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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19080 |
DOPE
1,2-二油酰-SN-甘油-3-磷酰乙醇胺 |
Others | Others |
DOPE (DOPE) 是一种阳离子脂质体的中性辅助脂质 (helper lipid),能够与阳离子磷脂结合,增强裸 siRNA 的转染效率。 | |||
T74882 |
DOPE-GA
|
Others | Others |
DOPE-GA 可用于制备脂质体,用于药物递送的研究。 | |||
T74883 |
DOPE-NHS
|
Others | Others |
DOPE-NHS是一种连接子,用于多肽与外泌体或其他可能的基于膜的纳米颗粒的结合,适用于药物递送。 | |||
T77276 |
DOPE-mPEG (MW 2000)
|
Others | Others |
DOPE-mPEG (MW 2000),一种磷脂多分散PEG(亦称DOPE脂质体),广泛应用于制备靶向给药脂质体及巨大单层囊泡(GUVs)。此化合物能显著降低脂质体对pH的敏感性,其作用具浓度依赖性。 | |||
T35606 |
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium
1,2-Dioleoyl-sn-glycero-3-PS (sodium salt) |
Others | Others |
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)) 可与 DOPC 和 DOPE 一起用于脂质混合物中,作为有效的无毒和非病毒 DNA 载体。 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium 已用于单层囊泡的形成,以研究曲率对膜结构的影响,并用于支持脂质双层的形成,以研究各种支持膜小叶之间脂质重新分布的材料。 | |||
T11318 |
Dopexamine hydrochloride
盐酸多培沙明,FPL60278AR |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Dopexamine hydrochloride (FPL60278AR) 是β2肾上腺素能受体激动剂。 | |||
T9409 |
Mesdopetam hemitartrate
IRL790 hemitartrate,1-Propanamine, N-[2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Mesdopetam hemitartrate (IRL790 hemitartrate) 是一种多巴胺D3受体拮抗剂 (Ki=90 nM;IC50=9.8 μM),具有稳定精神运动的作用,可用于帕金森病的运动和精神并发症的研究。 | |||
T4506 |
Gadopentetate dimeglumine
Meglumine gadopentetate,SH-L-451A,Gd-DTPA,Gadopentetic acid dimeglumine,钆喷酸葡胺,Gadopentetic acid dimeglumine salt |
Others | Others |
Gadopentetate dimeglumine 可用于核磁共振成像 (MRI) 中,使血管、器官和其他非骨组织能够更清晰地被看到。Gadopentetate dimeglumine 可诱导生精细胞萎缩。 | |||
T19332 |
Gadopentetic acid
gadolinium complex,钆喷酸,Gd-DTPA |
Others | Others |
Gadopentetic acid (gadolinium complex) 是一种顺磁性造影剂,通常通过静脉内注射 (i.v.) 的方式用于 DCE-MRI 研究。 | |||
T8653 |
DOPEXAMINE
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
DOPEXAMINE 是一种多巴胺能激动剂。 | |||
T12546 |
Prolyl Endopeptidase Inhibitor 1
(Boc)-Prolyl-prolinal,BPP,Boc-Pro-prolinal |
Others | Others |
Prolyl Endopeptidase Inhibitor 1 is a potent inhibitor of prolyl endopeptidase (PEP; PE)(Ki : 15 nM) , has anti-amnesic effect. | |||
T64726 |
tert-Butyl 5-iodopentanoate
|
Others | Others |
tert-Butyl 5-iodopentanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64726,CAS号为 56198-37-9。 | |||
T21094 |
Pseudopelletierine free base
NSC 116056,Granatonine,Pseudopelletierine,Granatan-3-one |
Others | Others |
Pseudopelletierine is the main alkaloid derived from the root-bark of Punica granatum, along with at least three other alkaloids: isopelletierine, methylpelleteirine (C9H17ON) and pelletierine, which yield 1.8, 0.01, 0.20 and 0.52 grams per kilogram of ra | |||
T124545 |
Pseudopelletierine hydrochloride
|
Others | Others |
Pseudopelletierine hydrochloride 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124545。 | |||
T36181 |
Quinaldopeptin
|
Others | Others |
Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 μg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 μg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM). | |||
T29566 |
Acetamide, N-(5-amino-2-((5-phthalimidopentyl)oxy)benzyl)-
|
Others | Others |
Acetamide, N-(5-amino-2-((5-phthalimidopentyl)oxy)benzyl)- is a bioactive chemical. | |||
T30331 |
Benzamide, 5-amino-2-((5-phthalimidopentyl)oxy)-
|
Others | Others |
Benzamide, 5-amino-2-((5-phthalimidopentyl)oxy)- is a bioactive chemical. | |||
T64439 |
tert-Butyl 5-iodopentylcarbamate
|
Others | Others |
tert-Butyl 5-iodopentylcarbamate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64439。 | |||
T38828 |
Mesdopetam
IRL790 |
Others | Others |
Mesdopetam (IRL790) is a dopamine D3 receptor antagonist with a Ki of 90 nM and an IC50 of 9.8 μM for the human recombinant D3 receptor. It exhibits psychomotor stabilizing properties and is utilized in the study of motor and psychiatric complications associated with Parkinson's disease. | |||
T84661 |
cKK-E15
|
Others | Others |
cKK-E15,一种肽-脂质化合物,与C14PEG2000、未修饰的胆固醇以及DOPE共配制成LNP3。 | |||
T37027 |
MHAPC-Chol
|
Others | Others |
