40
22
1
9
1
Cat. No. | Product Name | ||
---|---|---|---|
L1520 | 膜蛋白靶向化合物库 | 4175 compounds | |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMAZ-0077A6 |
Anti-EMB Monoclonal Antibody-AF647
|
||
Anti-EMB Monoclonal Antibody-AF647 is a biotin-conjugated humanized rabbit antibody targeting EMB. Anti-EMB Monoclonal Antibody-AF647 can be used FACS. | |||
TMAZ-0077P |
Anti-EMB Monoclonal Antibody-PE
|
||
Anti-EMB Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting EMB. Anti-EMB Monoclonal Antibody-PE can be used FACS. | |||
TMAZ-0077B |
Anti-EMB Monoclonal Antibody-Biotin
|
||
Anti-EMB Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting EMB. Anti-EMB Monoclonal Antibody-Biotin can be used FACS. | |||
TMAZ-0077A |
Anti-EMB Monoclonal Antibody-APC
|
||
Anti-EMB Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting EMB. Anti-EMB Monoclonal Antibody-APC can be used FACS. | |||
TMAZ-0077A4 |
Anti-EMB Monoclonal Antibody-AF488
|
||
Anti-EMB Monoclonal Antibody-AF488 is a biotin-conjugated humanized rabbit antibody targeting EMB. Anti-EMB Monoclonal Antibody-AF488 can be used FACS. | |||
TMAZ-0077A5 |
Anti-EMB Monoclonal Antibody-AF555
|
||
Anti-EMB Monoclonal Antibody-AF555 is a biotin-conjugated humanized rabbit antibody targeting EMB. Anti-EMB Monoclonal Antibody-AF555 can be used FACS. | |||
T2711 |
Chembridge-5861528
TCS 5861528 |
TRP/TRPV Channel | Membrane transporter/Ion channel |
Chembridge-5861528 (TCS 5861528) 是有效的 TRPA1离子通道阻断剂。 | |||
T67988 |
Embeconazole
R 120758,CS 758 |
Antifungal | Microbiology/Virology |
Embeconazole (R 120758) 是一种三唑类抗真菌剂。Embeconazole 对念珠菌、曲霉菌、新型隐球菌等临床重要真菌具有较强的体外活性。 | |||
T77439 |
Glembatumumab
|
Others; ADC Antibody | Antibody-drug Conjugate/ADC Related; Others |
Glembatumumab 是一种靶向在人类乳腺癌和黑色素瘤中表达的 GPNMB 细胞外结构域的完全人类 IgG2 单克隆抗体。Glembatumumab 是 Glembatumumab vedotin 的裸抗,可用于研究抗体-活性分子偶联物(Glembatumumab vedotin ) 。 | |||
T60092 |
CHEMBL1276927
N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide,N-[3-(1H-苯并[d]咪唑-2-基)苯基]-3-甲基苯甲酰胺 |
Antibacterial; Parasite | Microbiology/Virology |
CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) 对肺炎衣原体和多诺瓦尼利什曼原虫具有抗菌和抗寄生虫活性。 | |||
T74178 |
Glembatumumab vedotin
CR011-vcMMAE,CR 011 ADC,CDX-011 |
Microtubule Associated; Antibody-Drug Conjugates (ADCs) | Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling |
Glembatumumab vedotin (CDX-011) 是一种抗体活性小分子偶联物,Glembatumumab vedotin 具有强大的抗癌作用,可用于研究三阴性乳腺癌(TNBC)。 | |||
T2429 |
Olverembatinib dimesylate
GZD824 Dimesylate,HQP1351 |
Bcr-Abl | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Olverembatinib dimesylate (GZD824 Dimesylate) 是一种高效的、口服具有活性的pan-Bcr-Abl 抑制剂,具有抗肿瘤活性。它能广泛而有效地抑制突变型 Bcr-Abl。它对天然的 Bcr-Abl 和 Bcr-AblT315I 作用的IC50值分别为 0.34 nM 和 0.68 nM。 | |||
TP2417 |
Tidembersat
|
Others | Others |
Tidembersat 是一种小分子化合物,可用于治疗和/或预防退行性疾病,如亨廷顿舞蹈病、精神分裂症、神经。 | |||
TP1286 |
Carcinoembryonic Antigen CEA
癌胚抗原 |
Others | Others |
Carcinoembryonic Antigen CEA 是一种广谱性肿瘤标志物,是大肠癌组织产生的一种糖蛋白,作为抗原可引起患者的免疫反应。 | |||
