搜索结果

Search Results for " foxm1 "

Targets Recommended: Others

抑制剂 & 化合物

天然产物

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T73172	FOXM1-IN-1	Others	Others
	FOXM1-IN-1 是一种有效的 FOXM1抑制剂，IC50值为 2.65 µM。FOXM1-IN-1 显示出抗增殖活性。FOXM1-IN-1 降低FOXM1、PLK1、CDC25B 蛋白的表达。
T82374	FOXM1-IN-2	Others	Others
	FOXM1-IN-2是抗肿瘤活性的FOXM1抑制剂。
T4005	FDI-6 FDI6,FDI 6	Others	Others
	FDI-6 是FOXM1抑制剂。它能够作用于 MCF-7 乳腺癌细胞中，直接与 FOXM1 蛋白结合，从靶基因组中取代 FOXM1，并诱导随后的转录下调。
T16725	RCM-1	Others	Others
	RCM-1 是forkhead box M1 抑制剂，在 U2OS 细胞中的EC50为 0.72 μM。它能够阻止核定位，并促使FOXM1的蛋白酶体降解。它可用于研究哮喘和其他慢性气道疾病。
T74710	YX-2-107	CDK; PROTACs	Cell Cycle/Checkpoint; PROTAC
	YX-2-107 是一种具有选择性和高效性的降解 CDK6 的 PROTAC ，IC50 值为 4.4 nM。YX-2-107 在体外对 RB 磷酸化和 FOXM1 表达有抑制作用，对大鼠体内 Ph+ ALL 的发展有抑制作用。YX-2-107 可用于预防和治疗 Ph 染色体阳性 (Ph+) 急性淋巴细胞白血病 (ALL)。
T12917	Siomycin A	Others	Others
	Siomycin A is a thiopeptide antibiotic and is a selective inhibitor of Forkhead box M1(FOXM1) without affecting other members of the Forkhead box family, has anti-tumor and promotes apoptosis.
T4134L	OTS514 OTS514 HCl,OTS514 Hydrochloride,OTS-514,OTS 514	Apoptosis; TOPK	Apoptosis; MAPK
	OTS514 (OTS514 Hydrochloride) 是一种高效的 TOPK 抑制剂，IC50为 2.6 nM。它强效抑制 TOPK 阳性的肿瘤细胞生长，还可诱导细胞周期停滞和凋亡。

化合物

Synonym: FDI6,FDI 6

Target: CDK, PROTACs

Synonym: OTS514 HCl,OTS514 Hydrochloride,OTS-514,OTS 514

Target: Apoptosis, TOPK

Cat. No.	Product Name	Target	Signaling Pathways
T1679	Thiostrepton Thiactin,Bryamycin,Alaninamide,硫链丝菌素	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Thiostrepton (Alaninamide) 是一种选择性抑制FOXM1的抗生素。FOXM1会与 YAP/TEAD 复合物结合，形成YAP/TEAD/FOXM1 复合物。

天然产物

Thiostrepton

Cat.No: T1679

Synonym: Thiactin,Bryamycin,Alaninamide,硫链丝菌素

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01350	FOxM1 Protein, Human, Recombinant (GST) M-phase phosphoprotein 2,Hepatocyte nuclear factor 3 forkhea...	Human	E. coli
	Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response. FOxM1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 43.8 kDa and the accession number is Q08050.
TMPH-01351	FOxM1 Protein, Human, Recombinant (His & Myc & SUMO) Forkhead-related protein FKHL16,MPM-2 reactive phos...	Human	E. coli
	Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response. FOxM1 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is Q08050.