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Search Results for " derivative "

Targets Recommended: Amino Acids and Derivatives Others

2952

抑制剂 & 化合物

357

天然产物

3

化合物库

5

重组蛋白

53

同位素标记化合物

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Cat. No.	Product Name
L6030	天然产物衍生物虚筛化合物库		163000 compounds
	16.3万种天然产物衍生物，并且在持续增加中；
NY1000	天然产物衍生物库		4000 compounds
	22个天然产物骨架，3745个天然产物衍生物；
L2800	5-羟色胺分子库		268 compounds
	268 种生物活性小分子化合物，用于高通量、高内涵筛选；

化合物库

天然产物衍生物虚筛化合物库

Cat.No: L6030

Compounds: 163000

天然产物衍生物库

Cat.No: NY1000

Compounds: 4000

5-羟色胺分子库

Cat.No: L2800

Compounds: 268

Cat. No.	Product Name	Target	Signaling Pathways
T13751	L-Threonine derivative-1	Others	Others
	L-Threonine derivative-1 是乙酰水杨酸-L-苏氨酸酯，具有潜在的镇痛活性。
T11550	Helioxanthin derivative 5-4-2 Helioxanthin 5-4-2	HBV	Microbiology/Virology
	Helioxanthin derivative 5-4-2 （Helioxanthin 5-4-2）是螺旋黄质的类似物，在体外显示出抗 HBV 活性，可用于研究HBV。
T11421	Glutaminase-IN-1 CB839 derivative	transporter	Metabolism
	Glutaminase-IN-1 (CB839 derivative)，是一种新型 1,3,4-硒二氮基肾型谷氨酰胺酶(KGA) 的变构抑制剂，在侵袭性 H22 肝癌异种移植模型中显示出抗肿瘤活性。
T12717	Basimglurant CTEP Derivative,RG7090	GluR	Neuroscience
	Basimglurant (CTEP Derivative) 是一种高效，选择性，可口服的 mGlu5负变构调节剂，Kd 值为1.1 nM。
T38506	cis-Clopidogrel-MP derivative cis-Clopidogrel-MP derivative,Clopidogrel-MP-AM	Others	Others
	cis-Clopidogrel-MP derivative, also known as Clopidogrel-MP-AM, is a 3’-methoxyacetophenone derivative of Clopidogrel active metabolite. This compound is an orally-active platelet inhibitor specifically targeting the P2Y12 receptor.
TP1154	Exendin-4 peptide derivative acetate GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS,Exendin-4 peptide derivative
	Exendin-4 peptide derivative acetate is an acetate salt of Exendin-4 peptide derivative.
T26397	6PGD-IN-S3 6PGD Inhibitor S3,S3,Danthron methyl derivative	Dehydrogenase	Metabolism
	6PGD-IN-S3 (6PGD Inhibitor S3) 是 6-磷酸葡萄糖酸脱氢酶 (6PGD) 的抑制剂。
T11249L	Dxd Exatecan derivative for ADC,OQM5SD32BQ,UNII-OQM5SD32BQ	Topoisomerase; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; DNA Damage/DNA Repair
	Dxd (OQM5SD32BQ) 是一种有效的DNA 拓扑异构酶 I 抑制剂，IC50值为 0.31 μM，用作HER2靶向ADC 的偶联药物。
T39320	Hemiasterlin derivative-1	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	Hemiasterlin Derivative-1, a derivative of hemiasterlin, is utilized in the synthesis of Antibody-Drug Conjugates (ADC).
T19296	DOTA derivative	Others	Others
	DOTA derivatives are phenoxy derivatives of cyclic Tosamide;Direct nitrification;It is more convenient to add nitro group after removing the protection of lithium aluminium hydride.
T40328	Betulinic acid derivative-1	Others	Others
	Betulinic acid derivative-1 demonstrates potent inhibition of osteoclast (OC) differentiation, achieving an IC50 value of 1.86 μM.
T13853	Pyridazinediones-derivative-1	Others	Others
	Pyridazinediones-derivative-1 has potential in treating neurodegenerative disorders.
T11654	Indirubin Derivative E804	Others	Others
	Indirubin Derivative E804 is an effective inhibitor of IGF1R, which has an IC50 value of 0.65.
T13570	Benzamide Derivative 1	Others	Others
	Benzamide Derivative 1 苯甲酰胺衍生物，具有胃动力学活性。Benzamide Derivative 1可用于研究胃肠疾病。
T13662	Diarylalkane derivative 1	Others	Others
	Diarylalkane derivative 1 is used for the research of pancreatitis.
T10106	3-arylisoquinolinamine derivative	Others	Others
	3-arylisoquinolinamine derivative is a compound with antitumor activity.
T13593	Heterocyclyl carbamate derivative 1	Others	Others
	Heterocyclyl carbamate derivative 1, a heterocyclyl carbamate derivative, is used for the research of neurological diseases and inflammatory.
T19534	Glycerol derivative 1	Others	Others
	Glycerol derivative 1 is a Glycerol derivative.
TP1392	Exendin derivative 1
	Exendin derivative 1 is a 39 amino acid peptide.
TP1161	Exendin-4 peptide derivative FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
	FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.Exendin-4 peptide derivatives are structurally derived from Exendin-4 and may relates to dual GLP-1/glucagon receptor agonists.
TP1387	Cyclosporin A-Derivative 2
	Derivative 2 is A novel Derivative of Cyclosporin A.Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin.
T19495	Oleanolic acid derivative 2	Others	Others
	Oleanolic acid derivative 2 is an oleanolic acid derivative.
T19494	Oleanolic acid derivative 1	Others	Others
	Oleanolic acid derivative 1 is an oleanolic acid derivative.
T19170	Carbazole derivative 1 2-Fluoro-7-[(3-pyridinyl)methyl]-9H-carbazole	Others	Others
	Carbazole derivative 1 is used to reduce androgen or oestrogen levels in mammals.
TP1845	Cyclosporin A-Derivative 1
	Cyclosporin A-Derivative 1 is a crystalline intermediate derived from the opening of cyclosporin A.
T12333	OT antagonist 1 demethyl derivative	Others	Others
	OT antagonist 1 demethyl derivative is the demethyl derivative of OT antagonist 1. OT antagonist 1 is a selective Oxytocin antagonist (Ki of 50 nM. )
TP1524	AGA-(C8R) HNG17, Humanin derivative
	This peptide is a potent humanin (HN) derivative. It completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.
T10016	Hydrocarbon chain derivative 1 6,6'-Oxybis[2,2-dimethyl-1-hexanol]	Others	Others
	Hydrocarbon chain derivative 1 has inhibitory activities against lipid synthesis.
TP1405	Cyclosporin A-Derivative 1 Free base
	Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A.
T84474	13(R),14(R)-epoxy Fluprostenol isopropyl ester Epoxy Derivative 1	Others	Others
	Fluprostenol isopropyl ester, a potent agonist of the F-series prostaglandin receptor, serves as a prodrug utilized clinically as an ocular hypotensive agent for glaucoma treatment. An impurity, 13(R),14(R)-epoxy fluprostenol isopropyl ester, arises during its production, existing as a chiral enantiomer of the epoxide. The pharmacological properties of this specific enantiomer have yet to be thoroughly investigated.
T84503	15-PGDH-IN-2 Thiazolidinedione derivative	Others	Others
	15-PGDH-IN-2（Compound 2）是一种具有0.274 nM IC50值的15-PGDH抑制剂，适用于脱发、骨形成、胃溃疡以及皮肤伤口愈合的研究。
T34189	PTZ-256 phenothiazine derivative,PTZ256	Others	Others
	PTZ-256 is a phenothiazine derivative with chemical name: 3-(10H-phenothiazin-10-yl)propane-1-amine. PTZ-256 has molecule weight 256, therefore, we call it as PTZ-256.
T81977	Kobusine derivative-1	Others	Others
	Kobusine derivative-1，一种Kobusine衍生物，展现出了对癌细胞显著的抗增殖活性。
T72411	Kobusine derivative-2	Others	Others
	Kobusine derivative-2，一种kobusine衍生物，对癌细胞显示出抗增殖活性，并能诱导MDA-MB-231细胞在亚G1期阻滞，表现出抗癌活性。
T13610	Chol-5-en-24-al-3β-ol Vitamin D3 derivative	Others	Others
	Chol-5-en-24-al-3β-ol is a steroid compound.
T76220	Cyclosporin A-Derivative 3
	Cyclosporin A-Derivative 3 是 Cyclosporin A 的衍生物，具有钙调神经磷酸酶抑制作用。
T34911	TPT-172 HCl (R33) TPT 172,TPT172,TPT-172,thiophene thiourea derivative. R33	Others	Others
	TPT-172, also known as R33 (described in Mecozzi et al' s paper), is a thiophene thiourea derivative with molecule weight 172 in free base form. There is no formal name yet, we temporally call this molecule as TPT-172. Please also see similar products: TP
T9048	Ecamsule	Others	Others
	Ecamsule 是一种亚苄基樟脑衍生物，其中许多以其出色的光稳定性而闻名。可添加到防晒霜中以过滤掉 UVA 射线。
T9062	CA77.1	Autophagy	Autophagy
	CA77.1 是一种新型伴侣介导的自噬激活剂，用于治疗阿尔茨海默病。它是 AR7 的衍生物，可以增加溶酶体受体在溶酶体中的表达。
T8767	PfDHODH-IN-2	Dehydrogenase; Parasite	Metabolism; Microbiology/Virology
	PfDHODH-IN-2 是一种二氢噻吩酮衍生物，是一种有效的恶性疟原虫二氢乳清酸脱氢酶抑制剂，其IC50值为 1.11 µM。它具有抗疟作用，可研究疟疾。
T28467	PSMA617-TCMC TFA PSMA617-TCMC TFA salt,PSMA617-analog, PSMA617-derivative with TCMC,PSMA-617-TCMC	Others	Others
	PSMA617-TCMC is a derivative of PSMA-617 with structure modification, in which the caroboxy groups in DOTA ring is replaced by TCMC macrocycle. PSMA-617 is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer.
T11991	Mefentrifluconazole	P450; Antifungal	Metabolism; Microbiology/Virology
	Mefentrifluconazole 是一种有效的、选择性的和具有口服活性的真菌 CYP51 (Kd= 0.5 nM) 抑制剂，但对人芳香酶的抑制活性较低，IC50值为0.92 μM。它是一种新型唑类衍生物，用作农用广谱抗真菌剂。
T1481	Fudosteine 福多司坦,福多斯坦	Others	Others
	Fudosteine 是一种半胱氨酸衍生物和粘液活性剂。它能够抑制 MUC5AC 基因表达，阻碍 MUC5AC 粘蛋白过度分泌。
T8880	PFM01	Others	Others
	PFM01 是 MRE11核酸内切酶抑制剂，是 N-烷基化的 Mirin 衍生物。它可以通过非同源末端连接 (NHEJ) 和同源重组 (HR) 调节双链断裂修复 (DSBR)。
T6594	MNS	Syk; Src; p97	Angiogenesis; Tyrosine Kinase/Adaptors; Ubiquitination
	MNS 是一种酪氨酸激酶抑制剂和广谱抗血小板药物，是一种 β-硝基苯乙烯衍生物。它完全抑制 U46619 (IC50:2.1 μM)、ADP (IC50:4.1 μM)、花生四烯酸 (IC50:5.8 μM)、胶原 (IC50:7.0 μM)和凝血酶 (IC50:12.7 μM)诱导的血小板聚集，并抑制 Src (IC50:27.3 μM)、Syk (IC50:2.8 μM) 和 FAK (IC50:97.6 μM)。
T9723	GluR6 antagonist-1	Src	Angiogenesis; Tyrosine Kinase/Adaptors
	GluR6 antagonist-1 抑制酪氨酸激酶 p56lck SH2 结构域的 pY 结合位点。
T16706	Quinoclamine 灭藻醌,2-氨基-3-氯-1,4-萘醌	NF-κB	NF-κB
	Quinoclamine 是一种 NF-κB 抑制剂，是一种萘醌衍生物，具有抗肿瘤活性。
T8543	KN-92 hydrochloride	CaMK	Neuroscience
	KN-92 hydrochloride 是 KN-93 的非活性衍生物，对 CaM 激酶无抑制作用。它可作为对照化合物用于阐明 KN-93 的拮抗活性。KN-93 是一种可渗透细胞的、可逆的、竞争性的 CaMKII 抑制剂。
T1307	Carmofur HCFU,卡莫氟	Nucleoside Antimetabolite/Analog; Virus Protease; SARS-CoV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Carmofur (HCFU) 是 5-氟尿嘧啶的衍生物，是一种抗肿瘤药物。它是一种酸性神经酰胺酶抑制剂，用于治疗乳腺癌和结直肠癌。它抑制 SARS-CoV-2主要蛋白酶，还抑制 Vero E6 细胞 SARS-CoV-2，EC50为 24.3 μM。
T19857	Glyphosate Atila,Lancer,Folusen,草甘膦	Apoptosis; Autophagy	Apoptosis; Autophagy
	Glyphosate (Atila) 是氨基酸甘氨酸的衍生物。它是一种除草剂，靶向并阻断植物合成芳香氨基酸所必需的莽草酸途径。