T9908 |
Pembrolizumab
|
PD-1/PD-L1 | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation |
Pembrolizumab 是一种抑制 PD-1 受体的人源化单克隆抗体,是一个 HER2 二聚化抑制剂类,它会削弱 HER2 与 HER 家族其他成员结合的能力。 | |||
T8598 |
CHEMBL241987
2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
CHEMBL241987 靶向腺苷受体 A3(人)。 | |||
T60093 |
CHEMBL1380345
N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide) |
Antibacterial | Microbiology/Virology |
CHEMBL1380345 对金黄色葡萄球菌、蜡状芽孢杆菌和大肠杆菌具有抗菌活性,pMIC 值分别为 3.64、3.56 和 3.70。 | |||
T28750 |
Sembragiline
RG-1577,EVT-302,RO-4602522,RO4602522,RG1577,EVT302 |
MAO | Metabolism; Neuroscience |
Sembragiline (EVT-302) 是一种具有选择性的 MAO-B 抑制剂,可用于研究阿尔茨海默病(AD)。 | |||
T27112 |
Cytembena
|
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Cytembena 是一种细胞抑制剂,是一种致癌化合物,可之间纤维腺瘤发生的几率。Cytembena 广泛地抑制 DNA 的生物合成。 | |||
T3071 |
Olverembatinib
GZD 824 |
Bcr-Abl | Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Olverembatinib (GZD 824) 是一种高效的、口服具有活性的pan-Bcr-Abl 抑制剂,具有抗肿瘤活性。它能广泛而有效地抑制突变型 Bcr-Abl。它对天然的 Bcr-Abl 和 Bcr-AblT315I 作用的IC50值分别为 0.34 nM 和 0.68 nM。 | |||
T81824 |
Membrane-Permeable Sequence, MPS
|
||
Membrane-Permeable Sequence(MPS)是一种CPP,常用于研究跨膜机制。 | |||
T69405 |
Metformin embonate
|
Others | Others |
Metformin embonate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. | |||
T28749 |
SEMBL
|
Others | Others |
SEMBL, a novel inhibitor of DNA binding of NF-kappaB component p65 in vitro, inhibits NF-kappaB and cellular invasion in ovarian carcinoma ES-2 cells. | |||
T131083 |
Cembratetraene-16,2:19,6-diolide
|
Others | Others |
Cembratetraene-16,2:19,6-diolide 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131083。 | |||
T124625 |
α-Cembrenediol
|
Others | Others |
α-Cembrenediol 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124625。 | |||
T70261 |
Amitriptyline Embonate
|
Others | Others |
Amitriptyline Embonate is an inhibitor of the re-uptake of norepinephrine and serotonin, thereby inhibiting N-methyl-D-aspartate (NMDA) receptors. | |||
T70054 |
Novembichin
|
Others | Others |
Novembichin is a nitrogen mustard agent that crosslinks with DNA, causing inhibition of DNA synthesis. | |||
T124052 |
Calophymembranside B
|
Others | Others |
Calophymembranside B 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124052,CAS号为 869285-60-9。 | |||
T68384 |
SCHEMBL12616233
|
Others | Others |
SCHEMBL12616233 is a novel inhibitor of SARS-CoV-2 main protease (MPro). | |||
T82476 |
Embramine hydrochloride
|
Others | Others |
Embramine (hydrochloride) 为具有抗组胺及抗胆碱能特性的单乙醇胺类化合物。 | |||
T80209 |
Human membrane-bound PD-L1 polypeptide
|
PD-1/PD-L1 | Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation |
Human membrane-bound PD-L1 polypeptide 作为抗原,可诱导生成相应的PD-L1抗体。 | |||
T11180 |
Embramine
|
Others | Others |
Embramine, used as an antihistamine and anticholinergic, is a monoethanolamine. | |||
TP2198 |
Platelet Membrane Glycoprotein IIB Peptide (296-306)
|
Others | Others |
