首页工具

登录

搜索结果

Search Results for " dopa "

Targets Recommended: Dopamine Receptor DNA/RNA Synthesis

66

抑制剂 & 化合物

20

天然产物

11

重组蛋白

7

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T26396	6-Hydroxy-DOPA 6-羟基-DL-多巴,6-Hydroxy-DL-DOPA	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	6-Hydroxy-DOPA 是 RAD52 的变构抑制剂，可用于癌症研究。它在体外抑制 BRCA 缺陷癌细胞的增殖，也抑制 APE1。
T31570	DPBX-L-Dopa DPBX L-Dopa	Others	Others
	DPBX-L-Dopa is a boron-containing dopa-derivative, acting as a bladder relaxant through non-catecholamine receptors.
T37605	D-DOPA	Others	Others
	D-DOPA is an enantiomer of the dopamine precursor L-DOPA . It can be converted to L-DOPAviasequential oxidation and transamination, which are mediated by D-amino acid oxidase (DAAO) and DOPA transaminase, respectively, in rat kidney homogenates.1It reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner.2Intraventricular administration of D-DOPA (200 μg/animal) increases striatal dopamine levels in rats.3D-DOPA (20 mg/kg, i.p...
T23275	RuBi-Dopa	Others	Others
	dopamine receptor activator
T24047	Etilevodopa hydrochloride Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester	Others; Dopamine Receptor; Drug Metabolite	GPCR/G Protein; Metabolism; Neuroscience; Others
	Etilevodopa hydrochloride (L-DOPA ethyl ester) 是 Levodopa 的前药，在胃肠道中被非特异性酯酶快速水解产生 Levodopa 和乙醇。Levodopa 是多巴胺的前体，有助于中枢神经系统的渗透和传递多巴胺。Etilevodopa HCl 可用于帕金森病 (PD)的相关研究。
T36122	3-O-methyl-L-DOPA (hydrate)	Others	Others
	3-O-methyl-L-DOPA is a metabolite of L-DOPA , produced by the activity of catechol O-methyltransferase. 3-O-methyl-L-DOPA may have effects of its own or it may compete with the actions of L-DOPA.
T31823	Fluorodopa F 18 Fluorodopa (18F),6-(18F)Fluoro-L-DOPA,F-DOPA,L-6-(18F)Fluoro-DOPA,6-(18F)Fluorodopamine	Others	Others
	Fluorodopa F 18 can be used as radioactive agent.
T20700	Racemetirosine	Others	Others
	Racemetirosine 是一种酪氨酸 3-单加氧酶抑制剂，因此会抑制儿茶酚胺的合成。
T74180	[18F]-Labeled L-dopa precursor	Others	Others
	[18F]-Labeled L-dopa precursor 是用于合成 18F-labeled L-dopa 的前体。
T2148	Carbidopa monohydrate Carbidopa Hydrate,S(-)-Carbidopa,卡比多巴水合物	Decarboxylase; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism; Others
	Carbidopa monohydrate (S(-)-Carbidopa) 是一种外周型脱羧酶抑制剂，可用于帕金森病的研究。它是一种选择性芳香烃受体 (AhR) 调节剂。它抑制胰腺癌细胞和肿瘤生长。
T5954	Methyldopa hydrate L-甲基多巴,Alpha-Methyldopa Sesquihydrate,L-(-)-α-Methyldopa hydrate,MK-351 hydrate,Methyldopa Sesquihydrate	Dopamine Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Methyldopa hydrate (MK-351 hydrate) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是一种 α-肾上腺素能激动剂，对α2-adrenergic receptors 有选择性。
T60075	Dopamine D2 receptor agonist-2 Dopamine D2 Receptor	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) 是靶向多巴胺D2受体的配体。
T12352	Oxidopamine hydrochloride 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride,6-羟基多巴胺盐酸盐	Mitophagy; Dopamine Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) 是一种神经递质多巴胺拮抗剂，可选择性地破坏多巴胺能神经元，是一种广泛使用的神经毒素。
T11077	Dopamine D2 receptor antagonist-1	Others	Others
	Dopamine D2 receptor antagonist-1，一种对多巴胺D2受体（D2R）表现出亚毫摩尔级别亲和力的负变构调节剂（NAM）。
T6835	Fenoldopam mesylate Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Fenoldopam mesylate (Corlopam mesylate) 是一种多巴胺受体D1选择性激动剂。
T13512	5-Hydroxydopamine hydrochloride	Antifungal	Microbiology/Virology
