Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03011 |
EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)
Low molecular weight protein antigen 7,esxH |
Mycobacterium tuberculosis | E. coli |
EsxH, in complex with EsxG, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery. |