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Search Results for " fr901379 "
Targets Recommended: Others

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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T35700 FR901379

Others Others
FR901379 is an echinocandin-like antifungal lipopeptide.1 It is active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR901379 is protective against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of pulmonary cysts and trophozoites in a mouse model of P. carinii infection. |1. Fujie, A., Iwamoto, T., Sato, B., et al. FR131535, a novel water-soluble echinocandin-like lipopeptide: Synthesis and bi...
T36024 FR179642 (hydrate)

FR179642 (hydrate)

Others Others
FR179642 is the cyclic peptide nucleus of the lipopeptide antifungal FR901379 and an intermediate in the synthesis of the echinocandin antifungal FK463 .1,2 1.Tomishima, M., Ohki, H., Yamada, A., et al.FK463, a novel water-soluble echinocandin lipopeptide: Synthesis and antifungal activityJ. Antibiot. (Tokyo)52(7)674-676(1999) 2.Ueda, S., Shibata, T., Ito, K., et al.Cloning and expression of the FR901379 acylase gene from Streptomyces sp. no. 6907J. Antibiot. (Tokyo)64(2)169-175(2011)

化合物

FR901379
Cat.No: T35700
Synonym:
Target: Others
FR179642 (hydrate)
Cat.No: T36024
Synonym: FR179642 (hydrate)
Target: Others
Cat. No. Product Name Target Signaling Pathways
T39148 FR179642

FR179642

Others Others
FR179642 is an essential intermediate compound utilized in the synthesis of Micafungin, an antifungal drug belonging to the echinocandin class. It serves as the cyclic peptide foundation for the structurally similar antifungal lipopeptide FR901379.

天然产物

FR179642
Cat.No: T39148
Synonym: FR179642
Target: Others
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