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Search Results for " e-101 "
Targets Recommended: Trk receptor ROS ALK Autophagy ROS Kinase

2

抑制剂 & 化合物

1

天然产物

7

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T3678 Entrectinib

RXDX-101,恩曲替尼,NMS-E628

Trk receptor; ROS; ALK; Autophagy; ROS Kinase Angiogenesis; Autophagy; Immunology/Inflammation; Tyrosine Kinase/Adaptors
Entrectinib (RXDX-101) 是一种可口服的 Trk、ROS1和 ALK 抑制剂,具有抗肿瘤和中枢神经活性,抑制 TrkA、TrkB、TrkC、ROS1 和 ALK 的 IC50值分别为 1、3、5、12 和 7 nM。
T77186 Zilovertamab vedotin

Others; Antibody-Drug Conjugates (ADCs) Antibody-drug Conjugate/ADC Related; Others
Zilovertamab vedotin (VLS-101) 是一种抗体-活性分子偶联物 (ADC), 主要由人源化单克隆抗体 zilovertamab 和单甲基 vedotin 组成的抗微管细胞毒素。该药物通过与肿瘤细胞表面的ROR1结合, 触发快速内化及向溶酶体的转运, 进而裂解释放单甲基 vedotin, 诱导细胞凋亡。适用于癌症的研究领域。

化合物

Entrectinib
Cat.No: T3678
Synonym: RXDX-101,恩曲替尼,NMS-E628
Target: Trk receptor, ROS, ALK, Autophagy, ROS Kinase
Zilovertamab vedotin
Cat.No: T77186
Synonym:
Target: Others, Antibody-Drug Conjugates (ADCs)
Cat. No. Product Name Target Signaling Pathways
T0937 Riboflavin

Vitamin B2,维生素B2,E101

Endogenous Metabolite Metabolism
Riboflavin (E101),一种人内源性代谢物, 是极易吸收的微量营养素。

天然产物

Riboflavin
Cat.No: T0937
Synonym: Vitamin B2,维生素B2,E101
Target: Endogenous Metabolite
Cat. No. Product Name Species Expression System
TMPK-01424 Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi)

MHC,HLA-E*01:03,Peptide Ready

Human HEK293 Cells
HLA-E*01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E*01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01545 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

sHLA-E,MHC,MHC class I antigen E,HLAE,MHC HLA-E alpha-1,MHC ...

Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01423 Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,Peptide Ready,HLA-E*01:03

Human HEK293 Cells
HLA-E*01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E*01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01541 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated

QA1,MHC HLA-E alpha-2.1,MHC,HLAE,MHC class I antigen E,MHC H...

Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01544 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)

MHC class I antigen E,HLAE,sHLA-E,QA1,MHC HLA-E alpha-2.1,MH...

Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01452 HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)

HLAE,MHC class I antigen E,MHC,QA1,sHLA-E

Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01514 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)

sHLA-E,MHC class I antigen E,MHC HLA-E alpha-1,MHC,HLAE,QA1,...

Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...

重组蛋白

Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01424
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01545
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01423
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01541
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01544
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01452
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01514
Species: Human
Expression System: HEK293 Cells
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