Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T27150 |
Dersalazine sodium
UR12746,Dersalazine,UR 12746S (sodium salt),UR-12746S (sodium salt),UR-12746 |
Others | Others |
Dersalazine, a PAF antagonist and TNFα inhibitor, is used potentially for the treatment of ulcerative colitis. It showed anti-inflammatory effect in reactivated colitis in rats, as evidenced by a significant reduction in MPO activity. | |||
T70084 |
Dersalazine
Dersalazine Free Base |
IL Receptor; Platelet aggregation | Immunology/Inflammation; Others |
Dersalazine (Dersalazine Free Base) 是血小板活化因子抑制剂,通过下调 IL-17表达,在不同啮齿动物型结肠炎中发挥肠道抗炎活性,对溃疡性结肠炎患者具有潜在疗效。 |