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Search Results for " fms like tyrosine kinase 3 "
Targets Recommended: Apoptosis FLT c-RET TAM Receptor Aurora Kinase

62

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Cat. No. Product Name Target Signaling Pathways
T2620 G-749

G749

Apoptosis; FLT; c-RET; TAM Receptor; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
G-749 是一种新型 FLT3 抑制剂,对 FLT3 野生型和突变体有持续的抑制作用,IC50值分别为 0.4 nM 和 0.6 nM。它可用于急性髓系白血病的耐药研究。
T11298 FLT3-IN-3

FLT Angiogenesis; Tyrosine Kinase/Adaptors
FLT3-IN-3 是 FLT3抑制剂,能够抑制 FLT3 WT (IC50:13 nM) 和 FLT3 D835Y (IC50:8 nM) 。
T2340 AC1NS4RE

Tyrosinase Proteases/Proteasome
是一种化学合成中的砌块
T4209 TAK-659 hydrochloride

TAK-659

VEGFR; FLT; Tyrosine Kinases; JAK; Syk Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
TAK-659 hydrochloride (TAK-659) 是可逆的、高效的、选择性的、口服有效的 SYK/FLT3 双抑制剂,对 SYK 和 FLT3 作用的IC50值分别为 3.2 nM、4.6 nM。它能诱导肿瘤细胞死亡,却不作用于非肿瘤细胞,对慢性淋巴细胞白血病具有潜在的研究价值。
T1938 FLT3-IN-2

FLT Angiogenesis; Tyrosine Kinase/Adaptors
FLT3-IN-2 是 FLT3 抑制剂(IC50<1 μM)。
T4428 CCT241736

FLT; Aurora Kinase Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
CCT241736 是一种口服生物可利用的双重 FLT3/Aurora 激酶抑制剂,还抑制临床相关的 FLT3 耐药突变体,包括 FLT3-ITD 和 FLT3。它是 CCT137690 的高级类似物,是治疗人类恶性肿瘤的临床前开发候选物。
T15335 FN-1501

FLT; CDK Angiogenesis; Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
FN-1501 是一种有效的 FLT3 和 CDK 抑制剂,具有抗肿瘤的活性,对 CDK2/cyclin A、CDK4/cyclin D1、CDK6/cyclin D1 和 FLT3 的 IC50值分别为 2.47、0.85、1.96 和 0.28 nM。
T6756 AMG 925

FLT; CDK Angiogenesis; Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
AMG 925 是一种选择性FLT3/CDK4双重抑制剂,IC50分别为 1 nM 和 3 nM。
T6115 Fostamatinib

R788,福他替尼

FLT; Syk; Monoamine Transporter; Adenosine Receptor Angiogenesis; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience; Tyrosine Kinase/Adaptors
Fostamatinib (R788) 是一种口服具有活力的 R406 前药。其中R406 是具有口服活性的,有效的,ATP 竞争性的Syk/FLT3抑制剂(Ki:30 nM,IC50:41 nM),也能够抑制 Lyn (IC50:63 nM) 和 Lck (IC50:37 nM)。
T6020 Pacritinib

SB1518

FLT; Tyrosine Kinases; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Pacritinib (SB1518) 是一种野生型 JAK2和 JAK2V617F 突变型抑制剂,IC50分别为 23 和 19 nM。它也抑制 FLT3及其突变型 FLT3D835Y,IC50分别为 22 和 6 nM。
T3065 TG101209

Apoptosis; FLT; c-RET; JAK; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
TG101209 是一种选择性有效的 JAK2抑制剂,IC50值为 6 nM。它能抑制 Flt3和RET 的活性,IC50值分别为 25 nM 和 17 nM。
T6174 R406

R-406 besylate

Apoptosis; FLT; Syk Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
R406 (R-406 besylate) 是一种具有口服活性的 ATP 竞争性 Syk/FLT3抑制剂,Ki 为 30 nM。它有效抑制 Syk 激酶活性,IC50为 41 nM。它还抑制 Lyn 和 Lck,IC50值分别为 63 nM 和 37 nM。它可减轻免疫复合物介导的炎症。
T2272 BPR1J-097

BPR1J097

FLT Angiogenesis; Tyrosine Kinase/Adaptors
BPR1-J097 是新型的、强效的FLT3抑制剂 (IC50:11 nM)。
T6138 TCS 359

FLT3 Inhibitor

FLT Angiogenesis; Tyrosine Kinase/Adaptors
TCS 359 (FLT3 Inhibitor) 是 2-酰基氨基噻吩-3-甲酰胺,是选择性FLT3抑制剂(IC50:42 nM),能够抑制 MV4-11 细胞增殖(IC50:340 nM)。
T7673 ATH686

