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TMPH-01408
|
GOLM1 Protein, Human, Recombinant (GST)
GOLM1,Golgi membrane protein GP73,Golgi ph...
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Human
|
E. coli
|
|
GOLM1 Protein, Human, Recombinant (GST) is expressed in E. coli. |
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TMPH-01136
|
COG5 Protein, Human, Recombinant (His)
GTC90,GOLTC1,Component of oligomeric Golgi complex ...
|
Human
|
E. coli
|
|
COG5 Protein, Human, Recombinant (His) is expressed in E. coli. |
|
TMPJ-00677
|
TGOLN2 Protein, Human, Recombinant (His)
Trans-Golgi network protein TGN51,TGN38 homolog,TGN...
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Human
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HEK293 Cells
|
|
This protein may be involved in regulating membrane traffic to and from trans-Golgi network. Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells. |
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TMPY-02193
|
GOLPH2/GOLM1 Protein, Human, Recombinant (His)
HEL46,PSEC0257,GOLPH2,bA379P1.3,C9orf155,GP73,golgi...
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Human
|
HEK293 Cells
|
|
Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colon, prostate, trachea, and stomach. It is expressed at a lower level in testis, muscle, lymphoid tissues, white blood cells, and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at a low level in the normal liver. Expression significantl... |
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TMPH-01409
|
GOLPH3 Protein, Human, Recombinant (His)
Mitochondrial DNA absence factor,Coat protein GPP34,GOLPH3,<...
|
Human
|
E. coli
|
|
GOLPH3 Protein, Human, Recombinant (His) is expressed in E. coli. |
|
TMPH-01395
|
QPCTL Protein, Human, Recombinant (His & SUMO)
isoQC,Glutaminyl-peptide cyclotransferase-like protein,G...
|
Human
|
E. coli
|
|
Responsible for the biosynthesis of pyroglutamyl peptides. QPCTL Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.5 kDa and the accession number is Q9NXS2. |
|
TMPY-03986
|
PIST Protein, Human, Recombinant (His)
CAL,dJ94G16.2,golgi-associated PDZ and coiled-coil ...
|
Human
|
E. coli
|
|
GOPC, also known as PIST, interacts specifically with TC1 (a Rho-family small GTPase)] as a binding partner for Rhotekin. Rhotekin associates with PIST in vitro and both polarized and non-polarized MDCK (Madin-Darby canine kidney) cells. The C-terminal SPV (Ser-Pro-Val) motif of Rhotekin binds to the PDZ domain of PIST. The co-localization of PIST and Rhotekin at the Golgi apparatus can be detected in non-polarized fibroblast-like MDCK cells and AJs (adherens junctions) in the fully polarized ce... |
|
TMPH-02647
|
FAM20C Protein, Mouse, Recombinant (His & Myc)
Fam20c,Dentin matrix protein 4,Golgi-enriched fract...
|
Mouse
|
Baculovirus Insect Cells
|
|
FAM20C Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 60.4 kDa and the accession number is Q5MJS3. |
|
TMPH-01100
|
CLINT1 Protein, Human, Recombinant (His)
KIAA0171,Epsin-related protein,ENTH,CLINT1,Clint,EpsinR,EPN4...
|
Human
|
E. coli
|
|
Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly. CLINT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 72.3 kDa and the accession number is Q14677. |
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TMPH-00942
|
AP1B1 Protein, Human, Recombinant (His & Myc)
Clathrin assembly protein complex 1 beta large chain,Adaptor...
|
Human
|
E. coli
|
|
AP1B1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. |
|
TMPJ-00137
|
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
TRDL-1,TNF- and APOL-related leukocyte expressed ligand 2,Tu...
