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Search Results for " escherichia coli "

Targets Recommended: Others DNA/RNA Synthesis Antibacterial

91

抑制剂 & 化合物

41

天然产物

9

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T14864	Caracemide NSC-253272,卡醋胺	Others; DNA/RNA Synthesis; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Caracemide (NSC-253272) 抑制大肠杆菌的核糖核苷酸还原酶。 Caracemide 可用于抗癌研究。
T33828	O-Succinylhomoserine O-琥珀酰-L-高丝氨酸,O-Succinyl-L-homoserine	Others	Others
	O-Succinylhomoserine (O-Succinyl-L-homoserine) 是大肠杆菌合成胱硫醚的中间体。
T36683	Vedaprofen Quadrisol,PM 150,维达洛芬,CERM 10202	COX; Antibacterial; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Vedaprofen (PM 150) 抑制 COX-1 并通过抗炎活性减少前列腺素 H2 的合成。 Vedaprofen 是一种大肠杆菌滑动钳抑制剂，IC50 为 222 μM，Ki 为 131 μM。
T1224	Cefuroxime sodium Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin	Antibacterial; Antibiotic	Microbiology/Virology
	Cefuroxime sodium (Cefuroxime sodium salt) 是一种具有口服活性的头孢菌素抗生素，增加了对 β-内酰胺酶的稳定性。
T0909L	Nalidixic acid sodium salt 萘啶酮酸,萘啶酮酸钠,Baktogram,Sodium nalidixate	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Nalidixic acid sodium salt (Baktogram) 是一种喹诺酮类抗生素，对革兰氏阳性和革兰氏阴性细菌均有效。它在较低浓度下有抑菌作用，在较高浓度下有杀菌作用。它抑制 DNA 促旋酶和拓扑异构酶IV 的亚基，并可逆地阻止易感细菌中的 DNA 复制。
T6179	Moxalactam sodium salt Latamoxef sodium,6059 S,拉氧头孢钠,Moxalactam Disodium,LY-127935,Antibiotic 6059S,Shiomarin,FestamoxinLy	Antibacterial; Antibiotic	Microbiology/Virology
	Moxalactam sodium salt (LY-127935) 是一种抗生素, 对大肠杆菌和绿脓杆菌有作用。
T0788L	Spectinomycin dihydrochloride pentahydrate 盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Spectinomycin dihydrochloride pentahydrate (Spectogard) 是一种广谱氨基环糊精抗生素，可以抑制多种革兰氏阳性和革兰氏阴性生物的生长。
T33470	Monoctanoin 辛酸2,3-二羟基酯,Glyceryl 1-caprylate,Moctanin	Antibacterial	Microbiology/Virology
	Monoctanoin (Glyceryl 1-caprylate) 对金黄色葡萄球菌和大肠杆菌具有抗菌活性。
T8629	N-BENZYL-2-PHENYLETHYLAMINE	Others	Others
	N-BENZYL-2-PHENYLETHYLAMINE 是 rel+ Escherichia coli B Phe-tRNA 的抑制剂。
T60093	CHEMBL1380345 N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)	Antibacterial	Microbiology/Virology
	CHEMBL1380345 对金黄色葡萄球菌、蜡状芽孢杆菌和大肠杆菌具有抗菌活性，pMIC 值分别为 3.64、3.56 和 3.70。
T38137	3,5-Dimethylbenzaldehyde	Endogenous Metabolite; Antifungal	Metabolism; Microbiology/Virology
	3,5-Dimethylbenzaldehyde 具有广谱的抗菌活性，对枯草芽孢杆菌、白假丝酵母菌、大肠杆菌、铜绿假单胞菌、金黄色葡萄杆菌和肺炎链球菌具有抑制作用。
T10347L	Apidaecin IB acetate Apidaecin IB acetate (123276-94-8 Free base)	Others	Others
	Apidaecin IB acetate 是一种昆虫抗菌肽。 apidaecin IB acetate 对大肠杆菌（大肠杆菌 ML35、o18k1h7 和 ATCC 25922）的有效浓度为 8 μM。
T67928	NDH-1 inhibitor-1	Mitochondrial Metabolism	Metabolism
	NDH-1 inhibitor-1 是一种有效的 NDH-1 抑制剂，对牛 SMP (线粒体颗粒)，马铃薯 SMP 和大肠杆菌的 pI50 值分别为 <4, 5.40, 6.15 µM。
T3175	LDHA-IN-4 AZ 33,AZ-33,LDHA Inhibitor,AZ33	Dehydrogenase	Metabolism
	LDHA-IN-4 (AZ33) 是乳酸脱氢酶 A 选择性抑制剂，IC50=0.5 μM，Kd=0.093 μM。
T41274	p-Fluoro-L-phenylalanine	Hydroxylase	Metabolism
	p-Fluoro-L-phenylalanine 是酪氨酸羟化酶的一种底物。它可以与大肠杆菌的 L-亮氨酸特异性受体结合，KD 为0.26 μM。
T36020	Florfenicol amine hydrochloride	Antibiotic	Microbiology/Virology
	Florfenicol amine hydrochloride 是一种人工合成的兽用抗生素，具有抗菌活性。Florfenicol amine hydrochloride 在水产养殖业和牧业养殖业中应用广泛，可以用来研究巴氏杆菌、爱德华氏菌、大肠杆菌和沙门氏杆菌引起的疾病。
T9727	2'-Fluoro-2'-Deoxyadenosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2′-Deoxy-2′-fluoroadenosine 可用于合成2 ' -脱氧-2 ' -氟修饰的寡核苷酸。它能被大肠杆菌嘌呤核苷磷酸化酶（PNP）有效地分解成毒性物 2-氟腺嘌呤，对表达大肠杆菌 PNP 的肿瘤表现出良好的体内活性。
T61042	TBT1	Antibacterial	Microbiology/Virology
	TBT1 是一种新型 MsbA 转运蛋白抑制剂，也是 MsbA ATPase 刺激剂，抑制脂多糖合成途径中ATP依赖性转运蛋白的合成。TBT1 具有抗菌活性，抑制沙门氏菌、铜绿假单胞菌、大肠杆菌和金黄色葡萄球菌，可用于研究细菌感染。
T77608	1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl-	Antifungal	Microbiology/Virology
	1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl- 可作为一种广谱抗菌剂，对黑曲霉枯草芽孢杆菌、白假丝酵母、大肠杆菌和金黄色葡萄球菌有抑制作用。1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl- 在体外实验中显示出抗炎活性，可用于治疗细菌感染。
T29919	Altronic acid	Others	Others
	Altronic acid comes from Escherichia coli.
T64135	Antibacterial agent 68	Others	Others
	Antibacterial agent 68 是一种针对耐药 Escherichia coli 的抗菌剂，具有低细胞毒性。Antibacterial agent 68 在 0.007 mM 的低浓度下能够强烈抑制多重耐药的 Escherichia coli 的活性。
T20751	Carumonam	Others	Others
	Carumonam, an antibiotic, could enhance the reactivity of Escherichia coli with mono- and polyclonal antisera to rough Escherichia coli J5.
T26579	AHU1	Others	Others
	AHU1 is a blocker of Shiga Toxin expression in Escherichia coli O157:H7.
T38567	STh