ATH 686

Apoptosis; FLT Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
ATH686 是一种选择性的,ATP 竞争性的FLT3抑制剂,具有抗白血病作用。它靶向突变 FLT3 蛋白激酶活性,并通过诱导凋亡和抑制细胞周期来抑制具有 FLT3 突变的细胞的增殖。
T6350 CHIR-124

CHIR124,CHIR 124

Apoptosis; GSK-3; FLT; Chk; PDGFR; Src Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
CHIR-124 是一种选择性 Chk1抑制剂,IC50值为 0.3 nM,可有效抑制 PDGFR 和 FLT3,IC50值分别为 6.6 nM 和 5.8 nM。
T2467 R406 free base

R406 (free base)

Apoptosis; FLT; Syk Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
R406 free base (R406(free base)) 是一种具有口服活性的,ATP 竞争性的Syk/FLT3抑制剂,Ki 为 30 nM。它有效抑制 Syk 激酶活性,IC50为 41 nM,可减轻免疫复合物介导的炎症。它还抑制 Lyn 和 Lck,IC50分别为 63 nM 和 37 nM。
T2341 KW-2449

KW2449

Apoptosis; FGFR; FLT; JAK; Bcr-Abl; Src; c-Kit; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
KW-2449是一种多靶点激酶抑制剂,对FLT3,ABL,ABLT315I 和极光激酶的IC50值分别为6.6,14,4 和 48 nM。
T3455 Merestinib

LY2801653

Discoidin Domain Receptor (DDR); FLT; c-Met/HGFR; ROS; ROS Kinase Angiogenesis; Immunology/Inflammation; Tyrosine Kinase/Adaptors
Merestinib (LY2801653) 是一种有效的口服生物可利用的具有抗肿瘤活性的c-Met 抑制剂。
T9473 4SC-203

FLT Angiogenesis; Tyrosine Kinase/Adaptors
4SC-203 是一种具有潜在的抗肿瘤活性的多激酶抑制剂。它对 FLT3/STK1、 FLT3 的突变形式以及 VEGFRs 具有选择性抑制作用。
T3068 AT9283

J-504568

Apoptosis; FLT; JAK; Bcr-Abl; Aurora Kinase; Autophagy Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
AT9283 (J-504568) 是一种多靶点激酶抑制剂,抑制多种实体瘤在体内外的生长和存活,有效抑制Aurora A/B,JAK2/3,Abl (T315I),和Flt3,IC50值范围为 1-30 nM。
TQ0235 AC710

FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
AC710是一种 PDGFR 抑制剂,能够作用于 FLT3 (Kd:0.6),CSF1R (Kd:1.57),KIT (Kd:1),PDGFRα (Kd:1.3) 和 PDGFRβ (Kd:1.0)。
T9027 CA-4948

Emavusertib

IRAK; FLT Angiogenesis; Immunology/Inflammation; NF-κB; Tyrosine Kinase/Adaptors
CA-4948 (Emavusertib) 是一种IRAK4抑制剂,也是一种FLT3抑制剂,具有抗肿瘤作用。
T2638 Gandotinib

LY2784544

VEGFR; FGFR; FLT; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Gandotinib (LY2784544) 是一种JAK2抑制剂,IC50为 3 nM。它也抑制FLT3、FLT4、FGFR2、TYK2 和 TRKB,IC50分别为 4、25、32、44 和 95 nM。
T2640 Rebastinib

DCC2036,DCC 2036,DCC-2036

Apoptosis; FLT; Bcr-Abl; Src Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Rebastinib (DCC-2036) 是一种口服有效的,非 ATP 竞争性的 Bcr-Abl 抑制剂,作用于 Abl1WT 和 Abl1T315I,IC50分别为 0.8 nM 和 4 nM,还抑制 LYN、SRC、HCK、FGR、FLT3、KDR 和 Tie-2,对 c-Kit 的活性低。Rebastinib 对 Angiopoietin2-Tie2通路具有抑制作用。
T38562 AKN-028

FLT Angiogenesis; Tyrosine Kinase/Adaptors
AKN-028 是酪氨酸激酶 FLT3的抑制剂,可剂量依赖性的诱导 FLT3的自磷酸化。
T4409 Gilteritinib

吉列替尼,ASP2215

FLT; TAM Receptor; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Gilteritinib (ASP2215) 是一种 FLT3 抑制剂 (IC50=0.29 nM),也是一种 AXL 抑制剂 (IC50=0.73 nM),具有 ATP 竞争性、选择性和口服活性。Gilteritinib 具有抗肿瘤活性,可以用于治疗 FLT3 突变阳性的 AML。
T16144 MRX-2843

UNC2371

Others; FLT Angiogenesis; Others; Tyrosine Kinase/Adaptors
MRX-2843 (UNC2371) 是ATP 竞争性的、具有口服活性的MERTK 和FLT3酪氨酸激酶抑制剂 (TKI),它们的IC50分别为 1.3 nM 和 0.64 nM。
T2054 Altiratinib

