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Search Results for " fulvestrant "

Targets Recommended: Apoptosis Estrogen Receptor/ERR Estrogen/progestogen Receptor Autophagy

抑制剂 & 化合物

重组蛋白

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T2146	Fulvestrant 氟维司群,ZM 182780,ZD 9238,ICI 182780	Apoptosis; Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones
	Fulvestrant (ZM 182780) 是一种雌激素受体 (ER) 拮抗剂 (IC50=9.4 nM)，也是一种 GPR30 的激动剂。Fulvestrant 具有抗肿瘤活性，可以抑制细胞增殖，诱导细胞凋亡和自噬。
T11335	Fulvestrant (S enantiomer) ZM 182780 S enantiomer,ICI 182780 S enantiomer,Fulvestrant S enantiomer,ZD 9238 S enantiomer	Others	Others
	Fulvestrant S enantiomer is the less active S enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
T11334	Fulvestrant (R enantiomer) ICI 182780 R enantiomer,ZD 9238 R enantiomer,ZM 182780 R enantiomer,Fulvestrant R enantiomer	Others	Others
	Fulvestrant R enantiomer is the less active R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.
T71710	Fulvestrant sulfone	Others	Others
	Fulvestrant sulfone is a synthetic estrogen receptor antagonist.
T82366	Fulvestrant 3-β-D-Glucuronide	Others	Others
	Fulvestrant 3-β-D-Glucuronide，Fulvestrant的代谢产物，为葡萄糖醛酸结合物，属于纯抗雌激素类固醇。该化合物可应用于乳腺癌研究领域。
T71578	Endoxifen mesylate	Others	Others
	Endoxifen, also known as N-desmethyl-4-hydroxytamoxifen, is a chemical that is under development for estrogen receptor-positive breast cancer. It is also being evaluated as an antipsychotic for treatment of mania and other psychotic disorders. Endoxifen is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group. It is an active metabolite of tamoxifen and has been found to be effective in patients that have failed previous hormonal therapies (tamoxifen, aromat...

化合物

Fulvestrant

Cat.No: T2146

Synonym: 氟维司群,ZM 182780,ZD 9238,ICI 182780

Target: Apoptosis, Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Autophagy

Fulvestrant (S enantiomer)

Cat.No: T11335

Synonym: ZM 182780 S enantiomer,ICI 182780 S enantiomer,Fulvestrant S enantiomer,ZD 9238 S enantiomer

Target: Others

Fulvestrant (R enantiomer)

Cat.No: T11334

Synonym: ICI 182780 R enantiomer,ZD 9238 R enantiomer,ZM 182780 R enantiomer,Fulvestrant R enantiomer

Target: Others

Fulvestrant sulfone

Cat.No: T71710

Synonym:

Target: Others

Fulvestrant 3-β-D-Glucuronide

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01576	Artemin Protein, Mouse, Recombinant (hFc) artemin,neublastin	Mouse	HEK293 Cells
	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored GDNF family receptors a (GFRa1, GFRa3) and RET receptor tyrosine kinase. The major mechanism of ARTN action is via binding to a non-signaling co-receptor. The major function of ARTN is to drive the molecule to induce migration and axonal projection from sympathetic neurons. It a...

重组蛋白

Artemin Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-01576

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0244	Fulvestrant-d3
	Fulvestrant-d3 是 Fulvestrant 的氘代化合物。Fulvestrant 的 CAS 号为 129453-61-8。Fulvestrant是纯抗雌激素，也是一种雌激素受体拮抗剂，IC50为 9.4 nM。它抑制ER阳性 MCF-7 细胞的生长，IC50为 0.29 nM。它还是一种GPR30的激动剂。它可诱导细胞自噬和凋亡，有抗肿瘤作用。

同位素标记化合物

Fulvestrant-d3

Cat.No: TMIJ-0244

Synonym:

Target:

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化合物

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同位素标记化合物