化合物

L-Threonine derivative-1

Cat.No: T13751

Target: Others

Helioxanthin derivative 5-4-2

Cat.No: T11550

Synonym: Helioxanthin 5-4-2

Target: HBV

Glutaminase-IN-1

Cat.No: T11421

Synonym: CB839 derivative

Target: transporter

Cat.No: T12717

Synonym: CTEP Derivative,RG7090

Target: GluR

cis-Clopidogrel-MP derivative

Cat.No: T38506

Synonym: cis-Clopidogrel-MP derivative,Clopidogrel-MP-AM

Target: Others

Exendin-4 peptide derivative acetate

Cat.No: TP1154

Synonym: GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS,Exendin-4 peptide derivative

Cat.No: T26397

Synonym: 6PGD Inhibitor S3,S3,Danthron methyl derivative

Target: Dehydrogenase

Cat.No: T11249L

Synonym: Exatecan derivative for ADC,OQM5SD32BQ,UNII-OQM5SD32BQ

Target: Topoisomerase, ADC Cytotoxin

Hemiasterlin derivative-1

Cat.No: T39320

Target: Others, ADC Cytotoxin

DOTA derivative

Cat.No: T19296

Target: Others

Betulinic acid derivative-1

Cat.No: T40328

Target: Others

Pyridazinediones-derivative-1

Cat.No: T13853

Target: Others

Indirubin Derivative E804

Cat.No: T11654

Target: Others

Benzamide Derivative 1

Cat.No: T13570

Target: Others

Diarylalkane derivative 1

Cat.No: T13662

Target: Others

3-arylisoquinolinamine derivative

Cat.No: T10106

Target: Others

Heterocyclyl carbamate derivative 1

Cat.No: T13593

Target: Others

Glycerol derivative 1

Cat.No: T19534

Target: Others

Exendin derivative 1

Cat.No: TP1392

Exendin-4 peptide derivative

Cat.No: TP1161

Synonym: FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS

Cyclosporin A-Derivative 2

Cat.No: TP1387

Oleanolic acid derivative 2

Cat.No: T19495

Target: Others

Oleanolic acid derivative 1

Cat.No: T19494

Target: Others

Carbazole derivative 1

Cat.No: T19170

Synonym: 2-Fluoro-7-[(3-pyridinyl)methyl]-9H-carbazole

Target: Others

Cyclosporin A-Derivative 1

Cat.No: TP1845

OT antagonist 1 demethyl derivative

Cat.No: T12333

Target: Others

AGA-(C8R) HNG17, Humanin derivative

Cat.No: TP1524

Hydrocarbon chain derivative 1

Cat.No: T10016

Synonym: 6,6'-Oxybis[2,2-dimethyl-1-hexanol]