	5-Hydroxydopamine hydrochloride 是人体尿液中的一种天然胺,对卢克斯普受体的 IC50 值为 22 µM 。5-Hydroxydopamine hydrochloride 具有潜在的抗菌活性和抗癌活性。
T62530	N-Arachidonyldopamine NADA	Cannabinoid Receptor	GPCR/G Protein
	N-Arachidonyldopamine (NADA) 是一种选择性的、强效的内源性 CB1 受体激动剂 (Ki: 250 nM)。N-Arachidonyldopamine 也是一种有效的、选择性 TRPV1 激动剂，其 EC50 值 ~50 nM。
T2547	Droxidopa 屈昔多巴,屈西多巴,SM5688,DOPS,L-DOPS	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Droxidopa (L-DOPS) 是 Droxidopa (w/w80%) 和 Pharmaceutical starch (w/w20%) 的混合物，能透过血脑屏障，可作为神经递质去甲肾上腺素和肾上腺素的原药。
T12352L	Oxidopamine hydrobromide 6-Hydroxydopamine hydrobromide,6-羟基多巴胺氢溴酸盐,6-OHDA hydrobromide	Mitophagy; Dopamine Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Oxidopamine hydrobromide (6-OHDA hydrobromide) 是一种神经递质多巴胺拮抗剂，可选择性地破坏多巴胺能神经元，是一种广泛使用的神经毒素。
T15701	Methyldopa hydrochloride L-(-)-α-Methyldopa hydrochloride,MK-351 hydrochloride	Others	Others
	L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts
T20396	Levadopa Related Compound A 6-Hydroxydopa, L-,L-Hydroxydopa	Others	Others
	Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent and catecholamine-selective neurot
T38221	N,N-Dipropyldopamine (hydrobromide)	Others	Others
	N,N-Dipropyldopamine is a dopamine receptor agonist.1,2,3 It decreases dihydrophenylalanine (DOPA) levels in the limbic forebrain and striatum of reserpinized rats (ED50s = 25 and 20 μmol/kg, respectively), as well as reduces homovanillic acid levels in rat striatum when administered at a dose of 80 μmol/kg.1 N,N-Dipropyldopamine (0.5-16 mg/kg) reduces spontaneous locomotor activity in mice, an effect that can be reversed by the antipsychotic spiroperidol.2,3
T15339	Foscarbidopa Carbidopa 4′-monophosphate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Foscarbidopa is a prodrug of Carbidopa. It acts as a dopamine receptor agonist.
T22779	Fenoldopam	Others	Others
	Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).
T35298	Zelandopam hydrochloride YM 435,YM435,YM-435	Others	Others
	Zelandopam hydrochloride is a biochemical.
T68676	Ciladopa (free base)	Others	Others
	Ciladopa (free base) is a dopamine agonist with a similar chemical structure to dopamine. It was under investigation as an antiparkinsonian agent but was discontinued due to concerns of tumorogenesis in rodents.
T83776	Dopamine D3 Receptor Agonist 13a
	Dopamine D3 受体激动剂13a是一种Dopamine D3 受体激动剂。该化合物选择性地与Dopamine D3 受体结合，相较于Dopamine D1、D2和D4受体(Kis = 0.14、4,600、2.85和756 nM，分别)具有更高的亲和力，并且还能与血清素(5-HT)受体亚型5-HT1A、5-HT2A、5-HT2B和5-HT2C(Kis = 6、54、1.47和252 nM，分别)结合；然而，它是Dopamine D2受体的部分激动剂(EC50 = 2.26 nM，在G蛋白招募分析中)并且作为Dopamine D3受体的拮抗剂(IC50 = 4.62 nM)。在大鼠身上，当剂量为3 mg/kg时，Dopamine D3 受体激动剂13a能减少可卡因自我给药。
T62946	Dopamine D3 receptor antagonist-2	Others	Others
	Dopamine D3 receptor antagonist-2 是一种多巴胺 D3 受体选择性（Ki= 2.16 nM）或多靶点双配体，对中枢神经系统疾病表现出潜在作用。
T60917	Dopamine D4 receptor antagonist-1	Others	Others
	Dopamine D4 receptor antagonist-1 可用于研究精神分裂症。Dopamine D4 receptor antagonist-1 是多巴胺D4受体 (DRD4) 的选择性拮抗剂。Dopamine D4 receptor antagonist-1 对Hd4.2的Ki 值为 9.0 nM。
T60241	N-Methyldopamine hydrochloride	Others	Others
	N-Methyldopamine hydrochloride 是肾上腺素在肾上腺髓质中的前体。N-Methyldopamine hydrochloride 是多巴胺 (DA) 的修饰物，并保留了对 DA1 受体 (DA1 receptor) 的激动剂活性。N-Methyldopamine hydrochloride 具有普遍的表面包覆和利用表面儿茶酚进行二次反应的能力。N-Methyldopamine hydrochloride 可用于心力衰竭的研究。
