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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36003 |
1(R)-(Trifluoromethyl)oleyl alcohol
|
Others | Others |
1(R)-(Trifluoromethyl)oleyl alcohol is an analog of oleic acid .1It inhibits ferroptosis induced by erastin in primary fibroblasts isolated from patients with Friedreich ataxia, a neuro- and cardiodegenerative disorder characterized by loss or impaired activity of frataxin (FXN), when used at concentrations of 5, 10, or 20 μM. 1(R)-(Trifluoromethyl)oleyl alcohol (5 μM) reduces lipid peroxidation induced byFXNsiRNA knockdown in NBT human myoblasts. 1.Cotticelli, M.G., Forestieri, R., Xia, S., et ... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03295 |
Frataxin/FXN Protein, Rat, Recombinant
Fxn,Frataxin, mitochondrial |
Rat | E. coli |
Frataxin/FXN Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.6 kDa and the accession number is D3ZYW7. | |||
TMPH-02428 |
Frataxin/FXN Protein, Cynomolgus, Recombinant (His)
FXN,Frataxin, mitochondrial |
Cynomolgus | E. coli |
Frataxin Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.2 kDa and the accession number is Q8HXX9. | |||
TMPH-02660 |
Frataxin/FXN Protein, Mouse, Recombinant (His)
Fxn,Frataxin, mitochondrial |
Mouse | P. pastoris (Yeast) |
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activit... | |||
TMPH-01356 |
Frataxin/FXN Protein, Human, Recombinant (His & Myc)
Frataxin, mitochondrial,Friedreich ataxia protein,FXN |
Human | E. coli |
Frataxin/FXN Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa and the accession number is Q16595. | |||
TMPH-02661 |
Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)
Fxn,Frataxin, mitochondrial |
Mouse | E. coli |
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activit... |