Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12850 |
Dilmapimod
SB-681323,GW 681323,度马莫得 |
p38 MAPK; Autophagy | Autophagy; MAPK |
Dilmapimod (SB-681323) 是一种 p38 MAPK 的强效抑制剂,可抑制慢性阻塞性肺疾病的炎症。 | |||
T68297 |
Dilmapimod tosylate
|
Others | Others |
Dilmapimod tosylate is a potent p38 mitogen-activated protein kinase (MAPK) inhibitor. It was investigated for its anti-inflammatory effect in non-head injury trauma patients at risk for developing acute respiratory distress syndrome. IL-1β was identified as a gene regulated by dilmapimod that could influence c-reactive protein levels. Dilmapimod had been in phase III clinical trials by GlaxoSmithKline for the treatment of rheumatoid arthritis, neuropathic pain, coronary artery disease (CAD) and... |