52
2
22
3
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76792 |
Sibrotuzumab
BIBH 1,Anti-Human FAP Recombinant Antibody |
Others | Others |
Sibrotuzumab (BIBH 1) 是一种靶向成纤维细胞激活蛋白 (FAP)的人源化 IgG1 单克隆抗体。Sibrotuzumab 可用于研究结直肠癌和非小细胞肺癌。 | |||
T82417 |
FAP Ligand 1
|
Others | Others |
FAPLigand 1(FL)为高亲和力小分子FAP配体,专用于将药物导向表达FAP的成纤维细胞,适用于癌症放射成像研究的靶向。 | |||
T74546 |
FAP-2286
|
Others | Others |
FAP-2286,一种与放射性核素螯合剂 DOTA 偶联的 FAP 结合肽大环化合物。FAP-2286 对人 FAP 蛋白具有强亲和力,Kd 为 1.1 nM。FAP-2286 具有抗肿瘤活性。FAP-2286 可用放射性核素标记,用于治疗及诊断。 | |||
T74402 |
FAP-PI3KI1
|
Others | Others |
FAP-PI3KI1 是一种成纤维细胞活化蛋白 (FAP) 靶向 PI3K 抑制剂,可选择性靶向表达 FAP 的人特发性肺纤维化 (IPF)细胞并有效抑制胶原蛋白合成,减少胶原蛋白沉积。 | |||
T78921 |
FAP-IN-1
|
Others | Others |
FAP-IN-1,一种FAP (成纤维细胞激活蛋白)抑制剂,具有3.3 nM的IC50值,适用于癌症研究。 | |||
T79917 |
FAP-IN-2
|
Others | Others |
FAP-IN-2,一种标记有99mTc的含异腈FAPI(成纤维细胞活化蛋白)抑制剂衍生物,适用于肿瘤显像。 | |||
T74547 |
FAP-2286 acetate
|
Others | Others |
FAP-2286 acetate,一种与成纤维细胞活化蛋白(FAP)结合的肽偶联物,可通过放射性核素标记进行诊断应用,并展现出抗肿瘤活性。 | |||
T78214 |
FAP-IN-2 TFA
|
Others | Others |
FAP-IN-2 TFA为99mTc标记的异腈类FAP抑制剂衍生物,适用于肿瘤显像。 | |||
T9855 |
BR102910
4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]- |
Others | Others |
BR102910 (4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-) 是一种选择性的成纤维细胞活化蛋白(FAP)的抑制剂。 | |||
T1629 |
Rifapentine
MDL473,Rifapentina,Rifapentinum,DL 473,利福喷丁,Priftin,Cyclopentylrifampicin |
DNA/RNA Synthesis; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Rifapentine (Rifapentinum) 是可用于肺结核的抗生素。 | |||
T5099 |
Gefapixant
RO 4926219,AF219,MK-7264 |
P2X Receptor | Membrane transporter/Ion channel; Neuroscience |
Gefapixant (AF219) 是一个 P2X3 受体拮抗剂,其对人同源重组 hP2X3 和 hP2X2/3 的 IC50值分别是约 30 和 100-250 nM。 | |||
T0767 |
Sulfapyridine
磺胺吡啶,Sulfidine,Sulfidin,2-Sulfapyridine |
Antibacterial; Antibiotic; Autophagy | Autophagy; Microbiology/Virology |
Sulfapyridine (2-Sulfapyridine) 是一种磺酰胺类抗生素,是 Sulfasalazine 的代谢产物。它抑制重组 P. carinii 二氢蝶呤合成酶,IC50为 0.18 μM。它具有抗菌,抗炎和抗风湿作用。 | |||
T13033 |
Sulfaproxiline
Sulfaproxyline,Sulphaproxyline,Sulfaproxylin,磺胺普罗林 |
Antibacterial | Microbiology/Virology |
Sulfaproxiline (Sulfaproxylin) 是磺胺类合成抗菌药。 | |||
T4567 |
Sulfaphenazole
Plisulfan,Raziosulfa,Depocid,磺胺苯吡唑,Depotsulfonamide |
P450; Antibacterial | Metabolism; Microbiology/Virology |
Sulfaphenazole (Plisulfan) 是一种 CYP2C9的特异性抑制剂,抑制 CYP2C9介导的亚油酸动脉粥样硬化和促炎症效应,增加 AP-1的氧化应激和激活。 | |||
T26235 |
Sulfaperin
磺胺培林,Methylsulfadiazin,Archisulfa,Chemiopen,Demosulfan,Anastaf,Isosulfamerazine |
Antibacterial | Microbiology/Virology |
Sulfaperin (Chemiopen) 是一种磺胺类抗菌剂。 | |||
T6482 |
Efaproxiral Sodium
乙丙昔罗钠,RSR13 sodium |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Efaproxiral Sodium (RSR13 sodium) 是血红蛋白 (Hb) 合成变构调节剂,能够减少血红蛋白氧 (O2) 的结合亲和力。 | |||
T11263 |
FAPI-2
|
Others | Others |
Fapi-2 is a fibroblast activated protein (FAP) inhibitor used in cancer research. | |||
T35852 |
FAPI-34
|
Others | Others |
FAPI-34, a fibroblast-activating protein (FAP) inhibitor, boasts advantageous pharmacokinetic and biochemical attributes. | |||
T82416 |
FAPI-2 TFA
|
Others | Others |
FAPI-2 TFA为一种针对成纤维细胞活化蛋白(FAP)的抑制剂,适用于癌症研究领域。 | |||
T62879 |
OncoFAP
|
Others | Others |
OncoFAP 是一种超高亲和力的成纤维细胞激活蛋白(FAP)配体,具有潜在的肿瘤靶向作用。 | |||
T69660 |
NOTA-FAPI-4
|
Others | Others |
