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TMPY-04268
|
NUDC Protein, Human, Recombinant (His)
nudC nuclear distribution protein,MNUDC,HNUDC,NPD01...
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Human
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HEK293 Cells
|
|
NUDC (Nuclear Distribution C, Dynein Complex Regulator) is a Protein Coding gene. NUDC consists of at least 9 exons ranging from 66 bp to 266 bp in size and 8 introns from 92 bp to 2.0 kb in length, and the total genomic region spans about 8 kb. NUDC was mapped to 1p34-p35 by fluorescence in situ hybridization. This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. Nuclear migration is essential for the growth, development, and cellular function... |
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TMPY-03118
|
ORM2 Protein, Human, Recombinant (His)
AGP-B',ORM2,orosomucoid 2,AGP-B,AGP2
|
Human
|
HEK293 Cells
|
|
ORM2 belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. Lipocalins can be found in gram-negative bacteria, vertebrate cells, and invertebrate cells, and plants. They are associated with many biological processes. ORM2 functions as a transport protein in the bloodstream. It is expressed by the liver and s... |
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TMPY-01460
|
ABHD4 Protein, Human, Recombinant (His)
abhydrolase domain containing 4,ABH4
|
Human
|
Baculovirus Insect Cells
|
|
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipa... |
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TMPY-01736
|
COX-2 Protein, Human, Recombinant (His)
GRIPGHS,PHS-2,hCox-2,COX-2,PGHS-2,prostaglandin-endoperoxide...
|
Human
|
Baculovirus Insect Cells
|
|
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression ... |
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TMPH-00033
|
ASFV (strain Ba71V) p30 Protein (His)
Ba71V-93,Phosphoprotein p30,p30,CP204L,Phosphoprotein p32
|
ASFV
|
E. coli
|
|
Modifies the subcellular distribution of heterogeneous nuclear ribonucleoprotein K (HNRNPK) and may contribute to modulate HNRNPK functions related to processing and export of mRNAs during ASFV infection. |
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TMPK-00223
|
Ephrin B2/EFNB2 Protein, Human, Recombinant (hFc)
Ephrin B2,EFNB2,EPLG5,LERK5,HTKL
|
Human
|
HEK293 Cells
|
|
Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is highly distinct from its role in the endothelium. Ephrin-B2 is an important regulator of PDGFRβ endocytosis and thereby acts as a molecular switch controlling the downstream signaling activity of this receptor in mural cells. |
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TMPH-01752
|
Nestin/NES Protein, Human, Recombinant (His)
Nestin,NES
|
Human
|
P. pastoris (Yeast)
|
|
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. Nestin/NES Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 2... |
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TMPH-03090
|
SCP alpha chain Protein, Penaeus sp., Recombinant (His & Myc & SUMO)
Sarcoplasmic calcium-binding protein, alpha-B and -A chains
|
Penaeus
|
E. coli
|
|
Like parvalbumins, SCP's seem to be more abundant in fast contracting muscles, but no functional relationship can be established from this distribution. SCP alpha chain Protein, Penaeus sp., Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 42.0 kDa and the accession number is P02636. |
|
TMPK-01193
|
GPRC5D Protein-VLP, Mouse, Recombinant
MGC129713,orphan G-protein coupled receptor,GPRC5D,MGC129714
|
Mouse
|
HEK293 Cells
|
|
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. GPRC5D Protein-VLP, Mouse, R... |
|
TMPK-01236
|
APLN Protein, Human, Recombinant (hFc)
APJ endogenous ligand,Apelin,APEL
|
Human
|
HEK293 Cells
|
|
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized that APLN may perform its roles via modulation of macrophages. Additionally, due to the widespread distribution of the CVD, more effective therapeutic strategies need to be developed to overcome the related complications. APLN Protein, Human, Recombinant (hFc) is expressed in HE... |
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TMPY-02133
|
Carbonic Anhydrase VB Protein, Human, Recombinant (His)
carbonic anhydrase VB, mitochondrial,CA-VB,MGC39962
|
Human
|
E. coli
|
|
Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, kidney, placenta, lung, and skeletal muscle. It is not expressed in liver. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological process... |
|
TMPY-00587
|
GABARAP Protein, Human, Recombinant (His & MBP)
GABARAP-a,GABA(A) receptor-associated protein,ATG8A,MM46
|
Human
|
E. coli
|
|
The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in vivo by delaying cell death and its associated immune-related response. GABARAPs are uniquely required for antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. GABARAPs as the first known direct interaction partners of Nef that are essential... |