DCC-2701

VEGFR; Tie-2; FLT; Trk receptor; c-Met/HGFR Angiogenesis; Tyrosine Kinase/Adaptors
Altiratinib (DCC-2701) 是一种多靶点激酶抑制剂,能够抑制 MET (IC50:2.7 nM),TIE2 (IC50:8 nM),VEGFR2 (IC50:9.2 nM),FLT3 (IC50:9.3 nM),Trk1 (IC50:0.85 nM),Trk2 (IC50:4.6 nM) 和 Trk3 (IC50:0.83 nM)。
T7007 UNC2025

mrx-6313,UNC-2025,UNC 2025

FLT; TAM Receptor Angiogenesis; Tyrosine Kinase/Adaptors
UNC2025 (mrx-6313) 是高效的、具有口服活性的、ATP 竞争性的Mer/Flt3双抑制剂,IC50值分别为 0.74 nM 和 0.8 nM。它对MERTK 的选择性比 Axl 高 45 倍(IC50:122 nM;Ki:13.3 nM)。它具有良好的 PK 特性,可用于研究急性白血病。
T2358 ENMD-2076

Apoptosis; VEGFR; FGFR; FLT; c-RET; PDGFR; Src; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
ENMD2076是一种多靶点激酶抑制剂,抑制Aurora A、Flt3、KDR/VEGFR2、Flt4/VEGFR3、FGFR1、FGFR2、Src、PDGFRα的IC50值分别为1.86、14、58.2、15.9、92.7、70.8、20.2 and 56.4 nM。
T0093L Sorafenib

索拉非尼,Bay 43-9006

Apoptosis; Raf; VEGFR; FLT; Ferroptosis; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
Sorafenib (Bay 43-9006) 是一种多激酶抑制剂,抑制 Raf-1、B-Raf、VEGFR2、VEGFR3、VEGFR4、PDGFRβ、FLT3、c-Kit 等 (IC50=6/22/90/15/20/20/57/58 nM),具有口服活性。Sorafenib 具有抗肿瘤活性,可以诱导细胞自噬和凋亡,也可以激动铁死亡。
T1836 AZD2932

VEGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
AZD2932是一种多靶点激酶抑制剂,细胞试验中能够抑制 VEGFR2 (IC50:8 nM),PDGFβ (IC50:4 nM),PDGFβ (IC50:7 nM) 和 PDGFβ (IC50:9 nM)。
T2605 Fostamatinib Disodium

Tamatinib Fosdium,福他替尼二钠盐,R788(Disodium),R788 Disodium,R788 (Fostamatinib) Disodium

FLT; Syk Angiogenesis; Tyrosine Kinase/Adaptors
Fostamatinib Disodium (R788 Disodium) 是一种口服具有活力的 R406 前药。其中R406 是具有口服活性的,有效的,ATP 竞争性的Syk/FLT3抑制剂(Ki:30 nM,IC50:41 nM),也能够抑制 Lyn (IC50:63 nM) 和 Lck (IC50:37 nM)。
T2677 Crenolanib

ARO 002,CP-868596

FLT; PDGFR; Autophagy Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
Crenolanib (ARO 002) 是一种口服生物可利用的 III 型酪氨酸激酶抑制剂,抑制 FLT3和 PDGFRα/β的 IC50分别为 4、11和 3.2 nM。
T41003 KG5

Raf; FLT; PDGFR; c-Kit Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
KG5 是 PDGFRβ 和 B-Raf 的双重变构抑制剂,对 PDGFRβ 和 PDGFRα 的 Kd 分别为 520 nM 和 300 nM。 KG5 抑制 FLT3、KIT 和 c-Raf,具有抗癌和抗血管生成活性。
T0093 Sorafenib tosylate

甲苯磺酸索拉非尼,Bay 43-9006

Apoptosis; Raf; VEGFR; FLT; Ferroptosis; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
Sorafenib tosylate (Bay 43-9006) 是一种多激酶抑制剂,抑制 Raf-1、B-Raf、VEGFR2、VEGFR3、VEGFR4、PDGFRβ、FLT3、c-Kit 等 (IC50=6/22/90/15/20/20/57/58 nM),具有口服活性。Sorafenib 具有抗肿瘤活性,可以诱导细胞自噬和凋亡,也可以激动铁死亡。
T8482 Ripretinib

DCC-2618,瑞普替尼

Apoptosis; VEGFR; FLT; PDGFR; c-Kit Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Ripretinib (DCC-2618) 是一种口服生物利用的,选择性 KIT 和 PDGFRA 开关控制抑制剂,具有抗肿瘤作用并诱导细胞凋亡。它专门针对 KIT 和 PDGFRA 的野生型和突变型并与之结合在其开关口袋结合位点,从而防止这些激酶从无活性构象转变为有活性构象,并使它们的野生型和突变体形式失活。
T4053 AST 487

