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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T73755 |
Farnesyl pyrophosphate
|
Others | Others |
Farnesyl pyrophosphate (Farnesyl diphosphate) 是一种由15个碳原子组成的异戊二烯类化合物,作为甲羟戊酸 (MVA) 途径的关键代谢中间体。它充当TRPM2 (TRP Channel) 的激动剂,通过激活并打开TRPM2通道,促使离子流入细胞。此外,Farnesyl pyrophosphate 在胆固醇合成、泛醌合成、蛋白质法尼基化修饰以及香叶基-香叶基焦磷酸 (GGPP) 合成过程中扮演着至关重要的底物角色。 | |||
T37775 |
Farnesyl Pyrophosphate ammonium salt
FPP ammonium,Farnesyl diphosphate ammonium,(E,E)-Farnesyl pyrophosphate ammonium |
Others | Others |
Farnesyl Pyrophosphate ammonium (Farnesyl diphosphate ammonium) 是 MVA 途径的代谢中间体,可作为新发现的危险信号触发急性细胞死亡,诱导中风神经元丢失。 | |||
T26469L |
A-176120 ammonium
A-176120 ammonium (185049-54-1 Free base) |
Others | Others |
A-176120 ammonium 是一种新型法尼基焦磷酸类似物,具有具有抗肿瘤和抗血管生成特性,抑制法呢基转移酶活性。 | |||
T35589 |
Geranyl pyrophosphate triammonium
|
Others | Others |
Geranyl pyrophosphate is an intermediate in the mevalonate pathway. It is formed from dimethylallyl pyrophosphate and isopentenyl pyrophosphate by geranyl pyrophosphate synthase. Geranyl pyrophosphate is used in the biosynthesis of farnesyl pyrophosphate , geranylgeranyl pyrophosphate , cholesterol, terpenes, and terpenoids. | |||
T35433 |
α-hydroxy Farnesyl Phosphonic Acid
|
Others | Others |
α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 μM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells. | |||
T26469 |
A-176120
|
Others | Others |
A-176120 is a potent farnesyl pyrophosphate (FPP) analogues, it selectively inhibits farnesyltransferase. It has anti-angiogenic potential and may reduce H-ras NIH3T3 tumour growth. | |||
T36863 |
Geranylgeranyl Pyrophosphate (ammonium salt)
Geranylgeranyl Pyrophosphate (ammonium salt),GGPP |
Others | Others |
Geranylgeranyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway derived directly from farnesyl pyrophosphate and used in the biosynthesis of terpenes and terpenoids.[1] It is also serves as a substrate in the prenylation of a variety of critical intracellular proteins including small GTPases.[2] This post-translational modification is necessary for correct localization of proteins to intracellular membranes for proper functionality and has become a focus of anticancer drug disco... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02654 |
FDPS Protein, Human, Recombinant (His)
FPS,FPPS,Farnesyl pyrophosphate synthase |
Human | E. coli |
FDPS Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 42.4 kDa and the accession number is P14324-2. | |||
TMPH-01323 |
FDPS Protein, Human, Recombinant (His & SUMO)
(2E,6E)-farnesyl diphosphate synthase,Dimethylallyl... |
Human | E. coli |
FDPS Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 64.3 kDa and the accession number is P14324. |