|
TMPJ-01291
|
CPNE1 Protein, Human, Recombinant (His)
CPNE1,CPN1,Copine I,Copine-1
|
Human
|
E. coli
|
|
Copine-1(CPNE1) encodes a calcium-dependent protein which belongs to the copine family. CPNE1contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, CPNE1 does not contain a predicted signal sequence or transmembrane domains. CPNE1 may regulate molecular events at the interface of the cell membrane and cytoplasm. CPNE1 has a broad tissue distribution and it may function in membrane trafficking. |
|
TMPK-01222
|
APLN Protein, Mouse, Recombinant (hFc)
APJ endogenous ligand,APEL,Apelin
|
Mouse
|
HEK293 Cells
|
|
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized that APLN may perform its roles via modulation of macrophages. Additionally, due to the widespread distribution of the CVD, more effective therapeutic strategies need to be developed to overcome the related complications. APLN Protein, Mouse, Recombinant (hFc) is expressed in HE... |
|
TMPK-00528
|
GPRC5D Protein-VLP, Cynomolgus, Recombinant
MGC129713,GPRC5D,MGC129714,orphan G-protein coupled receptor
|
Cynomolgus
|
HEK293 Cells
|
|
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. GPRC5D Protein-VLP, Cynomolg... |
|
TMPJ-00580
|
ZWINT Protein, Human, Recombinant (His)
ZWINT,ZW10 Interactor,Zwint-1,ZW10-Interacting Protein 1
|
Human
|
E. coli
|
|
ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex specifically during mitosis. ZWINT is a part of the MIS12 complex which is required for kinetochore formation and spindle checkpoint activity. In addition, ZWINT is required to target ZW10 to the kinetochore at prometaphase. |
|
TMPY-03604
|
VAMP3 Protein, Human, Recombinant (His)
vesicle-associated membrane protein 3,CEB
|
Human
|
E. coli
|
|
VAMP3, also known as cellubrevin, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. Because of VAMP3 gene's high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, VAMP3 was shown to be the human equivalent ... |
|
TMPY-02277
|
Carbonic Anhydrase 7 Protein, Human, Recombinant (His)
CAVII,carbonic anhydrase VII
|
Human
|
E. coli
|
|
Carbonic anhydrase 7, also known as carbonate dehydratase VII, carbonic anhydrase VII, CA-VII and CA7, is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, ... |
|
TMPK-00405
|
IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated
IL-7R-alpha,IL-7R,ILRA,IL-7R-α,IL-17RA,CANDF5,IL17R,CDw217,C...
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Human
|
HEK293 Cells
|
|
Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22. |
|
TMPY-04478
|
IP6K1/IHPK1 Protein, Human, Recombinant (His & GST)
inositol hexakisphosphate kinase 1,IHPK1,PiUS
|
Human
|
Baculovirus Insect Cells
|
|
IP6K1 (Inositol Hexakisphosphate Kinase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. IHPK1 is an inositol hexaphosphate kinase (IHPK) protein that belongs to the inositol phosphokinase (IPK) family. IHPK proteins are likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). IHPK1 may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth-suppressive and... |
|
TMPY-00471
|
INSL4 Protein, Human, Recombinant (His)
EPIL,insulin-like 4 (placenta),PLACENTIN
|
Human
|
HEK293 Cells
|
|
INSL4 (Insulin-Like 4) is a Protein Coding gene. An important paralog of this gene is RLN1. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains or just the A and B chains. INSL4 is a member of the insulin family, which includes insulin, IGF-I, IGF-II, relaxin, and INSL3.INSL4 distribution was tissue- and cell-specific. Indeed, INSL4 mRNA was most abundant in syncytiotrophoblas... |
|
TMPY-03456
|
SRFBP1 Protein, Human, Recombinant (His & GST)
STRAP,BUD22,P49,serum response factor binding protein 1,p49/...
|
Human
|
Baculovirus Insect Cells
|
|
SRFBP1 contains 7 WD repeats and belongs to the WD repeat STRAP family. SRFBP1 may play a role in the cellular distribution of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. SRFBP1 negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein. SRF... |
|
TMPY-00729
|
Cystatin D Protein, Human, Recombinant (His)
CST5,MGC71922,cystatin D
|
Human
|
HEK293 Cells
|
|
Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. As a member of type 2 cystatin, cystatin D is a single-domain protein and also has cysteine residues that form disulfide bridges. In contrast with the wider distribution of all the other family 2 cystatins, cystatin D is tissue-restricte... |
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TMPY-03969
|
SUSD4 Protein, Human, Recombinant (mFc)
sushi domain containing 4,PRO222
|
Human
|
HEK293 Cells
|
|
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical path... |
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TMPJ-01190
|
SPESP1 Protein, Human, Recombinant (His)
Sperm Equatorial Segment Protein 1,Glycosylated 38 kDa Sperm...