	STh, also known as Escherichia coli heat-stable toxin, is a 19 amino acid polypeptide containing three disulfide bridges. It serves as an antigen of significance in the quest for a comprehensive enterotoxigenic Escherichia coli (ETEC) vaccine.
T31475	Dihydropteroyl hexaglutamate	Others	Others
	Dihydropteroyl hexaglutamate is a link binding together sub-structures of the tail of Escherichia coli bacteriophage T4.
T71535	GlmU-IN-5175178	Others	Others
	GlmU-IN-5175178 is an inhibitor of the acetyltransferase activity of Escherichia coli N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU).
T25733	Lincophenicol	Others	Others
	Lincophenicol is an Escherichia coli ribosomal peptidyltransferase-catalyzed puromycin reaction inhibitor.
T69372	Cyclamidomycin	Others	Others
	Cyclamidomycin is an antibiotic. It also functions as an inhibitor of nucleoside diphosphokinase of Escherichia coli.
T80398	Brevinin-1PMa
	Brevinin-1PMa为宿主防御肽，对金黄色葡萄球菌（Staphylococcus aureus）和大肠杆菌（Escherichia coli）展现出抗菌活性，并具溶血活性。
T30826	Cgp 31523A Cgp-31523A,Cgp31523A	Others	Others
	CGP 31523a is a new type of aminothiazolyl cephalosporin, which can inhibit Escherichia coli, Klebsiella pneumoniae, Pseudomonas mirabilis, Clostridium diving, Klebsiella acidogenes, Pseudomonas Stuart, Salmonella, and Shigella.
T29882	Allolactose	Others	Others
	Allolactose is a disaccharide used as an inducer of the lac operon in Escherichia coli and many other enteric bacteria.
T80411	Bactenecin 5
	Bactenecin 5是一种具有抗菌活性的牛抗菌肽，能够针对Escherichia coli、Salmonella typhimurium和Klebsiella pneumoniae. T发挥作用，其最小抑菌浓度（MIC）介于12-25 μg/mL之间。
T10944	D13-9001	Others	Others
	The KD values of D13-9001 in Escherichia coli and Pseudomonas aeruginosa were 1.15μM and 3.57μM, respectively. D13-9001 has antibiotic activity. It is an effective AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor.
T80413	Bass hepcidin
	Bass hepcidin是一种具有针对大肠埃希菌活性的抗菌肽。
T28807	SLUPP-225 SLUPP 225	Others	Others
	SLUPP-225 is an efflux pump inhibitor (EPI) by interacting with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli.
T61368	FPI-1602	Others	Others
	FPI-1602 is a β-lactamase inhibitor with strong antimicrobial activity against Pseudomonas aeruginosa, Escherichia coli, and Enterobacter species [1].
T39296	DS86760016	Others	Others
	DS86760016 is a highly effective inhibitor of leucyl-tRNA synthetase (LeuRS), demonstrating potent activity against multidrug-resistant (MDR) Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Notably, DS86760016 effectively inhibits LeuRS enzymes derived from Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii, exhibiting IC50 values of 0.38 μM, 0.62 μM, and 0.16 μM, respectively.
T80323	Bovine neutrophil beta-defensin 12 BNBD-12
	Bovine neutrophil beta-defensin 12，一种牛中性粒细胞来源的抗菌肽，展现针对大肠杆菌(Escherichia coli)和金黄色葡萄球菌(Staphylococcus aureus)的抗菌活性。
T28808	SLUPP-417 SLUPP417	Others	Others
	SLUPP-417 is an efflux pump inhibitor (EPI) by interacting with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli.
T63449	MsbA-IN-3	Others	Others
	MsbA-IN-3 是一种有效的、高度选择性的 MsbA 抑制剂 (IC50: 2 nM)。MsbA-IN-3 能够抑制大肠杆菌 (Escherichia coli) 的活性 (MIC: 35 μM)。
T68203	Tuberine, (+)-	Others	Others
	Tuberine, (+)- is an alkaloid isolated from Haplophyllum tuberculatum that has high antimicrobial activity against Staphylococcus aureus, Bacillus subtilis and Saccharomyces cerevisiae. Tuberine, (+)- is also slightly inhibitory to Escherichia coli .
T77237	N,O-Didansyl-L-tyrosine cyclohexylammonium
	N,O-Didansyl-L-tyrosine cyclohexylammonium 是一种有效的选择性胸苷酸合成酶 (TS) 抑制剂，作用于Escherichia coli，Lactobacillus casei 和人的 TS 的IC50值分别是 5.0，3.4 和 119 μM。
T40433	D-Cystine	Others	Others
	D-Cystine, the D-enantiomer of L-Cystine, functions as an inhibitor of L-aspartate-β-semialdehyde dehydrogenase (ASADH) derived from Escherichia coli.
T63033	MsbA-IN-4	Others	Others
	MsbA-IN-4 (compound 32) 是一种高度选择性的、有效的 MsbA 抑制剂 (IC50: 3 nM)。MsbA-IN-4 能够抑制大肠杆菌 (Escherichia coli) (MIC: 12 μM)。
T80317	Combi-2
	Combi-2为针对S.aureus、S.sanguis及E.coli具有抗菌活性的肽类化合物。
T80447	Pardaxin P5
	Pardaxin P5，一种抗菌肽，其对大肠杆菌的最小抑制浓度（MIC）为13 μM。
T80339	Gallin
	Gallin是一种从蛋清提取的抗菌肽，在0.25 µM浓度时能够抑制Escherischia coli的生长。
T73531	SABA1	Others	Others
	SABA1 具有抗菌活性，比如铜绿假单胞菌和大肠杆菌，其对大肠杆菌的IC50值为 4.0 µM。
T68438	APO-6619	Others	Others
	APO-6619 is an iron chelator which was shown to inhibit growth of the following bacterial strains: Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, and Escherichia coli. APO-6619 may be useful as a non-traditional treatment of bacterial infections.
T81157	SIGSLAK
	SIGSLAK 拥有与大肠杆菌青霉素结合蛋白 1b (PBP1b) 活性位点相对应的结构特征。

