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Search Results for " drug-linker conjugates for adc "

Targets Recommended: Drug-Linker Conjugates for ADC Others Drug-Linker Conjugates for ADC

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Cat. No.	Product Name	Target	Signaling Pathways
T15098	Deruxtecan	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Deruxtecan 是一种 ADC 药物-接头偶联物，由 DX-8951 (DXd) 的衍生物和马来酰亚胺-GGFG 肽接头组成，用于合成 DS-8201 和 U3-1402。
T18867	Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related
	Val-Cit-PAB-MMAE 是 ADC 的药物-接头偶联物。它包含 ADC 接头（肽 Val-Cit-PAB）和有效的微管蛋白抑制剂 MMAE。
T17983	Fmoc-Val-Cit-PAB-MMAE	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Fmoc-Val-Cit-PAB-MMAE 由 ADC 接头 (Fmoc-Val-Cit-PAB) 和强效微管蛋白抑制剂 (MMAE) 组成。它是一种用于 ADC 的药物-接头偶联物。
T16031	McMMAF Maleimidocaproyl monomethylauristatin F	Microtubule Associated; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	McMMAF 是一种保护基团共轭的 MMAF。它是一种具有马来酰亚胺基己酰基接头（MC 接头）的 MMAF 衍生物， MMAF 是一种有效的微管蛋白聚合抑制剂。它可与抗体或其他蛋白质或生物聚合物结合。
T17731	CL2A-SN-38 CL2A SN 38,CL2A-SN38	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	CL2A-SN-38 由CL2A链接子和抗癌化合物SN-38 组成，可在肿瘤细胞内和肿瘤微环境中递送活性活性分子，通常会与抗体制成具有生物活性的抗体偶联活性分子 (ADC)。
T4232	VCMMAE mc-vc-PAB-MMAE	Microtubule Associated; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	VCMMAE (mc-vc-PAB-MMAE) 是一种用于 ADC 的药物-接头偶联物，具有抗癌活性，它由 MMAE 和 Vc 连接而成。
T12573	Vipivotide tetraxetan PSMA-617	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Vipivotide tetraxetan (PSMA-617) 是一种高效的前列腺特异性膜抗原抑制剂，其Ki 值为 0.37 nM。
T16899	SMCC-DM1 DM1-SMCC	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	SMCC-DM1 (DM1-SMCC) 是一种药物-接头偶联物，由有效的微管破坏剂 DM1 和接头 SMCC 组成，用于制备抗体药物偶联物。
T11917	Lys-SMCC-DM1 Lys-Nε-MCC-DM1	Microtubule Associated; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	DM1 是一种微管蛋白抑制剂。 Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) 是 DM1 的活性代谢物。
T18312	Mc-MMAE Maleimidocaproyl-monomethylauristatin E,马来酰亚胺基己酰-单甲基澳瑞他汀 E	Microtubule Associated; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) 是保护基团 (马来酰亚氨基己酰) 与 MMAE 共轭连接得到的化合物。它是微管蛋白抑制剂，可用于偶联抗体。
T17977	Fmoc-PEA	ADC Linker	Antibody-drug Conjugate/ADC Related
	Fmoc-PEA 是一种可降解的抗体偶联药物 (ADC)的linker。
T18308	MC-Gly-Gly-Phe	ADC Linker	Antibody-drug Conjugate/ADC Related
	MC-Gly-Gly-Phe 是一种用于抗体-药物偶联物的可切割接头。
T17654	Boc-NH-C6-Br N-BOC-6-溴代己胺	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Boc-NH-C6-Br 是一种可切割的 ADC 接头，用于合成抗体-药物偶联物。
T14746	Boc-NH-PEG4-CH2COOH N-叔丁氧羰基-四聚乙二醇-乙酸	PROTAC Linker; ADC Linker	Antibody-drug Conjugate/ADC Related; PROTAC
	Boc-NH-PEG4-CH2COOH 是一种可切割的 ADC 接头，用作抗体-药物偶联物的接头。它也是基于 PEG 的 PROTAC 接头，可用于 PROTAC 的合成。
T18479	NH-bis(C1-Boc) 亚氨基二乙酸二异丁酯	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Boc-NH-C6-Br 是一种不可切割的接头，用于抗体-药物偶联物。
T9282	DBCO-C3-Acid DBCO-ACID	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	DBCO-(CH2)3-Acid 是一种用于抗体-药物偶联物的 Click Chemistry 中间体，可用以合成 ADC linker。
T18870	Vc-MMAD	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Vc-MMAD 由 linker (Val-Cit) 和微管抑制剂 MMAD 组成。Vc-MMAD 可用于偶联抗体。
T18540	Phe-Lys(Trt)-PAB	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Phe-Lys(Trt)-PAB 是一种组织蛋白酶可裂解的 ADC 接头，用于合成抗体-药物偶联物。
T3503	MC-Val-Cit-PABC-PNP Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate,马来酰亚胺基己酰-L-缬氨酸-L-瓜氨酸对氨基苄醇对硝基苯基碳酸脂	Others; AChR; ADC Linker	Antibody-drug Conjugate/ADC Related; Neuroscience; Others
	MC-Val-Cit-PABC-PNP 是一种组织蛋白酶可裂解的 ADC 肽接头，可用于合成抗体偶联药物。