NVP-AST 487

VEGFR; FLT; c-RET; Bcr-Abl; c-Kit Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
AST 487 (NVP-AST 487) 是 RET 激酶抑制剂 (IC50:880 nM),能够抑制 RET 自磷酸化,及下游效应器激活,也抑制 Flt-3 (IC50:520 nM)。
T2051 SKLB4771

FLT3-​IN-​1,FLT3-IN-1

FLT Angiogenesis; Tyrosine Kinase/Adaptors
SKLB4771 (FLT3-IN-1) 是一种新型的、高效的 Flt3 抑制剂 (IC50:10nM)。
T4349 Sitravatinib

MG516,MGCD516

Discoidin Domain Receptor (DDR); VEGFR; FLT; Trk receptor; TAM Receptor; c-Kit; Ephrin Receptor Angiogenesis; Tyrosine Kinase/Adaptors
Sitravatinib (MGCD516) 是一种有口服活性的受体酪氨酸激酶抑制剂。它单独使用即具有有效的抗肿瘤功效,且通过促进抗肿瘤免疫微环境增强了 PD-1 阻断的活性。
T21503 (E/Z)-Zotiraciclib

(E/Z)-TG02,(E/Z)-SB1317

FLT; JAK; CDK Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
(E/Z)-Zotiraciclib ((E/Z)-TG02) 是一种 CDK2、JAK2和FLT3的抑制剂,IC50分别为 13、73 和 56 nM。
T2066 Quizartinib

AC220,奎扎替尼

Apoptosis; FLT; Autophagy; Ligands for Target Protein for PROTAC Angiogenesis; Apoptosis; Autophagy; PROTAC; Tyrosine Kinase/Adaptors
Quizartinib (AC220) 是一种第二代 Ⅱ 型 FLT3 酪氨酸激酶抑制剂,具有口服活性和高选择性,抑制 FLT3-WT 和 FLT3-ITD 自磷酸化 (IC50=4.1/1.1 nM)。Quizartinib 可以诱导肿瘤细胞凋亡。
T2516 Amuvatinib

MP470,HPK 56

Apoptosis; FLT; c-Met/HGFR; c-RET; DNA/RNA Synthesis; PDGFR; c-Kit Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Tyrosine Kinase/Adaptors
Amuvatinib (MP470) 是一种多靶点酪氨酸激酶抑制剂,对突变 c-Kit,PDGFRα,Flt3,c-Met 和 c-Ret 具有活性。它还是一种 DNA 修复抑制剂,靶向蛋白 DNA 修复 RAD51,从而破坏 DNA 损伤修复,具有抗肿瘤活性。
T6028 PF 477736

PF 00477736,PF-477736,PF-736,PF-00477736,PF477736

c-Fms; VEGFR; FGFR; FLT; c-RET; Chk; CDK; Src; Aurora Kinase Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
PF 477736 (PF-736,PF-00477736) 是一种特异性、有效且具有 ATP 竞争性的 Chk1 抑制剂,Ki 值为0.49 nM。它也是Chk2抑制剂,Ki 值为 47 nM。它还抑制VEGFR2、Fms、Yes、Aurora-A、FGFR3、Flt3和Ret。
T6479 Dovitinib lactate hydrate

Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib lactate hydrate (TKI258) 是一种多靶点的酪氨酸激酶抑制剂,抑制 FLT3,c-Kit,FGFR1/3,VEGFR1/2/3和 PDGFRα/β的 IC50值分别为 1,2,8/9,10/13/8,27/210 nM。
T6711 Tyrphostin AG1296

Tyrphostin AG 1296,AG 1296

Apoptosis; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Tyrphostin AG1296 (Tyrphostin AG 1296) 抑制人PDGF α和β受体以及相关干细胞因子受体的信号传导,是一种选择性血小板衍生生长因子受体抑制剂,IC50值为 0.8 μM。
T6289 Dovitinib

TKI258,多韦替尼,CHIR-258,度维替尼

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib (CHIR-258) 是一种口服有效的、多靶点的酪氨酸激酶 (RTK) 抑制剂,具有抗肿瘤作用。
T2514 Linifanib

利尼伐尼,ABT-869,RG3635,AL-39324

Apoptosis; c-Fms; VEGFR; FLT; CSF-1R; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; Tyrosine Kinase/Adaptors
Linifanib (AL-39324) 是一种高效口服的VEGFR 和PDGFR 家族多靶点抑制剂,具有显著的抗肿瘤活性。它对无关 RTKs、可溶性酪氨酸激酶或丝氨酸/苏氨酸激酶的活性要低得多。它是特异性 miR-10b 抑制剂,阻断miR-10b 的生物合成。
T1667 Tandutinib

