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Search Results for " deoxycholic acid "

Targets Recommended: Others

抑制剂 & 化合物

天然产物

重组蛋白

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T84944	3-Epideoxycholic Acid EDCA	Others	Others
	3-Epideoxycholic acid (EDCA), a secondary bile acid and an epimer of deoxycholic acid, serves as a steroidal host compound in the enantioselective purification of (2R,3S)-3-methyl-2-pentanol from its racemates via enclathration. Additionally, decreased fecal levels of EDCA have been observed in pediatric patients with non-alcoholic fatty liver disease (NAFLD).

化合物

3-Epideoxycholic Acid

Cat.No: T84944

Synonym: EDCA

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2965	Deoxycholic acid Cholorebic,去氧胆酸,脱氧胆酸,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic	Endogenous Metabolite; GPCR19	GPCR/G Protein; Metabolism
	Deoxycholic acid (Cholanoic Acid) 是 G 蛋白偶联胆汁酸受体 TGR5的激活剂。
TN7120	7-keto-deoxycholic acid 7-Keto-3alpha,12alpha-dihydroxycholanic acid	Others	Others
	7-keto-deoxycholic acid 是由乳酸杆菌和双歧杆菌在特定条件下和体外胆酸转化而来的。
T5077	Deoxycholic acid sodium salt 脱氧胆酸钠,Sodium deoxycholate,Sodium Desoxycholate	Endogenous Metabolite; GPCR19	GPCR/G Protein; Metabolism
	Deoxycholic acid sodium salt (Sodium deoxycholate) 是 G 蛋白偶联胆汁酸受体TGR5的激活剂。
T8207	Evolitrine	Others	Others
	Evolitrine 是一种来源于Acronychia pedunculata、具有抗炎作用的物质。
T5259	Glycochenodeoxycholic acid sodium salt GCDCA,甘氨鹅脱氧胆酸钠,Sodium glycochenodeoxycholate	Apoptosis; Others; Endogenous Metabolite	Apoptosis; Metabolism; Others
	Glycochenodeoxycholic acid sodium salt 是一种从脱氧鹅胆酸和甘氨酸在肝脏中形成的胆汁盐，可诱导肝细胞凋亡。它起到洗涤剂的作用，可溶解脂肪吸收，并本身被吸收。
TWA2417	Sodium taurocholate 牛黄胆酸钠(牛胆酸钠，牛胆酸钠盐，牛磺膽酸鈉，牛磺胆酸钠，牛磺胆酸钠盐，牛胆酸钠水合物，水合牛磺胆酸钠，牛胆酸钠(混合物)，牛黄胆酸钠(水合)，牛磺胆酸钠(标准品)),Taurocholate Sodium	Others	Others
	Sodium taurocholate (Taurocholate Sodium) hydrate 具有显著的生物学效应，例如通过上调 VEGF-A 的表达抑制肝动脉结扎所致的胆道损伤。对免疫系统具有一定的调节作用。
T75319	Taurodeoxycholic acid Taurodeoxychloic acid	Apoptosis; Calcium Channel; Caspase	Apoptosis; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome
	Taurodeoxycholic acid (Taurodeoxychloic acid) 是脱氧胆酸的胆汁酸牛磺酸共轭物，是一种人体代谢物，可稳定线粒体膜，减少自由基形成。Taurodeoxycholic acid 通过阻断钙介导的凋亡通路以及 Caspase-12 激活来抑制凋亡 (apoptosis)。Taurodeoxycholic acid具有神经保护活性，可用于研究 3-硝基丙酸诱导或稳定遗传的亨廷顿舞蹈病 (HD) 。
T36585	Isodeoxycholic Acid isoDCA	Chloride channel; Antibacterial	Membrane transporter/Ion channel; Microbiology/Virology
	Isodeoxycholic Acid 是一种胆汁酸，由肠道细菌通过脱氧胆酸的表聚作用形成。Isodeoxycholic acid 的临界胶束浓度高于二氯苯甲醚，这表明它的去污活性降低了，而且在抑制七种肠道共生细菌生长方面的活性低于二氯苯甲醚。Isodeoxycholic Acid（0.1%）能抑制几种艰难梭菌菌株在牛磺胆酸诱导下的孢子萌发，并能降低艰难梭菌培养上清对 Vero 细胞的细胞毒性。在高脂饮食诱发肥胖的大鼠模型中，血浆中的Isodeoxycholic acid 水平比正常饮食的大鼠低。

天然产物

Deoxycholic acid

Cat.No: T2965

Synonym: Cholorebic,去氧胆酸,脱氧胆酸,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic

Target: Endogenous Metabolite, GPCR19

7-keto-deoxycholic acid

Cat.No: TN7120

Synonym: 7-Keto-3alpha,12alpha-dihydroxycholanic acid

Target: Others

Deoxycholic acid sodium salt

Cat.No: T5077

Synonym: 脱氧胆酸钠,Sodium deoxycholate,Sodium Desoxycholate

Target: Endogenous Metabolite, GPCR19

Glycochenodeoxycholic acid sodium salt

Cat.No: T5259

Synonym: GCDCA,甘氨鹅脱氧胆酸钠,Sodium glycochenodeoxycholate

Target: Apoptosis, Others, Endogenous Metabolite

Sodium taurocholate

Cat.No: TWA2417

Synonym: 牛黄胆酸钠(牛胆酸钠，牛胆酸钠盐，牛磺膽酸鈉，牛磺胆酸钠，牛磺胆酸钠盐，牛胆酸钠水合物，水合牛磺胆酸钠，牛胆酸钠(混合物)，牛黄胆酸钠(水合)，牛磺胆酸钠(标准品)),Taurocholate Sodium

Target: Others

Taurodeoxycholic acid

Cat.No: T75319

Synonym: Taurodeoxychloic acid

Target: Apoptosis, Calcium Channel, Caspase

Isodeoxycholic Acid

Cat.No: T36585

Synonym: isoDCA

Target: Chloride channel, Antibacterial

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01372	Cornulin Protein, Human, Recombinant (His) Tumor-Related Protein,58 kDa Heat Shock Protein,PDRC1,C1orf1...	Human	E. coli
	Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and ...

重组蛋白

Cornulin Protein, Human, Recombinant (His)

Cat.No: TMPJ-01372

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0182	Deoxycholic-2,2,4,4-d4 Acid
	Deoxycholic-2,2,4,4-d4 Acid 是 Deoxycholic-2,2,4,4 Acid 的氘代化合物。
TMID-0052	Taurocholic Acid-d4 Sodium
	Taurocholic Acid-d4 Sodium 是 Taurocholic Acid Sodium 的氘代化合物。Taurocholic Acid Sodium 的 CAS 号为 145-42-6。Sodium taurocholate hydrate 具有显著的生物学效应，例如通过上调 VEGF-A 的表达抑制肝动脉结扎所致的胆道损伤。对免疫系统具有一定的调节作用。