Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11401 |
GKA50
|
Others | Others |
GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats. GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose). | |||
T63019 |
GKA50 quarterhydrate
|
Others | Others |
GKA50 quarterhydrate 是一种有效的葡萄糖激酶激活剂,其 EC50 值为 33 nM。GKA50 quarterhydrate 是一种啮齿动物和人类胰岛中 β 细胞代谢的葡萄糖样激活剂,也是一种 Ca2+依赖性胰岛素分泌调节剂。GKA50 quarterhydrate 能够刺激小鼠胰岛分泌胰岛素,可以显著降低高脂喂养的雌性大鼠血糖。 |