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Search Results for " gfp "

Targets Recommended: ATPase RSV

31

抑制剂 & 化合物

1

天然产物

2

TargetMol 试剂盒

7

重组蛋白

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Cat. No.	Product Name	Form	Specificity Of Inhibition
C0122B	GFP Tag Immunomagnetic Beads GFP Tag 免疫沉淀磁珠	Suspension in bottle	IP, Co-IP
C0122	GFP Tag Immunoprecipitation Kit GFP Tag 免疫沉淀试剂盒	Suspension in bottle	IP, Co-IP

TargetMol 试剂盒

GFP Tag 免疫沉淀磁珠

Cat.No: C0122B

GFP Tag 免疫沉淀试剂盒

Cat.No: C0122

Cat. No.	Product Name	Target	Signaling Pathways
T2621	Rostafuroxin PST 2238	ATPase; RSV	Membrane transporter/Ion channel; Microbiology/Virology
	Rostafuroxin (PST 2238) 是洋地黄毒苷衍生物，是一种口服有效的 Na+,K+-ATPase 抑制剂，具有抗高血压和抗 RSV 活性，用于研究治疗原发性高血压的试验。
T19459	N1-Methylpseudouridine N1-甲基-假尿苷,1-Methylpseudouridine	Others	Others
	N1-Methylpseudouridine (1-Methylpseudouridine) 是一种甲基假尿苷，翻译性能比 5 mC 和 5 mC/N1-Methylpseudouridine 高。通过提高核糖体密度，mRNA 中的 N1-Methylpseudouridine 以 eIF2α 依赖性和独立机制增强翻译。
T9120	HBC Benzeneacetonitrile, 4-cyano-α-[[4-[(2-hydroxyethyl)methylamino]phenyl]methylene]-,HBC 530	Others	Others
	HBC (HBC 530) 530 是绿色荧光蛋白 (GFP) 类荧光团的合成染料，具有结构刚性的电子受体和强电子供体。它能够用于 RNA 定位的检测。
T8903	Retro-2 Retro 2,2-{[(5-methyl-2-thienyl)methylene]amino}	Others; Virus Protease; Parasite; Autophagy	Autophagy; Microbiology/Virology; Others
	Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) 是一种植物毒素蓖麻毒素抑制剂，它保护 HeLa 细胞免受蓖麻毒素、Stx1 和 Stx2 的侵害，选择性地阻断早期内体蛋白质-高尔基体界面处的逆行毒素运输。
T78416	GFP150 TFA
	GFP150 TFA是一种用于蛋白标记的绿色荧光蛋白。
T6286	RGFP966 (E-isomer)	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	RGFP966 是一种 HDAC3 抑制剂，IC50 为 0.08 μM，比其他 HDAC 选择性高 200 倍以上。
T1762	RGFP966 RGFP 966	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	RGFP966 是一种能够透过血脑屏障的高选择性HDAC3抑制剂，IC50为 80 nM。
T82494	eGFP mRNA-LNP
	eGFP mRNA-LNP 是一种蕴含eGFP mRNA 的脂质纳米粒，应用于RNA传递、翻译效率及细胞活力的测定。eGFP circRNA携带eGFP以实现绿色荧光蛋白表达，此蛋白可经由荧光显微镜或流式细胞术进行检测，充当报告基因。
T82495	eGFP mRNA(N1-Me-Pseudo UTP)
	eGFP mRNA可以在哺乳动物细胞培养中直接表达出明亮的绿色荧光蛋白，该荧光蛋白源自水母Aequorea victoria，并在509 nm的激发光下发出绿色荧光。作为一种常用的报告蛋白，eGFP用于检测基因表达。
T82496	eGFP circRNA-LNP
	eGFP circRNA-LNP 是一种含有eGFP circRNA 的脂质纳米粒，可用于RNA传递、翻译效率和细胞活力检测。该eGFP circRNA包括增强型绿色荧光蛋白标签，为细胞内绿色荧光蛋白的表达提供基础，且eGFP作为报告基因，可通过荧光显微镜或流式细胞术进行检测。
T40400	Enhanced Green Fluorescent Protein (EGFP) (200-208)
	Enhanced Green Fluorescent Protein (EGFP) (200-208) is a reporter protein obtained from Aequorea Victoria jellyfish. EGFP is widely used as a marker gene product due to its strong fluorescence properties, making it easily detectable.
T82497	eGFP circRNA
	eGFP circRNA，能够编码由Aequorea victoria水母分离得到的绿色荧光蛋白。作为哺乳动物细胞培养中的常规直接检测报告蛋白，其在509 nm波长下发出鲜明的绿光。eGFP circRNA作为环状RNA转染的首选阳性对照，对于监测及提升转染效率具有重要意义。
T13869L	Ribocil	Antibacterial	Microbiology/Virology
	Ribocil 强烈抑制GFP 表达, EC50值为0.3 μM，是一种高选择性化学调节剂，调节细菌核糖核黄素核开关。
T38851	SiR-COOH
	SiR-COOH 可用于跟踪 GFP 细胞中治疗药物模型的细胞内位置（Abs，645 nm；Em，676 nm）。
T4339	YU238259	DNA-PK; Others	DNA Damage/DNA Repair; Others; PI3K/Akt/mTOR signaling
	YU238259 是一种新型的同源依赖性 DNA 修复 (HDR) 抑制剂，在基于细胞的 GFP 报告基因检测中不抑制非同源末端连接 (NHEJ)，可研究癌症。
T15106	DFHBI	Others	Others
	DFHBI 是类似于绿色荧光蛋白发色团的小分子。 Spinach-DFHBI 复合物在体外和活细胞中都具有明亮的荧光，而pinach 和 DFHBI 在未结合时基本不发荧光。
T68405	KW-2450 free base	IGF-1R	Tyrosine Kinase/Adaptors
	KW-2450 free base 是一种 IGF-1R/IR和酪氨酸激酶多重抑制剂具有抗肿瘤活性。KW-2450 free base 在小鼠 HT-29/GFP 结肠癌异种移植模型中显示出适度的生长抑制活性并抑制 IGF-1 诱导的信号转导。
T27240	Eeyarestatin I	Apoptosis	Apoptosis
	Eeyarestatin I 是具有抑制内质网相关蛋白质降解和蛋白易位的抑制剂。Eeyarestatin I 与p97去泛素过程相关，抑制atx3的去泛素化。Eeyarestatin I 通过诱导蛋白质使细胞死亡，具有抗癌作用。