Target: Others

Cyclosporin A-Derivative 1 Free base

Cat.No: TP1405

13(R),14(R)-epoxy Fluprostenol isopropyl ester

Cat.No: T84474

Synonym: Epoxy Derivative 1

Target: Others

Cat.No: T84503

Synonym: Thiazolidinedione derivative

Target: Others

Cat.No: T34189

Synonym: phenothiazine derivative,PTZ256

Target: Others

Kobusine derivative-1

Cat.No: T81977

Target: Others

Kobusine derivative-2

Cat.No: T72411

Target: Others

Chol-5-en-24-al-3β-ol

Cat.No: T13610

Synonym: Vitamin D3 derivative

Target: Others

Cyclosporin A-Derivative 3

Cat.No: T76220

TPT-172 HCl (R33)

Cat.No: T34911

Synonym: TPT 172,TPT172,TPT-172,thiophene thiourea derivative. R33

Target: Others

Cat.No: T9048

Target: Others

Cat.No: T9062

Target: Autophagy

Cat.No: T8767

Target: Dehydrogenase, Parasite

PSMA617-TCMC TFA

Cat.No: T28467

Synonym: PSMA617-TCMC TFA salt,PSMA617-analog, PSMA617-derivative with TCMC,PSMA-617-TCMC

Target: Others

Mefentrifluconazole

Cat.No: T11991

Target: P450, Antifungal

Cat.No: T1481

Synonym: 福多司坦,福多斯坦

Target: Others

Cat.No: T8880

Target: Others

Cat.No: T6594

Target: Syk, Src, p97

GluR6 antagonist-1

Cat.No: T9723

Target: Src

Cat.No: T16706

Synonym: 灭藻醌,2-氨基-3-氯-1,4-萘醌

Target: NF-κB

KN-92 hydrochloride

Cat.No: T8543

Target: CaMK

Cat.No: T1307

Synonym: HCFU,卡莫氟

Target: Nucleoside Antimetabolite/Analog, Virus Protease, SARS-CoV, DNA/RNA Synthesis