GPllb is composed of a 125 Kd heavy chain that is disulfide-linked to a 23 Kd light chain. Hydropathicity analysis of the cDNA sequence indicates that GPllb is anchored to the platelet through a single transmembrane domain located within 20 amino acids of | |||
T124967 |
D7-Mesembrenone
|
Others | Others |
D7-Mesembrenone 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124967,CAS号为 35714-44-4。 | |||
T131462 |
Embelin Dimethyl ether
|
Others | Others |
Embelin Dimethyl ether 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131462。 | |||
T31619 |
Embusartan
UNII-4MY73645XA,Bay 10-6734 |
Others | Others |
Embusartan (BAY 10-6734) is a potent, orally active angiotensin II receptor antagonist used as an antihypertensive agent. | |||
T31373 |
Dembrexine HCl
Dembroxol |
Others | Others |
Dembrexine is a bioactive agent. | |||
T71902 |
CHEMBL94431
|
Others | Others |
CHEMBL94431 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. | |||
T76916 | Bafisontamab | ||
Bafisontamab (EMB-01) 是一种靶向EGFR 和cMET 的双特异性抗体,具有抗肿瘤活性。 | |||
T37880 |
OPC-167832
|
Others | Others |
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-167832 exhibits very low MICs against laboratory strains of M. tuberculosis H37Rv (MIC: 0.0005 μg/ml) and Kurono (MIC: 0.0005 μg/ml) and strains with monoresistance to rifampin (RIF), isoniazid (INH), ethambutol (EMB), streptomycin (STR), and pyrazinamide (PZA) (MIC: 0.00024-0.001 ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0810 |
Ethambutol dihydrochloride
Ethambutol 2HCl,盐酸乙胺丁醇,Emb dihydrochloride,CL40881 |
Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Ethambutol dihydrochloride (CL40881) 能抗分枝杆菌,可抑制阿拉伯糖基转移酶活性来阻止细胞壁形成。 | |||
T2S1682 |
Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside |
Amylase | Metabolism |
Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside 可抑制 α-淀粉酶活性,IC50值为0.03 umol/ml。 | |||
T2992 |
Pinocembrin
乔松素,5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone,松属素 |
NF-κB; Reactive Oxygen Species; Antibacterial; Autophagy | Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Pinocembrin (5,7-Dihydroxyflavanone) 是从蜂胶中得到的黄酮类物质,是一种竞争性组氨酸脱羧酶抑制剂,也是抗过敏剂,具有抗氧化、抗菌、抗炎的作用。 | |||
T13514 |
5-MethoxyPinocembroside
|
Others | Others |
5-MethoxyPinocembroside 是一种黄酮类天然产物,存在于辣木 Moringa oleifera 的叶子中。 | |||
TN2078 |
Pinocembrin chalcone
2',4',6'-Trihydroxychalcone,Pinocembrinchalcone |
Calcium Channel; Tyrosinase; Antibacterial; Antifection | Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Proteases/Proteasome |
Pinocembrin chalcone 是一种具有抗诱变作用的酪氨酸酶抑制剂。 Pinocembrin 查尔酮可用于预防胃溃疡的研究。 | |||
T5710 |
Pinocembrin-7-O-β-D-glucopyranoside
Pinocembrin 7-O-beta-D-glucoside,乔松素7-O-Β-D葡萄糖苷,乔松苷 |
Others | Others |
Pinocembrin-7-O-β-D-glucopyranoside (Pinocembrin 7-O-beta-D-glucoside) 是黄酮类化合物,能够提高脂质过氧化。 | |||
T6485 |
Embelin
NSC 91874,恩贝酸,恩贝酸/恩贝灵,Emberine,Embelic acid |
Apoptosis; NF-κB; Lipoxygenase; IAP; Prostaglandin Receptor; Autophagy | Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism; NF-κB |
