA

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01519 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

MHC,FETA,AFP,Alpha-feto,...

 Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01470 HLA-A*02:01&B2M&MAGE-A4 or MAGE-A8 (KVLEHVVRV) Monomer Protein, Human, MHC (His & Avi)

MAGE-A4 or MAGE-A8,M...

 Human HEK293 Cells
MAGE-A4 and MAGE-A8 are type I membes of the melanoma associated antigen (MAGE) family. The MAGE family is a large, highly conserved group of proteins that share a common MAGE homology domain. Both MAGE-A4 and MAGE-A8 antigen-presenting peptides can be presented by HLA-A*02:01.
TMPK-01481 HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

svn 2B,svn-2B,Survivin-2B

 Human HEK293 Cells
Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.
TMPK-01494 HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi)

HLA-A,HLA-A*0101,HLA...

 Human HEK293 Cells
Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPK-01444 HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein, Human, MHC (His & Avi)

MZ2-E,MAGE1A,MAGE-1 anti...

 Human HEK293 Cells
MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
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重组蛋白

Granzyme A/GZMA Protein, Human, Recombinant (His)
Cat.No: TMPY-05159
Species: Human
Expression System: HEK293 Cells
Granzyme A/GZMA Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02687
Species: Mouse
Expression System: E. coli
Granzyme B/GZMB Protein, Human, Recombinant (His)
Cat.No: TMPY-00817
Species: Human
Expression System: HEK293 Cells
Granzyme K/GZMK Protein, Human, Recombinant (His)
Cat.No: TMPY-06567
Species: Human
Expression System: HEK293 Cells
Granzyme B/GZMB Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00770
Species: Mouse
Expression System: HEK293 Cells
Granzyme D/GZMD Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00832
Species: Mouse
Expression System: HEK293 Cells
Granzyme H/GZMH Protein, Human, Recombinant (His)
Cat.No: TMPY-00818
Species: Human
Expression System: HEK293 Cells
Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02688
Species: Mouse
Expression System: E. coli
Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02689
Species: Mouse
Expression System: E. coli
Granzyme B Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01412
Species: Human
Expression System: E. coli
Serpin A3N Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01253
Species: Mouse
Expression System: HEK293 Cells
Serpin B9 Protein, Human, Recombinant (His)
Cat.No: TMPY-02210
Species: Human
Expression System: Baculovirus Insect Cells
Caspase-10 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01256
Species: Human
Expression System: E. coli
Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01419
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01426
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01421
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01420
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01410
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01422
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01425
Species: Human
Expression System: HEK293 Cells
APC-equivalent Peptide Ready HLA-A*02:01&B2M Tetramer Protein, Human, MHC (His)
Cat.No: TMPK-01415
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01409
Species: Human
Expression System: HEK293 Cells
HLA-A*03:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01510
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01463
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
Cat.No: TMPK-01429
Species: Human
Expression System: E. coli
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01500
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01473
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01518
Species: Human
Expression System: HEK293 Cells
HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01527
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01408
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01433
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01455
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)
Cat.No: TMPK-01401
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01488
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
Cat.No: TMPK-01442
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01445
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01477
Species: Human
Expression System: HEK293 Cells
HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01493
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01458
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01539
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01529
Species: Human
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01484
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)
Cat.No: TMPK-01449
Species: Human
Expression System: E. coli
HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01480
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
Cat.No: TMPK-01404
Species: Human
Expression System: E. coli
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01519
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MAGE-A4 or MAGE-A8 (KVLEHVVRV) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01470
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01481
Species: Human
Expression System: HEK293 Cells
HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01494
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01444
Species: Human
Expression System: HEK293 Cells
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