MLN518,CT53518,NSC726292,坦度替尼

Apoptosis; FLT; CSF-1R; PDGFR; Src; c-Kit Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Tandutinib (CT53518) 是一种选择性 FLT3抑制剂,其 IC50为 0.22 μM。它还抑制c-Kit 和PDGFR,其IC50分别为 0.17 μM 和 0.20 μM。它可穿透血脑屏障,用于急性骨髓性白血病。

化合物

G-749
Cat.No: T2620
Synonym: G749
Target: Apoptosis, FLT, c-RET, TAM Receptor, Aurora Kinase
FLT3-IN-3
Cat.No: T11298
Synonym:
Target: FLT
AC1NS4RE
Cat.No: T2340
Synonym:
Target: Tyrosinase
TAK-659 hydrochloride
Cat.No: T4209
Synonym: TAK-659
Target: VEGFR, FLT, Tyrosine Kinases, JAK, Syk
FLT3-IN-2
Cat.No: T1938
Synonym:
Target: FLT
CCT241736
Cat.No: T4428
Synonym:
Target: FLT, Aurora Kinase
FN-1501
Cat.No: T15335
Synonym:
Target: FLT, CDK
AMG 925
Cat.No: T6756
Synonym:
Target: FLT, CDK
Fostamatinib
Cat.No: T6115
Synonym: R788,福他替尼
Target: FLT, Syk, Monoamine Transporter, Adenosine Receptor
Pacritinib
Cat.No: T6020
Synonym: SB1518
Target: FLT, Tyrosine Kinases, JAK
TG101209
Cat.No: T3065
Synonym:
Target: Apoptosis, FLT, c-RET, JAK, Autophagy
R406
Cat.No: T6174
Synonym: R-406 besylate
Target: Apoptosis, FLT, Syk
BPR1J-097
Cat.No: T2272
Synonym: BPR1J097
Target: FLT
TCS 359
Cat.No: T6138
Synonym: FLT3 Inhibitor
Target: FLT
ATH686
Cat.No: T7673
Synonym: ATH 686
Target: Apoptosis, FLT
CHIR-124
Cat.No: T6350
Synonym: CHIR124,CHIR 124
Target: Apoptosis, GSK-3, FLT, Chk, PDGFR, Src
R406 free base
Cat.No: T2467
Synonym: R406 (free base)
Target: Apoptosis, FLT, Syk
KW-2449
Cat.No: T2341
Synonym: KW2449
Target: Apoptosis, FGFR, FLT, JAK, Bcr-Abl, Src, c-Kit, Aurora Kinase
Merestinib
Cat.No: T3455
Synonym: LY2801653
Target: Discoidin Domain Receptor (DDR), FLT, c-Met/HGFR, ROS, ROS Kinase
4SC-203
Cat.No: T9473
Synonym:
Target: FLT
AT9283
Cat.No: T3068
Synonym: J-504568
Target: Apoptosis, FLT, JAK, Bcr-Abl, Aurora Kinase, Autophagy
AC710
Cat.No: TQ0235
Synonym:
Target: FLT, PDGFR, c-Kit
CA-4948
Cat.No: T9027
Synonym: Emavusertib
Target: IRAK, FLT
Gandotinib
Cat.No: T2638
Synonym: LY2784544
Target: VEGFR, FGFR, FLT, JAK
Rebastinib
Cat.No: T2640
Synonym: DCC2036,DCC 2036,DCC-2036
Target: Apoptosis, FLT, Bcr-Abl, Src
AKN-028
Cat.No: T38562
Synonym:
Target: FLT
Gilteritinib
Cat.No: T4409
Synonym: 吉列替尼,ASP2215
Target: FLT, TAM Receptor, c-Kit
MRX-2843
Cat.No: T16144
Synonym: UNC2371
Target: Others, FLT
Altiratinib
Cat.No: T2054
Synonym: DCC-2701
Target: VEGFR, Tie-2, FLT, Trk receptor, c-Met/HGFR
UNC2025
Cat.No: T7007
Synonym: mrx-6313,UNC-2025,UNC 2025
Target: FLT, TAM Receptor
ENMD-2076
Cat.No: T2358
Synonym:
Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase
Sorafenib
Cat.No: T0093L
Synonym: 索拉非尼,Bay 43-9006
Target: Apoptosis, Raf, VEGFR, FLT, Ferroptosis, PDGFR, c-Kit, Autophagy
AZD2932
Cat.No: T1836
Synonym:
Target: VEGFR, FLT, PDGFR, c-Kit
Fostamatinib Disodium
Cat.No: T2605
Synonym: Tamatinib Fosdium,福他替尼二钠盐,R788(Disodium),R788 Disodium,R788 (Fostamatinib) Disodium
Target: FLT, Syk
Crenolanib
Cat.No: T2677
Synonym: ARO 002,CP-868596
Target: FLT, PDGFR, Autophagy
KG5
Cat.No: T41003
Synonym:
Target: Raf, FLT, PDGFR, c-Kit
Sorafenib tosylate
Cat.No: T0093
Synonym: 甲苯磺酸索拉非尼,Bay 43-9006
Target: Apoptosis, Raf, VEGFR, FLT, Ferroptosis, PDGFR, c-Kit, Autophagy
Ripretinib
Cat.No: T8482
Synonym: DCC-2618,瑞普替尼
Target: Apoptosis, VEGFR, FLT, PDGFR, c-Kit
AST 487
Cat.No: T4053
Synonym: NVP-AST 487
Target: VEGFR, FLT, c-RET, Bcr-Abl, c-Kit
SKLB4771
Cat.No: T2051
Synonym: FLT3-​IN-​1,FLT3-IN-1
Target: FLT
Sitravatinib
Cat.No: T4349
Synonym: MG516,MGCD516
Target: Discoidin Domain Receptor (DDR), VEGFR, FLT, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor
(E/Z)-Zotiraciclib
Cat.No: T21503
Synonym: (E/Z)-TG02,(E/Z)-SB1317
Target: FLT, JAK, CDK
Quizartinib
Cat.No: T2066
Synonym: AC220,奎扎替尼
Target: Apoptosis, FLT, Autophagy, Ligands for Target Protein for PROTAC
Amuvatinib
Cat.No: T2516
Synonym: MP470,HPK 56
Target: Apoptosis, FLT, c-Met/HGFR, c-RET, DNA/RNA Synthesis, PDGFR, c-Kit
PF 477736
Cat.No: T6028
Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736
Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase
Dovitinib lactate hydrate
Cat.No: T6479
Synonym: Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Tyrphostin AG1296
Cat.No: T6711
Synonym: Tyrphostin AG 1296,AG 1296
Target: Apoptosis, FGFR, FLT, PDGFR, c-Kit
Dovitinib
Cat.No: T6289
Synonym: TKI258,多韦替尼,CHIR-258,度维替尼
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Linifanib
Cat.No: T2514
Synonym: 利尼伐尼,ABT-869,RG3635,AL-39324
Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy
Tandutinib
Cat.No: T1667
Synonym: MLN518,CT53518,NSC726292,坦度替尼
Target: Apoptosis, FLT, CSF-1R, PDGFR, Src, c-Kit
Cat. No. Product Name Target Signaling Pathways
T6S0033 Crotonoside

