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Search Results for " gsc cells "
Targets Recommended: AChR

2

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T6397 Atracurium besylate

Tracrium,51W89,BW-33A,苯磺酸阿曲库铵

AChR Neuroscience
Atracurium besylate (51W89) 是一种神经肌肉阻断剂,ED95为0.2 mg/kg。
T21842 2-fluoro Palmitic Acid

Others Others
2-Fluoropalmitic acid, 是一种酰基辅酶 A 合成酶抑制剂,是一种候选的抗神经胶质瘤的药物。 2-Fluoropalmitic acid 抑制胶质瘤干细胞 (GSC) 活力和干细胞样表型。 2-Fluoropalmitic acid 还抑制神经胶质瘤细胞系的增殖和侵袭。

化合物

Atracurium besylate
Cat.No: T6397
Synonym: Tracrium,51W89,BW-33A,苯磺酸阿曲库铵
Target: AChR
2-fluoro Palmitic Acid
Cat.No: T21842
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPK-00732 WISP1/CCN4 Protein, Mouse, Recombinant (His)

ELM-1,WISP1tc,WISP1c,CCN4,WISP-1,WISP1i

Mouse HEK293 Cells
The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. WISP1 is preferentially expressed and secreted by GSCs. Silencing WISP1 markedly disrupts GSC maintenance, reduces tumor-supportive TAMs (M2), and potently inhibits GBM growth. WISP1 signals through Integrin α6β1-Akt to maintain GSCs by an autocrine mechanism and M2 TAMs through a paracrine manner.

重组蛋白

WISP1/CCN4 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00732
Species: Mouse
Expression System: HEK293 Cells
TargetMol Loading
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