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Search Results for " dsp6952 "
Targets Recommended: Others

2

抑制剂 & 化合物

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T71308 DSP-6952

Others Others
DSP-6952 is a 5-HT4 receptor partial agonist, inhibiting visceral hypersensitivity and ameliorating gastrointestinal dysfunction.
T1415 Gemfibrozil

吉非罗齐,CI-719,Jezil,Decrelip,Lopid

P450; Adrenergic Receptor; PPAR DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
Gemfibrozil (CI-719) 是一种PPAR-α激活剂,可作为降脂药。它也是P450非选择性抑制剂,对 CYP2C9、2C19、2C8 和 1A2 的Ki 值分别为 5.8、24、69 和 82 μM。

化合物

DSP-6952
Cat.No: T71308
Synonym:
Target: Others
Gemfibrozil
Cat.No: T1415
Synonym: 吉非罗齐,CI-719,Jezil,Decrelip,Lopid
Target: P450, Adrenergic Receptor, PPAR
Cat. No. Product Name Target Signaling Pathways
T71306 Gemfibrozil-d6

Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif l...

同位素标记化合物

Gemfibrozil-d6
Cat.No: T71306
Synonym:
Target:
TargetMol Loading
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