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Cat. No. | Product Name | Target | Signaling Pathways |
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T69579 |
Dothiepin HCl
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Others | Others |
Dothiepin HCl is a Tricyclic antidepressant (TCA), acting as a serotonin–norepinephrine reuptake inhibitor (SNRI) and also having other activities including antihistamine, antiadrenergic, antiserotonergic, anticholinergic, and sodium channel-blocking effects. | |||
T78126 |
Dothiepin
Dosulepin,Dothep |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Dothiepin(Dosulepin; Dothep)是一种具备镇静/抗焦虑作用的抗抑郁药物。该化合物主要通过抑制去甲肾上腺素的再摄取,而非血清素,以增强去肾上腺素能神经传递。同时,Dothiepin作为组胺H1受体的拮抗剂,具备显著的镇痛活性,适用于治疗心因性面部疼痛、特发性纤维肌痛综合征或类风湿关节炎,并且不具有心脏毒性。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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TMID-0265 |
Dothiepin-d6 HCl (N,N-dimethyl-d6) (cis/trans mixture)
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Dothiepin-d6 HCl (N,N-dimethyl-d6) (cis/trans mixture) 是 Dothiepin HCl 的氘代化合物。Dothiepin HCl 的 CAS 号为 25627-36-5。 |