NOTA-FAPI-4 is an analogue of FAPI-4 and a fibroblast activation protein (FAP) inhibitor. NOTA-FAPI-4 is useful in the diagnosis or treatment of a disease characterized by overexpression of fibroblast activation protein (FAP). NOTA-FAPI-4 can be used as a PET tracer for detection of diseases or disorders related to fibroblast activation protein. | |||
T39922 |
FAPI-46
|
Others | Others |
FAPI-46 is a quinoline-derived radiotracer that specifically targets fibroblast activation protein (FAP). It exhibits enhanced tumor uptake and extended accumulation in tumor tissues, rendering it suitable for diverse cancer imaging applications. | |||
T11264 |
FAPI-4
DOTA-fapi-04,FAPI 4 |
Others | Others |
FAPI-4 是一种成纤维细胞激活蛋白 (FAP) 抑制剂,是FAPI配体,在原发性肝癌肝细胞癌(HCC)的PET成像中显示出强烈的肝脏摄取作用,常用于 PET 成像,可用于研究癌症。 | |||
T63846 |
Gefapixant citrate
|
Others | Others |
Gefapixant citrate 是口服具有活力的 P2X3 受体 (P2X3R) 拮抗剂,能够作用于人同源重组 hP2X3 (IC50: ~30 nM)和 hP2X2/3 (IC50: 100-200 nM)。Gefapixant citrate 能够用于研究慢性咳嗽与膝骨关节炎。 | |||
T29860 |
Alfaprostol
|
Others | Others |
Alfaprostol is a bioactive chemical. | |||
T25221 |
Cefaparole
Cefaparol,Lilly 110264,Lilly-110264,Lilly110264,Cefaparolum |
Others | Others |
Cefaparole is an antibacterial compound and cell wall biosynthesis inhibitor. | |||
TMAZ-0325B |
Anti-MFAP3 Monoclonal Antibody-Biotin
|
||
Anti-MFAP3 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting MFAP3. Anti-MFAP3 Monoclonal Antibody-Biotin can be used FACS. | |||
TMAZ-0325A6 |
Anti-MFAP3 Monoclonal Antibody-AF647
|
||
Anti-MFAP3 Monoclonal Antibody-AF647 is a biotin-conjugated humanized rabbit antibody targeting MFAP3. Anti-MFAP3 Monoclonal Antibody-AF647 can be used FACS. | |||
T82502 |
Efaprinermin alfa
OMP-336B11 |
||
Efaprinermin alfa (OMP-336B11),一种人源化单克隆抗体,靶向TNFRSF18。该化合物为GITR配体-Fc融合蛋白。 | |||
T26331 |
Wofapyrin
Rheopyrine,Reopin G |
Others | Others |
Wofapyrin is an antipyretic and antiphlogistic. | |||
TMAZ-0325A5 |
Anti-MFAP3 Monoclonal Antibody-AF555
|
||
Anti-MFAP3 Monoclonal Antibody-AF555 is a biotin-conjugated humanized rabbit antibody targeting MFAP3. Anti-MFAP3 Monoclonal Antibody-AF555 can be used FACS. | |||
TMAZ-0325A4 |
Anti-MFAP3 Monoclonal Antibody-AF488
|
||
Anti-MFAP3 Monoclonal Antibody-AF488 is a biotin-conjugated humanized rabbit antibody targeting MFAP3. Anti-MFAP3 Monoclonal Antibody-AF488 can be used FACS. | |||
T21318 |
Efaproxiral
RSR13,Efaproxyn,RSR 13,RSR-13 |
Others | Others |
Efaproxiral is a synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity, increasing tumor | |||
T29330 |
25-Desacetylrifapentine
L14583,L-14583 |
Others | Others |
25-Desacetylrifapentine is the main metabolite of DL 473-IT in plasma. | |||
T78667 |
FAPI-74
|
Others | Others |
FAPI-74 是一种 PET(正电子发射断层扫描)示踪剂,参与早期 FAPI-PET 成像。FAPI-74 可用于研究癌症肿瘤和退行性疾病。 | |||
TMAZ-0325P |
Anti-MFAP3 Monoclonal Antibody-PE
|
||
Anti-MFAP3 Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting MFAP3. Anti-MFAP3 Monoclonal Antibody-PE can be used FACS. | |||
TMAZ-0325A |
Anti-MFAP3 Monoclonal Antibody-APC
|
||
Anti-MFAP3 Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting MFAP3. Anti-MFAP3 Monoclonal Antibody-APC can be used FACS. | |||
T7890 |
SP-13786
UAMC-1110,(S)-N-[2-(2-氰基-4,4-二氟-1-吡咯烷基)-2-氧代乙基]喹啉-4-甲酰胺 |
Others | Others |
SP-13786 (UAMC-1110) 是成纤维细胞活化蛋白 (FAP) 的抑制剂 (IC50 : 3.2 nM);还抑制脯氨酰寡肽酶 (PREP) ( IC50 : 1.8 μM)。 | |||
T21724L |
Fas C-Terminal Tripeptide Acetate
