Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00538 |
Epstein-Barr virus (strain GD1) EBNA3 Protein (His & Myc)
Epstein-Barr nuclear antigen 3A,<... |
EBV | E. coli |
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop. |