|
Human
|
HEK293 Cells
|
|
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily recept... |
|
TMPY-00490
|
RAB6A Protein, Human, Recombinant (His)
RAB6A, member RAS oncogene family,RAB6
|
Human
|
E. coli
|
|
Rab6 is one of the most conserved Rab GTPaes throughout evolution and the most abundant Rab protein associated with the Golgi complex. The two ubiquitous Rab isoforms, Rab6A and Rab6A', that are generated by alternative splicing of the RAB6A gene, regulate several transport steps at the Golgi level, including retrograde transport between endosomes and Golgi, anterograde transport between Golgi and the plasma membrane, and intra-Golgi and Golgi to endoplasmic reticulum transport. In MEF cells, mo... |
|
TMPH-02164
|
Syntaxin-11 Protein, Human, Recombinant (GST)
STX11,Syntaxin-11
|
Human
|
E. coli
|
|
SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. |
|
TMPY-03461
|
GABARAPL2 Protein, Human, Recombinant (His)
GATE16,ATG8,ATG8C,GEF-2,GATE-16,GEF2,GABA(A) receptor-associ...
|
Human
|
E. coli
|
|
GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and small intestine. GATE-16 is involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. |
|
TMPY-02419
|
LMAN2 Protein, Human, Recombinant (His)
C5orf8,GP36B,lectin, mannose binding 2,VIP36
|
Human
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E. coli
|
|
LMAN2 (Lectin, Mannose Binding 2, also known as VIP36) is a Protein Coding gene. This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus, and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking, and quality control. The L-type lectin LMAN2 appears to be specifically required for the accumulation of GPRC5B in the Golgi complex and restriction of GPRC5B transport al... |
|
TMPY-00610
|
RAB2 Protein, Mouse, Recombinant (His)
C80220,Rab2,RAB2A, member RAS oncogene family,9330148M11Rik
|
Mouse
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E. coli
|
|
RAB2A, a protein essential for ER-to-Golgi transport, is critical in promoting proteolytic activity and 3D invasiveness of breast cancer (BC) cell lines.RAB2A is amplified and elevated in human BC and is a powerful and independent predictor of disease recurrence in BC patients. Thus, RAB2A is a novel trafficking determinant essential for regulation of a mesenchymal invasive program of BC dissemination. At the cellular levels, RAB2A controls both canonical polarized Golgi-to-Plasma membrane traff... |
|
TMPY-02376
|
BNIP3L Protein, Human, Recombinant
BCL2/adenovirus E1B 19kDa interacting protein 3-like,NIX,BNI...
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Human
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E. coli
|
|
The deletion of BNIP3L results in retention of mitochondria during lens fiber cell remodeling, and that deletion of BNIP3L also results in the retention of endoplasmic reticulum and Golgi apparatus. BNIP3L localizes to the endoplasmic reticulum and Golgi apparatus of wild-type newborn mouse lenses and is contained within mitochondria, endoplasmic reticulum and Golgi apparatus isolated from adult mouse liver. As the cells become packed with keratin bundles, Bnip3L expression triggers mitophagy to... |
|
TMPH-01099
|
CLTCL1 Protein, Human, Recombinant (His)
CLH-22,CLTD,CLTCL,CLTCL1,CLH22,Clathrin heavy chain on chrom...
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Human
|
E. coli
|
|
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. CLTCL1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.8 kDa and the accession number is P53675. |
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TMPH-01535
|
INSIG2 Protein, Human, Recombinant (His & Myc)
Insulin-induced gene 2 protein,INSIG2
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Human
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E. coli
|
|
Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR. Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. Binds oxysterol, including 22-hydroxycholesterol, 24-hydroxycho... |
|
TMPH-01079
|
CLN5 Protein, Human, Recombinant (His)
CLN5,BMPS,Bis(monoacylglycero)phosphate synthase CLN5,S-depa...
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Human
|
E. coli
|
|
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane. CLN5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 43.5 kDa and ... |
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TMPH-03686
|
Variola virus (isolate Human/India/Ind3/1967) OPG154 Protein (His)
Protein OPG154,OPG154
|
VARV
|
HEK293 Cells
|
|
Structural protein involved in the envelopment of mature virion (MV) to form the wrapped virion (WV). The wrapping consists of the addition of Golgi membranes to the mature virion. Participates in mature virion (MV) movement within the infected cell. May play an indirect role in MV-cell fusion. Variola virus (isolate Human/India/Ind3/1967) OPG154 Protein (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 16.5 kDa and the accession number is P33816. |
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TMPH-01420
|
SAR1A Protein, Human, Recombinant (GST)
SAR1A,COPII-associated small GTPase,GTP-binding protein SAR1...
