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Targets Recommended: Transferase

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Cat. No. Product Name Target Signaling Pathways
T24088 GGTI-2133

GGTI2133,GGTI 2133

Transferase Metabolism
GGTI-2133 是一种有效的仿肽基香叶基转移酶 I 型抑制剂(GGTase I),IC50值为38 nM。GGTI-2133 可抑制小鼠实验性哮喘中炎症细胞向气道的侵袭。
T85180 GGTI 2133 TFA

Others Others
GGTI 2133, a peptidomimetic inhibitor of geranylgeranyl transferase type I (GGTase I; IC50= 38 nM), exhibits 140-fold selectivity towards GGTase I compared to farnesyltransferase (IC50= 5,400 nM). The compound effectively inhibits the geranylgeranylation of RAP1A (IC50= 10 µM) without affecting the farnesylation of H-Ras (IC50= >30 µM). Moreover, GGTI 2133 reduces the growth, migration, and invasion of oral squamous cell carcinoma (OSSC) cells to 75, 45, and 27% of control levels, respectively. ...

化合物

GGTI-2133
Cat.No: T24088
Synonym: GGTI2133,GGTI 2133
Target: Transferase
GGTI 2133 TFA
Cat.No: T85180
Synonym:
Target: Others
TargetMol Loading
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