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Cat. No. | Product Name | Target | Signaling Pathways |
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T37005 |
Estriol 3-β-D-Glucuronide (sodium salt)
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Others | Others |
Estriol 3-β-D-glucuronide is a metabolite of estriol . It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-β-D-glucuronide binds to basolateral and canalicular liver plasma membranes with Kd values of 85 and 164 μM, respectively. It competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide and is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc). | |||
T124799 |
Estriol 3-sulfate
|
Others | Others |
Estriol 3-sulfate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124799。 | |||
T126484 |
Estriol 3,17-dihexanoate
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Others | Others |
Estriol 3,17-dihexanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126484。 | |||
T124856 |
Estriol 17-sulfate
|
Others | Others |
Estriol 17-sulfate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124856。 | |||
T73761 |
Estriol 16α-(β-D-glucuronide)
|
Others | Others |
Estriol 16α-(β-D-glucuronide) 是存在于尿中的内源代谢物,可用于研究妊娠。 | |||
T20744 |
Nylestriol
Nilestriolum,Lilly 49825,尼尔雌醇,LY 49825,LY-49825,LY49825 |
Estrogen Receptor/ERR | Endocrinology/Hormones |
Nylestriol (LY 49825) 是雌激素受体的激动剂。 | |||
T36913 |
17-Epiestriol
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Others | Others |
17-Epiestriol is a metabolite of estrone .1It is formed from estroneviaa 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding affinities of 29 and 80 compared with 17β-estradiol .2 1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Kuiper, G.G.J.M., Lemme... | |||
T33545 |
Mytatrienediol
SC6924,SC 6924,Anvene,SC-6924,Manvene |
Others | Others |
Mytatrienediol is a synthetic, steroidal, weak estrogen and estrogen ether derived from estriol. | |||
T36920 |
16α-hydroxy Dehydroepiandrosterone
|
Others | Others |
16α-hydroxy Dehydroepiandrosterone is a metabolite of the endogenous steroid hormone dehydroepiandrosterone .116α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosteronevia16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol .2 1.Miller, K.K.M., Cai, J., Ripp, S.L., et al.Stereo- and regioselectivity account for the diversity of dehydro... | |||
T36039 |
16α-Hydroxyestrone
|
Others | Others |
The naturally-occurring estrogens are estrone , estradiol , and estriol . 16α-hydroxy Estrone (16α-OHE1) is a hydroxylated metabolite of E1 as well as an interconversion product with E2. E1 is 16α-hydroxylated by cytochrome P450 (CYP) isoforms, including CYP1A1, CYP3A5, CYP3A4, and CYP3A7, with CYP3A5 being breast-specific. 16α-OHE1 is sulphatized or glucuronidated before excretion. It is increased in rheumatoid arthritis and decreased by physical activity. Unlike the parent estrogens and other ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1571 |
Estriol
NSC-12169,Oestriol,雌三醇 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; MRP; Endogenous Metabolite | Endocrinology/Hormones; Immunology/Inflammation; Metabolism |
Estriol (Oestriol) 是G 蛋白偶联雌激素受体拮抗剂,能够作用于雌激素受体阴性乳腺癌细胞。 | |||
T37499 |
Estriol 3-glucuronide
|
Others | Others |
Estriol-3-glucuronide, a natural compound found in urine, is also present in amniotic fluid during normal pregnancy [1][2]. | |||
T1683 |
Actriol
异雌三醇,Epiestriol |
Glucocorticoid Receptor | Endocrinology/Hormones |
Actriol (Epiestriol) 是内源性雌激素雌酮的代谢物,拥有抗炎及抗菌活性。 |
Cat. No. | Product Name | Species | Expression System |
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TMPH-02139 |
CYP17A1 Protein, Human, Recombinant (GST)
Cytochrome P450 17A1,CYPXVII,CYP17A1,CYP17,S17AH,Cytochrome ... |
Human | E. coli |
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol (Probable). Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, follow... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIJ-0280 |
Estriol-d3
|
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Estriol-d3 是 Estriol 的氘代化合物。Estriol 的 CAS 号为 50-27-1。Estriol 是G蛋白偶联雌激素受体拮抗剂,能够作用于雌激素受体阴性乳腺癌细胞。 | |||
TMIJ-0255 |
Estrone-d4
Estriol EP Impurity B-d4 |
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Estrone-d4 是 Estrone 的氘代化合物。Estrone 的 CAS 号为 53-16-7。Aquacrine是内源性雌激素的主要代表,由多种组织产生,尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。 | |||
TMIJ-0035 |
16α-Hydroxy-17β-estradiol-2,4-d2
|
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16α-Hydroxy-17β-estradiol-2,4-d2 是 Estriol 的氘代化合物。Estriol 的 CAS 号为 50-27-1。Estriol 是G蛋白偶联雌激素受体拮抗剂,能够作用于雌激素受体阴性乳腺癌细胞。 |