Embelin (Embelic acid) 是从日本 Ardisia 草药中分离出来的一种非肽类细胞渗透性XIAP 抑制剂,诱导口腔鳞癌细胞自噬和凋亡。它阻断 NF-kappaB 信号通路,从而抑制 NF-kappaB 调节的抗凋亡和转移基因产物。在高水平 XIAP 的前列腺癌细胞中抑制细胞生长,诱导凋亡,并激活 caspase-9。 | |||
TN4221 |
Homoembelin
2,5-dihydroxy-3-nonyl-1,4-benzoquinone |
Antibacterial | Microbiology/Virology |
Homoembelin (2,5-dihydroxy-3-nonyl-1,4-benzoquinone) 是来自 E. ribes 和 C. monocarpus 的色素,具有抗菌效果,可用于耐多药细菌感染的研究。 | |||
TN2077 |
(+/-)-Pinocembrin
NSC 43318,(±)-5,7-Dihydroxyflavanone |
GPR; Others | Endocrinology/Hormones; GPCR/G Protein; Others |
(+/-)-Pinocembrin (NSC-43318) 是一种来自腋松的天然产物,它是一种 GPR120 配体,能促进 HaCaT 细胞系的伤口愈合。 | |||
TN5509 |
(2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside
(2S)-Pinocembrin 7-O-[cinnamoyl(1→5)-β-D-apiosyl(1→2)]-β-D-glucoside |
||
(2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5509,CAS号为 773899-29-9。 | |||
T35434 |
β-Cembrenediol
|
Others | Others |
β-Cembrenediol (β-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate. β-CBT inhibits induction of the early antigen of Epstein-Barr virus (EA-EBV) by 12-O-tetradecanoylphorbol-13-acetate (TPA) in vitro (IC50 = 21.9 μM). It inhibits tumor promoting effects of TPA on 7,12-demethylbenz[a]anthracene-induced papilloma formation in vivo. β-CBT is also released into soil by flue-cured tobacco plants and exerts autotoxicity as well as phytotoxic activity against L.... | |||
TN6319 |
Embinin
|
||
Embinin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6319,CAS号为 52589-13-6。 | |||
T77289 |
5-O-Methylembelin
|
Others | Others |
5-O-Methylembelin 是一种天然异香豆素,可抑制PCSK9、低密度脂蛋白受体 (IDOL) 和甾醇调节元件结合蛋白 2 (SREBP2) mRNA 的表达。 | |||
T83379 |
2-Hydroxypinocembrin
|
||
2-Hydroxypinocembrin 是一种具有 C-糖基转移酶活性的2-羟基黄烷酮类黄酮底物。 | |||
T28019 |
(-)-Mesembrine
Mesembrin,Mesembrine,Mesembranone |
Others | Others |
Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4). | |||
TN7406 |
Tembetarine
|
Others | Others |
Tembetarine exhibits anti-inflammatory and anti-injury properties and acts as an antifeedant against S. frugiperda. | |||
TN4792 | Pinocembrin diacetate | Others | Others |
Pinocembrin diacetate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4792,CAS号为 111441-88-4。 | |||
TN4791 |
Pinocembrin 7-acetate
|
Others | Others |
Pinocembrin 7-acetate has antitumor activity. | |||
T73857 |
Mesembrine
|
Others | Others |
Mesembrine ((+)-Mesembrine) 一种主要的生物碱,具有芳基八氢吲哚骨架。Mesembrine 是一种5-HT 转运蛋白抑制剂,Ki 为 1.4 nM。Mesembrine 还抑制磷酸二酯酶 4B (PDE4B),IC50为 7.8 μM。 | |||
T72856 |
(+)-Cembrene A
|
Others | Others |
(+)-Cembrene A 是一种α-glucosidase 抑制剂,IC50为 30.31 μM。(+)-Cembrene A 对人正常肝细胞 (LO2) 无毒性。 | |||
T72742 |
(-)-Pinocembrin
(-)-乔松素 |
Others | Others |
(-)-Pinocembrin 对 H37Ra 结核分枝杆菌展示了抗菌活性,无论是休眠还是活跃期,其 IC50 值分别为1.11 mg/mL 和 1.21 mg/mL。作为一种抗增殖剂,(-)-Pinocembrin 对于 THP-1、A549、Panc-1、HeLa 和 MCF7 细胞系,IC50 值范围为 1.88 至 11.00 mg/mL。 | |||
T19772 |
Mesembrenone
(+)-Mesembrenone |
Others | Others |
Mesembrenone is a selective the serotonin transporter (SERT) inhibitor. Mesembrenone is the main alkaloid of Sceletium tortuosum. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02637 |
