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Search Results for " egr1 "

Targets Recommended: Epigenetic Reader Domain Histone Acetyltransferase HDAC

3

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T27083	Crebinostat	Epigenetic Reader Domain; Histone Acetyltransferase; HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Crebinostat 是一种有效的组蛋白去乙酰化酶 (HDAC) 抑制剂，对 HDAC1、HDAC2、HDAC3 和 HDAC6 有抑制作用， IC50 分别为 0.7 nM、1.0 nM、2.0 nM 和 9.3 nM。Crebinostat 可增加在体外神经元的突触蛋白 1 斑点沿树突 (synapsin-1 punctae along dendrites) 的密度。Crebinostat 可调节染色质介导的神经可塑性，增强小鼠的记忆。Crebinostat 可诱导组蛋白 H3 和组蛋白 H4 乙酰化，并增强 cAMP 反应元件结合蛋白 (CREB) 靶基因 Egr1 的表达。
T19771	SXT1596 NSC-65667,SXT-1596,NSC 65667,SXT 1596,NSC65667	Others	Others
	SXT1596 is a novel SS18-SSX/TLE1 interaction inhibitor. SXT1596 reduces cell viability and reactivates EGR1 expression in synovial sarcoma.
T63879	microRNA-21-IN-1	Others	Others
	microRNA-21-IN-1（compound 7A）是一种高效microRNA抑制剂，对Hela和HCT-116细胞显示出抗增殖活性，IC50值分别为5.5 μM和2.8 μM，并能促进Hela细胞凋亡(apoptosis)。该化合物通过上调microRNA-21下游功能靶点（PTEN、EGR1、SLIT2）的表达，有助于抗癌研究。

化合物

Cat.No: T27083

Target: Epigenetic Reader Domain, Histone Acetyltransferase, HDAC

Cat.No: T19771

Synonym: NSC-65667,SXT-1596,NSC 65667,SXT 1596,NSC65667

Target: Others

microRNA-21-IN-1

Cat.No: T63879

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00883	EGR1 Protein, Human, Recombinant (His) zinc finger protein 225,NGFI-A,Zif268,Early growth response ...	Human	E. coli
	EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. EGR-1 has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies su...
TMPY-01913	NEGR1 Protein, Human, Recombinant (His) KILON,IGLON4,DMML2433,Ntra,neuronal growth regulator 1	Human	HEK293 Cells
	NEGR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.9 kDa and the accession number is Q7Z3B1-1.
TMPY-01800	NEGR1 Protein, Mouse, Recombinant (His) 5330422G01Rik,KILON,neuronal growth regulator 1...	Mouse	HEK293 Cells
	NEGR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is Q80Z24.
TMPH-03293	FGF-23 Protein, Rat, Recombinant (E. coli, His) Fgf23,Fibroblast growth factor 23	Rat	E. coli
	Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL.
TMPH-03294	FGF-23 Protein, Rat, Recombinant (His) Fibroblast growth factor 23,Fgf23	Rat	P. pastoris (Yeast)
	Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL. FGF-23 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.5 kDa and the accession number is Q8VI82.
TMPH-02613	ATF-5 Protein, Mouse, Recombinant (His & Myc) Transcription factor ATFx,Transcription factor-like protein ...	Mouse	E. coli
	Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation. Its transcrip...

重组蛋白

EGR1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00883

Species: Human

Expression System: E. coli

NEGR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01913

Species: Human

Expression System: HEK293 Cells

NEGR1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01800

Species: Mouse

Expression System: HEK293 Cells

FGF-23 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03293

Species: Rat

Expression System: E. coli

FGF-23 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03294

Species: Rat

Expression System: P. pastoris (Yeast)

ATF-5 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02613

Species: Mouse

Expression System: E. coli

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