巴豆苷;异鸟苷,巴豆苷,Isoguanosine,2-HYDROXYADENOSINE

Others; FLT; HDAC Angiogenesis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others; Tyrosine Kinase/Adaptors
Crotonoside (Isoguanosine) 是从中草药巴豆中分离出来的一种天然产物。 它抑制 FLT3 和 HDAC3/6,有治疗急性髓性白血病 (AML)的研究潜力。

天然产物

Crotonoside
Cat.No: T6S0033
Synonym: 巴豆苷;异鸟苷,巴豆苷,Isoguanosine,2-HYDROXYADENOSINE
Target: Others, FLT, HDAC
Cat. No. Product Name Species Expression System
TMPY-06986 FGF-8b Protein, Human, Recombinant

NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-00132 Mesothelin Protein, Human, Recombinant

MPF,SMRP,Mesothelin

Human HEK293 Cells
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His)

MER6,CD47 molecule,IAP,OA3

Human HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc)

Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2

Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated

CD47 molecule,MER6,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His)

AITR,GITR-D,tumor necrosis factor receptor superfamily, memb...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPY-04683 CD47 Protein, Human, Recombinant

MER6,CD47 molecule,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His)

NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2

Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-01897 PRSS3 Protein, Human, Recombinant (His)

PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M...

Human HEK293 Cells
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His)

PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto...

Human HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re...

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His)

L-CA,T200,LCA,B220,protein tyrosine phosphatase, re...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-01180 CD86 Protein, Human, Recombinant (His)

CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72

Human HEK293 Cells
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece...

Human HEK293 Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPY-00357 HNT/NTM Protein, Human, Recombinant (His)

HNT,NTRI,IGLON2,neurotrimin

Human HEK293 Cells
HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
TMPY-04298 CDCP1 Protein, Human, Recombinant (His)

TRASK,CD318,CUB domain containing protein 1,SIMA1

Human HEK293 Cells
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-00480 NCAM1 Protein, Human, Recombinant (His)

neural cell adhesion molecule 1,CD56,MSK39,NCAM

Human HEK293 Cells
NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPY-03621 EphB2 Protein, Mouse, Recombinant (hFc)

Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,Prkm5,Sek<...

Mouse HEK293 Cells
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3.
TMPY-01268 SMYD3 Protein, Human, Recombinant (GST)

SET and MYND domain containing 3,ZMYND1,KMT3

Human Baculovirus Insect Cells
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg...
TMPY-03149 CDCP1 Protein, Human, Recombinant (mFc)

TRASK,SIMA135,CD318,CUB domain containing ...