T84801	LNP Lipid-8	Others	Others
	LNP Lipid-8 (11-A-M)为一种可电离脂质，无需靶向配体即可通过脂质纳米颗粒(LNP)将siRNA递送至T细胞。在小鼠模型中，装载siGFP的LNP Lipid-8能显著导致GFP基因沉默。
T77926	PROTAC KRAS G12C degrader-1	PROTACs	PROTAC
	PROTACKRAS G12C degrader-1是基于Cereblon的KRASG12C PROTAC降解剂，能诱导CRBN/KRASG12C二聚化，并在报告细胞中降解GFP-KRASG12C。
T13311	Vps34-IN-2	PI3K	PI3K/Akt/mTOR signaling
	Vps34-IN-2 is a potent and selective Vps34 inhibitor (IC50s: 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively).
T17996	VH032-PEG5-C6-Cl HaloPROTAC 2	Others	Others
	VH032-PEG5-C6-Cl (HaloPROTAC 2) is a small molecule HaloPROTAC that incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T38158	StA-IFN-1	Others	Others
	StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKβ component of the IFN induction pathway. It does not show inhibitory activity in a GFP reporter assay for IFN signaling in which ruxolitinib , which is specific for the IFN signaling component JAK1, is active. StA-IFN-1 reduces the levels of IFN-β, but not ISG MxA, mRNA, suggesting that it is selective f...
T17910	(S,R,S)-AHPC-PEG2-C4-Cl E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl	Others	Others
	(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T17926	(S,R,S)-AHPC-PEG6-C4-Cl VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9,VH032-PEG6-C4-Cl	Others	Others
	(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T38300	Acetyl-L-Homoserine lactone	Others	Others
	Acetyl-L-homoserine lactone belongs to the family of N-acylated homoserine lactones (HSLs) and has an acyl chain length of two carbons. HSLs perform a role in quorum sensing; however, unlike other HSLs, acetyl-L-homoserine lactone does not elicit a response in bacteria. In an assay of carbapenem antibiotic biosynthesis, acetyl-L-homoserine lactone does not induce a response in E. carotovora. In a fluorescence assay using E. coli containing a reporter plasmid of GFP expression in response to exog...
T17911	(S,R,S)-AHPC-C6-PEG3-C4-Cl VH032-C6-PEG3-C4-Cl,VHL Ligand-Linker Conjugates 12,E3 ligase Ligand-Linker Conjugates 8	Others	Others
	(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T41192	CNV Dopamine	Others	Others
	CNV Dopamine is a carboxynitroveratryl (CNV)-caged dopamine; releases dopamine upon ultraviolet light stimulation (365 nm). Induces dopaminergic currents upon photolysis in brain slices expressing wild-type or GFP-labeled D2receptors. Displays no decrease in current (rundown) with UV light flash duration of up to 100 ms. Pharmacologically inactive prior to photolysis.
T36856	UA 62784	Others	Others
	Inhibitor of microtubule polymerization in vitro. Interacts with tubulin dimers and promotes the accumulation of mammalian cells in apoptosis. Potentiates antiproliferative effects of vinblastine in H2B-GFP HeLa cells. Originally thought to inhibit CENP-E ATPase activity. Tcherniuk et al (2011) UA62784 is a cytotoxic inhibitor of microtubules, not CENP-E. Chem.Biol. 18 631 PMID:21609844 \|Maiato and Logarinho et al (2011) Motor-dependent and -independent roles of CENP-E at kinetochores: the cauti...
T17912	(S,R,S)-AHPC-(C3-PEG)2-C6-Cl VHL Ligand-Linker Conjugates 11,E3 ligase Ligand-Linker Conjugates 11	Others	Others
	(S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
T84893	Senexin A hydrochloride	Others	Others
	Senexin A hydrochloride是一种专门针对CDK8/19（IC50为280 nM，针对CDK8）的抑制剂，同时针对p21转录活性下游展现抑制作用。该化合物特异性抑制由p21诱导的转录活性，而不干扰p21的其他生物功能。此外，Senexin A hydrochloride能够抑制CMV-GFP引发的活性及p21激活的、具NF-κB依赖性启动子的表达。

