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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0068 |
Fluphenazine dihydrochloride
氟奋乃静盐酸盐,Prolixin,盐酸氟奋乃静,Fluphenazine hydrochloride |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Fluphenazine dihydrochloride (Prolixin) 是一种多巴胺受体D1/D2抑制剂。 | |||
T7943 |
Fluphenazine decanoate
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Fluphenazine decanoate 是一种高度连续的多巴胺 D2受体阻滞剂,是一种长效吩噻嗪抗精神病药,用于精神分裂症的研究。 | |||
T0068L2 |
Fluphenazine free base
Siqualine,Fluphenazine,Fluorophenazine,Fluorphenazine,Triflumethazine,Fluorfenazine |
Others | Others |
Flufenazine is an antipsychotic drug. It is used to treat chronic mental illnesses such as schizophrenia. Flufenazine works by blocking postsynaptic dopamine D2 receptors in the limbic system, cortical system, and basal ganglia. This prevents the effects | |||
T11304 |
Fluphenazine enanthate
|
Others | Others |
Fluphenazine enanthate is a novel long-acting injectable (LAI) antipsychotic compound specifically designed for the treatment of schizophrenia. | |||
T0068L |
Fluphenazine Decanoate Dihydrochloride
|
Others | Others |
Fluphenazine Decanoate Dihydrochloride is an antipsychotic agent, it could block postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia. | |||
T36820 |
Fluphenazine-N-2-chloroethane (hydrochloride)
|
Others | Others |
Fluphenazine is a traditional antipsychotic compound that tightly binds the dopamine D2 receptor (Ki = 0.55 nM) and also reversibly inhibits calmodulin at micromolar concentrations. Fluphenazine-N-2-chloroethane is a derivative of fluphenazine that contains an alkylating chlorethylamine chain, which produces irreversible protein binding. It is a relatively selective, irreversible antagonist of D2 receptors both in vitro (IC50 = 100 nM) and in vivo, inactivating approximately 90% of D2 receptors ... | |||
T37150 |
ADTN hydrobromide
|
Others | Others |
ADTN hydrobromide (6,7-ADTN) is a dopamine receptor agonist (EC50s = 3.5 and 0.65 μM in rat striatal and nucleus accumbens homogenates, respectively). ADTN hydrobromide stimulates production of cAMP in rat striatal homogenates, a process that is reduced by 70% in the presence of the dopamine antagonist fluphenazine at a concentration of 1 μM. | |||
T85273 |
Gonadorelin acetate
|
Others | Others |
Gonadorelin, a gonadotropin-releasing hormone receptor (GNRHR; Ki= 13 nM in CHO cells expressing the human receptor) agonist and tropic hormone, effectively stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from rat anterior pituitary cultures at 0.1 μg doses. Additionally, it triggers LH release from bovine anterior pituitary cultures at a 1 μM concentration. In vivo, gonadorelin induces ovulation in rats pretreated with fluphenazine (ED50= 610.3 ng/kg). ... | |||
T36805 |
TPC2-A1-N
TPC2-A1-N |
Others | Others |
TPC2-A1-N is a novel, lipophilic, membrane permeable isoform-selective small molecule agonist of two-pore channel 2 (TPC2). TPC2-A1-N plays its role by mimicking the physiological actions of NAADP and PI(3,5)P2 through independent binding sites. TPC2-A1-N has inverse effects on key lysosomal activities and increases the pH in the lysosomal lumen in a TPC2-dependent manner[1]. |
Cat. No. | Product Name | Target | Signaling Pathways |
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TMIH-0241 |
Fluphenazine-d8 Dihydrochloride
|
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Fluphenazine-d8 Dihydrochloride 是 Fluphenazine Dihydrochloride 的氘代化合物。Fluphenazine Dihydrochloride 的 CAS 号为 146-56-5。Fluphenazine hydrochloride 是一种多巴胺受体D1/D2抑制剂。 |