化合物

Cat.No: T14864

Synonym: NSC-253272,卡醋胺

Target: Others, DNA/RNA Synthesis, Antibacterial

O-Succinylhomoserine

Cat.No: T33828

Synonym: O-琥珀酰-L-高丝氨酸,O-Succinyl-L-homoserine

Target: Others

Cat.No: T36683

Synonym: Quadrisol,PM 150,维达洛芬,CERM 10202

Target: COX, Antibacterial, Prostaglandin Receptor

Cefuroxime sodium

Cat.No: T1224

Synonym: Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin

Target: Antibacterial, Antibiotic

Nalidixic acid sodium salt

Cat.No: T0909L

Synonym: 萘啶酮酸,萘啶酮酸钠,Baktogram,Sodium nalidixate

Target: Topoisomerase, Antibacterial, Antibiotic

Moxalactam sodium salt

Cat.No: T6179

Synonym: Latamoxef sodium,6059 S,拉氧头孢钠,Moxalactam Disodium,LY-127935,Antibiotic 6059S,Shiomarin,FestamoxinLy

Target: Antibacterial, Antibiotic

Spectinomycin dihydrochloride pentahydrate

Cat.No: T0788L

Synonym: 盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate

Target: ribosome, Antibacterial, Antibiotic

Cat.No: T33470

Synonym: 辛酸2,3-二羟基酯,Glyceryl 1-caprylate,Moctanin

Target: Antibacterial

N-BENZYL-2-PHENYLETHYLAMINE

Cat.No: T8629

Target: Others

Cat.No: T60093

Synonym: N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)

Target: Antibacterial

3,5-Dimethylbenzaldehyde

Cat.No: T38137

Target: Endogenous Metabolite, Antifungal

Apidaecin IB acetate

Cat.No: T10347L

Synonym: Apidaecin IB acetate (123276-94-8 Free base)

