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Search Results for " g36 "

Targets Recommended: Estrogen Receptor/ERR

29

抑制剂 & 化合物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T22794	G36 G-36	Estrogen Receptor/ERR	Endocrinology/Hormones
	G36是一种细胞可渗透的G 蛋白偶联雌激素受体(GPER/GPR30)的非甾体拮抗剂。G36抑制17β-雌二醇或GPER 选择性激动剂G-1的激活（IC50分别为112和165 nM）。G36对ERα或ERβ均无可检测的结合活性。G36通过GPER 阻断由雌激素触发的PI3K 的激活或钙动员，并且它通过雌激素或G-1而不是通过EGF 抑制ERK 的激活。
T18404	N-Boc-PEG36-alcohol	Others	Others
	N-Boc-PEG36-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17857	DSPE-PEG36-mal	Others	Others
	DSPE-PEG36-mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18282	Mal-PEG36-NHS ester	Others	Others
	Mal-PEG36-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T80737	ZG36	Others	Others
	ZG36是一种人类Caseinolytic protease P(ClpP)激动剂，具有非选择性地降解呼吸链复合物和减少线粒体DNA的能力，从而导致线粒体功能衰竭及白血病细胞死亡。此外，ZG36能够抑制异种移植小鼠模型中急性髓细胞性白血病的发展。
T17433	Amino-PEG36-CONH-PEG36-acid	Others	Others
	Amino-PEG36-CONH-PEG36-acid is a polyethylene glycol (PEG)-based linker with amino and carboxylic acid functionalities. It finds utility in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T18191	m-PEG36-amine	Others	Others
	m-PEG36-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18190	m-PEG36-alcohol	Others	Others
	m-PEG36-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17510	Azido-PEG36-acid	Others	Others
	Azido-PEG36-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17511	Azido-PEG36-alcohol	Others	Others
	Azido-PEG36-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17577	Biotin-PEG36-acid	Others	Others
	Biotin-PEG36-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18193	m-PEG36-Br	Others	Others
	m-PEG36-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17432	Amino-PEG36-CH2-Boc	Others	Others
	Amino-PEG36-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17962	Fmoc-N-PEG36-acid	Others	Others
	Fmoc-N-amido-PEG36-acid is a polyethylene glycol (PEG)-based linker utilized in PROTAC synthesis. It has been designed specifically for constructing PROTACs, which are bifunctional molecules capable of recruiting target proteins to an E3 ubiquitin ligase for degradation[1].
T17430	Amino-PEG36-alcohol	Others	Others
	Amino-PEG36-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T77836	APN-PEG36-tetrazine	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	APN-PEG36-tetrazine是APN-PEG4-tetrazine的类似物，后者作为具有可降解(cleavable)特性的含四个单元PEG的ADC linker，应用于抗体偶联活性分子(ADC)的合成。
T18510	OPSS-PEG36-acid	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	OPSS-PEG36-acid is a 36-unit PEG linker amenable to cleavage, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].
T17429	Amino-PEG36-acid	Others	Others
	Amino-PEG36-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17856	DSPE-PEG36-DBCO	Others	Others
	DSPE-PEG36-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18771	TCO-PEG36-acid	Others	Others
	TCO-PEG36-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17723	Cbz-NH-PEG36-C2-acid	Others	Others
	Cbz-NH-PEG36-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18713	SPDP-PEG36-NHS ester	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	SPDP-PEG36-NHS ester is a PEG ADC linker consisting of 36 units, characterized by cleavability. It plays a crucial role in the synthesis of antibody-drug conjugates (ADCs)[1].
T17678	Boc-NH-PEG36-CH2CH2COOH	Others	Others
	Boc-NH-PEG36-CH2CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker employed for the synthesis of PROTACs[1].
T18195	m-PEG36-OH	Others	Others
	m-PEG36-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17512	Azido-PEG36-Boc	Others	Others
	Azido-PEG36-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17431	Amino-PEG36-Boc	Others	Others
	Amino-PEG36-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18194	m-PEG36-Mal	Others	Others
	m-PEG36-Mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17578	Biotin-PEG36-PFP ester	Others	Others
	Biotin-PEG36-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18192	m-PEG36-azide	Others	Others
	m-PEG36-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

化合物

Cat.No: T22794

Synonym: G-36

Target: Estrogen Receptor/ERR

N-Boc-PEG36-alcohol

Cat.No: T18404

Target: Others

Cat.No: T17857

Target: Others

Mal-PEG36-NHS ester

Cat.No: T18282

Target: Others

Cat.No: T80737

Target: Others

Amino-PEG36-CONH-PEG36-acid

Cat.No: T17433

Target: Others

Cat.No: T18191

Target: Others

m-PEG36-alcohol

Cat.No: T18190

Target: Others

Azido-PEG36-acid

Cat.No: T17510

Target: Others

Azido-PEG36-alcohol

Cat.No: T17511

Target: Others

Biotin-PEG36-acid

Cat.No: T17577

Target: Others

Cat.No: T18193

Target: Others

Amino-PEG36-CH2-Boc

Cat.No: T17432

Target: Others

Fmoc-N-PEG36-acid

Cat.No: T17962

Target: Others

Amino-PEG36-alcohol

Cat.No: T17430

Target: Others

APN-PEG36-tetrazine

Cat.No: T77836

Target: Others, ADC Linker

OPSS-PEG36-acid

Cat.No: T18510

Target: Others, ADC Linker

Amino-PEG36-acid

Cat.No: T17429

Target: Others

DSPE-PEG36-DBCO

Cat.No: T17856

Target: Others

Cat.No: T18771

Target: Others

Cbz-NH-PEG36-C2-acid

Cat.No: T17723

Target: Others

SPDP-PEG36-NHS ester

Cat.No: T18713

Target: Others, ADC Linker

Boc-NH-PEG36-CH2CH2COOH

Cat.No: T17678

Target: Others

Cat.No: T18195

Target: Others

Azido-PEG36-Boc

Cat.No: T17512

Target: Others

Amino-PEG36-Boc

Cat.No: T17431

Target: Others

Cat.No: T18194

Target: Others

Biotin-PEG36-PFP ester

Cat.No: T17578

Target: Others

Cat.No: T18192

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00071	Ebola virus EBOV (subtype Zaire, strain Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) Glycoprotein/EBOV-G Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) Glycoprotein/EBOV-G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is A0A068J419.
TMPY-00307	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) EBOV-G/Glycoprotein Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) EBOV-G/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is A0A068J419.

重组蛋白

Ebola virus EBOV (subtype Zaire, strain Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) Glycoprotein/EBOV-G Protein (His)

Cat.No: TMPY-00071

Species: EBOV

Expression System: HEK293 Cells

Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) EBOV-G/Glycoprotein Protein (His)

Cat.No: TMPY-00307

Species: EBOV

Expression System: HEK293 Cells

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