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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77455 |
Burosumab
KRN23 |
Others | Others |
Burosumab(KRN23) 是一种靶向成纤维细胞生长因子 23 (FGF23) 的人单克隆抗体,用于治疗皮肤骨骼低磷血症综合征(CSHS)和肿瘤诱导的骨软化症。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03294 |
FGF-23 Protein, Rat, Recombinant (His)
Fibroblast growth factor 23 |
Rat | P. pastoris (Yeast) |
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL. FGF-23 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.5 kDa and the accession number is Q8VI82. | |||
TMPH-03293 |
FGF-23 Protein, Rat, Recombinant (E. coli, His)
Fgf23,Fibroblast growth facto... |
Rat | E. coli |
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL. |