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Search Results for " dpd "

Targets Recommended: HIF

10

抑制剂 & 化合物

1

天然产物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T7692	2,4-DPD	HIF	Angiogenesis; Chromatin/Epigenetic
	2,4-DPD 是氧感应酶 HIF-α 脯氨酰羟化酶 (HIF-PH) 的竞争性抑制剂。
T31571	DPD 20027 DPD20027,DPD-20027,Lanray L	Others	Others
	DPD 20027 is a bioactive chemical.
TP2036L	DPDPE TFA (88373-73-3 free base) DPDPE TFA	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	DPDPE TFA 是选择性 δ-阿片受体激动剂肽，在体内具有镇痛作用。
T28007	MDPD	Others	Others
	MDPD is an enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis. MDPD alleviates the growth inhibitory effects of NAE 12:0, in part by enhancing the enzymatic activity of Arabidopsis FAAH (AtFAAH).
TP2036	DPDPE	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	DPDPE 是选择性 δ-阿片受体激动剂肽，在体内具有镇痛作用。
T7614	Eniluracil GW776C85,5-Ethynyluracil	Others	Others
	Eniluracil (GW776C85) 是不可逆的二氢嘧啶脱氢酶(DPD)抑制剂，是一种尿嘧啶类似物，能够使 5-FU 的口服生物利用度提高到 100%，促进均匀吸收和可预测的毒性。
T13089	TAS-114 TAS114,TAS 114	Others	Others
	TAS-114 是一种具有口服活性的 dUTPase 和二氢嘧啶脱氢酶 (DPD) 的双重抑制剂。 TAS-114 靶向5-FU的细胞间代谢以增强抗肿瘤活性，调节分解代谢途径以改善5-FU的全身可用性。
T38294	4-Deoxypyridoxine hydrochloride	S1P Receptor	GPCR/G Protein
	4-Deoxypyridoxine hydrochloride 通过抑制 S1P 裂解酶 (SPL) 活性来抑制细胞内 S1P 的降解，与 S1P 一样，减少化学诱导的胰岛素瘤细胞系的细胞凋亡。
T0987	Gimeracil 吉美嘧啶,吉莫斯特,Gimestat	Autophagy	Autophagy
	Gimeracil (Gimestat) 是一种竞争性可逆的 DPYD(二氢嘧啶脱氢酶，DPD) 有效抑制剂，是口服氟嘧啶衍生物 S-1 的成分，能够抑制 DNA DSB 的修复。
T35439	(E)-5-(2-Bromovinyl)uracil	Others	Others
	(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner. It enhances the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil in a P388 murine leukemia model when administered at a dose of 200 μmol/kg, increasing survival time.

化合物

Cat.No: T7692

Target: HIF

Cat.No: T31571

Synonym: DPD20027,DPD-20027,Lanray L

Target: Others

DPDPE TFA (88373-73-3 free base)

Cat.No: TP2036L

Synonym: DPDPE TFA

Target: Opioid Receptor

Cat.No: T28007

Target: Others

Cat.No: TP2036

Target: Opioid Receptor

Cat.No: T7614

Synonym: GW776C85,5-Ethynyluracil

Target: Others

Cat.No: T13089

Synonym: TAS114,TAS 114

Target: Others

4-Deoxypyridoxine hydrochloride

Cat.No: T38294

Target: S1P Receptor

Cat.No: T0987

Synonym: 吉美嘧啶,吉莫斯特,Gimestat

Target: Autophagy

(E)-5-(2-Bromovinyl)uracil

Cat.No: T35439

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T4886	Dihydrouracil 二氢尿嘧啶,5,6-Dihydrouracil	Endogenous Metabolite	Metabolism
	Dihydrouracil (5,6-Dihydrouracil) 是一种尿嘧啶的代谢产物，能够作为鉴定二氢嘧啶脱氢酶 (DPD) 缺陷的标志物。

天然产物

Cat.No: T4886

Synonym: 二氢尿嘧啶,5,6-Dihydrouracil

Target: Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01133	Latent TGF beta 1 Protein, Human, Recombinant (His) CED,DPD1,transforming growth factor, beta 1,TGF β1,...	Human	HEK293 Cells
	Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPY-05521	Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated TGFB,TGF β1,转化生长因子,TGF-beta 1,transforming growth factor, be...	Human	HEK293 Cells
	Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPJ-00250	LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated transforming growth factor β1,TGFβ,CED,TGFB,TGFbeta,LAP (TGF...	Human	HEK293 Cells
	Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activation of these complexes is a critical step in regulation of TGFβ function in vivo. The TGFβ1 LAP is a ligand for the integrin αvβ6 and that αvβ6-expressing cells induce spatially restricted activition of TGFβ1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with ...
TMPH-00735	LuxS Protein, E. coli, Recombinant (His & Myc) luxS,S-ribosylhomocysteine lyase,Autoinducer-2 production pr...	E. coli	E. coli
	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
TMPH-00734	LuxS Protein, E. coli, Recombinant (His) AI-2 synthesis protein,Autoinducer-2 production protein LuxS...	E. coli	E. coli
	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). LuxS Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. Th...

重组蛋白

Latent TGF beta 1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01133

Species: Human

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05521

Species: Human

Expression System: HEK293 Cells

LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00250

Species: Human

Expression System: HEK293 Cells

LuxS Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00735

Species: E. coli

Expression System: E. coli

LuxS Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00734

Species: E. coli

Expression System: E. coli

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