Target: Others

NDH-1 inhibitor-1

Cat.No: T67928

Target: Mitochondrial Metabolism

Cat.No: T3175

Synonym: AZ 33,AZ-33,LDHA Inhibitor,AZ33

Target: Dehydrogenase

p-Fluoro-L-phenylalanine

Cat.No: T41274

Target: Hydroxylase

Florfenicol amine hydrochloride

Cat.No: T36020

Target: Antibiotic

2'-Fluoro-2'-Deoxyadenosine

Cat.No: T9727

Target: Nucleoside Antimetabolite/Analog

Cat.No: T61042

Target: Antibacterial

1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl-

Cat.No: T77608

Target: Antifungal

Cat.No: T29919

Target: Others

Antibacterial agent 68

Cat.No: T64135

Target: Others

Cat.No: T20751

Target: Others

Cat.No: T26579

Target: Others

Cat.No: T38567

Dihydropteroyl hexaglutamate

Cat.No: T31475

Target: Others

GlmU-IN-5175178

Cat.No: T71535

Target: Others

Cat.No: T25733

Target: Others

Cat.No: T69372

Target: Others

Cat.No: T80398

Cat.No: T30826

Synonym: Cgp-31523A,Cgp31523A

Target: Others

Cat.No: T29882

Target: Others

Cat.No: T80411

Cat.No: T10944

Target: Others

Cat.No: T80413

Cat.No: T28807

Synonym: SLUPP 225

Target: Others

Cat.No: T61368

Target: Others

Cat.No: T39296

Target: Others

Bovine neutrophil beta-defensin 12

Cat.No: T80323

Synonym: BNBD-12

Cat.No: T28808

Synonym: SLUPP417

Target: Others

Cat.No: T63449

Target: Others

Cat.No: T68203

Target: Others

N,O-Didansyl-L-tyrosine cyclohexylammonium

Cat.No: T77237

Cat.No: T40433

Target: Others

Cat.No: T63033

Target: Others

Cat.No: T80317

Cat.No: T80447

Cat.No: T80339

Cat.No: T73531

Target: Others

Cat.No: T68438

Target: Others

Cat.No: T81157

Cat. No.	Product Name	Target	Signaling Pathways
T2904	Sclareolide 香紫苏内酯,Norambreinolide	Others; Antibacterial	Microbiology/Virology; Others
	Sclareolide (Norambreinolide) 是一种从Salvia sclarea 的花中分离得到的天然产物，具有抗菌和细胞毒性作用。
T0909	Nalidixic acid 萘啶酸,NSC-82174	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Nalidixic acid (NSC-82174) 是一种喹诺酮类抗生素，对革兰氏阳性和革兰氏阴性细菌有效。它在较低浓度下有抑菌作用，而在较高浓度下有杀菌作用。它抑制 DNA 促旋酶和拓扑异构酶 IV 的亚基，并可逆地阻止易感细菌中的 DNA 复制。
T0788	Spectinomycin dihydrochloride 淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Spectinomycin dihydrochloride (Actinospectacin) 是一种能与细菌核糖体的30S 亚基结合，干扰蛋白质合成的抗生素。
T10941	D-Ribonolactone D-(+)-核糖酸-1,4-内酯,D-核糖内酯	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-Ribonolactone 是一种大肠杆菌 β-半乳糖苷酶的抑制剂，Ki 为 26 mM。它也一种糖内酯。
TF0083	POPE
	POPE 是从大肠杆菌中发现的化合物，是细胞膜的一部分，可用来研究改变细胞膜通透性。
T7565	3-Hydroxycapric acid	Endogenous Metabolite	Metabolism
	3-Hydroxycapric acid 是有丝分裂抑制剂。
T6S2116	Ginkgolic acid C17:1 银杏酸 C17:1,银杏酸C17:1	Phosphatase; PTEN	Metabolism; PI3K/Akt/mTOR signaling
	Ginkgolic acid C17:1 是分离自银杏叶中，通过诱导PTEN 和SHP-1酪氨酸磷酸酶抑制组成型和诱导型 STAT3 活化。它具有抗癌活性。
T13750	L-Fucitol L-岩藻糖醇,1-Deoxy-D-galactitol	Others	Others
	L-Fucitol (1-Deoxy-D-galactitol) 是一种糖醇，从肉豆蔻 (Nutmeg) 中分离得到。
T5055	For-Met-OH fMet,N-甲酰甲硫氨酸,N-Formyl-L-methionine	Others; Endogenous Metabolite	Metabolism; Others
	For-Met-OH (N-Formyl-L-methionine) 是内源性代谢产物的一种。
T2S0493	Isoeugenol 4-Propenylguaiacol,2-Methoxy-4-propenylphenol,异丁香酚,异丁香酚;4-丙烯基-2-甲氧基苯酚、对丙烯基邻甲氧基本酚、异丁子香酚	Antibacterial	Microbiology/Virology