T4286	Fmoc-Val-Ala-PAB-OH Fmoc-Val-Ala-PAB	Others; AChR; ADC Linker	Antibody-drug Conjugate/ADC Related; Neuroscience; Others
	Fmoc-Val-Ala-PAB-OH (Fmoc-Val-Ala-PAB) 是一种有用的接头，可用于制备用于靶向药物递送的抗体-药物偶联物。它还用于合成带有溶酶体可切割接头的 RGD 拟肽-紫杉醇缀合物。
T18309	Mc-Leu-Gly-Arg	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design.
T18718	SPP-DM1	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	SPP-DM1, a drug-linker conjugate for antibody-drug conjugates (ADC), demonstrates potent antitumor activity. It comprises DM1 (a potent microtubule-disrupting agent) connected through the ADC linker SPP[1].
T39111	Fmoc-D-Trp(Boc)-OH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Fmoc-D-Trp(Boc)-OH is a labile ADC linker employed for synthesizing antibody-drug conjugates (ADCs).
T17337	4-N3Pfp-NHS ester	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	4-N3Pfp-NHS ester is a noncleavable ADC linker utilized for synthesizing antibody-drug conjugates (ADCs).
T41074	MB-VC-MGBA	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	MB-VC-MGBA is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADC), utilizing the minor-groove-binding DNA-alkylating agent (MGBA), connected through the ADC linker MB-VC.
T18310	AZ1508 MC-Lys-MMETA	Others	Others
	AZ1508, a tubulin inhibitor[1], serves as a drug-linker conjugate for antibody-drug conjugates (ADC) targeting breast and stomach cancer treatment.
T18511	OPSS-Val-Cit-PAB-OH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	OPSS-Val-Cit-PAB-OH is an ADC linker utilized for the synthesis of antibody-drug conjugates (ADCs) [1].
T15322	Fmoc-NH-PEG8-CH2CH2COOH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Fmoc-NH-PEG8-CH2CH2COOH is a cleavable linker employed for ADC synthesis, primarily in the formation of antibody-drug conjugates (ADCs)[1].
T14771	Br-PEG4-C2-Boc	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Br-PEG4-C2-Boc is a cleavable 4-unit PEG ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].
T18700	SPB	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	SPB is a potent anti-inflammatory drug-linker conjugate for Antibody-Drug Conjugates (ADC), utilizing Xanthotoxol connected through the ADC linker.
T18799	Tetrazine-Ph-OPSS	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Tetrazine-Ph-OPSS is an ADC linker employed for synthesizing ADCs, or antibody-drug conjugates [1].
T18534	PEG4-aminooxy-MMAF	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	PEG4-aminooxy-MMAF is a drug-linker conjugate designed for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. It incorporates MMAF, a powerful antitubulin agent, connected through a non-cleavable PEG4 linker[1].
T18361	MMAE-SMCC	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	MMAE-SMCC is a drug-linker conjugate designed for antibody-drug conjugates (ADC). It consists of MMAE, a potent inhibitor of mitosis and tubulin, and SMCC, a linker that facilitates the development of ADCs.
T38493	MCC-DM1 MCC-DM1	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	MCC-DM1 is a drug-Linker Conjugates for ADC such ad Anti-CD22-MCC-DM1.
T18315	MC-Sq-Cit-PAB-Dolastatin10	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	MC-Sq-Cit-PAB-Dolastatin10 is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), utilizing Dolastatin10 (a tubulin polymerization inhibitor) connected through the MC-Sq-Cit-PAB ADC linker.