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Human
|
HEK293 Cells
|
|
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may intera... |
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TMPY-03280
|
RAMP3 Protein, Human, Recombinant (hFc)
receptor (G protein-coupled) activity modifying protein 3
|
Human
|
HEK293 Cells
|
|
RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution; high concentrations are found in the brain, lung, liver, heart and spleen with lower expression levels present in the testes, gastrointestinal tract and thyroid. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. They are required to transp... |
|
TMPY-00517
|
LSP1 Protein, Human, Recombinant (His)
lymphocyte-specific protein 1,WP34,pp52
|
Human
|
HEK293 Cells
|
|
LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. LSP1 is a lymphocyte-specific intracellular Ca2(+)-binding protein. LSP1 localizes to nascent phagocytic cups during Fcgamma receptor-mediated phagocytosis, where it displays the same ... |
|
TMPY-00261
|
Meprin beta Protein, Human, Recombinant (His)
meprin A, β,Meprin β,meprin A, beta
|
Human
|
HEK293 Cells
|
|
MEP1B (Meprin A Subunit Beta) is a Protein Coding gene. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in the kidney and intestine. Meprins are cell membrane, oligomeric metalloendopeptidases composed of two distinct but evolutionarily related subunits, alpha, and beta. MEP1A is mapped to the short arm of chromosome 6 by the use of radiation and som... |
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TMPY-01551
|
Serpin B8 Protein, Mouse, Recombinant (His)
CAP-2,serpin peptidase inhibitor, clade B (ovalbumin), membe...
|
Mouse
|
Baculovirus Insect Cells
|
|
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal... |
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TMPH-01524
|
KPNA1 Protein, Human, Recombinant (His)
Nucleoprotein interactor 1,SRP1-beta,Karyopherin subunit alp...
|
Human
|
E. coli
|
|
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta ... |
|
TMPY-02120
|
XPNPEP2 Protein, Human, Recombinant (His)
AEACEI,X-prolyl aminopeptidase (aminopeptidase P) 2, membran...
|
Human
|
HEK293 Cells
|
|
Aminopeptidase P (APP) is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. A membrane-bound and soluble form of this enzyme (XPNPEP2) have been identified as products of two separate genes. XPNPEP2, the X-linked gene that encodes membranous aminopeptidase P (APP), has been reported to associate with APP activity. The membrane aminopeptidase P (XPNPEP2) is largely limited in distribution ... |
|
TMPY-02132
|
LYPLA2 Protein, Human, Recombinant (His)
APT-2,lysophospholipase II,DJ886K2.4,APT2
|
Human
|
E. coli
|
|
Lysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family. This enzyme has lysophospholipase activity and may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acyl-protein thioesterase 1 (APT-1) and Acyl-protein thioesterase 2 (APT-2) are cytosolic lysophospholipids hydrolyzing enzymes. The serum activity of APT-1 may play an important role in the dete... |
|
TMPY-04411
|
YES1 Protein, Human, Recombinant (His & GST)
HsT441,c-yes,YES proto-oncogene 1, Src family tyrosine kinas...
|
Human
|
Baculovirus Insect Cells
|
|
Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 / c-Yes contains one protein kinase domain, one SH2 domain and one SH3 domain. It is thought that the subcellular distribution of Src-family tyrosine kinases, including c-Yes binding to the cellular membrane, is membranous and/or cytoplasmic. YES1 / c-Yes protein tyrosine kinase i... |
|
TMPY-01771
|
Latexin Protein, Mouse, Recombinant (His)
latexin
|
Mouse
|
E. coli
|
|
Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in the heart, prostate, ovary, kidney, pancreas, and colon. Latexin / LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional spe... |
|
TMPY-01412
|
Glypican 5 Protein, Human, Recombinant (His)
glypican 5
|
Human
|
Baculovirus Insect Cells
|
|
Glypican-5 (GPC5), is a cell membrane protein that belongs to the glypican family. The glypicans compose a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans that may play a role in the control of cell division and growth regulation. So far, six members (Glypican-1/GPC1, Glypican-2/GPC2, Glypican-3/GPC3, Glypican-4/GPC4, Glypican-5/GPC5, Glypican-6/GPC6) of this family are known in the vertebrates. In the adult, Glypican-5 is primarily expressed in the brain. It is als... |
|
TMPY-01734
|
CA13 Protein, Human, Recombinant (His)
carbonic anhydrase XIII,FLJ37995,CAXIII,MGC59868
|
Human
|
E. coli
|
|
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. The CAXIII is a member of th... |
|
TMPY-04828
|
TFF3 Protein, Human, Recombinant (His)
trefoil factor 3 (intestinal),ITF,P1B,TFI
|
Human
|
HEK293 Cells
|
|
Trefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Trefoil factor-3 (TFF3) is an estrogen-regulated gene associated with prognosis in different types of cancer. The presence and localization of TFF3 peptide was associated with the embryonic stage and tissue differentiation. TFF3 peptide distribution specific to the germ layers was not observed. The role of TFF3 peptide in cell migration and differentiation, immune response, an... |
|
TMPY-03986
|
PIST Protein, Human, Recombinant (His)
CAL,dJ94G16.2,golgi-associated PDZ and coiled-coil motif con...