Human HEK293 Cells
CDCP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.4 kDa and the accession number is Q9H5V8-3.
TMPY-04386 EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)

PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,...

Human Baculovirus Insect Cells
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPK-00447 CD45 Protein, Human, Recombinant (aa 26-577, hFc)

CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC 3....

Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (aa 26-577...
TMPJ-01288 KLF6 Protein, Human, Recombinant

CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...

Human E. coli
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul...
TMPY-00276 PLGF/PGF Protein, Human, Recombinant (mFc)

placental growth factor,D12S1900,PLGF,SHGC-10760,PGFL,PlGF-2

Human HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3.
TMPY-04015 COL9A1 Protein, Human, Recombinant (mFc)

DJ149L1.1.2,STL4,collagen, type IX, alpha 1,MED,EDM6,collage...

Human HEK293 Cells
COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3.
TMPY-06411 GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated

CD357,GITR-D,tumor necrosis factor receptor superfa...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3.
TMPY-05514 RANK/TNFRSF11A Protein, Human, Recombinant (mFc)

OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor superfamil...

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3.
TMPY-03960 COL9A1 Protein, Human, Recombinant (His)

EDM6,collagen, type IX, α1,STL4,collagen, type IX, alpha 1,M...

Human HEK293 Cells
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3.
TMPK-00398 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)

Fibroblast growth factor receptor 2,CD332,...

Human HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPK-00401 FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD...

Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
TMPJ-00391 FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)

FGF R2b,KGFR,BFR-1,FGFR2 β,FGFR2b,FGFR2,FGFR2 beta,CD3

Human HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
TMPY-04216 EphB2 Protein, Mouse, Recombinant (His)

Drt,Nuk,Qek5,Tyro5,Prkm5,Sek3,ETECK,Cek5,Hek5,EPH r...

Mouse HEK293 Cells
EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is P54763-3.
TMPY-00715 CD84 Protein, Human, Recombinant (His)

LY9B,mCD84,CD84 molecule,hCD84,SLAMF5

Human HEK293 Cells
CD84 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9UIB8-3.
TMPY-03883 CD47 Protein, Human, Recombinant (hFc)

OA3,CD47 molecule,IAP,MER6

Human HEK293 Cells
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q08722-3.
TMPY-02573 IL-17RC Protein, Human, Recombinant (aa 1-454, His)

IL17RL,interleukin 17 receptor C,IL17-RL,UNQ6118/PRO20040/PR...

Human Baculovirus Insect Cells
IL-17RC Protein, Human, Recombinant (aa 1-454, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is Q8NAC3-3.
TMPY-01656 VEGF183 Protein, Human, Recombinant

血管内皮生长因子,VEGF165,VPF,VEGF,vascular endothelial growth factor...

Human Baculovirus Insect Cells
VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3.
TMPY-03969 SUSD4 Protein, Human, Recombinant (mFc)

sushi domain containing 4,PRO222

Human HEK293 Cells
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical path...
TMPJ-00465 PTP1C Protein, Human, Recombinant (His)

HCP,Hematopoietic Cell Protein-Tyrosine Phosphatase...

Human E. coli
Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against inter...
TMPY-01692 NETO1 Protein, Human, Recombinant (His)

neuropilin (NRP) and tolloid (TLL)-like 1,BCTL1,BTC...

Human HEK293 Cells
Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDARs in the postsynaptic density. The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Both NETO1 and NETO2 share an identical and unique domain structure thus repr...
TMPY-03705 VEGF164 Protein, Canine, Recombinant

血管内皮生长因子,vascular endothelial growth factor A

Canine HEK293 Cells
VEGF164 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9MYV3-3.
TMPY-05590 NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated

NCAM,MSK39,CD56,neural cell adhesion molecule 1

Human HEK293 Cells
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 67.9 kDa and the accession number is P13591-3.
TMPY-04157 RANK/TNFRSF11A Protein, Human, Recombinant (His)

ODFR,OFE,CD265,PDB2,RANK,tumor necrosis factor receptor supe...

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q9Y6Q6-3.
TMPK-00399 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated

Keratinocyte growth factor receptor,K-sam,BEK,FGFR2 β (IIIb)...

Human HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPK-00729 Siglec-6 Protein, Human, Recombinant (His & Avi)

SIGLEC6,OBBP1,CD327,CD33L1,CD...

Human HEK293 Cells
Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains.Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
TMPK-00400 FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Fibroblast growth factor receptor 2,KGFR,FGFR-2,KSAM,CD3...

Human HEK293 Cells
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.3 kDa and the accession number is P21802-3.
TMPJ-00390 FGFR2IIIb Protein, Human, Recombinant (hFc)

FGFR2,FGFR2 beta,FGFR2 β,FGFR2IIIb,KGFR,FGF R2b,BFR-1,FGFR2b...

