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Search Results for " fxn "
Targets Recommended: Others

1

抑制剂 & 化合物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T36003 1(R)-(Trifluoromethyl)oleyl alcohol

Others Others
1(R)-(Trifluoromethyl)oleyl alcohol is an analog of oleic acid .1It inhibits ferroptosis induced by erastin in primary fibroblasts isolated from patients with Friedreich ataxia, a neuro- and cardiodegenerative disorder characterized by loss or impaired activity of frataxin (FXN), when used at concentrations of 5, 10, or 20 μM. 1(R)-(Trifluoromethyl)oleyl alcohol (5 μM) reduces lipid peroxidation induced byFXNsiRNA knockdown in NBT human myoblasts. 1.Cotticelli, M.G., Forestieri, R., Xia, S., et ...

化合物

1(R)-(Trifluoromethyl)oleyl alcohol
Cat.No: T36003
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-03295 Frataxin/FXN Protein, Rat, Recombinant

Fxn,Frataxin, mitochondrial

Rat E. coli
Frataxin/FXN Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.6 kDa and the accession number is D3ZYW7.
TMPH-02428 Frataxin/FXN Protein, Cynomolgus, Recombinant (His)

FXN,Frataxin, mitochondrial

Cynomolgus E. coli
Frataxin Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.2 kDa and the accession number is Q8HXX9.
TMPH-02660 Frataxin/FXN Protein, Mouse, Recombinant (His)

Fxn,Frataxin, mitochondrial

Mouse P. pastoris (Yeast)
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activit...
TMPH-01356 Frataxin/FXN Protein, Human, Recombinant (His & Myc)

Frataxin, mitochondrial,Friedreich ataxia protein,FXN

Human E. coli
Frataxin/FXN Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa and the accession number is Q16595.
TMPH-02661 Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)

Fxn,Frataxin, mitochondrial

Mouse E. coli
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activit...

重组蛋白

Frataxin/FXN Protein, Rat, Recombinant
Cat.No: TMPH-03295
Species: Rat
Expression System: E. coli
Frataxin/FXN Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPH-02428
Species: Cynomolgus
Expression System: E. coli
Frataxin/FXN Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02660
Species: Mouse
Expression System: P. pastoris (Yeast)
Frataxin/FXN Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01356
Species: Human
Expression System: E. coli
Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)
Cat.No: TMPH-02661
Species: Mouse
Expression System: E. coli
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