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Search Results for " glp1r "

Targets Recommended: Glucagon Receptor

9

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T15387	GLP-1R Antagonist 1	Glucagon Receptor	GPCR/G Protein
	GLP-1R Antagonist 1 (compound 5d) 是口服有效的、能透过中枢神经系统的，胰高血糖素样肽 1 受体 (GLP-1R) 的非竞争性抑制，其 IC50 值为 650 nM。
T36579	GLP-1R Agonist DMB	Glucagon Receptor	GPCR/G Protein
	GLP-1R Agonist DMB 是胰高血糖素样肽1受体的激动剂（GLP-1R；重组人受体的 KB＝26.3nM）。
T40997	GLP-1R modulator C16 GLP-1R modulator C16	Glucagon Receptor	GPCR/G Protein
	GLP-1R modulator C16 是一种变构调节剂，显著增加了 GLP-4 的结合亲和力。
T40279	GLP-1R modulator L7-028 GLP-1R modulator L7-028	cAMP; Glucagon Receptor	GPCR/G Protein
	GLP-1R modulator L7-028 是一种变构调节剂，增强了对 GLP-1 的亲和力和 cAMP 信号转导。
T19850	Semaglutide 索玛鲁肽,司美格鲁肽,索马鲁肽	Glucagon Receptor	GPCR/G Protein
	Semaglutide 是人胰高血糖素样肽-1受体激动剂，是一种人胰高血糖素样肽-1 的长效类似物。它有用于 2 型糖尿病研究的潜力。
T80565	Gulgafafusp alfa
	Gulgafafusp alfa 为人源化IgG2κ类抗体，专一性靶向GLP1R（胰高血糖素样肽1受体）。
T76279	Retatrutide LY3437943	Glucagon Receptor	GPCR/G Protein
	Retatrutide (LY3437943) 是胰高血糖素受体、葡萄糖依赖性促胰岛素多肽受体和胰高血糖素样肽-1 受体三重激动剂,对GCGR、GIPR 和 GLP-1R 具有抑制作用。Retatrutide 可用研究肥胖症。
T76279L1	Retatrutide sodium salt Retatrutide sodium salt(2381089-83-2 free base),LY3437943 sodium salt	Glucagon Receptor	GPCR/G Protein
	Retatrutide sodium salt 是一种有效的胰高血糖素受体 (GCGR)、葡萄糖依赖性促胰岛素多肽受体 (GIPR) 和胰高血糖素样肽-1 受体 (GLP-1R) 的三重激动剂肽。Retatrutide sodium salt 可用于研究2型糖尿病和肥胖症。
T17242	VU0453379	Others	Others
	VU0453379 is a highly selective and central nervous system penetrant positive allosteric modulator of glucagon-like peptide-1R (EC50: 1.3 μM).

化合物

GLP-1R Antagonist 1

Cat.No: T15387

Target: Glucagon Receptor

GLP-1R Agonist DMB

Cat.No: T36579

Target: Glucagon Receptor

GLP-1R modulator C16

Cat.No: T40997

Synonym: GLP-1R modulator C16

Target: Glucagon Receptor

GLP-1R modulator L7-028

Cat.No: T40279

Synonym: GLP-1R modulator L7-028

Target: cAMP, Glucagon Receptor

Cat.No: T19850

Synonym: 索玛鲁肽,司美格鲁肽,索马鲁肽

Target: Glucagon Receptor

Gulgafafusp alfa

Cat.No: T80565

Cat.No: T76279

Synonym: LY3437943

Target: Glucagon Receptor

Retatrutide sodium salt

Cat.No: T76279L1

Synonym: Retatrutide sodium salt(2381089-83-2 free base),LY3437943 sodium salt

Target: Glucagon Receptor

Cat.No: T17242

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01385	GLP1R Protein, Human, Recombinant (His) Glucagon-like peptide 1 receptor,GLP1R	Human	HEK293 Cells
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220.
TMPH-03302	GLP1R Protein, Rat, Recombinant (His) Glucagon-like peptide 1 receptor,Glp1r	Rat	P. pastoris (Yeast)
	GLP1R Protein, Rat, Recombinant (His) is expressed in Yeast.
TMPH-02676	GLP1R Protein, Mouse, Recombinant (His & SUMO) Glucagon-like peptide 1 receptor,Glp1r	Mouse	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.4 kDa and the accession number is O35659.
TMPH-01384	GLP1R Protein, Human, Recombinant (E. coli, His) GLP1R,Glucagon-like peptide 1 receptor	Human	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220.
TMPH-03301	GLP1R Protein, Rat, Recombinant (E. coli, His) Glp1r,Glucagon-like peptide 1 receptor	Rat	E. coli
	G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.1 kDa and the accession number is P32301.
TMPY-06864	GLP1R Protein, Human, Recombinant (His & Avi) glucagon-like peptide 1 receptor	Human	HEK293 Cells
	Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of liraglutide, but are not required for glucose-lowering effects. Glucagon-like peptide 1 receptor (GLP1R) signaling has been shown to have antipsychotic properties in animal models and to impact glucose-dependent insulin release, satiety, memory, and learning in man. Glucagon-like p...

重组蛋白

GLP1R Protein, Human, Recombinant (His)

Cat.No: TMPH-01385

Species: Human

Expression System: HEK293 Cells

GLP1R Protein, Rat, Recombinant (His)

Cat.No: TMPH-03302

Species: Rat

Expression System: P. pastoris (Yeast)

GLP1R Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02676

Species: Mouse

Expression System: E. coli

GLP1R Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01384

Species: Human

Expression System: E. coli

GLP1R Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03301

Species: Rat

Expression System: E. coli

GLP1R Protein, Human, Recombinant (His & Avi)

Cat.No: TMPY-06864

Species: Human

Expression System: HEK293 Cells

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