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Human
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E. coli
|
|
Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). SAR1A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 49.4 kDa and the accession number... |
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TMPY-03959
|
CHST11 Protein, Human, Recombinant (His)
carbohydrate (chondroitin 4) sulfotransferase 11,HSA269537,C...
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Human
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Baculovirus Insect Cells
|
|
CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12;14)(q23;q32), has been reported in a patient with ... |
|
TMPY-02768
|
Selenoprotein M Protein, Human, Recombinant (His)
SEPM
|
Human
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E. coli
|
|
Selenoprotein M is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine M is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is expressed in a variety of tissues, and the protein is localized to the perinuclear structures.... |
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TMPH-02846
|
BICD2 Protein, Mouse, Recombinant (GST)
Bicd2,Kiaa0699,Bic-D 2,Protein bicaudal D homolog 2
|
Mouse
|
E. coli
|
|
Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (... |
|
TMPH-03687
|
Variola virus (isolate Human/India/Ind3/1967) OPG154 Protein (E. coli, His)
Protein OPG154,OPG154
|
VARV
|
E. coli
|
|
Structural protein involved in the envelopment of mature virion (MV) to form the wrapped virion (WV). The wrapping consists of the addition of Golgi membranes to the mature virion. Participates in mature virion (MV) movement within the infected cell. May play an indirect role in MV-cell fusion. Variola virus (isolate Human/India/Ind3/1967) OPG154 Protein (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.6 kDa and the accession number ... |
|
TMPH-03416
|
Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO)
N,Nucleoprotein,Nucleocapsid protein
|
RVFV
|
E. coli
|
|
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles. Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.... |
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TMPY-03868
|
ARF5 Protein, Human, Recombinant (His)
ARF5,ADP ribosylation factor 5
|
Human
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E. coli
|
|
ARF5, also known as ADP-ribosylation factor 5, belongs to the small GTPase superfamily, Arf family. Members of this family stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF5 functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. ARF5 Is involved in protein trafficking. ARF5 may also modulate vesicle budding and uncoating within the Golgi apparatus. |
|
TMPJ-01388
|
STX8 Protein, Human, Recombinant
STX8,Syntaxin-8
|
Human
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E. coli
|
|
Syntaxin-8 is a single-pass type IV membrane protein which belongs to the syntaxin family. It contains one t-SNARE coil homology domain. STX8 is highly expressed in heart, also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. STX8 is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. It as a vesicle trafficking protein functions in the early secretory pathway, possibly mediating retrograde transport form cis-golgi m... |
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TMPH-03661
|
Vaccinia virus (strain Western Reserve) OPG154 Protein (His & Myc)
OPG154,Protein OPG154
|
VACV
|
E. coli
|
|
Structural protein involved in the envelopment of mature virion (MV) to form the wrapped virion (WV). The wrapping consists of the addition of Golgi membranes to the mature virion. Participates in mature virion (MV) movement within the infected cell. May play an indirect role in MV-cell fusion. Vaccinia virus (strain Western Reserve) OPG154 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.6 kDa and the accession numbe... |
|
TMPY-03796
|
ARF3 Protein, Human, Recombinant (His)
ADP-ribosylation factor 3
|
Human
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E. coli
|
|
ARF3, also known as ADP-ribosylation factor 3, belongs to the RAS superfamily. Members of this family include ARF1, ARF2, ARF3, ARF4, ARF5 and ARF6. ARF3 gene is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF3 functions as an allosteric activator of the cholera toxin subunit, an ADP-ribosyltrans... |
|
TMPJ-01398
|
ITM2B Protein, Human, Recombinant (His)
Transmembrane Protein BRI,Protein E25B,BRI2,imBRI2,Immature ...