	Isoeugenol (4-Propenylguaiacol) 是肉豆蔻，丁香和肉桂的精油成分，具有抗菌活性。它抑制Escherichia coli 和Listeria innocua，MIC 值分别为 0.6 mg/mL 和 1 mg/mL。
TN7224	2,2'-Dihydroxy chalcone	Antibacterial; Autophagy	Autophagy; Microbiology/Virology
	2,2'-Dihydroxy chalcone 是一种用 fMLP/CB 刺激的大鼠中性粒细胞释放β-葡糖醛酸酶（IC50=1.6±0.2μM）和溶菌酶（IC50=1.4±0.2μM）的有效抑制剂。2,2'-Dihydroxy chalcone 对大肠杆菌、福氏志贺氏菌、白葡萄球菌和金黄色葡萄球菌有抑菌活性。
T2O2707	D-(+)-Fucose	Others	Others
	D-(+)-Fucose 是一种 l-阿拉伯糖的非代谢类似物，也是 β-甲基半乳糖苷透皮酶诱导剂。它能够抑制 l-阿拉伯糖操纵子的诱导，阻断大肠杆菌 B/r 在矿物盐培养基上加 l-阿拉伯糖的生长。
T4S0867	Pogostone DHELWANGIN,广藿香酮	Apoptosis; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology
	Pogostone (DHELWANGIN) 是从薄荷中分离出，对革兰氏阴性菌、革兰氏阳性菌、大肠埃希菌等具有强效抗菌、抗真菌活性。它诱导细胞凋亡和自噬。
T26747	BB-3497 BB 3497,BB3497
	BB-3497, a potent inhibitor of Escherichia coli peptide deformylase, has antibacterial activity both in vitro and in vivo.
TN1203	2,3,8-Tri-O-methylellagic acid 2,3,8-三邻甲基鞣花酸	Antifection	Microbiology/Virology
	2,3,8-tri-O-Methyl ellagic acid has antimicrobial activity agaist Vibro cholera, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus cereus, Escherichia coli.
TN4927	Rupesin E	Antifection	Microbiology/Virology
	Rupesin E shows significant antibacterial activities against Escherichia coli.
T72250	4aα,7α,7aα-Nepetalactone	Others	Others
	4aα,7α,7aα-Nepetalactone 具有抗菌 (antibacterial) 活性，抑制Escherichia coli，Pseudomonas aeruginosa，Staphylococcus aureus，Salmonella typhi 和Enterococcus faecalis。
T40529	(R)-(-)-1,2-Propanediol	Others	Others
	(R)-(-)-1,2-Propanediol is the (R)-enantiomer of 1,2-Propanediol, which is derived from glucose through the expression of NADH-linked glycerol dehydrogenase genes in Escherichia coli.
TN2760	2-Hydroxy-1,8-cineole	Antifection	Microbiology/Virology
	1. 2-endo-Hydroxy-1,8-cineole shows antimicrobial and bactericidal activities against against test bacteria (Staphylococcus aureus, Escherichia coli, and Pseudomonas fluorescens) .<BR/>
TN2820	24-Methylenecycloartan-3-ol	Antifection	Microbiology/Virology
	24-Methylenecycloartan-3-ol and methyl caffeate show weak activity against Staphylococcus aureus and Escherichia coli.
TN4579	Monomethylsulochrin	Antifection	Microbiology/Virology
	Monomethylsulochrin shows antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus. It shows moderately inhibitory effects on the human bacterial pathogen Helicobacter pylori with the MIC value of 28.9+/-0.1 microM.
T80354	Maximin 39	Others	Others
	Maximin 39为源自蟾蜍大脑的抗菌肽，具有针对金黄色葡萄球菌（Staphylococcus aureus）和大肠杆菌（Escherichia coli）的活性，其最小抑菌浓度（MIC）值分别为18.8 μg/mL和37.5 μg/mL。
T40814	Colominic acid sodium salt Polysialic acid sodium salt,Colominic acid sodium salt	Others	Others
	Colominic acid sodium salt, also known as polysialic acid sodium salt, is naturally isolated from the cell wall of Escherichia coli and animals. It exhibits a red color with an absorption maximum of 530 nm and possesses anti-bacterial activity.
TN3400	Altechromone A	Antifection	Microbiology/Virology
	Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively.
TN4731	Pachyaximine A	Antifection	Microbiology/Virology
	Pachyaximine A possesses significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. (-)-Pachyaximine A demonstrates significant activity as antiestrogen binding site (AEBS
