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Targets Recommended: CGRP Receptor

5

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76682 Galcanezumab

LY 2951742

CGRP Receptor GPCR/G Protein; Neuroscience
Galcanezumab 是一种靶向 CGRP 配体的人源化 IgG4 单克隆抗体,是一种与配体降钙素基因相关肽结合的抗体。Galcanezumab 可用于预防和治疗偏头痛或丛集性头痛。
T75404 Galcuronokinase (AtGalAK)

Others Others
Galcuronokinase (AtGalAK)属于GHMP激酶家族,催化ATP依赖的α-d-半乳糖醛酸(d-GalA)向α-d-半乳糖醛酸-1-磷酸(GalA-1-P)的转化。
T35450 α-GalCer analog 8

α-GalCer analog 8,α-Galactosylceramide analog 8

Others Others
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 &#181g per animal dose, indicati...
T74326 αGalCer-RBD

Others Others
αGalCer-RBD 是一种佐剂脂蛋白结合物。αGalCer-RBD 可诱导对 SARS-CoV-2及其变异毒株的有效免疫。αGalCer-RBD 结合物诱导 RBD 特异性、产生细胞因子的 T 细胞发育。αGalCer-RBD 有望成为一种有效的 COVID-19 疫苗候选化合物。α-Galactosylceramide (αGalCer) 是一种有效的不变自然杀伤 T 细胞 (iNKT) 激动剂。
T21260 Psychosine

Sphingosine galactoside,Galactosylsphingosine,Galactosylsphingosine (d18:1)

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
Psychosine (Galactosylsphingosine) 是一种 PKC 抑制剂,是半乳糖脑苷脂酶 (GALC) 酶的底物,是 Krabbe 病的潜在生物标志物。Psychosine 具有很强的细胞毒性,可诱导多种细胞死亡。

化合物

Galcanezumab
Cat.No: T76682
Synonym: LY 2951742
Target: CGRP Receptor
Galcuronokinase (AtGalAK)
Cat.No: T75404
Synonym:
Target: Others
α-GalCer analog 8
Cat.No: T35450
Synonym: α-GalCer analog 8,α-Galactosylceramide analog 8
Target: Others
αGalCer-RBD
Cat.No: T74326
Synonym:
Target: Others
Psychosine
Cat.No: T21260
Synonym: Sphingosine galactoside,Galactosylsphingosine,Galactosylsphingosine (d18:1)
Target: PKC
Cat. No. Product Name Species Expression System
TMPH-02667 Galactosylceramidase Protein, Mouse, Recombinant

Galactocerebroside beta-galactosidase,Galactocerebrosidase,G...

Mouse E. coli
Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.

重组蛋白

Galactosylceramidase Protein, Mouse, Recombinant
Cat.No: TMPH-02667
Species: Mouse
Expression System: E. coli
TargetMol Loading
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