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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T40781 Geranylgeranyl pyrophosphate

Others Others
Geranylgeranyl pyrophosphate, a key metabolite in protein geranylgeranylation, serves as the universal precursor for diterpenoids, such as Paclitaxel. Its role in cancer research stems from this critical function.
T40781L1 Geranylgeranyl pyrophosphate, t-BA (1:2)

Geranylgeranyl pyrophosphate tetrabutylammonium(1:2)(6699-20-3 Free base)

Others Others
Geranylgeranyl pyrophosphate tetrabutylammonium(1:2)是甲羟戊酸途径产生内源性胆固醇和中间体之一。Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) 香叶基香叶基焦磷酸三铵是二萜类化合物的常见前体,例如紫杉醇,可用于癌症研究。
T36863 Geranylgeranyl Pyrophosphate (ammonium salt)

Geranylgeranyl Pyrophosphate (ammonium salt),GGPP

Others Others
Geranylgeranyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway derived directly from farnesyl pyrophosphate and used in the biosynthesis of terpenes and terpenoids.[1] It is also serves as a substrate in the prenylation of a variety of critical intracellular proteins including small GTPases.[2] This post-translational modification is necessary for correct localization of proteins to intracellular membranes for proper functionality and has become a focus of anticancer drug disco...
T40781L Geranylgeranyl pyrophosphate, t-BA (1:1.5)

Others Others
(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl dihydrogen diphosphate,tetrabutylammonium(1:1.5) 是紫杉二烯,如紫杉醇,的常见前体。
T12452 Digeranyl bisphosphonate

DGBP

Rho; Ras Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
Digeranyl bisphosphonate (DGBP) 是一种有效的香叶基焦磷酸香叶酯 (GGPP) 合酶抑制剂,对 Rac1 的香叶基焦磷酸化有抑制作用。Digeranyl bisphosphonate 诱导细胞发生自噬却不诱导细胞凋亡。
T35589 Geranyl pyrophosphate triammonium

Others Others
Geranyl pyrophosphate is an intermediate in the mevalonate pathway. It is formed from dimethylallyl pyrophosphate and isopentenyl pyrophosphate by geranyl pyrophosphate synthase. Geranyl pyrophosphate is used in the biosynthesis of farnesyl pyrophosphate , geranylgeranyl pyrophosphate , cholesterol, terpenes, and terpenoids.
T72989 hGGPPS-IN-3

Apoptosis Apoptosis
hGGPPS-IN-3(Compound 13h)是一种针对人类香叶基香叶基焦磷酸合成酶(hGGPPS)的有效抑制剂,属于C-2取代的噻吩并嘧啶基双膦酸盐(C2-ThP-BPs)衍生物。该化合物能够诱导多发性骨髓瘤(MM)细胞具有选择性地进入凋亡(apoptosis),并且在体内展现了对抗骨髓瘤的活性。
T63906 hGGPPS-IN-2

Others Others
hGGPPS-IN-2 是一种 C-2 取代的噻吩并嘧啶基双膦酸盐 (C2-ThP-BPs) 的类似物,是一种有效的人类香叶基香叶基焦磷酸合成酶 (hGGPPS) 抑制剂。hGGPPS-IN-2 能够靶向作用于多发性骨髓瘤 (MM) 细胞,诱导其选择性凋亡 (apoptosis),并在体内显示出抗骨髓瘤作用。

化合物

Geranylgeranyl pyrophosphate
Cat.No: T40781
Synonym:
Target: Others
Geranylgeranyl pyrophosphate, t-BA (1:2)
Cat.No: T40781L1
Synonym: Geranylgeranyl pyrophosphate tetrabutylammonium(1:2)(6699-20-3 Free base)
Target: Others
Geranylgeranyl Pyrophosphate (ammonium salt)
Cat.No: T36863
Synonym: Geranylgeranyl Pyrophosphate (ammonium salt),GGPP
Target: Others
Geranylgeranyl pyrophosphate, t-BA (1:1.5)
Cat.No: T40781L
Synonym:
Target: Others
Digeranyl bisphosphonate
Cat.No: T12452
Synonym: DGBP
Target: Rho, Ras
Geranyl pyrophosphate triammonium
Cat.No: T35589
Synonym:
Target: Others
hGGPPS-IN-3
Cat.No: T72989
Synonym:
Target: Apoptosis
hGGPPS-IN-2
Cat.No: T63906
Synonym:
Target: Others
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