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Search Results for " ev71 "
Targets Recommended: Others Virus Protease

10

抑制剂 & 化合物

7

天然产物

4

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T18928 Brilliant Black BN

亮黑1,E 151

Others; Virus Protease Microbiology/Virology; Others
Brilliant Black BN (E 151) 是一种偶氮染料和一种食品着色剂。它抑制 EV71 与其细胞脱壳因子亲环蛋白 A 之间的相互作用,是一种很有前途的抗 EV71 感染的抗病毒药物。
T16809 Rupintrivir

AG-7088,AG7088,Rupintrivirvr

Virus Protease; Antiviral Immunology/Inflammation; Microbiology/Virology
Rupintrivirvr (AG7088) 是一种选择性鼻病毒 (HRV) 3C 半胱氨酸蛋白酶的拟肽抑制剂,具有抗病毒活性和免疫调节活性。Rupintrivirvr 抑制 EV71EV-D68 复制,可用于研究病毒感染。
T11329 FT895

HDAC; Antifungal Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology
FT895 是一种具有选择性和有效性的 HDAC11 抑制剂,具有抗真菌和抗肿瘤活性,抑制 HDAC11 表达,限制 EV71在体外复制。
T61334 DMA-135 hydrochloride

DMA-135 HCl

Virus Protease Microbiology/Virology
DMA-135 hydrochloride (DMA-135 HCl) 靶向 RNA 的抗病毒活性化合物,抑制肠道病毒 71 型 (EV71)IRES依赖的翻译和复制。DMA-135 hydrochloride 可用于研究肠道病毒感染。
T13284 Vapendavir diphosphate

BTA798 diphosphate

Others Others
Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).
T13284L Vapendavir

BTA798

Others Others
Vapendavir is a potent enteroviral capsid binder. Vapendavir has an effective antiviral activity for enterovirus 71 replication (EC50: 0.5-1.4 μM in different EV71 strains).
T63563 AN-12-H5

Others Others
AN-12-H5 是一种靶向 PV 和 EV71 病毒的复制过程的抗肠病毒化合物。
T72562 Antiviral agent 23

Others Others
Antiviral agent 23 是肠病毒 71 (EV71) 的抗病毒剂,EC50值为 94 nM。Antiviral agent 23 有效抑制 METTL3/METTL14 的活性。Antiviral agent 23 可用于感染的研究。
T78455 Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2

Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 是一款钌基化合物,既可作为量子点 (QDs) 荧光猝灭剂,也适用于捕获病毒抗原EV71的探针。此外,该化合物还用于作为灵敏的电致化学发光 (ECL) 试剂,用于基质金属蛋白酶 (MMP)[2] 的检测。
T27126 DC07090 Dihydrochloride

Others Others
DC07090 Dihydrochloride is a potent inhibitor of human enterovirus 71 3C protease.

化合物

Brilliant Black BN
Cat.No: T18928
Synonym: 亮黑1,E 151
Target: Others, Virus Protease
Rupintrivir
Cat.No: T16809
Synonym: AG-7088,AG7088,Rupintrivirvr
Target: Virus Protease, Antiviral
FT895
Cat.No: T11329
Synonym:
Target: HDAC, Antifungal
DMA-135 hydrochloride
Cat.No: T61334
Synonym: DMA-135 HCl
Target: Virus Protease
Vapendavir diphosphate
Cat.No: T13284
Synonym: BTA798 diphosphate
Target: Others
Vapendavir
Cat.No: T13284L
Synonym: BTA798
Target: Others
AN-12-H5
Cat.No: T63563
Synonym:
Target: Others
Antiviral agent 23
Cat.No: T72562
Synonym:
Target: Others
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
Cat.No: T78455
Synonym:
Target:
DC07090 Dihydrochloride
Cat.No: T27126
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T8205 Norwogonin

5,7,8-Trihydroxyflavone,去甲汉黄芩素

Virus Protease Microbiology/Virology
Norwogonin (5,7,8-Trihydroxyflavone) 是从黄芩中分离出来的,对肠道病毒 71 具有抗病毒活性,IC50为 31.83 μg/ ml。
T5S2360 Corydaline

Corydalin,紫堇碱,延胡索甲素,(+)-Corydaline

P450; Virus Protease; Opioid Receptor; AChE Endocrinology/Hormones; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
Corydaline (Corydalin) 是从 Corydalis yanhusuo 提取的一种异喹啉生物碱,是一种新型促动力植物药的主要活性成分之一。它促进胃排空和小肠转运,促进胃的调节,具有抗乙酰胆碱酯酶、抗过敏和镇痛活性。
T2843 Aloe emodin