T80335	Maximin H3	Others	Others
	Maximin H3，源自中华红腹蟾蜍Bombina maxima皮肤分泌，为一种抗菌肽。对Escherichia coli ATCC 25922、Staphylococcus aureus ATCC 2592、Bacillus pyocyaneus CMCC B1010 及Candida albicans ATCC 2002表现出显著抗性，其MIC值依次为20, 10, 20, 5 μg/ml。
T80351	Maximin 28	Others	Others
	Maximin 28为源自蟾蜍大脑的抗菌肽，对金黄色葡萄球菌(Staphylococcus aureus)、大肠杆菌(Escherichia coli)及枯草芽孢杆菌(Bacillus subtilis)表现出抗菌活性，其MIC值分别为4.7、9.4、75 μg/mL。
TN3403	Djalonensone 交链孢霉甲基醚,Alternariol monomethyl ether	Immunology/Inflammation related	Immunology/Inflammation
	Djalonensone (Alternariol monomethyl ether) 具有强大的 DPPH 自由基清除作用。
T79986	Brevianamide M	Others	Others
	Brevianamide M (compound 4)为Aspergillus versicolor代谢物，该物质源自海洋褐藻Ecklonia马尾藻中分离的内生真菌。Brevianamide M展示出针对大肠杆菌和金黄色葡萄球菌的抗菌活性。
T80334	Maximin H2	Others	Others
	Maximin H2，源自中华红腹蟾蜍(Bombina maxima)皮肤分泌物的抗菌肽，对Escherichia coli ATCC25922、Staphylococcus aureus ATCC2592、Bacillus pyocyaneus CMCCB1010及Candida albicans ATCC2002展示了明显的抗菌活性。其最小抑菌浓度(MIC)值依序为20、2、4、2 μg/ml。
T80349	Maximin H4	Others	Others
	Maximin H4是一种来自中华红腹蟾蜍(Bombina maxima)皮肤分泌物的抗菌肽，具有针对Escherichia coli ATCC25922、Staphylococcus aureus ATCC2592、Bacillus pyocyaneus CMCCB1010和Candida albicans ATCC2002的抗菌活性。其最小抑菌浓度(MIC)值依次为12、6、12、6 μg/ml。
T80355	Bombinin H1	Others	Others
	Bombinin H1是Bombina variegata蛾皮肤中提取的抗菌肽。该肽对大肠杆菌D21的致死浓度为3.8μM，而对金黄色葡萄球菌Cowan 1的致死浓度为2.1μM。
T80001	Majoranaquinone	Antibiotic	Microbiology/Virology
	Majoranaquinone对4种Staphylococcus菌株、1种Moraxella菌株和1种Enterococcus菌株显示出良好的抑菌作用。此外，Majoranaquinone在E.coli ATCC 25922菌株中表现出显著的外排泵抑制活性，并能有效抑制E.coli ATCC 25922和E.coli K-12 AG100的生物膜形成。
T80332	Maximin H1	Others	Others
	Maximin H1是一种抗菌肽，由中华红腹蟾蜍(Bombina maxima)皮肤分泌物提取得到。该化合物对Escherichia coli ATCC 25922、Staphylococcus aureus ATCC 25923、Bacillus pyocyaneus CMCC B1010和Candida albicans ATCC 2002表现出抗菌活性，其最小抑菌浓度(MIC)值分别为9、4.5、9、4.5 μg/ml。
T80350	Maximin 15	Others	Others
	Maximin 15为源自蟾蜍大脑的抗菌肽，具有针对金黄色葡萄球菌、大肠杆菌和枯草芽孢杆菌的活性，其最小抑菌浓度(MIC)值依次为9.4, 18.8, 75 μg/mL。
T80358	Bombinin H3	Others	Others
	Bombinin H3为源自蛾Bombina variegata皮肤的抗菌肽。其对大肠杆菌D21的致死浓度为3.7 μM，而针对金黄色葡萄球菌Cowan 1的致死浓度为2.4 μM。
TN2626	14-Norpseurotin A	Antifection	Microbiology/Virology
	14-Norpseurotin A shows good antileishmanial and moderate anticancer activities. It also displays significant antimicrobial activities against Escherichia coli, Bacillus subtilis, and Micrococcus lysoleikticus with MICs of 3.74, 14.97, and 7.49 microM , r
T80360	Bombinin H4	Others	Others
	Bombinin H4，蛾Bombina variegata皮肤中的抗菌肽，其对大肠杆菌D21和金黄色葡萄球菌Cowan 1的致死浓度分别为4.8 μM和3.3 μM。
T80353	Maximin 32	Others	Others
	Maximin 32 是源于蟾蜍大脑的抗菌肽，对金黄色葡萄球菌和大肠杆菌表现出活性，其 MIC 值分别为 9.4 和 18.8 μg/mL。
T80352	Maximin 31	Others	Others
	Maximin 31 是抗菌肽，源自蟾蜍大脑。该化合物对金黄色葡萄球菌和大肠杆菌表现出抗菌活性，其最小抑菌浓度（MIC）值分别为 37.5 μg/mL 和 75 μg/mL。
TN4402	Labd-13-ene-8,15-diol	Antifection	Microbiology/Virology
	13(E)-Labd-13-ene-8alpha,15-diol shows antiviral and anticancer activity, it shows strong anti-HRV2 and HRV3 activity with a 50% inhibitory concentration (IC50) of 2.68 and 0.87 microg/mL,respectively; it also exhibits antilung and antilaryngeal cancer ac