Human HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession number is P21802-3.
TMPY-05246 CD86 Protein, Human, Recombinant (His), Biotinylated

CD28LG2,B70,B7.2,LAB72,CD86 antigen,B7-2

Human HEK293 Cells
CD86 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P42081-3.
TMPY-05602 GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated

AITR,GITR,tumor necrosis factor receptor superfamily, member...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 43.1 kDa and the accession number is Q9Y5U5-3.
TMPY-03435 NCKIPSD Protein, Human, Recombinant (GST)

NCK interacting protein with SH3 domain,WASLBP,SPIN...

Human E. coli
NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an important role in stress fiber formation. NCKIPSD gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding d...
TMPY-05383 NKp30/NCR3 Protein, Human, Recombinant (hFc)

DAAP-90L16.3,natural cytotoxicity triggering recept...

Human HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is O14931-3.
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重组蛋白

FGF-8b Protein, Human, Recombinant
Cat.No: TMPY-06986
Species: Human
Expression System: E. coli
Mesothelin Protein, Human, Recombinant
Cat.No: TMPY-00132
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His)
Cat.No: TMPY-04935
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03763
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05191
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His)
Cat.No: TMPY-00072
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant
Cat.No: TMPY-04683
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00892
Species: Human
Expression System: HEK293 Cells
PRSS3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01897
Species: Human
Expression System: HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01020
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04142
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His)
Cat.No: TMPY-05748
Species: Human
Expression System: HEK293 Cells
CD86 Protein, Human, Recombinant (His)
Cat.No: TMPY-01180
Species: Human
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-01099
Species: Human
Expression System: HEK293 Cells
HNT/NTM Protein, Human, Recombinant (His)
Cat.No: TMPY-00357
Species: Human
Expression System: HEK293 Cells
CDCP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04298
Species: Human
Expression System: HEK293 Cells
NCAM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00480
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03621
Species: Mouse
Expression System: HEK293 Cells
SMYD3 Protein, Human, Recombinant (GST)
Cat.No: TMPY-01268
Species: Human
Expression System: Baculovirus Insect Cells
CDCP1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03149
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
Cat.No: TMPY-04386
Species: Human
Expression System: Baculovirus Insect Cells
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
Cat.No: TMPK-00447
Species: Human
Expression System: HEK293 Cells
KLF6 Protein, Human, Recombinant
Cat.No: TMPJ-01288
Species: Human
Expression System: E. coli
PLGF/PGF Protein, Human, Recombinant (mFc)
Cat.No: TMPY-00276
Species: Human
Expression System: HEK293 Cells
COL9A1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04015
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06411
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05514
Species: Human
Expression System: HEK293 Cells
COL9A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03960
Species: Human
Expression System: HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
Cat.No: TMPK-00398
Species: Human
Expression System: HEK293 Cells
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00401
Species: Human
Expression System: HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
Cat.No: TMPJ-00391
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04216
Species: Mouse
Expression System: HEK293 Cells
CD84 Protein, Human, Recombinant (His)
Cat.No: TMPY-00715
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03883
Species: Human
Expression System: HEK293 Cells
IL-17RC Protein, Human, Recombinant (aa 1-454, His)
Cat.No: TMPY-02573
Species: Human
Expression System: Baculovirus Insect Cells
VEGF183 Protein, Human, Recombinant
Cat.No: TMPY-01656
Species: Human
Expression System: Baculovirus Insect Cells
SUSD4 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03969
Species: Human
Expression System: HEK293 Cells
PTP1C Protein, Human, Recombinant (His)
Cat.No: TMPJ-00465
Species: Human
Expression System: E. coli
NETO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01692
Species: Human
Expression System: HEK293 Cells
VEGF164 Protein, Canine, Recombinant
Cat.No: TMPY-03705
Species: Canine
Expression System: HEK293 Cells
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05590
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (His)
Cat.No: TMPY-04157
Species: Human
Expression System: HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
Cat.No: TMPK-00399
Species: Human
Expression System: HEK293 Cells
Siglec-6 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00729
Species: Human
Expression System: HEK293 Cells
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00400
Species: Human
Expression System: HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00390
Species: Human
Expression System: HEK293 Cells
CD86 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05246
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05602
Species: Human
Expression System: HEK293 Cells
NCKIPSD Protein, Human, Recombinant (GST)
Cat.No: TMPY-03435
Species: Human
Expression System: E. coli
NKp30/NCR3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05383
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
T19119 3-Hydroxy Midostaurin-D5

CGP52421-D5

Others Others
3-Hydroxy Midostaurin-D5 (CGP52421-D5) is a deuterium-labeled 3-Hydroxy Midostaurin which is a metabolite of PKC412. PKC412 effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation (IC50s: 132 nM and 9.8 μM in culture medium and plasma).

同位素标记化合物

3-Hydroxy Midostaurin-D5
Cat.No: T19119
Synonym: CGP52421-D5
Target: Others
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