Embigin Protein, Mouse, Recombinant (His)
Emb,Gp70,Teratocarcinoma glycoprotein Gp-70,Emb... |
Mouse | E. coli |
Plays a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane. Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. Embig... | |||
TMPH-01138 |
Human coronavirus 229E Membrane protein (His)
Matrix glycoprotein,Membrane protein,M,Memb |
HCoV-229E | E. coli |
Human coronavirus 229E Membrane protein (His) is expressed in E. coli. | |||
TMPH-03640 |
34 kDa membrane antigen Protein, Treponema pallidum, Recombinant (His & Myc)
34 kDa membrane antigen,Pathogen-specific memb<... |
Treponema pallidum | E. coli |
This antigen is a pathogen-specific membrane immunogen. 34 kDa membrane antigen Protein, Treponema pallidum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.1 kDa and the accession number is P19478. | |||
TMPY-04904 |
Zika virus (ZIKV) (strain Zika SPH2015) M/Membrane protein (Fc)
|
ZIKV | HEK293 Cells |
Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. ZIKV has a more selective and larger impact on the expression of genes involved in DNA replication and repair. P53 inhibitors can block the apoptosis induced by ZIKV-M in hNPCs. | |||
TMPH-00018 |
29 kDa outer membrane Protein, Acinetobacter baumannii, Recombinant (His & Myc & SUMO)
29 kDa OMP |
Acinetobacter baumannii | E. coli |
May be involved in transporting molecules across the outer membrane. | |||
TMPH-00021 |
Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His)
omp38,Outer membrane protein Omp38 |
Acinetobacter baumannii | P. pastoris (Yeast) |
Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor). | |||
TMPH-00023 |
Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & Myc)
Outer membrane protein Omp38,Outer membran... |
Acinetobacter baumannii | E. coli |
Functions as a porin. Induces apoptosis in human cell lines through caspase-dependent and AIF-dependent pathways. Purified Omp38 enters host cell and localizes to the mitochondria, which presumably leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor). Binds peptidoglycan, contributes to cell wall maintenance (Probable). Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & Myc) is expressed in E. coli expression system with N-1... | |||
TMPH-01151 |
Human coronavirus NL63 Membrane protein (His)
Membrane protein,E1 glycoprotein,M,Matrix glycoprot... |
HCoV-NL63 | E. coli |
Human coronavirus NL63 Membrane protein (His) is expressed in in vitro E. coli expression system. | |||
TMPH-00022 |
Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & SUMO)
omp38,Outer membrane protein Omp38 |
Acinetobacter baumannii | E. coli |
Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor). Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.5 kDa and the accession number is A3M8K2. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIH-0518 |
SCHEMBL19801452-d3
|
||
SCHEMBL19801452-d3 是 SCHEMBL19801452 的氘代化合物。SCHEMBL19801452 的 CAS 号为 2173409-13-5。 |