Fas C-Terminal Tripeptide Acetate (189109-90-8 free base) |
Others; Fatty Acid Synthase | Metabolism; Others |
Fas C-Terminal Tripeptide Acetate 显示出对 Fas/FAP-1 结合的抑制活性。 | |||
T74482 |
Suc-Gly-Pro-AMC
|
Others | Others |
Suc-Gly-Pro-AMC 是一种成纤维细胞活化蛋白 (FAP) 特异性底物。Suc-Gly-Pro-AMC 可用于研究 FAP 的活性。 | |||
T69603 |
BR103354
|
Others | Others |
BR103354 is a novel fibroblast activation protein (FAP) inhibitor with anti-diabetic and anti-steatotic effects. BR103354 inhibited FAP with an IC50 value of 14 nM, showing high selectivity against dipeptidyl peptidase (DPP)-related enzymes and prolyl oligopeptidase (PREP). BR103354 exhibited good pharmacokinetic properties as evidenced by oral bioavailability of 48.4% and minimal hERG inhibition. Single co-administration of BR103354 with hFGF21 reduced nonfasting blood glucose concentrations, i... | |||
T26658 |
ARI-3099 HCl
ARI-3099,ARI3099,ARI 3099 |
Others | Others |
ARI-3099 inhibits fibroblast activation protein, alpha (FAP). | |||
T10227 |
Ac-Gly-BoroPro
|
Others | Others |
Ac-Gly-BoroPro is a selective FAP inhibitor (Ki: 23 nM). | |||
T38406 |
L-Proline 4-methoxy-β-naphthylamide hydrochloride
H-Pro-4MβNA hydrochloride,L-Proline 4-methoxy-β-naphthylamide hydrochloride |
Others | Others |
L-Proline 4-methoxy-β-naphthylamide hydrochloride, also known as H-Pro-4MβNA hydrochloride, is a chemical compound utilized in the preparation of Fap-activated anti-tumor compounds. | |||
T74499 |
FSDD1I
|
Others | Others |
FSDD1I为白蛋白结合成纤维细胞活化蛋白(FAP)配体,可68Ga和177Lu标记,用于单光子发射计算机断层扫描(SPECT)成像。 | |||
T74498 |
FSDD0I
|
Others | Others |
FSDD0I为一种与白蛋白结合的成纤维细胞活化蛋白(FAP)配体,能够与68Ga和177Lu标记,用于单光子发射计算机断层扫描(SPECT)成像。 | |||
T77863 |
TAM558
|
Others; Drug-Linker Conjugates for ADC | Antibody-drug Conjugate/ADC Related; Others |
TAM558为OMTX705合成中的有效载荷组分。OMTX705是人源化抗FAP(成纤维细胞活化蛋白)抗体,与TAM470结合后展示出抗肿瘤活性。 | |||
T74648 |
TAM470
|
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
TAM470 是一种新型的细胞溶素,可抑制微管蛋白聚集和微管解聚。TAM470 可作为有效载荷分子用于合成 OMTX705,OMTX705 是一种具有抗肿瘤活性的FAP 靶向抗体偶联活性分子 (ADCs)。 | |||
T74500 |
FSDD3I
|
Others | Others |
FSDD3I 是一种配体,特别是针对白蛋白结合成纤维细胞活化蛋白 (FAP) 的。它能够以68Ga 和177Lu 进行标记,进而应用于单光子发射计算机断层扫描 (SPECT) 成像技术。 | |||
T78179 |
NH2-UAMC1110 TFA
|
Others | Others |
NH2-UAMC1110 TFA 是 UAMC1110 的一个衍生物,用于合成 FAPI-QS。UAMC1110 是成纤维细胞激活蛋白(FAP)的抑制剂,而 FAPI-QS 作为螯合剂,用于制备特异性高、剂量大的放射性示踪剂,适用于肿瘤的诊断与治疗。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4643 |
TFAP
N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide |
COX; Endogenous Metabolite | Immunology/Inflammation; Metabolism; Neuroscience |
TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) 是环氧酶 1 的一种选择性抑制剂,IC50值为 0.8 μM。 | |||
T19320 |
FAPy-adenine
|
Others | Others |
FAPy-adenine is an oxidized DNA base.Adenine is on the rise in the brains of people with Alzheimer's disease.Nucleoside oxidation is a biochemical marker for tumors, senescence and neurodegenerative diseases. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00923 |
FAP Protein, Mouse, Recombinant (His)
FAPα,FAPalpha,DPPIVA,APCE,SIMP,FAP |
Mouse | HEK293 Cells |
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells. FAP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 86.4 kDa and the accession number is P97321-1. | |||
TMPK-00373 |
FAP Protein, Human, Recombinant (hFc)
FAPA,SIMP,DPPIV,FAPα,FAP,Seprase,... |