天然产物

Cat.No: T2904

Synonym: 香紫苏内酯,Norambreinolide

Target: Others, Antibacterial

Cat.No: T0909

Synonym: 萘啶酸,NSC-82174

Target: Topoisomerase, Antibacterial, Antibiotic

Spectinomycin dihydrochloride

Cat.No: T0788

Synonym: 淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin

Target: ribosome, Antibacterial, Antibiotic

D-Ribonolactone

Cat.No: T10941

Synonym: D-(+)-核糖酸-1,4-内酯,D-核糖内酯

Target: Endogenous Metabolite, Antibacterial

Cat.No: TF0083

3-Hydroxycapric acid

Cat.No: T7565

Target: Endogenous Metabolite

Ginkgolic acid C17:1

Cat.No: T6S2116

Synonym: 银杏酸 C17:1,银杏酸C17:1

Target: Phosphatase, PTEN

Cat.No: T13750

Synonym: L-岩藻糖醇,1-Deoxy-D-galactitol

Target: Others

Cat.No: T5055

Synonym: fMet,N-甲酰甲硫氨酸,N-Formyl-L-methionine

Target: Others, Endogenous Metabolite

Cat.No: T2S0493

Synonym: 4-Propenylguaiacol,2-Methoxy-4-propenylphenol,异丁香酚,异丁香酚;4-丙烯基-2-甲氧基苯酚、对丙烯基邻甲氧基本酚、异丁子香酚