|
Human
|
HEK293 Cells
|
|
Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervou... |
|
TMPJ-01200
|
IMPA3 Protein, Mouse, Recombinant (His)
Inositol monophosphatase 3,Impad1
|
Mouse
|
HEK293 Cells
|
|
IMPAD1 protein (IMPA3, gPAPP or IMPase 3) belongs to the inositol monophosphatase family. It is found in Purkinje cells, brain stem, lung and chondrocytes. Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded glycoprotein with 356 amino acid residues which generates a 306 amino acid residues mature protein after processing. It is expressed in embryo, and in theory may catalyze myo-inositol monophosphate to myo-inositol. Free myo-inositol is used to generate inositol phospholipid, an ... |
|
TMPJ-01013
|
VCP Protein, Human, Recombinant (His)
TER ATPase,Transitional Endoplasmic Reticulum ATPase,15S Mg(...
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Human
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E. coli
|
|
Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. It is necessary for the fragmentation of Golgi stacks during mitosis and their reassembly after mitosis. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin... |
|
TMPJ-01406
|
MOB4 Protein, Human, Recombinant (His)
PREI3,MOBKL3,Mps One Binder Kinase Activator-Like 3,Mob1 Hom...
|
Human
|
E. coli
|
|
MOB-Like Protein Phocein is a member of the MOB1/Phocein Family. MOB-Like Protein Phocein is associated with membranes and the Golgi stacks. It is present in the cytosol, where it behaves as a protein complex. It has been shown that MOB-Like Protein Phocein interacts with DNM1, EPS15 and Nucleoside Diphosphate Kinase. MOB-Like Protein Phocein is the major partner of Striatin Family members and may play a important role in membrane trafficking, specifically in membrane budding reactions. |
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TMPY-01818
|
TPST1 Protein, Human, Recombinant (His)
tyrosylprotein sulfotransferase 1,TANGO13A
|
Human
|
HEK293 Cells
|
|
Protein-tyrosine sulfotransferase 1, also known as Tyrosylprotein sulfotransferase 1 and TPST1, is a single-pass type II membrane protein that belongs to the protein sulfotransferase family. Tyrosine O-sulfation is a common posttranslational modification of proteins in all multicellular organisms. This reaction is mediated by a Golgi enzyme activity called tyrosylprotein sulfotransferase (TPST) that catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to tyrosine residues... |
|
TMPJ-00220
|
B3GAT1 Protein, Human, Recombinant (His)
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)...
|
Human
|
HEK293 Cells
|
|
B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. It adds a glucuronic residue to the terminal lactosamine residue (Gal beta 14GlcNAc) of a glycoprotein or glycolipid, which can be further sulfated to become the HNK1 epitope, a unique trisaccharide structure, HSO3-3GlcA beta 1-3Gal beta 1-4GlcNAc. The enzyme activity was found to be enhanced in the presence of sphingomyelin an... |
|
TMPJ-00670
|
YKT6 Protein, Human, Recombinant (His)
YKT6,Synaptobrevin homolog YKT6
|
Human
|
E. coli
|
|
Synaptobrevin Homolog YKT6 (YKT6) is an enzyme that belongs to the Synaptobrevin family. YKT6 contains a longin domain and a v-SNARE coiled-coil homology domain. YKT6 is highly conserved from yeast to human and it can functionally complement the loss of the yeast homolog in the yeast secretory pathway. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. YKT6 is considered as one of the SNARE recognition molecules implicated in vesi... |
|
TMPJ-01380
|
ST6GalNAc2 Protein, Human, Recombinant (His)
GalNAc α-2,SIATL1,SIAT7B,GalNAc Alpha-2,SIAT7-B,Sialyltransf...
|
Human
|
HEK293 Cells
|
|
Alpha-N-Acetylgalactosaminide α-2,6-Sialyltransferase 2 (ST6GALNAC2) belongs to the glycosyltransferase 29 family that adds sialic acids to the non-reducing ends of glycoconjugates. At the cell surface, these modifications play roles in cell-cell and cell-substrate interactions, bacterial adhesion and protein targeting. ST6GALNAC2 is localized to the Golgi apparatus membrane. ST6GALNAC2 is highly expressed in lactating mammary glands and the adult testis; it is expressed at lower levels in the k... |
|
TMPH-02648
|
PKDCC Protein, Mouse, Recombinant (His & Myc)
Extracellular tyrosine-protein kinase PKDCC,Vertebrate lones...