|
Human
|
E. coli
|
|
GOPC, also known as PIST, interacts specifically with TC1 (a Rho-family small GTPase)] as a binding partner for Rhotekin. Rhotekin associates with PIST in vitro and both polarized and non-polarized MDCK (Madin-Darby canine kidney) cells. The C-terminal SPV (Ser-Pro-Val) motif of Rhotekin binds to the PDZ domain of PIST. The co-localization of PIST and Rhotekin at the Golgi apparatus can be detected in non-polarized fibroblast-like MDCK cells and AJs (adherens junctions) in the fully polarized ce... |
|
TMPY-02129
|
Transglutaminase 3/TGM3 Protein, Human, Recombinant (His)
transglutaminase 3,UHS2,TGE
|
Human
|
Baculovirus Insect Cells
|
|
Transglutaminases (TGase) are a family of calcium-dependent acyl-transfer enzymes ubiquitously expressed in mammalian cells and responsible for catalyzing covalent cross-links between proteins or peptides. Transglutaminase 3 (TGM3) is a member of a family of Ca2+-dependent enzymes that catalyze covalent cross-linking reactions between proteins or peptides. TGM3 isoform is widely expressed and is important for epithelial barrier formation. It is a zymogen, requiring proteolysis for activity. Calc... |
|
TMPY-02977
|
PDE1C Protein, Human, Recombinant (His & GST)
hCam-3,phosphodiesterase 1C, calmodulin-dependent 70kDa,cam-...
|
Human
|
Baculovirus Insect Cells
|
|
PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDEs are expressed ubiquitously, with each subtype having a s... |
|
TMPY-04567
|
SRPK1 Protein, Human, Recombinant (His & GST)
SRSF protein kinase 1,SFRSK1,RP3-422H11.1
|
Human
|
Baculovirus Insect Cells
|
|
Serine / threonine-protein kinase SRPK1, also known as SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1 and SRPK1, is a cytoplasm and nucleus protein that belongs to the protein kinase superfamily and CMGC Ser/Thr protein kinase family. Isoform 2 of SRPK1 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 of SRPK1 is only seen in th... |
|
TMPY-03728
|
CCL28 Protein, Human, Recombinant (His)
MEC,SCYA28,chemokine (C-C motif) ligand 28,CCK1
|
Human
|
E. coli
|
|
CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal surfaces and lactating mammary gland as well. Besides, CCL28 has been shown to exert a potent antimicrobial activity against both Gram-negative and Gram-positive bacteria and fungi. The potent antimicrobial function of CCL28 combined with its wide distribution in mucosal tissues an... |
|
TMPJ-01188
|
CORO6 Protein, Human, Recombinant (His)
Coronin-6,Clipin-E,CORO6
|
Human
|
E. coli
|
|
Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering via modulating the interaction between receptors and the actin cytoskeletal network. Coronins are a family of conserved actin-binding proteins originally identified in the actin-rich structure of the amoeba Dictyostelium discoideum . To date, seven members of coronins have been identified in mammals, and most exhibit tissue-specific distribution patterns. Coronin 6 is promin... |
|
TMPY-02025
|
CPLX2 Protein, Human, Recombinant (His)
CPX-2,Hfb1,921-L,complexin 2,CPX2
|
Human
|
E. coli
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Complexin-2 (CPLX2), a member of the complexin/synaphin family, is a soluble pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals. Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Complexins are unable to bind to monomeric SNARE proteins but bind with high affinity to ternary SNARE complexes and with lower affinity to target ... |
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TMPY-01679
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LCN1 Protein, Human, Recombinant (His)
TLC,MGC71975,TP,VEGP,Lipocalin 1,PMFA
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Human
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HEK293 Cells
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Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been fo... |
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TMPY-04813
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ACAT2 Protein, Rat, Recombinant (His)
acetyl-CoA acetyltransferase 2
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Rat
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E. coli
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Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two enzymes are involved in storing cholesteryl esters as lipid droplets, in macrophage foam-cell formation, in absorbing dietary cholesterol, and in supplying cholesteryl esters as part of the core lipid for lipoprotein synthesis and assembly. The key difference in tissue distributio... |
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TMPJ-00654
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LGALS8 Protein, Human, Recombinant
Prostate Carcinoma Tumor Antigen 1,Po66-CBP,Galectin-8,PCTA-...
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Human
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E. coli
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The Galectin family of proteins, with specificity for Nacetyllactosaminecontaining glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. Although they are localized primarily in the cytoplasm and lack a classical signal peptide, galectins can also be... |
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