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Search Results for " fluoxetine "
Targets Recommended: 5-HT Receptor Serotonin Transporter MRP Autophagy

12

抑制剂 & 化合物

1

化合物库

3

同位素标记化合物

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Cat. No. Product Name
L5100 含氟化合物库

574 compounds
574 个含氟化合物的独特集合,可用于高通量筛选和高内涵筛选;

化合物库

含氟化合物库
Cat.No: L5100
Compounds: 574
Cat. No. Product Name Target Signaling Pathways
T0450 Fluoxetine

氟西汀,LY-110140

5-HT Receptor; Serotonin Transporter; MRP; Autophagy Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Fluoxetine (LY-110140) 是一种高度特异性的血清素摄取抑制剂,是选择性 5-羟色胺 (5-HT) 再吸收抑制剂。Fluoxetine 具有抗抑郁活性。
T0450L Fluoxetine hydrochloride

Fluoxetine HCl,盐酸氟西汀,LY-110140,Lilly110140

5-HT Receptor; Serotonin Transporter; Autophagy Autophagy; GPCR/G Protein; Neuroscience
Fluoxetine hydrochloride (Lilly110140) 是一种高度特异性血清素摄取抑制剂。它被用作抗抑郁药,并且通常比传统的抗抑郁药具有更可接受的副作用特征。
T36952 N-Nitroso Fluoxetine

Others Others
N-Nitroso fluoxetine is a derivative of fluoxetine.1It is genotoxic toS. typhimuriumwhen used at concentrations ranging from 0.06 to 0.12 mg/ml.
T71389 Fluoxetine oxalate

Others Others
Fluoxetine oxalate is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.
T37474 meta-Fluoxetine (hydrochloride)

Others Others
meta-Fluoxetine (hydrochloride) 可用于生命科学领域的相关研究。其产品编号为 T37474,CAS号为 79088-29-2。
T71587 Fluoxetine succinate ester

Others Others
Fluoxetine succinate ester is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.
T21029 Norfluoxetine Hydrochloride

Norfluoxetine HCl,去甲氟西汀

Others Others
Norfluoxetine Hydrochloride (Norfluoxetine HCl) 是氟西汀的活性代谢物。氟西汀是一种抗抑郁药。
T71585 DB03417

Others Others
DB03417 is a compound listed in web page: https://go.drugbank.com/drugs/DB03417. DB03417 is a potential tryptase inhibitor.
T68141 Seganserin

5-HT Receptor GPCR/G Protein; Neuroscience
Seganserin 是一种非选择性5-羟色胺2-HT 受体拮抗剂,可逆转了氟西汀和喹帕嗪对黄体酮诱导的食欲亢进,抑郁和痛觉的抑制作用,逆转氟西汀和喹帕嗪诱导的抗抑郁和镇痛作用。
TP1992L M40 acetate(143896-17-7 free base)

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
M40 acetate(143896-17-7 free base) 是一种有效的、非选择性的甘丙肽受体拮抗剂(GAL1 和 GAL2 的 Ki 值分别为 1.82 和 5.1 nM),在体外抑制大鼠脑中甘丙肽 (1-29) 的结合 (IC50 = 3 - 15 nM)。减弱氟西汀的抗抑郁作用并阻止甘丙肽诱导的体内食物摄入。在剂量 > 100 nM 时,对外周 GAL2 受体也表现出较弱的部分激动剂活性。
T26184 Seproxetine HCl

(S)-Norfluoxetine hydrochloride,Seproxetine hydrochloride,(S)-Desmethylfluoxetine Hydrochloride

Others Others
Seproxetine HCl, a more active enantiomer of N-desmethyl metabolite fluoxetine, works by selectively inhibiting the serotonin uptake carrier.
TP1992 M40

Potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant effects of fluoxetine and blocks galanin-induced food intake in vivo. Also exhibits weak partial agonist activity at peripheral GAL2 receptors at doses > 100 nM.

化合物

Fluoxetine
Cat.No: T0450
Synonym: 氟西汀,LY-110140
Target: 5-HT Receptor, Serotonin Transporter, MRP, Autophagy
Fluoxetine hydrochloride
Cat.No: T0450L
Synonym: Fluoxetine HCl,盐酸氟西汀,LY-110140,Lilly110140
Target: 5-HT Receptor, Serotonin Transporter, Autophagy
N-Nitroso Fluoxetine
Cat.No: T36952
Synonym:
Target: Others
Fluoxetine oxalate
Cat.No: T71389
Synonym:
Target: Others
meta-Fluoxetine (hydrochloride)
Cat.No: T37474
Synonym:
Target: Others
Fluoxetine succinate ester
Cat.No: T71587
Synonym:
Target: Others
Norfluoxetine Hydrochloride
Cat.No: T21029
Synonym: Norfluoxetine HCl,去甲氟西汀
Target: Others
DB03417
Cat.No: T71585
Synonym:
Target: Others
Seganserin
Cat.No: T68141
Synonym:
Target: 5-HT Receptor
M40 acetate(143896-17-7 free base)
Cat.No: TP1992L
Synonym:
Target: Neuropeptide Y Receptor
Seproxetine HCl
Cat.No: T26184
Synonym: (S)-Norfluoxetine hydrochloride,Seproxetine hydrochloride,(S)-Desmethylfluoxetine Hydrochloride
Target: Others
M40
Cat.No: TP1992
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TMID-0253 (±)-Fluoxetine-d4 Oxalate

(±)-Fluoxetine-d4 Oxalate 是 (±)-Fluoxetine Oxalate 的氘代化合物。(±)-Fluoxetine Oxalate 的 CAS 号为 114414-02-7。
TMID-0217 Norfluoxetine-d5 Hydrochloride

Norfluoxetine-d5 Hydrochloride 是 Norfluoxetine Hydrochloride 的氘代化合物。Norfluoxetine Hydrochloride 的 CAS 号为 57226-68-3。Norfluoxetine Hydrochloride 是氟西汀的活性代谢物。氟西汀是一种抗抑郁药。
T71302 Norfluoxetine-d5 HCl

Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa...

同位素标记化合物

(±)-Fluoxetine-d4 Oxalate
Cat.No: TMID-0253
Synonym:
Target:
Norfluoxetine-d5 Hydrochloride
Cat.No: TMID-0217
Synonym:
Target:
Norfluoxetine-d5 HCl
Cat.No: T71302
Synonym:
Target:
TargetMol Loading
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