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Search Results for " fgf23 "
Targets Recommended: Others

3

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9720 T3Inh-1

Others Others
T3Inh-1 是一种有效的选择性 ppGalNAc-T3 抑制剂,IC50 为 7 µM。 T3Inh-1 可预防乳腺癌细胞。 T3Inh-1 降低组织细胞和小鼠中的 FGF23 激素水平,而不会引起任何毒副作用。
T61122 ZINC12409120

R-4584

ERK MAPK
ZINC12409120 (R-4584) 是一种具有选择性的 ERK 抑制剂。ZINC12409120 对ERK具有抑制作用,IC50 为 5.0 μM。ZINC12409120 通过干扰 FGF23:α-Klotho 的相互作用而抑制 ERK 活性。
T77455 Burosumab

KRN23

Others Others
Burosumab(KRN23) 是一种靶向成纤维细胞生长因子 23FGF23) 的人单克隆抗体,用于治疗皮肤骨骼低磷血症综合征(CSHS)和肿瘤诱导的骨软化症。

化合物

T3Inh-1
Cat.No: T9720
Synonym:
Target: Others
ZINC12409120
Cat.No: T61122
Synonym: R-4584
Target: ERK
Burosumab
Cat.No: T77455
Synonym: KRN23
Target: Others
Cat. No. Product Name Species Expression System
TMPH-03294 FGF-23 Protein, Rat, Recombinant (His)

Fibroblast growth factor 23,Fgf23

Rat P. pastoris (Yeast)
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL. FGF-23 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.5 kDa and the accession number is Q8VI82.
TMPH-03293 FGF-23 Protein, Rat, Recombinant (E. coli, His)

Fgf23,Fibroblast growth factor 23

Rat E. coli
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL.

重组蛋白

FGF-23 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03294
Species: Rat
Expression System: P. pastoris (Yeast)
FGF-23 Protein, Rat, Recombinant (E. coli, His)
Cat.No: TMPH-03293
Species: Rat
Expression System: E. coli
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