Cat.No: T19857

Synonym: Atila,Lancer,Folusen,草甘膦

Target: Apoptosis, Autophagy

Cat. No.	Product Name	Target	Signaling Pathways
T82896	Benzylbenzofuran derivative-1
	Benzylbenzofuran derivative-1 (Compound 8)是从Silene conoidea中分离的一种苯甲酰基苯并呋喃衍生物。
T8254	Chrysoobtusin	Others	Others
	Chrysoobtusin 是一种蒽醌衍生物，分离自决明子。其中决明子具有保肝、通便、明目的作用。
T8087	Tropolone	Tyrosinase	Proteases/Proteasome
	Tropolone 是一种 mushroom tyrosinase 抑制剂，IC50=0.4 μM，它的抑制作用可以通过透析或过量的 CU2+逆转。它是 2 位上带有羟基的 tropone 衍生物，是许多 Azulene 衍生物的前体，如 2-methylazulene-1-carboxylate。
T9057	norbergenin	IL Receptor; TNF; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	Norbergenin 是一种 bergenin 的邻去甲基衍生物，可从白芍的根茎中分离得到，具有中等的抗氧化活性。
TN1899	Lycoramine	AChE	Neuroscience
	Lycoramine 是一种加兰他敏的二氢衍生物，从Lycoris radiate 中分离得到，是一种乙酰胆碱酯酶抑制剂。
TN1546	Dactylorhin A	NO Synthase	Immunology/Inflammation
	Dactylorhin A 是一种琥珀酸衍生物酯，分离自 Gymnadenia conopsea 根茎中。它对 RAW 264.7 巨噬细胞产生 NO 有中等程度的抑制作用。
TN1149	6''-O-acetylsaikosaponin A	Others	Others
	6''-O-Acetylsaikosaponin A 是一种分离自柴胡根中的乙酰柴胡皂苷，表现出一定的破骨细胞抑制活性。
TN7060	Methyl oleanonate	PPAR	DNA Damage/DNA Repair; Metabolism
	Methyl oleanonate 是从柃木中分离得到的一种三萜类天然产物，是齐墩果酸衍生物，是一种PPARγ激动剂，具有抗癌作用。
T12045	(-)-Hydroxycitric acid lactone 藤黄内酯,Garcinia lactone	ATP Citrate Lyase	Metabolism
	(-)-Hydroxycitric acid lactone (Garcinia lactone) 是一种有效的 ATP-柠檬酸裂解酶抑制剂，能够催化柠檬酸盐线粒体外裂解为草酰乙酸和乙酰辅酶 A，限制了脂肪酸合成所需乙酰辅酶 A 单位的可用性。它是一种减肥药，是一种广受欢迎的减肥食品补充剂。
T19720	Colcemid C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine	Microtubule Associated	Cytoskeletal Signaling
	Colcemid (NSC-3096) 是一种微管聚合抑制剂，可诱导细胞凋亡，可用于肿瘤和胚胎克隆的研究。
T4116	S-Adenosyl-DL-Methionine Ademetionine,S-腺苷蛋氨酸,S-ADENOSYL-L-METHIONINE	Others	Others
	S-Adenosyl-DL-Methionine (Ademetionine) 是一种 Ademetionine 的衍生物。其中Ademetionine 是蛋氨酸的中间代谢产物。
T2185	L-Ascorbic acid 2-phosphate trisodium L-抗坏血酸-2-磷酸三钠盐（维生素C）,L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐	Reactive Oxygen Species; c-Met/HGFR; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB; Tyrosine Kinase/Adaptors
	L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) 是长效的维生素 C 衍生物，能够刺激胶原蛋白的表达和形成。Sodium L-ascorbyl-2-phosphate 提高成骨细胞分化过程中 hASC 中的碱性磷酸酶活性和 runx2A 的表达，因此，能够促进人脂肪干细胞的成骨分化。
T15138	DL-Dopa	Endogenous Metabolite	Metabolism
	DL-Dopa 是一种苯丙氨酸 β-羟基化衍生物。
T5S2350	Beta-Acetoxyisovalerylshikonin 乙酰氧基异戊酰阿卡宁,Acetoxyisovalerylalkannin,β-乙酰氧基异戊酰阿卡宁	Others	Others
	Acetoxyisovalerylshikonin 是一种萘醌衍生物，提取自Arnebia euchroma 中。
TJS0312	7-hydroxy-4-methyl-8-nitrocoumarin	Others	Others
	7-Hydroxy-4-methyl-8-nitrocoumarin 是香豆素衍生物的一种。
TN7122	Micromarin F E-Methylarnottinin,5'-hydroxylosthole	Others	Others
	Micromarin F (E-Methylarnottinin) 是从 Micromelum minutum Wight et Arn 的茎中提取的香豆素衍生物。
T4952	9-Hydroxycamptothecin 9-HCPT,9-羟基喜树碱,10-Hydroxycampothecin	Topoisomerase	DNA Damage/DNA Repair
	9-Hydroxycampothecin 是具有抗癌活性的喜树碱衍生物。
T2O2770	Agarotetrol	Others	Others
	Agarotetrol 是一种色酮衍生物，从沉香中分离得到。
TN5746	Gnetifolin E 买麻藤戊素	Others	Others
	Gnetifolin E 是一种新的白藜芦醇三聚体衍生物，来自 Gnetum brunonianum。
T0938	Thiabendazole 2-(4-Thiazolyl)benzimidazole,噻菌灵	Microtubule Associated; Mitochondrial Metabolism; Parasite	Cytoskeletal Signaling; Metabolism; Microbiology/Virology
	Thiabendazole (2-(4-Thiazolyl)benzimidazole) 是具有驱虫特性的苯并咪唑衍生物。
T40370	2′-Deoxyadenosine 5′-monophosphate disodium	Endogenous Metabolite	Metabolism
	2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.
T8101	Nepsilon-Acetyl-L-lysine	Others; Endogenous Metabolite	Metabolism; Others
	Nepsilon-Acetyl-L-lysine 是一种氨基酸赖氨酸衍生物。
TN7123	Enmein, 13-deoxy-19-hydroxy-, (19R)-	Others	Others
	Enmein, 13-deoxy-19-hydroxy-, (19R)- 是 Enmein 型二萜衍生物，可用于抗肿瘤药物的制备。
T0543	7-Methylxanthine Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤	Nucleoside Antimetabolite/Analog; Endogenous Metabolite; Adenosine Receptor	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	7-Methylxanthine 是一种黄嘌呤的甲基衍生物，是人尿结石的嘌呤成分。7-Methylxanthine 对腺苷受体有亲和力。
T1151	Roxithromycin Roxl-150,罗红霉素,RU-28965	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Roxithromycin (RU-28965) 是半合成的大环内酯类抗生素。
T2977	Vanillin acetate Acetovanillin,乙酰香兰酯,Acetylvanillin,4-Formyl-2-methoxyphenyl acetate,乙酰香兰素,4-Acetoxy-3-methoxybenzaldehyde	Others	Others
	Acetylvanillin 可由香草醛用乙酸酐处理后得到。
T0444	Econazole (±)-Econazol,益康唑	Antibiotic; Antifection; Antifungal	Microbiology/Virology
	Econazole ((±)-Econazol) 是一种咪唑衍生物，是一种抗真菌剂。
TN6773	Acetoxyvalerensre acetylvalerenolic acid	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Acetoxyvalerensre (acetylvalerenolic acid) 是缬草酸的衍生物，它是一种 GABAA 受体调节剂。
T10886	Crocetine dimethyl ester Dimethylcrocetin	Antioxidant	oxidation-reduction
	Crocetine dimethyl ester (Dimethylcrocetin) 是一种藏红花素衍生物，具有抗氧化活性，抑制 AChE 活性，抑制细胞生长分化。
T8281	(R)-Sulforaphane L-Sulforaphane,(R)-1-异硫氰酰-4-(甲基亚磺酰)丁烷	Nrf2	Immunology/Inflammation
	L-Sulforaphane 是高效的Keap1/Nrf2/ARE途径诱导剂。与 S-异构体相比，它对大鼠肝脏和肺部的致癌解毒酶系统的诱导能力更强。
TN7051	2,4-Dihydroxybenzaldehyde 2,4-二羟基苯甲醛,4-Formylresorcinol,beta-Resorcylaldehyde,4-Hydroxysalicylaldehyde	Endogenous Metabolite	Metabolism
	2,4-Dihydroxybenzaldehyde (4-Formylresorcinol) 是内源性代谢产物的一种。
T8021	Dibenzoyl Thiamine Bentiamine,二苯甲酰硫胺素	Others	Others
	Dibenzoyl Thiamine (Bentiamine) 是一种硫胺素的衍生物。它在体内被迅速吸收，并转化成硫胺素。
T1262	Tazobactam Tazobactamum,Tazobactam acid,他唑巴坦酸,YTR-830H,CL-298741,他唑巴坦	Antibacterial; Antibiotic	Microbiology/Virology
	Tazobactam (YTR-830H) acid 是一种具有抗菌活性的β-内酰胺酶抑制剂。
TN7066	Coryneine 2-(3,4-dihydroxyphenyl)ethyl-trimethylazanium,Quaternary dopamine,Trimethyl(3,4-dihydroxyphenethyl)aminium,棍掌碱,Dopamine methiodide	Others	Others
	Coryneine (Trimethyl(3,4-dihydroxyphenethyl)aminium) 是从附子根中提取的多巴胺的季铵衍生物。
PDK0015	4-Hydroxycoumarin	Endogenous Metabolite; Antibacterial; AChR	Metabolism; Microbiology/Virology; Neuroscience
	4-Hydroxycoumarin 是香豆素衍生物，也是通用的杂环支架之一，具有亲电和亲核性质。
T2217	Cephalomannine Baccatin III,三尖杉宁碱	Microtubule Associated	Cytoskeletal Signaling
	Cephalomannine (Baccatin III) 是一种从云南红豆杉中提取的紫杉醇衍生物，具有抗肿瘤活性，可用于癌症研究。
T5986	3-Hydroxypicolinic acid 3-羟基-2-吡啶甲酸,Picolinic acid, 3-hydroxy- (6CI,7CI,8CI),2-Carboxy-3-hydroxypyridine	Endogenous Metabolite	Metabolism
	3-Hydroxypicolinic acid (Picolinic acid, 3-hydroxy- (6CI,7CI,8CI)) 是一种内源性代谢物，属于吡啶甲酸的衍生物。
T4109	Rhapontigenin 3'-O-glucoside 丹叶大黄素 3'-O-葡萄糖苷,丹叶大黄素-3'-O-葡萄糖苷	Others; P450	Metabolism; Others
	Rhapontigenin 3'-O-glucoside 是一种 Rhapontigenin 的衍生物，是 P450 1A1 抑制剂，可用于预防癌症。
T6780	Benzamide Amid kyseliny benzoove,苯甲酰胺,Phenylcarboxyamide,Benzoylamide	PARP; Endogenous Metabolite	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Benzamide (Amid kyseliny benzoove) 是聚(ADP-核糖)聚合酶的抑制剂，是苯甲酸的衍生物。
T21367	Tetrahydrofolic acid 5,6,7,8-tetrahydrofolic acid,folate-H4,Tetrahydropteroylglutamic acid,th-folate	Endogenous Metabolite	Metabolism
	Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) 是一种维生素 B9 衍生物，是生物体常见的一碳供体，参与生物体生长代谢。
TN3396	Alpinumisoflavone acetate 4'-O-Acetylalpinumisoflavone	Others	Others
	Alpinumisoflavone acetate (4'-O-Acetylalpinumisoflavone) 是一种新的alpinumisoflavone 衍生物。Alpinumisoflavone 在0.63 ug/disc 时强烈抑制生殖管生长。
TN1643	Ferulamide 4-Hydroxy-3-methoxycinnamide,阿魏酸酰胺	PAFR; AChR	GPCR/G Protein; Neuroscience
	Ferulamide (4-Hydroxy-3-methoxycinnamide) 是从巴豆中分离的阿魏酸衍生物，具有抗胆碱酯酶活性。
T0814	Ampicillin Trihydrate NCI-C56086,氨苄青霉素三水合物	Antibacterial; Antibiotic	Microbiology/Virology
	Ampicillin Trihydrate (NCI-C56086) 是一种 β-内酰胺类广谱抗生素，可对抗多种革兰氏阳性和革兰氏阴性细菌。
T5S0836	Isoastragaloside II 黄芪甲苷VII,Astrasieversianin VII	Others	Others
	Isoastragaloside II (Astrasieversianin VII) 是一种是从黄芪毛状根培养分离得到的黄芪甲苷。
T2807	Caffeic Acid	Lipoxygenase; Endogenous Metabolite; TRP/TRPV Channel	Membrane transporter/Ion channel; Metabolism
	Caffeic acid 是5-脂氧合酶和 TRPV1离子通道的双重抑制剂。
T16747	Riboflavin Tetrabutyrate	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Riboflavin Tetrabutyrate 是一种亲脂性黄素衍生物，具有抗氧化和脂质过氧化物去除活性。
TN7048	3-O-p-Coumaroylquinic acid	Others	Others
	3-O-p-Coumaroylquinic acid 是羟基肉桂酸衍生物，从 70% 甲醇山楂提取物 (Crataegi folium cum flore) 中分离得到。
TMS0719	Sequoyitol 5-O-Methyl-Myo-Inositol,红杉醇,红杉醇,西曲依醇	Others	Others
	Sequoyitol (5-O-Methyl-Myo-Inositol) 来源于植物。它可以改善体内葡萄糖耐量，降低血糖，可用于糖尿病的研究。
TN1419	Rhamnetin beta-Rhamnocitrin,鼠李素	Others; Phospholipase	Metabolism; Others
	Rhamnetin (beta-Rhamnocitrin) 是一种槲皮素衍生物，在芫荽中被发现，具有抗氧化和抗炎活性。Rhamnetin 可抑制分泌型磷脂酶 A2。
T1310	2-Thiouracil Thiouracil,硫代由雪,Deracil,2-硫脲嘧啶	Thyroid hormone receptor(THR); NO Synthase	Endocrinology/Hormones; Immunology/Inflammation
	2-Thiouracil (Deracil) 是神经型一氧化氮合酶 (nNOS) 的选择性抑制剂(Ki:20 μM)，是一种抗甲状腺化合物，可用作高度特异性的黑色素瘤探测物。
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天然产物