T18792	Tetrazine-PEG4-SS-Py	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Tetrazine-PEG4-SS-Py is a cleavable PEG ADC linker comprising four units. It is specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].
T18330	MC-Val-Cit-PAB-vinblastine	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	MC-Val-Cit-PAB-vinblastine is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), featuring vinblastine (a microtubule protein inhibitor) connected through the MC-Val-Cit-PAB ADC linker.
T16880	SIA Crosslinker	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	SIA Crosslinker is a non-cleavable ADC linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].
T16602	Propargyl-PEG2-NHBoc	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Propargyl-PEG2-NHBoc is a cleavable ADC linker utilized for the synthesis of antibody-drug conjugates (ADCs). This PEG-based PROTAC linker, namely Propargyl-PEG2-NHBoc, holds potential for the synthesis of PROTACs[1].
T77822	Mal-PEG8-Val-Ala-PABC	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Mal-PEG8-Val-Ala-PABC是用于合成Tesirine的可剪切Tesirine linker，Tesirine是一种ADC用的drug-linker conjugate。
T17788	DBCO-(PEG2-Val-Cit-PAB)2	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	DBCO-(PEG2-Val-Cit-PAB)2 is a dual cleavable ADC linker for antibody-drug conjugates (ADCs).
T14053	5-Maleimidovaleric acid	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	5-Maleimidovaleric acid, a cleavable linker for antibody-drug conjugates (ADCs) synthesis, is employed as an ADC linker[1].
T39164	MC-betaglucuronide-MMAE-1	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	MC-betaglucuronide-MMAE-1 is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), employing MMAE (a tubulin polymerization inhibitor) connected through the cleavable ADC linker MC-betaglucuronide.
T14752	Boc-NH-PEG6-CH2CH2COOH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[1].
T18320	MC-Val-Cit-PAB-carfilzomib iodide MC-Val-Cit-PAB-carfilzomib	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	MC-Val-Cit-PAB-carfilzomib is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADC), comprising the irreversible proteasome inhibitor carfilzomib, connected through the ADC linker MC-Val-Cit-PAB.
T17149	Tr-PEG2-OH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Tr-PEG2-OH is a PEG-based PROTAC linker utilized in PROTAC synthesis[1]. It also serves as a non-cleavable 2-unit PEG ADC linker for the synthesis of antibody-drug conjugates (ADCs)[2].
T14823	Bromoacetamido-PEG4-acid	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Bromoacetamido-PEG4-acid is a PEG-based PROTAC linker utilized for PROTAC synthesis[1]. It also serves as a cleavable 4-unit PEG ADC linker in the synthesis of antibody-drug conjugates (ADCs)[2].
T18246	Mal-C2-Gly3-EDA-PNU-159682	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	Mal-C2-Gly3-EDA-PNU-159682, a drug-linker conjugate for antibody-drug conjugates (ADC), combines the cleavable ADC linker Mal-C2-Gly3-EDA with the potent ADC cytotoxin PNU-159682.
T17150	Tr-PEG3-OH	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Tr-PEG3-OH is a non-cleavable, three-unit PEG ADC linker employed for ADC synthesis, specifically in the context of antibody-drug conjugates (ADCs).
T18358	Methyltetrazine-SS-NHS	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Methyltetrazine-SS-NHS is a cleavable ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].