Human | HEK293 Cells |
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells. FAP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 112.3 kDa and the accession number is Q12884-1. | |||
TMPK-01282 |
FAP Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
FAPα,DPPIVA,SIMP,APCE,DPPIV,Seprase,FAP, |
Cynomolgus | HEK293 Cells |
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital in the malignant behaviors of cancer cells. FAP Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 88 kDa and the accession number is A0A2K5VGF4. | |||
TMPY-02154 |
FAP Protein, Human, Recombinant (His)
fibroblast activation protein, alpha,Fibroblast Activation P... |
Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1. | |||
TMPY-04962 |
FAP Protein, Cynomolgus, Recombinant (His)
fibroblast activation protein, α,fibroblast activation prote... |
Cynomolgus | HEK293 Cells |
FAP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is A0A2K5VGF4. | |||
TMPY-04922 |
FAP Protein, Human, Recombinant (His), Biotinylated
DPPIV,Fibroblast Activation Protein alpha,DPPIVA,SIMP,Fibrob... |
Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1. | |||
TMPY-06915 |
FAP Protein, Human, Recombinant (His & Avi), Biotinylated
FAPA,Fapalpha,Fibroblast Activation Protei... |
Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 88.23 kDa and the accession number is Q12884-1. | |||
TMPY-06525 |
FAP Protein, Human, Recombinant (aa 27-760, His)
Fibroblast Activation Protein alpha,fibroblast activation pr... |
Human | Baculovirus Insect Cells |
FAP Protein, Human, Recombinant (aa 27-760, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 86.31 kDa and the accession number is Q12884-1. | |||
TMPH-02674 |
GFAP Protein, Mouse, Recombinant
Gfap,Glial fibrillary acidic protein |
Mouse | Baculovirus Insect Cells |
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. | |||
TMPH-02673 |
GFAP Protein, Mouse, Recombinant (His & SUMO)
Glial fibrillary acidic protein,Gfap |
Mouse | E. coli |
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. | |||
TMPK-00900 |
MFAP4 Protein, Human, Recombinant (His & Flag)
Microfibril-associated glycoprotein 4,Mfap4 |
Human | HEK293 Cells |
MFAP4 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 28.6 kDa and the accession number is P55083-1. | |||
TMPK-01217 |
MFAP5 Protein, Mouse, Recombinant (hFc)
MP25,AAT9,MAGP2,MAGP-2,MFAP-5 |
Mouse | HEK293 Cells |
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC. MFAP5 Protein,... | |||
TMPK-00477 |
MFAP4 Protein, Cynomolgus, Recombinant (His)
Microfibril-associated glycoprotein 4,Mfap4 |
Cynomolgus | HEK293 Cells |
MFAP4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 27.60 kDa and the accession number is A0A2K5TQS8. | |||
TMPY-04171 |
MFAP3 Protein, Human, Recombinant (hFc)
microfibrillar-associated protein 3 |
Human | HEK293 Cells |
MFAP3 (Microfibril Associated Protein 3) is a Protein Coding gene. The human gene encoding MFAP3 has a very simple structure, containing only two translated exons encoding a protein of 362 amino acids. The gene was found to be located on chromosome 5q32-q33.2, near the locus 5q21-q31 reported for the fibrillin gene, FBN2, which has been linked to congenital contractural arachnodactyly. MFAP3 is widely expressed in the placenta, urinary bladder, and other tissues. It does not appear to share homo... | |||
