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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37309 |
Diadenosine pentaphosphate pentaammonium
|
Others | Others |
Diadenosine pentaphosphate pentaammonium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, is one component of the diadenosine polyphosphates (ApnA, n=2-7) family. These compounds are found in secretory vesicles, including those in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes[1][2]. | |||
T41088 |
Diadenosine pentaphosphate pentalithium
|
Others | Others |
Diadenosine pentaphosphate pentalithium is an endogenous vasoactive purine dinucleotide, isolated from thrombocytes. It is a member of the diadenosine polyphosphates (ApnA, n=2–7) and is found in secretory vesicles of platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes. | |||
T37310 |
Diadenosine pentaphosphate pentasodium
|
Others | Others |
Diadenosine pentaphosphate pentasodium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, serves as a key component of secretory vesicles in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes. This compound, along with other diadenosine polyphosphates (ApnA, n=2-7), plays a crucial role in physiological processes[1][2]. | |||
T38382 |
8Br-HA
|
Others | Others |
8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT; IC50= 0.12 μM).1It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 μM, respectively). 1.Kawaguchi, M., Sekimoto, E., Ohta, Y., et al.Synthesis of fluorescent probes targeting tumor-suppressor protein FHIT and Identification of apoptosis-inducing FHIT inhibitorsJ. Med. Chem.64(13)9567-9576(2021) | |||
T63856 |
M1069
|
Others | Others |
M1069 是一种选择性的、口服具有活力的 A2A/A2B 型双腺苷受体拮抗剂,选择性比 A1、 A3亚型高 100 多倍。M1069 可拮抗腺苷引起的免疫抑制机制,表现出抗肿瘤作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02549 |
FHIT Protein, Mouse, Recombinant (His)
Adenylylsulfatase,Adenylylsulfate-ammonia adenylyltransferas... |
Mouse | E. coli |
Possesses dinucleoside triphosphate hydrolase activity. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Exhibits adenylylsulfatase activity, hydrolyzing adenosine 5'-phosphosulfate to yield AMP and sulfate. Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monop... |