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Targets Recommended: Others

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抑制剂 & 化合物

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天然产物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T74160 UDP-glucosamine disodium

Others Others
UDP-glucosamine (UDP-GlcNAc) disodium 是一种化合物,作为O-GlcNAc转移酶的底物,负责催化O-GlcNAc与蛋白质的结合。同时,O-GlcNAc酶则负责催化从蛋白质中移除O-GlcNAc。作为己糖胺生物合成途径的终产物,UDP-glucosamine (UDP-GlcNAc) disodium主要受葡萄糖-6-磷酸-谷氨酰胺:果糖-6-磷酸氨基转移酶(GFAT)的调节。

化合物

UDP-glucosamine disodium
Cat.No: T74160
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T78485 D-Glucosamine 6-phosphate

Glucosamine-6-phosphate

Endogenous Metabolite Metabolism
D-Glucosamine 6-phosphate为内源性代谢分子,谷氨酰胺果糖-6-磷酸氨基转移酶(GFAT)介导合成。该化合物常用于糖尿病研究领域。
T0429 Glucosamine

Chitosamine,D-Glucosamine,氨基葡萄糖,葡糖胺

MMP; Others; TNF; NF-κB; Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; Endogenous Metabolite; CFTR; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB; Others; Proteases/Proteasome
Glucosamine (Chitosamine) 是软骨基质和滑液中糖胺聚糖的天然成分,常用作骨关节炎的治疗方法。它也是一种氨基糖,是糖基化蛋白和脂质生化合成的突出前体,用作膳食补充剂。

天然产物

D-Glucosamine 6-phosphate
Cat.No: T78485
Synonym: Glucosamine-6-phosphate
Target: Endogenous Metabolite
Glucosamine
Cat.No: T0429
Synonym: Chitosamine,D-Glucosamine,氨基葡萄糖,葡糖胺
Target: MMP, Others, TNF, NF-κB, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, CFTR, Autophagy
Cat. No. Product Name Species Expression System
TMPY-01189 GFPT1 Protein, Human, Recombinant

GFAT1,CMSTA1,GFAT,glutamine--fructose-6-ph...

Human E. coli
Glutamine:fructose-6-phosphate amidotransferase 1 (GFAT), also known as GFPT1, is a member of the N-terminal nucleophile aminotransferases and the first rate-limiting enzyme for the entry of glucose into the hexosamine biosynthesis pathway (HBP) in mammals. GFAT transfers the amino group from the L-glutamine amide to the D-fructose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate. GFAT exists as a homotetramer in cytoplasm, and is proposed to be most likely involved in re...

重组蛋白

GFPT1 Protein, Human, Recombinant
Cat.No: TMPY-01189
Species: Human
Expression System: E. coli
TargetMol Loading
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