MHAPC-Chol is a cationic cholesterol. MHAPC-Chol, as part of a lipoplex with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability. It has also been used to deliver siRNA into mice via intravenous injection, resulting in MHAPC-chol accumulation in the liver. | |||
T37017 |
OH-C-Chol
|
Others | Others |
OH-C-Chol is a cationic cholesterol derivative. OH-C-Chol, as a component of lipoplexes with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells as well as in mice via intravenous injection, resulting in lipoplex accumulation in the liver. | |||
T37586 |
DMHAPC-Chol
|
Others | Others |
DMHAPC-Chol is a cationic cholesterol. Liposomes containing DMHAPC-chol have been used for DNA plasmid delivery in vitro and in vivo in a B16-F10 mouse xenograft model. Liposomes containing DMHAPC-chol are cytotoxic to B16-F10 cells when used at lipid concentrations greater than 20 μM. DMHAPC-Chol, as part of a lipoplex with DOPE , has also been used to deliver DNA into mouse lung via intratracheal injection, resulting in a heterogeneous distribution in the bronchi and bronchioles, and to delive... | |||
T37035 |
HAPC-Chol
|
Others | Others |
HAPC-Chol is a cationic cholesterol. HAPC-Chol, as part of a lipoplex with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability. It has also been used to deliver siRNA into mice via intravenous injection, resulting in HAPC-chol accumulation in the lungs. | |||
T37018 |
OH-Chol
|
Others | Others |
OH-Chol is a cationic cholesterol derivative.1 OH-Chol, as a component of lipoplexes with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells, as well as in mice via intravenous injection, resulting in lipoplex accumulation in the liver. It has also been used in cationic nanoparticles in combination with Tween 80 to transfect pDNA and siRNA into PC3 mouse xenografts via intratumoral injection and with Tween 80 and folate-PEG2000-DSPE in a KB mouse xenograft model for intrat... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2931 |
2-Amino-5-ureidopentanoic acid
DL-Citrulline,Citrulline,瓜氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
2-Amino-5-ureidopentanoic acid (Citrulline) 存在于肝脏中,不是蛋白质的构成成分,为人体脲循环的一个重要中间物,可与鸟氨酸、精氨酸合用治疗高氨血症。 | |||
TN4314 |
Isonardoperoxide
|
Antifection | Microbiology/Virology |
Isonardoperoxide shows strong antimalarial activity against Plasmodium falciparum malaria (6.0 × 10-7 M). | |||
T75623 |
Sadopeptins A
|
Others | Others |
Sadopeptins A 是一种天然产物,可以从 Streptomycessp 中分离出来。Sadopeptins A 是一种有效的蛋白酶体抑制剂。 | |||
T75624 |
Sadopeptins B
|
Others | Others |
Sadopeptins B 是一种天然产物,可以从 Streptomycessp 中分离出来。Sadopeptins B 是一种有效的蛋白酶体抑制剂。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03171 |
Lysyl endopeptidase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
Lysyl endopeptidase,prpL,PvdS-regulated endoproteas... |
Pseudomonas aeruginosa | E. coli |
Lysine-specific endoprotease. Involved in corneal virulence. Lysyl endopeptidase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 42.4 kDa and the accession number is Q9HWK6. | |||
TMPY-03269 |
Prolyl Endopeptidase Protein, Mouse, Recombinant (His)
PEP,AI450383,AI047692,D10Wsu136e,prolyl endopeptida... |
Mouse | Baculovirus Insect Cells |
Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptidase degrades the nonapeptide bradykinin at the Pro-Phe bond. It is involved in the maturation and degradation of peptide hormones and neuropeptides such as alpha-melanocyte-stimulating hormone, luteinizing hormone-releasing hormone (LH-RH), thyrotropin-releasing hormone, angiotens... | |||
TMPH-00582 |
Endopeptidase Clp Protein, E. coli, Recombinant (His & Myc)
clpP,ATP-dependent Clp protease proteolytic subunit,Endo... |
E. coli | E. coli |
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. | |||
TMPH-02415 |
Lysyl endopeptidase Protein, Lysobacter enzymogenes, Recombinant (His & SUMOstar)
Lys-C,Lysyl endopeptidase |
Lysobacter enzymogenes | P. pastoris (Yeast) |
Highly specific endopeptidase that hydrolyzes lysyl bonds including the Lys-Pro bond. Lysyl endopeptidase Protein, Lysobacter enzymogenes, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The predicted molecular weight is 44.0 kDa and the accession number is Q7M135. |