化合物

Cat.No: T2621

Synonym: PST 2238

Target: ATPase, RSV

N1-Methylpseudouridine

Cat.No: T19459

Synonym: N1-甲基-假尿苷,1-Methylpseudouridine

Target: Others

Cat.No: T9120

Synonym: Benzeneacetonitrile, 4-cyano-α-[[4-[(2-hydroxyethyl)methylamino]phenyl]methylene]-,HBC 530

Target: Others

Cat.No: T8903

Synonym: Retro 2,2-{[(5-methyl-2-thienyl)methylene]amino}

Target: Others, Virus Protease, Parasite, Autophagy

Cat.No: T78416

RGFP966 (E-isomer)

Cat.No: T6286

Target: HDAC

Cat.No: T1762

Synonym: RGFP 966

Target: HDAC

Cat.No: T82494

eGFP mRNA(N1-Me-Pseudo UTP)

Cat.No: T82495

eGFP circRNA-LNP

Cat.No: T82496

Enhanced Green Fluorescent Protein (EGFP) (200-208)

Cat.No: T40400

Cat.No: T82497

Cat.No: T13869L

Target: Antibacterial

Cat.No: T38851

Cat.No: T4339

Target: DNA-PK, Others

Cat.No: T15106

Target: Others

KW-2450 free base

Cat.No: T68405

Target: IGF-1R

Cat.No: T27240

Target: Apoptosis

Cat.No: T84801

Target: Others

PROTAC KRAS G12C degrader-1

Cat.No: T77926

Target: PROTACs

Cat.No: T13311

Target: PI3K

VH032-PEG5-C6-Cl

Cat.No: T17996

Synonym: HaloPROTAC 2

Target: Others

Cat.No: T38158

Target: Others

(S,R,S)-AHPC-PEG2-C4-Cl

Cat.No: T17910

Synonym: E3 ligase Ligand-Linker Conjugates 10,VHL Ligand-Linker Conjugates 7,VH032-PEG2-C4-Cl

Target: Others

(S,R,S)-AHPC-PEG6-C4-Cl

Cat.No: T17926

Synonym: VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9,VH032-PEG6-C4-Cl

Target: Others

Acetyl-L-Homoserine lactone

Cat.No: T38300

Target: Others

(S,R,S)-AHPC-C6-PEG3-C4-Cl

Cat.No: T17911

Synonym: VH032-C6-PEG3-C4-Cl,VHL Ligand-Linker Conjugates 12,E3 ligase Ligand-Linker Conjugates 8