Benzylbenzofuran derivative-1

Cat.No: T82896

Cat.No: T8254

Target: Others

Cat.No: T8087

Target: Tyrosinase

Cat.No: T9057

Target: IL Receptor, TNF, Reactive Oxygen Species

Cat.No: TN1899

Target: AChE

Cat.No: TN1546

Target: NO Synthase

6''-O-acetylsaikosaponin A

Cat.No: TN1149

Target: Others

Methyl oleanonate

Cat.No: TN7060

Target: PPAR

(-)-Hydroxycitric acid lactone

Cat.No: T12045

Synonym: 藤黄内酯,Garcinia lactone

Target: ATP Citrate Lyase

Cat.No: T19720

Synonym: C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine

Target: Microtubule Associated

S-Adenosyl-DL-Methionine

Cat.No: T4116

Synonym: Ademetionine,S-腺苷蛋氨酸,S-ADENOSYL-L-METHIONINE

Target: Others

L-Ascorbic acid 2-phosphate trisodium

Cat.No: T2185

Synonym: L-抗坏血酸-2-磷酸三钠盐（维生素C）,L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐

Target: Reactive Oxygen Species, c-Met/HGFR, Endogenous Metabolite

Cat.No: T15138

Target: Endogenous Metabolite

Beta-Acetoxyisovalerylshikonin

Cat.No: T5S2350

Synonym: 乙酰氧基异戊酰阿卡宁,Acetoxyisovalerylalkannin,β-乙酰氧基异戊酰阿卡宁

Target: Others

7-hydroxy-4-methyl-8-nitrocoumarin

Cat.No: TJS0312

Target: Others

Cat.No: TN7122

Synonym: E-Methylarnottinin,5'-hydroxylosthole

Target: Others

9-Hydroxycamptothecin

Cat.No: T4952

Synonym: 9-HCPT,9-羟基喜树碱,10-Hydroxycampothecin

Target: Topoisomerase

Cat.No: T2O2770

Target: Others

Cat.No: TN5746

Synonym: 买麻藤戊素

Target: Others

Cat.No: T0938

Synonym: 2-(4-Thiazolyl)benzimidazole,噻菌灵

Target: Microtubule Associated, Mitochondrial Metabolism, Parasite

2′-Deoxyadenosine 5′-monophosphate disodium

Cat.No: T40370

Target: Endogenous Metabolite

Nepsilon-Acetyl-L-lysine

Cat.No: T8101

Target: Others, Endogenous Metabolite

Enmein, 13-deoxy-19-hydroxy-, (19R)-

Cat.No: TN7123

Target: Others

7-Methylxanthine

Cat.No: T0543

Synonym: Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Adenosine Receptor

Cat.No: T1151

Synonym: Roxl-150,罗红霉素,RU-28965

Target: ribosome, Antibacterial, Antibiotic

Vanillin acetate

Cat.No: T2977

Synonym: Acetovanillin,乙酰香兰酯,Acetylvanillin,4-Formyl-2-methoxyphenyl acetate,乙酰香兰素,4-Acetoxy-3-methoxybenzaldehyde

Target: Others

Cat.No: T0444

Synonym: (±)-Econazol,益康唑

Target: Antibiotic, Antifection, Antifungal

Acetoxyvalerensre

Cat.No: TN6773

Synonym: acetylvalerenolic acid

Target: GABA Receptor

Crocetine dimethyl ester

Cat.No: T10886

Synonym: Dimethylcrocetin

Target: Antioxidant

(R)-Sulforaphane

Cat.No: T8281

Synonym: L-Sulforaphane,(R)-1-异硫氰酰-4-(甲基亚磺酰)丁烷

Target: Nrf2

2,4-Dihydroxybenzaldehyde

Cat.No: TN7051

Synonym: 2,4-二羟基苯甲醛,4-Formylresorcinol,beta-Resorcylaldehyde,4-Hydroxysalicylaldehyde

Target: Endogenous Metabolite

Dibenzoyl Thiamine

Cat.No: T8021

Synonym: Bentiamine,二苯甲酰硫胺素

Target: Others

Cat.No: T1262

Synonym: Tazobactamum,Tazobactam acid,他唑巴坦酸,YTR-830H,CL-298741,他唑巴坦

Target: Antibacterial, Antibiotic

Cat.No: TN7066

Synonym: 2-(3,4-dihydroxyphenyl)ethyl-trimethylazanium,Quaternary dopamine,Trimethyl(3,4-dihydroxyphenethyl)aminium,棍掌碱,Dopamine methiodide

Target: Others

4-Hydroxycoumarin

Cat.No: PDK0015

Target: Endogenous Metabolite, Antibacterial, AChR

Cat.No: T2217

Synonym: Baccatin III,三尖杉宁碱

Target: Microtubule Associated

3-Hydroxypicolinic acid

Cat.No: T5986

Synonym: 3-羟基-2-吡啶甲酸,Picolinic acid, 3-hydroxy- (6CI,7CI,8CI),2-Carboxy-3-hydroxypyridine

Target: Endogenous Metabolite

Rhapontigenin 3'-O-glucoside

Cat.No: T4109

Synonym: 丹叶大黄素 3'-O-葡萄糖苷,丹叶大黄素-3'-O-葡萄糖苷

Target: Others, P450

Cat.No: T6780

Synonym: Amid kyseliny benzoove,苯甲酰胺,Phenylcarboxyamide,Benzoylamide

Target: PARP, Endogenous Metabolite

Tetrahydrofolic acid

Cat.No: T21367

Synonym: 5,6,7,8-tetrahydrofolic acid,folate-H4,Tetrahydropteroylglutamic acid,th-folate

