Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T62385 |
Befiradol hydrochloride
NLX-112 hydrochloride,F 13640 hydrochloride |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Befiradol hydrochloride (NLX-112 hydrochloride) 是一种具有选择性的5-羟色胺 1A (5-HT)1A 受体激动剂,具有抗焦虑活性。Befiradol hydrochloride 抑制突变ATXN3聚集。 | |||
T69937 |
INCB059872 tosylate
|
Others | Others |
INCB059872, also known as INCB59872, is a potent, selective, and orally active lysine-specific demethylase 1 inhibitor. INCB059872 binds to and inhibits LSD1, a demethylase that suppresses the expression of target genes by converting the di- and mono-methylated forms of lysine at position 4 of histone H3 (H3K4) to mono- and unmethylated H3K4, respectively, through amine oxidation. LSD1 inhibition enhances H3K4 methylation and increases the expression of tumor-suppressor genes. In addition, LSD... | |||
T10495L |
Befiradol
NLX-112,F13640 |
Others | Others |
Befiradol (NLX-112) is an agonist of 5-HT1A receptor. |