Target: Others

Cat.No: T41192

Target: Others

Cat.No: T36856

Target: Others

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl

Cat.No: T17912

Synonym: VHL Ligand-Linker Conjugates 11,E3 ligase Ligand-Linker Conjugates 11

Target: Others

Senexin A hydrochloride

Cat.No: T84893

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T38097	Antibiotic PF 1052	Others	Others
	Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively), among others.1 It inhibits neutrophil migration in a wound assay using zebrafish larvae expressing GFP-labeled neutrophils, reducing pseudopodia formation and inducing rounding of neutrophils.2 Antibiotic PF 1052 is selective for neutrophil migration over macrophage migration in zebrafish larvae. It also in...

天然产物

Antibiotic PF 1052

Cat.No: T38097

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02451	GFP Protein, Aequorea victoria, Recombinant (aa 2-238, His) GFP Protein	Aequorea victoria	E. coli
	GFP Protein, Aequorea victoria, Recombinant (aa 2-238, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.7 kDa and the accession number is AAB65663.
TMPY-04335	GFP Protein, Aequorea victoria, Recombinant (His) GFP Protein	Aequorea victoria	E. coli
	GFP Protein, Aequorea victoria, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27.7 kDa and the accession number is AAB65663.
TMPH-00057	asFP595 Protein, Anemonia sulcata, Recombinant (GST) GFP-like non-fluorescent chromoprotein FP595,asFP59...	Anemonia sulcata	E. coli
	Pigment protein that is intensely purple in color.
TMPH-00058	asFP595 Protein, Anemonia sulcata, Recombinant (hFc) GFP-like non-fluorescent chromoprotein FP595,asFP59...	Anemonia sulcata	HEK293 Cells
	Pigment protein that is intensely purple in color.
TMPY-06965	Claudin-6 Protein, Human, Recombinant (GFP & His) claudin 6	Human	HEK293 Cells
	Claudin-6 Protein, Human, Recombinant (GFP & His) is expressed in HEK293 mammalian cells with GFP and His tag. The predicted molecular weight is 23.3 kDa and the accession number is P56747-1.
TMPY-06806	GPRC5D Protein-VLP, Human, Recombinant (GFP) GPRC5D	Human	HEK293 Cells
	GPRC5D Protein, Human, Recombinant, Fluorescent is expressed in HEK293 mammalian cells. The predicted molecular weight is 65.81 kDa and the accession number is Q9NZD1.
TMPY-01189	GFPT1 Protein, Human, Recombinant GFAT1,CMSTA1,GFAT,glutamine--fructose-6-phosphate transamina...	Human	E. coli
	Glutamine:fructose-6-phosphate amidotransferase 1 (GFAT), also known as GFPT1, is a member of the N-terminal nucleophile aminotransferases and the first rate-limiting enzyme for the entry of glucose into the hexosamine biosynthesis pathway (HBP) in mammals. GFAT transfers the amino group from the L-glutamine amide to the D-fructose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate. GFAT exists as a homotetramer in cytoplasm, and is proposed to be most likely involved in re...

重组蛋白

GFP Protein, Aequorea victoria, Recombinant (aa 2-238, His)

Cat.No: TMPY-02451

Species: Aequorea victoria

Expression System: E. coli

GFP Protein, Aequorea victoria, Recombinant (His)

Cat.No: TMPY-04335

Species: Aequorea victoria

Expression System: E. coli

asFP595 Protein, Anemonia sulcata, Recombinant (GST)

Cat.No: TMPH-00057

Species: Anemonia sulcata

Expression System: E. coli

asFP595 Protein, Anemonia sulcata, Recombinant (hFc)

Cat.No: TMPH-00058

Species: Anemonia sulcata

Expression System: HEK293 Cells

Claudin-6 Protein, Human, Recombinant (GFP & His)

Cat.No: TMPY-06965

Species: Human

Expression System: HEK293 Cells

GPRC5D Protein-VLP, Human, Recombinant (GFP)

Cat.No: TMPY-06806

Species: Human

Expression System: HEK293 Cells

GFPT1 Protein, Human, Recombinant

Cat.No: TMPY-01189

Species: Human

Expression System: E. coli

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