|
Mouse
|
Baculovirus Insect Cells
|
|
Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation. May be indirectly involved in protein transport from the Golgi apparatus to the plasma membr... |
|
TMPH-02873
|
RAB10 Protein, Mouse, Recombinant (His & SUMO)
Ras-related protein Rab-10,Rab10
|
Mouse
|
E. coli
|
|
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, f... |
|
TMPJ-01044
|
NCALD Protein, Human, Recombinant (His)
Neurocalcin-δ,Neurocalcin-Delta,NCALD
|
Human
|
E. coli
|
|
Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein possesses a Ca2+ /myristoyl switch. It is cytosolic at resting calcium levels. However, elevated intracellular calcium levels induce a conformational change which exposes the myristoyl group, resulting in protein association with membranes a... |
|
TMPY-03866
|
Syntaxin 3 Protein, Human, Recombinant (His)
syntaxin 3,STX3A
|
Human
|
E. coli
|
|
STX3, also known as syntaxin 3, belongs to the syntaxin family. STX3 is a target membrane protein (t-SNARE) that is needed for membrane fusion. Membrane fusion requires the formation of a complex between a vesicle protein (v-SNARE) and t-SNAREs. STX3, together with syntaxin 2, are predominantly localized at the plasma membrane. Syntaxin 2 cycles between the plasma membrane and the perinuclear compartment whereas syntaxin 3 cycles between the plasma membrane and the trans-Golgi network. It is pos... |
|
TMPY-03616
|
NAPG Protein, Human, Recombinant (His)
γSNAP,GAMMASNAP,N-ethylmaleimide-sensitive factor attachment...
|
Human
|
E. coli
|
|
NAPG (NSF Attachment Protein Gamma, also known as gamma SNAP) is a Protein Coding gene. This gene encodes soluble NSF attachment protein gamma. The encoded protein mediates platelet exocytosis and controls the membrane fusion events of this process. NAPG is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. NAPG belongs to the SNAP family. It is widely expressed in the brain, thyroid, and other tissues. SNAPs enable N-ethyl-maleimide-sensitive fusion prot... |
|
TMPY-06815
|
SYAP1 Protein, Human, Recombinant (His)
PRO3113,synapse associated protein 1
|
Human
|
Baculovirus Insect Cells
|
|
Synapse-associated protein 1 (SYAP1), also known as PRO3113 and BSTA, belongs to the synapse-associated BSD domain family, featuring three α-helices and two conserved tryptophan and phenylalanine residues located at the C-terminus. Expressed near neuronal Golgi and synaptic regions of cerebellar Purkinje cells, SYAP1 has been linked to intact sensorimotor control and general vesicular trafficking in neurons. SYAP1-deficient mice display impaired locomotor activity. In cultured adipocytes, SYAP1 ... |
|
TMPJ-00740
|
PTH Protein, Human, Recombinant
PTH,Parathyrin,Parathyroid Hormone,Parathormone
|
Human
|
E. coli
|
|
Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processi... |
|
TMPH-02301
|
VPS35 Protein, Human, Recombinant (His & Myc)
VPS35,Vacuolar protein sorting-associated protein 35,Vesicle...
|
Human
|
E. coli
|
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Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The CSC seems to associate with the cytoplasmic domain of cargo proteins predominantly via VPS35; however, these interactions seem to be of... |
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TMPJ-00456
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APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
TRDL-1,TNFSF13,CD256,TALL-2,A proliferation-inducing ligand
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Mouse
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HEK293 Cells
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Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissu... |
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TMPH-02666
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Fukutin Protein, Mouse, Recombinant (His & Myc)
Fktn,Fukutin,Ribitol-5-phosphate transferase FKTN,Fukuyama-t...
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Mouse
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E. coli
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Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-b... |
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TMPJ-00438
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SECTM1A Protein, Mouse, Recombinant (His)
Sectm1a
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Mouse
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HEK293 Cells
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SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts. Stimulation with IFN gamma is often necessary to detect h... |
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