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Targets Recommended: PROTACs

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Cat. No. Product Name Target Signaling Pathways
T41164 FC 11

PROTACs PROTAC
FC 11 is a highly potent focal adhesion Ki nase (FAK) PROTAC®Degrader (DC50 values are 40 to 370 pM depending on cell line), which is composed of the FAK inhibitor PF 562217 joined by a linker to the cereblon-binding ligand Pomalidomide. The effects of FC 11 are reversible upon compound wash out. FC 11 also degrades autophosphorylated FAK (pFAKtyr397), displaying near complete degradation after 3 hours at 100 nM in TM3 cells.
T84314 BFC1108

Apoptosis Apoptosis
BFC1108 可靶向 Bcl-2 并将其转化为促凋亡蛋白,抑制Bcl-2高表达的三阴性乳腺癌异种移植物的生长,抑制乳腺癌肺转移,促使表达 Bcl-2 的癌症细胞凋亡。
T70821 FC11409B

Others Others
FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.

化合物

FC 11
Cat.No: T41164
Synonym:
Target: PROTACs
BFC1108
Cat.No: T84314
Synonym:
Target: Apoptosis
FC11409B
Cat.No: T70821
Synonym:
Target: Others
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