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Search Results for " fe-s cluster "
Targets Recommended: Apoptosis HSP Reactive Oxygen Species

2

抑制剂 & 化合物

6

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T6170 Elesclomol

伊利司莫,STA-4783

Apoptosis; HSP; Reactive Oxygen Species Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB
Elesclomol (STA-4783) 是一种氧化应激诱导剂,也是一种高度亲脂性的铜离子载体。Elesclomol 可以诱导肿瘤细胞凋亡,用于铜死亡相关研究。Elesclomol 还可以抑制 FDX1 介导的 Fe-S 簇生物合成。
T28821 SMR000071098

SMR-000071098,SMR 000071098

Others Others
SMR000071098 is an inhibitor of Fe-S cluster-dependent aconitase. SMR000071098 interacts with Suf proteins to inhibit iron-sulfur (Fe-S) cluster assembly.

化合物

Elesclomol
Cat.No: T6170
Synonym: 伊利司莫,STA-4783
Target: Apoptosis, HSP, Reactive Oxygen Species
SMR000071098
Cat.No: T28821
Synonym: SMR-000071098,SMR 000071098
Target: Others
Cat. No. Product Name Species Expression System
TMPH-00930 Anamorsin Protein, Human, Recombinant (His & SUMO)

CIAPIN1,Fe-S cluster as<...

Human E. coli
Anamorsin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa and the accession number is Q6FI81.
TMPH-03746 NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated

Fe/S biogenesis protein ...

ENT-Escherichia coli E. coli
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The predicted molecular weight is 68.8 kDa and the accession number is B1X760.
TMPH-03705 NfuA Protein, Vibrio vulnificus, Recombinant

nfuA,Fe/S biogenesis pro...

Vibrio vulnificus E. coli
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, Vibrio vulnificus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.0 kDa and the accession number is Q8DDU2.
TMPH-00621 NfuA Protein, E. coli, Recombinant (His)

Fe/S biogenesis protein ...

E. coli E. coli
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.1 kDa and the accession number is B1X760.
TMPY-02482 Aconitase 1 Protein, Human, Recombinant (His)

HEL60,IRP1,ACONS,aconitase 1, sol...

Human Baculovirus Insect Cells
Aconitase 1(ACO1) or IRP1 is one member of the aconitase family that contains a diverse group of iron-sulphur(Fe-S) isomerases and two types of iron regulatory protein. Aconitase exits in two forms: one is soluble and the other is mitochondrial. ACO1 is the soluble existing form, and the mitochondrial form is ACO2. Residues from all three N-terminal domains and the larger C-terminal domain contribute to the active site region. When the enzyme is activated, it gains an additional iron atom. ACO1 ...
TMPY-02375 acnB Protein, E. coli, Recombinant

yacI,yacJ

E. coli E. coli
Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to SoxRS-mediated activation, whereas acnB encodes the major aconitase that is synthesized earlier in the growth cycle than AcnA. It is concluded that AcnB is the major citric acid cycle enzyme. Aconitate hydratase 2 (acnB) catalyzes the isomerization of citrate to isocitrate via cis-a...

重组蛋白

Anamorsin Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00930
Species: Human
Expression System: E. coli
NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated
Cat.No: TMPH-03746
Species: ENT-Escherichia coli
Expression System: E. coli
NfuA Protein, Vibrio vulnificus, Recombinant
Cat.No: TMPH-03705
Species: Vibrio vulnificus
Expression System: E. coli
NfuA Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00621
Species: E. coli
Expression System: E. coli
Aconitase 1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02482
Species: Human
Expression System: Baculovirus Insect Cells
acnB Protein, E. coli, Recombinant
Cat.No: TMPY-02375
Species: E. coli
Expression System: E. coli
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