芦荟大黄素,NSC 38628,3-Hydroxymethylchrysazine,Rhabarberone,Aloe-emodin

Autophagy; HSV Autophagy; Microbiology/Virology
Aloe emodin (Rhabarberone) 是从芦荟叶中提取出的一种羟基蒽醌,在体内外有抗肿瘤活性。
T5779 MOSLOFLAVONE

IL Receptor; Virus Protease; TNF; Antibacterial Apoptosis; Immunology/Inflammation; Microbiology/Virology
Mosloflavone 从Scutellaria baicalensis Georgi 中分离出的类黄酮,具有抗EV71活性。它可抑制铜绿假单胞菌的毒力和生物膜形成,有作为杀菌剂的潜力。它在病毒感染的初始阶段抑制 VP2 病毒复制和蛋白质表达,并抑制病毒 VP2 衣壳蛋白合成。
T3795 Corilagin

Apoptosis; TLR; Reverse Transcriptase; Antibacterial; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology
Corilagin 是一种鞣酸,有抑制 RNA 肿瘤病毒逆转录酶的活性。它抑制金黄色葡萄球菌的生长,MIC 为 25 μg/mL。它有抗肿瘤活性,可用于肝癌和卵巢癌。
TN1668 Ganoderic acid Y

灵芝酸Y

Antifection Microbiology/Virology
Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 replication through blocking EV71 uncoating.
TN4748 Penduletin

VEGFR; COX; Prostaglandin Receptor; Antifection Angiogenesis; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; Tyrosine Kinase/Adaptors
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Penduletin has strong activity in vitro against EV71 with low cytotoxicity.

天然产物

Norwogonin
Cat.No: T8205
Synonym: 5,7,8-Trihydroxyflavone,去甲汉黄芩素
Target: Virus Protease
Corydaline
Cat.No: T5S2360
Synonym: Corydalin,紫堇碱,延胡索甲素,(+)-Corydaline
Target: P450, Virus Protease, Opioid Receptor, AChE
Aloe emodin
Cat.No: T2843
Synonym: 芦荟大黄素,NSC 38628,3-Hydroxymethylchrysazine,Rhabarberone,Aloe-emodin
Target: Autophagy, HSV
MOSLOFLAVONE
Cat.No: T5779
Synonym:
Target: IL Receptor, Virus Protease, TNF, Antibacterial
Corilagin
Cat.No: T3795
Synonym:
Target: Apoptosis, TLR, Reverse Transcriptase, Antibacterial, Autophagy
Ganoderic acid Y
Cat.No: TN1668
Synonym: 灵芝酸Y
Target: Antifection
Penduletin
Cat.No: TN4748
Synonym:
Target: VEGFR, COX, Prostaglandin Receptor, Antifection
Cat. No. Product Name Species Expression System
TMPJ-00299 LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc)

LIMP II,Lysosome membrane protein II,SCARB2,85 kDa lysosomal...

Mouse HEK293 Cells
Lysosome membrane protein II (LIMPII),also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junc...
TMPJ-00298 CD36 Protein, Human, Recombinant (aa 27-432, His)

LGP85,Scavenger Receptor Class B Member 2,CD36,Lysosome Memb...

Human HEK293 Cells
Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstructio...
TMPY-02060 Human Enterovirus 71 VP0 Protein (His & GST)

VP Protein,VP4-VP2 Protein

EV71 Baculovirus Insect Cells
Human enterovirus 71 genome polyprotein is a member of the picornaviruses polyprotein family. It contains two peptidase C3 domains, one RdRp catalytic domain, one SF3 helicase domain. Genome polyprotein is cleaved into the following 12 chains: Protein VP (VP4-VP2), Protein VP4 (P1A), Protein VP2 (P1B), Protein VP3 (P1C), Protein VP1 (P1D), Picornain 2A (P2A), Protein 2B (P2B), Protein 2C (P2C), Protein 3A (P3A), Protein 3B (P3B), Picornain 3C (Protease 3C) and RNA-directed RNA polymerase 3D-POL ...
TMPH-02841 Prohibitin Protein, Mouse, Recombinant (His)

Phb1,B-cell receptor-associated protein 32,Prohibitin 1

Mouse E. coli
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells.; In the mitochondria, together with...

重组蛋白

LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00299
Species: Mouse
Expression System: HEK293 Cells
CD36 Protein, Human, Recombinant (aa 27-432, His)
Cat.No: TMPJ-00298
Species: Human
Expression System: HEK293 Cells
Human Enterovirus 71 VP0 Protein (His & GST)
Cat.No: TMPY-02060
Species: EV71
Expression System: Baculovirus Insect Cells
Prohibitin Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02841
Species: Mouse
Expression System: E. coli
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