Target: Endogenous Metabolite

Alpinumisoflavone acetate

Cat.No: TN3396

Synonym: 4'-O-Acetylalpinumisoflavone

Target: Others

Cat.No: TN1643

Synonym: 4-Hydroxy-3-methoxycinnamide,阿魏酸酰胺

Target: PAFR, AChR

Ampicillin Trihydrate

Cat.No: T0814

Synonym: NCI-C56086,氨苄青霉素三水合物

Target: Antibacterial, Antibiotic

Isoastragaloside II

Cat.No: T5S0836

Synonym: 黄芪甲苷VII,Astrasieversianin VII

Target: Others

Cat.No: T2807

Target: Lipoxygenase, Endogenous Metabolite, TRP/TRPV Channel

Riboflavin Tetrabutyrate

Cat.No: T16747

Target: Reactive Oxygen Species

3-O-p-Coumaroylquinic acid

Cat.No: TN7048

Target: Others

Cat.No: TMS0719

Synonym: 5-O-Methyl-Myo-Inositol,红杉醇,红杉醇,西曲依醇

Target: Others

Cat.No: TN1419

Synonym: beta-Rhamnocitrin,鼠李素

Target: Others, Phospholipase

Cat.No: T1310

Synonym: Thiouracil,硫代由雪,Deracil,2-硫脲嘧啶

Target: Thyroid hormone receptor(THR), NO Synthase

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00295	PAG-2 Protein, Bovine, Recombinant (His) PAG2,Pregnancy-associated glycoprotein 2	Bovine	E. coli
	PAG2 or a processed derivative of this molecule might represent a factor that binds the LH receptor. PAG-2 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 43.6 kDa and the accession number is Q28057.
TMPH-02461	pylS Protein, Methanosarcina barkeri, Recombinant (His) pylS,Pyrrolysine--tRNA ligase,Pyrrolysine--tRNA(Pyl) ligase,...	Methanosarcina barkeri	E. coli
	Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. pylS Protein, Methanosarcina barkeri, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.8 kDa and the accession number is Q46E77.
TMPH-02564	CARNMT1 Protein, Mouse, Recombinant (His & SUMO) Carnosine N-methyltransferase,Carnmt1	Mouse	E. coli
	N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
TMPH-01525	CMAHP Protein, Human, Recombinant (His & Myc) CMAHP,Inactive cytidine monophosphate-N-acetylneuraminic aci...	Human	E. coli
	Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. That protein has no CMP-N-acetylneuraminate monooxygenase activity and is not able to convert CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells in vertebrates. However, it may play a role in Wnt signaling.
TMPY-00585	Annexin A8 Protein, Human, Recombinant (His) ANX8,annexin A8	Human	E. coli
	We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA8 mRNA is expressed in low-proliferative isolated pubertal mouse mammary ductal epithelium and after enforced involution, but not in isolated highly proliferative terminal end buds (TEB) or during pregnancy. ANXA8 as a potential mediator of quiescence in the normal mouse mammary ...

重组蛋白

PAG-2 Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00295

Species: Bovine

Expression System: E. coli

pylS Protein, Methanosarcina barkeri, Recombinant (His)

Cat.No: TMPH-02461

Species: Methanosarcina barkeri

Expression System: E. coli

CARNMT1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02564

Species: Mouse

Expression System: E. coli

CMAHP Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01525

Species: Human

Expression System: E. coli

Annexin A8 Protein, Human, Recombinant (His)

