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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6170 |
Elesclomol
伊利司莫,STA-4783 |
Apoptosis; HSP; Reactive Oxygen Species | Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB |
Elesclomol (STA-4783) 是一种氧化应激诱导剂,也是一种高度亲脂性的铜离子载体。Elesclomol 可以诱导肿瘤细胞凋亡,用于铜死亡相关研究。Elesclomol 还可以抑制 FDX1 介导的 Fe-S 簇生物合成。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00220 |
Adrenodoxin, mitochondrial Protein, Bovine, Recombinant (His)
Hepato-ferredoxin,FDX1,Ferredoxin-1 |
Bovine | E. coli |
Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage to produce pregnenolone, the precursor of most steroid hormones. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. Adrenodoxin, mitochondrial Protein, Bov... |