化合物

Cat.No: T15098

Target: Others, Drug-Linker Conjugates for ADC

Val-Cit-PAB-MMAE

Cat.No: T18867

Target: Drug-Linker Conjugates for ADC

Fmoc-Val-Cit-PAB-MMAE

Cat.No: T17983

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T16031

Synonym: Maleimidocaproyl monomethylauristatin F

Target: Microtubule Associated, Drug-Linker Conjugates for ADC

Cat.No: T17731

Synonym: CL2A SN 38,CL2A-SN38

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T4232

Synonym: mc-vc-PAB-MMAE

Target: Microtubule Associated, Drug-Linker Conjugates for ADC

Vipivotide tetraxetan

Cat.No: T12573

Synonym: PSMA-617

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T16899

Synonym: DM1-SMCC

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T11917

Synonym: Lys-Nε-MCC-DM1

Target: Microtubule Associated, Drug-Linker Conjugates for ADC

Cat.No: T18312

Synonym: Maleimidocaproyl-monomethylauristatin E,马来酰亚胺基己酰-单甲基澳瑞他汀 E

Target: Microtubule Associated, Drug-Linker Conjugates for ADC

Cat.No: T17977

Target: ADC Linker

Cat.No: T18308

Target: ADC Linker

Cat.No: T17654

Synonym: N-BOC-6-溴代己胺

Target: Others, ADC Linker

Boc-NH-PEG4-CH2COOH

Cat.No: T14746

Synonym: N-叔丁氧羰基-四聚乙二醇-乙酸

Target: PROTAC Linker, ADC Linker

Cat.No: T18479

Synonym: 亚氨基二乙酸二异丁酯

Target: Others, ADC Linker

Cat.No: T9282

Synonym: DBCO-ACID

Target: Others, ADC Linker

Cat.No: T18870

Target: Others, Drug-Linker Conjugates for ADC

Phe-Lys(Trt)-PAB

Cat.No: T18540

Target: Others, ADC Linker

MC-Val-Cit-PABC-PNP

Cat.No: T3503

Synonym: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate,马来酰亚胺基己酰-L-缬氨酸-L-瓜氨酸对氨基苄醇对硝基苯基碳酸脂

Target: Others, AChR, ADC Linker

Fmoc-Val-Ala-PAB-OH

Cat.No: T4286

Synonym: Fmoc-Val-Ala-PAB

Target: Others, AChR, ADC Linker

Cat.No: T18309

Target: Others, ADC Linker

Cat.No: T18718

Target: Others, Drug-Linker Conjugates for ADC

Fmoc-D-Trp(Boc)-OH

Cat.No: T39111

Target: Others, ADC Linker

4-N3Pfp-NHS ester

Cat.No: T17337

Target: Others, ADC Linker

Cat.No: T41074

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T18310

Synonym: MC-Lys-MMETA

Target: Others

OPSS-Val-Cit-PAB-OH

Cat.No: T18511

Target: Others, ADC Linker

Fmoc-NH-PEG8-CH2CH2COOH

Cat.No: T15322

Target: Others, ADC Linker

Cat.No: T14771

Target: Others, ADC Linker

Cat.No: T18700

Target: Others, Drug-Linker Conjugates for ADC

Tetrazine-Ph-OPSS

Cat.No: T18799

Target: Others, ADC Linker

PEG4-aminooxy-MMAF

Cat.No: T18534

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T18361

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T38493

Synonym: MCC-DM1

Target: Others, Drug-Linker Conjugates for ADC

MC-Sq-Cit-PAB-Dolastatin10

Cat.No: T18315

Target: Others, Drug-Linker Conjugates for ADC

Tetrazine-PEG4-SS-Py

Cat.No: T18792

Target: Others, ADC Linker

MC-Val-Cit-PAB-vinblastine

Cat.No: T18330

Target: Others, Drug-Linker Conjugates for ADC

SIA Crosslinker

Cat.No: T16880

Target: Others, ADC Linker

Propargyl-PEG2-NHBoc

Cat.No: T16602

Target: Others, ADC Linker

Mal-PEG8-Val-Ala-PABC

Cat.No: T77822

Target: Others, ADC Linker

DBCO-(PEG2-Val-Cit-PAB)2

Cat.No: T17788

Target: Others, ADC Linker

5-Maleimidovaleric acid

Cat.No: T14053

Target: Others, ADC Linker

MC-betaglucuronide-MMAE-1

Cat.No: T39164

Target: Others, Drug-Linker Conjugates for ADC

Boc-NH-PEG6-CH2CH2COOH

Cat.No: T14752

Target: Others, ADC Linker

MC-Val-Cit-PAB-carfilzomib iodide

Cat.No: T18320

Synonym: MC-Val-Cit-PAB-carfilzomib

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T17149

Target: Others, ADC Linker

Bromoacetamido-PEG4-acid

Cat.No: T14823

Target: Others, ADC Linker

Mal-C2-Gly3-EDA-PNU-159682

Cat.No: T18246

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T17150

Target: Others, ADC Linker

Methyltetrazine-SS-NHS

Cat.No: T18358

Target: Others, ADC Linker

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