Cat.No: TMPY-00585

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0155	Prasugrel Metabolite Derivative-13C-d3 Mixture of Diastereomers-13C-d3
	Prasugrel Metabolite Derivative-13C-d3 是 Prasugrel Metabolite Derivative 的 13C 和氘代化合物。
TMIH-0156	cis-Clopidogrel-MP-13C-d3 Derivative
	cis-Clopidogrel-MP-13C-d3 Derivative 是 cis-Clopidogrel-MP Derivative 的 13C 和氘代化合物。
T27097	CTP518 CTP 518,Deuterated Atazanivir-D3-1,CTP-518
	CTP518, a deuterated Atazanivir derivative, is a HIV protease inhibitor.
T27982	MBRI-001 MBRI 001,MBRI001. BPI-2358-d,plinabulin-d,NPI-2358-d
	MBRI-001 is a deuterium-substituted plinabulin derivative and a potent anti-cancer agent with better pharmacokinetic characteristics tand lower toxicity.
T19297	Doxazosin D8 UK 33274 D8	Others	Others
	Doxazosin D8 (UK 33274 D8) is a deuterium labeled Doxazosin (UK 33274).Doxazosin, a quinazoline derivative, selectively antagonizes postsynaptic AP1 adrenergic receptor.
TMIH-0454	Prochlorperazine-d8
	Prochlorperazine-d8 是 Prochlorperazine 的氘代化合物。Prochlorperazine 的 CAS 号为 58-38-8。Prochlorperazine 是一种抗精神病药phenothiazine衍生物。
TMIH-0424	Pentoxyfylline-d6
	Pentoxyfylline-d6 是 Pentoxyfylline 的氘代化合物。Pentoxyfylline 的 CAS 号为。Questiomycin A derivatives 20 是一种Questiomycin A衍生物。
TMID-0110	18-Hydroxycorticosterone-d4
	18-Hydroxycorticosterone-d4 是 18-Hydroxycorticosterone 的氘代化合物。18-Hydroxycorticosterone 的 CAS 号为 561-65-9。
TMID-0123	Rifapentine-d9
	Rifapentine-d9 是 Rifapentine 的氘代化合物。Rifapentine 的 CAS 号为 61379-65-5。Rifapentine是可用于肺结核的抗生素。
TMIJ-0484	Thiabendazole NH-d6
	Thiabendazole NH-d6 是 Thiabendazole NH 的氘代化合物。Thiabendazole NH 的 CAS 号为 148-79-8。Thiabendazole 是具有驱虫特性的苯并咪唑衍生物。
TMIJ-0387	Toluene-d8
	Toluene-d8 是 Toluene 的氘代化合物。Toluene 的 CAS 号为 108-88-3。
T37928	13C6 Glucosylsphingosine (d18:1)
	13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS. 1-β-D-Glucosylsphingosine is a lysolipid derivative of glucosylcerebroside that decreases activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner.
TMID-0146	Methylprednisolone-d7
	Methylprednisolone-d7 是 Methylprednisolone 的氘代化合物。Methylprednisolone 的 CAS 号为 83-43-2。Methylprednisolone 是一种具有类似抗炎作用的强的松龙衍生物。它是皮质类固醇，可作用于糖皮质激素受体。它通过激活ACE2并降低 IL-6 水平来改善严重的COVID-19。
TMIH-0120	Bisdesmethoxy Curcumin-d8
	Bisdesmethoxy Curcumin-d8 是 Bisdesmethoxy Curcumin 的氘代化合物。Bisdesmethoxy Curcumin 的 CAS 号为 33171-05-0。Bisdemethoxycurcumin是姜黄素的天然去甲氧基衍生物，具有抗炎和抗癌活性。
TMID-0145	Methylprednisolone-d2
	Methylprednisolone-d2 是 Methylprednisolone 的氘代化合物。Methylprednisolone 的 CAS 号为 83-43-2。Methylprednisolone 是一种具有类似抗炎作用的强的松龙衍生物。它是皮质类固醇，可作用于糖皮质激素受体。它通过激活ACE2并降低 IL-6 水平来改善严重的COVID-19。
TMIH-0587	Trilostane-d3
	Trilostane-d3 是 Trilostane 的氘代化合物。Trilostane 的 CAS 号为 13647-35-3。Trilostane 是一种3 β-羟化类固醇脱氢酶抑制剂，能够作用于库兴氏综合征。
TMIJ-0183	Terazosin-d8
	Terazosin-d8 是 Terazosin 的氘代化合物。Terazosin 的 CAS 号为 63590-64-7。
TMIJ-0097	Sulfasalazine-d4
	Sulfasalazine-d4 是 Sulfasalazine 的氘代化合物。Sulfasalazine 的 CAS 号为 599-79-1。Sulfasalazine 是一种合成的水杨酸衍生物，对含有弹性蛋白的结缔组织具有亲和力，并配制成前药。
TMIJ-0131	rac-Valsartan-d9
	rac-Valsartan-d9 是 rac-Valsartan 的氘代化合物。rac-Valsartan 的 CAS 号为 137862-53-4。Valsarta 是一种血管紧张素 II 受体拮抗剂，有用于高血压和心力衰竭的研究潜力。
T71326	1,3,7-Trimethyluric Acid-d9
	1,3,7-Trimethyluric acid-d9 is intended for use as an internal standard for the quantification of 1,3,7-trimethyluric acid by GC- or LC-MS. 1,3,7-Trimethyluric acid is a derivative of uric acid and a metabolite of caffeine. It is formed from caffeine by the cytochrome P450 isoform CYP3A4. 1,3,7-Trimethyluric acid scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes.
TMIH-0001	(+/-)-Venlafaxine-d6 HCl
	(+/-)-Venlafaxine-d6 HCl 是 (+/-)-Venlafaxine HCl 的氘代化合物。(+/-)-Venlafaxine HCl 的 CAS 号为 99300-78-4。Venlafaxine hydrochloride 是一种口服有效的 5-羟色胺 (5-HT)/去甲肾上腺素 (NE) 重摄取的双重抑制剂，具有抗抑郁活性。
TMID-0249	Terbinafine-d3 hydrochloride
	Terbinafine-d3 hydrochloride 是 Terbinafine hydrochloride 的氘代化合物。Terbinafine hydrochloride 的 CAS 号为 78628-80-5。Terbinafine hydrochloride 具有抗真菌感染活性。它是念珠菌属的角鲨烯环氧化酶的非竞争性抑制剂，Ki值为 30 nM。它还对某些革兰氏阳性和革兰氏阴性细菌具有抗菌活性。
TMID-0135	Melengestrol acetate-d3
	Melengestrol acetate-d3 是 Melengestrol acetate 的氘代化合物。Melengestrol acetate 的 CAS 号为 2919-66-6。Melengestrol acetate 是孕酮的衍生物，充当皮质类固醇激素。 Melengestrol acetate 可以促进月经活动和妊娠维持的子宫内膜增殖延迟。
TMIJ-0310	Pyrazinamide-d3
	Pyrazinamide-d3 是 Pyrazinamide 的氘代化合物。Pyrazinamide 的 CAS 号为 98-96-4。Pyrazinamide是一种口服抗结核类抗生素。它是一种前药，通过结核分枝杆菌pncA基因编码的 PZase/烟酰胺酶转化为活性吡嗪酸形式。
TMIJ-0361	Dimethyl Fumarate-2,3-d2
	Dimethyl Fumarate-2,3-d2 是 Dimethyl Fumarate 的氘代化合物。Dimethyl Fumarate 的 CAS 号为 624-49-7。Dimethyl fumarate 是具有口服活性且可透过血脑屏障的Nrf2激活剂，可诱导抗氧化剂基因表达上调。它是一种富马酸盐衍生物，可作抗炎和免疫调节剂，可研究多发性硬化症。
T12135	Mycophenolic acid-d3 Mycophenolate-d3,Mycophenolate D3	Others; Antibacterial	Microbiology/Virology; Others
	Mycophenolic acid-d3 (Mycophenolate-d3) 是 Mycophenolic acid 的衍生物。Mycophenolic acid 是一种降低GTP 水平和损害RNA 聚合酶II (RNAP II)转录延伸的化合物，促进了近端位点的使用，能够逆转虫草素对选择性聚腺苷化的作用。
TMIJ-0004	Perphenazine-d4
	Perphenazine-d4 是 Perphenazine 的氘代化合物。Perphenazine 的 CAS 号为 58-39-9。Perphenazine 是吩噻嗪衍生物和多巴胺拮抗剂，具有止吐和抗精神病特性。它能够抑制5-HT2A受体，α1A肾上腺素能受体，多巴胺D2、D3、D2L受体，以及组胺H1受体，对应的Ki值分别为5.6、10、0.765、0.13、3.4 和 8 nM。
TMIJ-0239	Cobicistat-d8
	Cobicistat-d8 是 Cobicistat 的氘代化合物。Cobicistat 的 CAS 号为 1004316-88-4。Cobicistat 是一种细胞色素酶P450 3A 的选择性抑制剂，IC50值为30-285 nM。它是一种药代动力学增强剂，可增强抗 HIV 药物的吸收。
TMIJ-0251	Nicergoline-13C-d3
	Nicergoline-13C-d3 是 Nicergoline 的 13C 和氘代化合物。Nicergoline 的 CAS 号为 27848-84-6。Nicergoline 是一种有效的，选择性的、具有口服活性的α1A-肾上腺素能受体拮抗剂，是一种溴烟碱酸的麦角林衍生物。它具有血管舒张作用，可以改善阿尔茨海默症小鼠的认知功能。
T70808	Cabazitaxel-d6
	Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance...
TMIJ-0215	Doxofylline-d4
	Doxofylline-d4 是 Doxofylline 的氘代化合物。Doxofylline 的 CAS 号为 69975-86-6。Doxofylline 是腺苷 A1 受体拮抗剂，且能抑制磷酸二酯酶 IV，用于治疗哮喘。
TMID-0118	Doxofylline-d6
	Doxofylline-d6 是 Doxofylline 的氘代化合物。Doxofylline 的 CAS 号为 69975-86-6。Doxofylline 是腺苷 A1 受体拮抗剂，且能抑制磷酸二酯酶 IV，用于治疗哮喘。
TMIJ-0026	2-NP-AMOZ-d5
	2-NP-AMOZ-d5 是 2-NP-AMOZ 的氘代化合物。2-NP-AMOZ 的 CAS 号为 183193-59-1。2-NP-AMOZ 是 AMOZ 的 2-硝基苯基衍生物，AMOZ 是抗生素呋喃他酮的代谢产物。2-NP-AMOZ 专门作为蛋白质结合 AMOZ 检测的可靠工具。
TMIJ-0328	Mometasone furoate-d3
	Mometasone furoate-d3 是 Mometasone furoate 的氘代化合物。Mometasone furoate 的 CAS 号为 83919-23-7。Mometasone furoate 是糖皮质激素受体激动剂，具有抗炎和抗过敏作用。它是皮质固醇类试剂，动物模型中，可局部应用于气道炎症、慢性皮肤湿疹、哮喘。
TMID-0065	Adenine-2-d1
	Adenine-2-d1 是 Adenine 的氘代化合物。Adenine 的 CAS 号为 73-24-5。Adenine 是一种嘌呤衍生物，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
T37608	Riluzole-13C,15N2 Riluzole-13C,15N2
	Riluzole-13C,15N2 is intended for use as an internal standard for the quantification of riluzole by GC- or LC-MS. Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals a...
TMIH-0205	Duloxetine-d3 HCl
	Duloxetine-d3 HCl 是 Duloxetine HCl 的氘代化合物。Duloxetine HCl 的 CAS 号为 136434-34-9。Duloxetine hydrochloride 是一种 5-羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂 (SNRI)，Ki=4.6 nM，可用于广泛性焦虑症的研究。
TMIJ-0024	2-NP-AOZ-d4
	2-NP-AOZ-d4 是 2-NP-AOZ 的氘代化合物。2-NP-AOZ 的 CAS 号为 19687-73-1。2-NP-AOZ 是 AOZ 的 2-硝基苯基衍生物的一种化合物，AOZ 是呋喃唑酮的组织结合代谢产物。2-NP-AOZ 专门用于 AOZ 残留物的测定。
TMID-0250	2-hydroxy-4-methoxybenzophenone-d5
	2-hydroxy-4-methoxybenzophenone-d5 是 2-hydroxy-4-methoxybenzophenone 的氘代化合物。2-hydroxy-4-methoxybenzophenone 的 CAS 号为 131-57-7。Oxybenzone 是晒黑和皮肤保护剂中常用的紫外线过滤剂。它是二苯甲酮的衍生物，用作破坏内分泌的化学物质，可穿透胎盘和血脑屏障。它损害自噬，改变表观遗传状态并破坏凋亡神经元细胞中的类维生素 X 受体信号传导。
TMID-0076	Busulfan-d8
	Busulfan-d8 是 Busulfan 的氘代化合物。Busulfan 的 CAS 号为 55-98-1。Busulfan 是二甲磺酸盐的合成衍生物，具有抗肿瘤和细胞毒特性。是一种烷化剂，对骨髓具有选择性免疫抑制作用。
TMIJ-0274	Sulindac-d3
	Sulindac-d3 是 Sulindac 的氘代化合物。Sulindac 的 CAS 号为 38194-50-2。Sulindac 是一种非甾体类抗炎剂，可抑制COX-2的活性，也可抑制 COX-2 的过表达。它是一种亚磺酰基茚衍生物前药，具有潜在的抗肿瘤活性。
TMIJ-0090	L-Carnitine-d9
	L-Carnitine-d9 是 L-Carnitine 的氘代化合物。L-Carnitine 的 CAS 号为 541-15-1。L-carnitine 是一种人内源性分子，在人体内以蛋氨酸和赖氨酸为底物进行生物合成，并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。
TMID-0072	Imipenem-d4
	Imipenem-d4 是 Imipenem 的氘代化合物。Imipenem 的 CAS 号为 64221-86-9。Imipenem (MK0787) 是一种噻吩霉素衍生物，属于抗生素类，具有抗菌活性，对革兰氏阳性和革兰氏阴性菌具有部分的抑制作用。Imipenem 可用于研究碳青霉烯类非易感性感染和铜绿假单胞菌生物膜感染。
TMIJ-0127	Diclofenac-d4
	Diclofenac-d4 是 Diclofenac 的氘代化合物。Diclofenac 的 CAS 号为 15307-86-5。Diclofenac 是一种具有抗炎活性的非甾体苯乙酸衍生物，是COX抑制剂，在 CHO 细胞中，对人 COX-1 和 COX-2 的IC50值分别为 4 和 1.3 nM。它对绵羊 COX-1 和 COX-2 的IC50值分别为 5.1 μM，0.84 μM。它通过活化 caspase 级联反应来诱导神经干细胞凋亡。
TMIJ-0314	Baclofen-d4
	Baclofen-d4 是 Baclofen 的氘代化合物。Baclofen 的 CAS 号为 1134-47-0。Baclofen 是 γ-氨基丁酸 (GABA) 的亲脂性衍生物，是可口服的选择性代谢型 GABA-B 受体激动剂，具有高血脑屏障渗透率，用于治疗因脊髓损伤和多发性硬化引起的痉挛。
T36408	Rhein-13C4 Rhein-13C4
	Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerein . At 10 μM, rhein inhibits IL-1β signaling, suppressing signaling through NF-κB, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13.1 It inhibits IKKβ (IC50 = 11.8 μM), decreasing iNOS and IL-6 expression in LPS-stimulated macrophages but paradoxically i...
TMIH-0314	Lurasidone-d8 HCl
	Lurasidone-d8 HCl 是 Lurasidone HCl 的氘代化合物。Lurasidone HCl 的 CAS 号为 367514-88-3。Lurasidone hydrochloride 是多巴胺 D2和5-HT7的拮抗剂，IC50值分别为 1.68 和 0.495 nM，用于治疗精神分裂症和双相情感障碍。它也是5-HT1A受体的部分激动剂，IC50值为 6.75 nM。
TMIJ-0205	Glycyrrhetinic acid-d3
	Glycyrrhetinic acid-d3 是 Glycyrrhetinic acid 的氘代化合物。Glycyrrhetinic acid 的 CAS 号为 1449-05-4。Glycyrrhetinic acid是一种饮食衍生的化合物，是NF-kB的抑制剂和蛋白酶体的激活剂，在多细胞生物中起到促进长寿和抗聚集因子的作用。它诱导细胞凋亡。
TMID-0119	Diprophylline-d6
	Diprophylline-d6 是 Diprophylline 的氘代化合物。Diprophylline 的 CAS 号为 479-18-5。Diphylline 是一种A1/A2腺苷受体拮抗剂，也是环状核苷酸磷酸二酯酶抑制剂。它是一种黄嘌呤衍生物，具有支气管扩张和血管扩张作用，有用于治疗慢性支气管炎和肺气肿的潜力。
T71328	Theobromine-d6
	Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It is an adenosine A1 receptor antagonist. Theobromine increases AMPK phosphorylation and inhibits adipocyte differentiation, ERK and JNK phosphorylation, and IL-6 and TNF-α production in 3T3-L1 preadipocytes cultured in differentiation medium....
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同位素标记化合物