TMPY-03052 |
MFAP5 Protein, Human, Recombinant (His)
microfibrillar associated protein 5,MFAP-5,AAT9,MAG... |
Human | HEK293 Cells |
MFAP5 (Microfibril Associated Protein 5, also known as MAGP2) is a Protein Coding gene. MFAP5 is a component of the elastin-associated microfibrils. It belongs to the MFAP family. As a 25-kD microfibril-associated glycoprotein, MFAP5 is rich in serine and threonine residues. It stimulates the assembly of elastic fibers, a complex structure composed of a tropoelastin inner core and microfibril outer mantle comprising proteins such as fibrillins and microfibril-associated glycoproteins that guide ... | |||
TMPH-00465 |
GFAP Protein, Danio rerio, Recombinant (His & Myc & SUMO)
gfap,Glial fibrillary acidic protein |
Danio rerio (Zebrafish) | E. coli |
N/A. GFAP Protein, Danio rerio, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 71.2 kDa and the accession number is Q58EE9. | |||
TMPJ-00846 |
GFAP Protein, Human, Recombinant (His)
Glial Fibrillary Acidic Protein,GFAP |
Human | E. coli |
Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desm... | |||
TMPK-00957 |
MFAP5 Protein, Human, Recombinant (hFc)
MAGP2,AAT9,MAGP-2,MP25,MFAP-5 |
Human | HEK293 Cells |
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC. MFAP5 Protein,... | |||
TMPY-02949 |
AP2 Gamma/TFAP2C Protein, Human, Recombinant (His)
ERF1,hAP-2g,transcription factor AP-2 gamma (activating enha... |
Human | E. coli |
TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2C may be prognostic indicators for patients with breast tumors. TFAP2C gene has been tested fo... | |||
TMPJ-00566 |
MFAP4 Protein, Human, Recombinant (His)
Microfibril-associated glycoprotein 4 |
Human | HEK293 Cells |
Microfibril-associated glycoprotein 4(MFAP4) is a secreted protein and contains 1 fibrinogen C-terminal domain, similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collagen and carbohydrate. It is thought to be an extracellular matrix protein which is involved in calcium-dependent cell adhesion or intercellular interactions. The gene is located within the Smith-Magenis syndrome region. | |||
TMPK-01159 |
MFAP4 Protein, Mouse, Recombinant (His & Flag)
Mfap4,Microfibril-associated glycoprotein 4 |
Mouse | HEK293 Cells |
MFAP4 Protein, Mouse, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 28.7 kDa and the accession number is Q9D1H9-1. | |||
TMPH-03279 |
DPP4/CD26 Protein, Rat, Recombinant (His & SUMO)
Dpp4,Dipeptidyl peptidase IV,DPP IV,CD26,Dipeptidyl peptidas... |
Rat | E. coli |
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular ... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TMID-0123 |
Rifapentine-d9
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Rifapentine-d9 是 Rifapentine 的氘代化合物。Rifapentine 的 CAS 号为 61379-65-5。Rifapentine是可用于肺结核的抗生素。 | |||
TMIH-0250 |
Gefapixant-d3
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Gefapixant-d3 是 Gefapixant 的氘代化合物。Gefapixant 的 CAS 号为 1015787-98-0。Gefapixant 是一个 P2X3 受体拮抗剂,其对人同源重组 hP2X3 和 hP2X2/3 的 IC50值分别是约 30 和 100-250 nM。 | |||
T13034 |
Sulfapyridine-d4
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Others | Others |
Sulfapyridine D4 a deuterium labeled Sulfapyridine. Sulfapyridine is a agent of sulfonamide antibacterial. |