Target: Antibacterial

2,2'-Dihydroxy chalcone

Cat.No: TN7224

Target: Antibacterial, Autophagy

Cat.No: T2O2707

Target: Others

Cat.No: T4S0867

Synonym: DHELWANGIN,广藿香酮

Target: Apoptosis, Antibacterial, Autophagy

Cat.No: T26747

Synonym: BB 3497,BB3497

2,3,8-Tri-O-methylellagic acid

Cat.No: TN1203

Synonym: 2,3,8-三邻甲基鞣花酸

Target: Antifection

Cat.No: TN4927

Target: Antifection

4aα,7α,7aα-Nepetalactone

Cat.No: T72250

Target: Others

(R)-(-)-1,2-Propanediol

Cat.No: T40529

Target: Others

2-Hydroxy-1,8-cineole

Cat.No: TN2760

Target: Antifection

24-Methylenecycloartan-3-ol

Cat.No: TN2820

Target: Antifection

Monomethylsulochrin

Cat.No: TN4579

Target: Antifection

Cat.No: T80354

Target: Others

Colominic acid sodium salt

Cat.No: T40814

Synonym: Polysialic acid sodium salt,Colominic acid sodium salt

Target: Others

Cat.No: TN3400

Target: Antifection

Cat.No: TN4731

Target: Antifection

Cat.No: T80335

Target: Others

Cat.No: T80351

Target: Others

Cat.No: TN3403

Synonym: 交链孢霉甲基醚,Alternariol monomethyl ether

Target: Immunology/Inflammation related

Cat.No: T79986

Target: Others

Cat.No: T80334

Target: Others

Cat.No: T80349

Target: Others

Cat.No: T80355

Target: Others

Majoranaquinone

Cat.No: T80001

Target: Antibiotic

Cat.No: T80332

Target: Others

Cat.No: T80350

Target: Others

Cat.No: T80358

Target: Others

14-Norpseurotin A

Cat.No: TN2626

Target: Antifection

Cat.No: T80360

Target: Others

Cat.No: T80353

Target: Others

Cat.No: T80352

Target: Others

Labd-13-ene-8,15-diol

Cat.No: TN4402

Target: Antifection

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02447	Shiga toxin II subunit B Protein, E. coli, Recombinant (His)	E. coli	E. coli
	E. Coli STX2B is a subunit of Stx2. Stx2, together with Stx1, formed a family of related toxins which are known as shiga toxins. Shiga toxins are mainly produced by the bacteria S. dysenteriae and the Shigatoxigenic group of Escherichia coli, which includes serotypes O157:H7, O104:H4, and other enterohemorrhagic E. coli (EHEC). A total of 3222 outbreak cases (including 39 deaths) have been reported in northern Germany in May through June 2011. The outbreak strain was typed as an enteroaggregativ...
TMPK-00550	CD55/DAF Protein, Cynomolgus, Recombinant (His) TC,DAF-GPI,CR,CROM,Daf1,CD55,Cd55a,DAF	Cynomolgus	HEK293 Cells
	Decay Accelerating Factor (or CD55) is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. It is commonly hijacked by invading pathogens, including many enteroviruses and uropathogenic Escherichia coli, to promote cellular attachment prior to infection.
TMPH-00755	Integrase Protein, Escherichia phage lambda, Recombinant (His) Integrase,int	Escherichia phage lambda	E. coli
	Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. Integrase Protein, Escherichia phage lambda, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 46.3 kDa and the accession number is P03700.
TMPY-02375	acnB Protein, E. coli, Recombinant yacI,yacJ	E. coli	E. coli
	Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to SoxRS-mediated activation, whereas acnB encodes the major aconitase that is synthesized earlier in the growth cycle than AcnA. It is concluded that AcnB is the major citric acid cycle enzyme. Aconitate hydratase 2 (acnB) catalyzes the isomerization of citrate to isocitrate via cis-a...
TMPK-00819	CD42a/GP9 Protein, Human, Recombinant (hFc) CD42a,GP-IX,GP9,Glycoprotein 9,GPIX	Human	HEK293 Cells
	Filamentous M13 phage extrude from infected Escherichia coli with a tip structure composed of gp7 and gp9. This tip structure is extended by the assembly of the filament composed of the major coat protein gp8. gp7, gp8 and gp9 could also be used for phage display and these phage particles should bind to two different or more surfaces when the modified coat proteins are combined. The gp9 at the phage tip is suitable for the phage display technology.
TMPH-00754	Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST) Gene product D,Auxiliary protein D,Major capsid protein D,gp...	Escherichia phage lambda	E. coli
	Stabilizes the expansion of the capsid head shell after genome packaging. The packaging of viral genome in the procapsid triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while the capsid thickness decreases. 415 capsid decoration protein molecules cooperatively bind the expanded capsid, thereby stabilizing the mature capsid shell. Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST) is expressed in E. coli expression system with N-GST...
TMPY-00248	Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His) Lymphotoxin β,lymphotoxin β (TNF superfamily, member 3),lymp...	Cynomolgus	Baculovirus Insect Cells
	LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. Heat-labile enterotoxin B subunit (LTB) of enterotoxigenic Escherichia coli (ETEC) is both a strong mucosal adjuvant and immunogen. It is a subunit vaccine candidate to be used against ETEC-induced diarrhea. It has already been expressed in seve...
TMPY-02120	XPNPEP2 Protein, Human, Recombinant (His) AEACEI,X-prolyl aminopeptidase (aminopeptidase P) 2, membran...	Human	HEK293 Cells
	Aminopeptidase P (APP) is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. A membrane-bound and soluble form of this enzyme (XPNPEP2) have been identified as products of two separate genes. XPNPEP2, the X-linked gene that encodes membranous aminopeptidase P (APP), has been reported to associate with APP activity. The membrane aminopeptidase P (XPNPEP2) is largely limited in distribution ...
TMPH-03746	NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated Fe/S biogenesis protein NfuA,nfuA	ENT-Escherichia coli	E. coli
	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The predicted molecular weight is 68.8 kDa and the accession number is B1X760.

重组蛋白

Shiga toxin II subunit B Protein, E. coli, Recombinant (His)

Cat.No: TMPY-02447

Species: E. coli

Expression System: E. coli

CD55/DAF Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00550

Species: Cynomolgus

Expression System: HEK293 Cells

Integrase Protein, Escherichia phage lambda, Recombinant (His)

Cat.No: TMPH-00755

Species: Escherichia phage lambda

Expression System: E. coli

acnB Protein, E. coli, Recombinant

Cat.No: TMPY-02375

Species: E. coli

Expression System: E. coli

CD42a/GP9 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00819

Species: Human

Expression System: HEK293 Cells

Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST)

Cat.No: TMPH-00754

Species: Escherichia phage lambda

Expression System: E. coli

Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-00248

Species: Cynomolgus

Expression System: Baculovirus Insect Cells

XPNPEP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02120

Species: Human

Expression System: HEK293 Cells

NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated

Cat.No: TMPH-03746

Species: ENT-Escherichia coli

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T40376	L-Phenylalanine-15N L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) 是 15N 标记的 L-Phenylalanine。L-Phenylalanine 是从大肠杆菌中分离出来的一种必需氨基酸。 L-Phenylalanine 广泛用于食品香精和药物的生产。

同位素标记化合物

L-Phenylalanine-15N

Cat.No: T40376

Synonym: L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N

Target: Calcium Channel

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