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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76682 |
Galcanezumab
LY 2951742 |
CGRP Receptor | GPCR/G Protein; Neuroscience |
Galcanezumab 是一种靶向 CGRP 配体的人源化 IgG4 单克隆抗体,是一种与配体降钙素基因相关肽结合的抗体。Galcanezumab 可用于预防和治疗偏头痛或丛集性头痛。 | |||
T75404 |
Galcuronokinase (AtGalAK)
|
Others | Others |
Galcuronokinase (AtGalAK)属于GHMP激酶家族,催化ATP依赖的α-d-半乳糖醛酸(d-GalA)向α-d-半乳糖醛酸-1-磷酸(GalA-1-P)的转化。 | |||
T35450 |
α-GalCer analog 8
α-GalCer analog 8,α-Galactosylceramide analog 8 |
Others | Others |
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 µg per animal dose, indicati... | |||
T74326 |
αGalCer-RBD
|
Others | Others |
αGalCer-RBD 是一种佐剂脂蛋白结合物。αGalCer-RBD 可诱导对 SARS-CoV-2及其变异毒株的有效免疫。αGalCer-RBD 结合物诱导 RBD 特异性、产生细胞因子的 T 细胞发育。αGalCer-RBD 有望成为一种有效的 COVID-19 疫苗候选化合物。α-Galactosylceramide (αGalCer) 是一种有效的不变自然杀伤 T 细胞 (iNKT) 激动剂。 | |||
T21260 |
Psychosine
Sphingosine galactoside,Galactosylsphingosine,Galactosylsphingosine (d18:1) |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Psychosine (Galactosylsphingosine) 是一种 PKC 抑制剂,是半乳糖脑苷脂酶 (GALC) 酶的底物,是 Krabbe 病的潜在生物标志物。Psychosine 具有很强的细胞毒性,可诱导多种细胞死亡。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02667 |
Galactosylceramidase Protein, Mouse, Recombinant
Galactocerebroside beta-galactosidase,Galactocerebrosidase,G... |
Mouse | E. coli |
Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon. |