Prasugrel Metabolite Derivative-13C-d3

Cat.No: TMIH-0155

Synonym: Mixture of Diastereomers-13C-d3

cis-Clopidogrel-MP-13C-d3 Derivative

Cat.No: TMIH-0156

Cat.No: T27097

Synonym: CTP 518,Deuterated Atazanivir-D3-1,CTP-518

Cat.No: T27982

Synonym: MBRI 001,MBRI001. BPI-2358-d,plinabulin-d,NPI-2358-d

Cat.No: T19297

Synonym: UK 33274 D8

Target: Others

Prochlorperazine-d8

Cat.No: TMIH-0454

Pentoxyfylline-d6

Cat.No: TMIH-0424

18-Hydroxycorticosterone-d4

Cat.No: TMID-0110

Cat.No: TMID-0123

Thiabendazole NH-d6

Cat.No: TMIJ-0484

Cat.No: TMIJ-0387

13C6 Glucosylsphingosine (d18:1)

Cat.No: T37928

Methylprednisolone-d7

Cat.No: TMID-0146

Bisdesmethoxy Curcumin-d8

Cat.No: TMIH-0120

Methylprednisolone-d2

Cat.No: TMID-0145

Cat.No: TMIH-0587

Cat.No: TMIJ-0183

Sulfasalazine-d4

Cat.No: TMIJ-0097

rac-Valsartan-d9

Cat.No: TMIJ-0131

1,3,7-Trimethyluric Acid-d9

Cat.No: T71326

(+/-)-Venlafaxine-d6 HCl

Cat.No: TMIH-0001

Terbinafine-d3 hydrochloride

Cat.No: TMID-0249

Melengestrol acetate-d3

Cat.No: TMID-0135

Pyrazinamide-d3

Cat.No: TMIJ-0310

Dimethyl Fumarate-2,3-d2

Cat.No: TMIJ-0361

Mycophenolic acid-d3

Cat.No: T12135

Synonym: Mycophenolate-d3,Mycophenolate D3

Target: Others, Antibacterial

Perphenazine-d4

Cat.No: TMIJ-0004

Cat.No: TMIJ-0239

Nicergoline-13C-d3

Cat.No: TMIJ-0251

Cat.No: T70808

Cat.No: TMIJ-0215

Cat.No: TMID-0118

Cat.No: TMIJ-0026

Mometasone furoate-d3

Cat.No: TMIJ-0328

Cat.No: TMID-0065

Riluzole-13C,15N2

Cat.No: T37608

Synonym: Riluzole-13C,15N2

Duloxetine-d3 HCl

Cat.No: TMIH-0205

Cat.No: TMIJ-0024

2-hydroxy-4-methoxybenzophenone-d5

Cat.No: TMID-0250

Cat.No: TMID-0076

Cat.No: TMIJ-0274

Cat.No: TMIJ-0090

Cat.No: TMID-0072

Cat.No: TMIJ-0127

Cat.No: TMIJ-0314

Cat.No: T36408

Synonym: Rhein-13C4

Lurasidone-d8 HCl

Cat.No: TMIH-0314

Glycyrrhetinic acid-d3

Cat.No: TMIJ-0205

Diprophylline-d6

Cat.No: TMID-0119

Cat.No: T71328

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