T64024	Dopamine D3 receptor antagonist-1	Others	Others
	Dopamine D3 receptor antagonist-1 是一种多巴胺 D3受体选择性或多靶点配体，其 Ki 值为 1.58 nM，对中枢神经系统疾病表现出治疗潜能。
T71779	Fenoldopam hydrobromide	Others	Others
	Fenoldopam hydrobromide is a Dopamine D1-receptor agonist that acts as an antihypertensive.
T75537	N-Acetyldopamine dimer-2	Others	Others
	N-Acetyldopamine dimer-2（compound 2）是一种从蝉皮黄色粉末中分离出来的N-acetyldopamine二聚体，具有抗氧化和抗炎作用。它能抑制氧化低密度脂蛋白（LDL）的氧化、ROS的生成、NO的生成以及NF-κB的活性。
T68937	Carbidopa hydrochloride	Others	Others
	Carbidopa hydrochloride is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism of levodopa. This property is significant in that it allows a greater proportion of peripheral levodopa to cross the blood–brain barrier for central nervous system effect.
T70155	Fenoldopam hydrochloride	Others	Others
	Fenoldopam hydrochloride is a selective D1-like dopamine receptor partial agonist. It acts as a vasodilator in vivo and does not readily cross the blood-brain barrier. Fenoldopam HCl is also an α2-adrenoceptor antagonist in vitro.
T68204	Foslevodopa	Others	Others
	Foslevodopa is a dopamine receptor agonist.
T131397	8-Oxopseudopalmatine	Others	Others
	8-Oxopseudopalmatine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131397。
T74081	N-β-alanyldopamine hydrochloride	Others	Others
	N-β-alanyldopamine hydrochloride (NBAD hydrochloride) 是血淋巴中多巴胺的主要衍生物。
T36206	Methyldopate	Others	Others
	Methyldopate is an ethyl ester prodrug form of methyldopa , a dopamine decarboxylase inhibitor that has antihypertensive activity in vitro and in vivo., Formulations containing methyldopate have been used in the treatment of hypertension.
T126370	Dopacetamide	Others	Others
	Dopacetamide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126370，CAS号为 1129-53-9。
T60369	Droxidopa hydrochloride	Others	Others
	Droxidopa (L-DOPS) hydrochloride 是一种有效的、具有口服活性的去甲肾上腺素前体。Droxidopa hydrochloride 可增加站立血压，改善直立性低血压症状并提高站立能力。Droxidopa hydrochloride 具有研究神经源性直立性低血压（nOH）和替代性多动症 (注意缺陷多动障碍) 的潜力[3]。
T37533	DOPAL	Others	Others
	DOPAL is an aldehyde product of the oxidative deamination of dopamine by monoamine oxidase.[1] It can be further oxidized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase (ALDH) and, to a lesser extent reduced to 3,4-dihydroxyphenyl ethanol (DOPET). DOPAL is toxic to neurons.[2],[3] It can also oligomerize and precipitate α-synuclein, an event associated with Parkinson's disease.[2] Mice lacking cytosolic and mitochondrial forms of ALDH display increased levels of DOPAL as wel...
T20133	Methyldopate hydrochloride Aldomet Ester hydrochloride,Aldomet,Methyldopate HCl,Methyldopa ethyl ester hydrochloride	Others	Others
	Methyldopate HCl is an agent of antihypertensive.
T23082	NPEC-caged-dopamine	Others	Others
	Dopamine receptor agonist
T68606	Ciladopa hydrochloride	Others	Others
	Ciladopa hydrochloride is a dopaminergic agonist that may be useful in the treatment of Parkinson's disease.
T62528	Dopamine D3 receptor ligand-1	Others	Others
	Dopamine D 3 receptor ligand 是一种有效的、选择性的、高亲和力的多巴胺 D3受体配体，对 D3 (Ki: 8 nM) 的选择性是 D2 (Ki: 715 nM) 的89倍。
T41192	CNV Dopamine	Others	Others
	CNV Dopamine is a carboxynitroveratryl (CNV)-caged dopamine; releases dopamine upon ultraviolet light stimulation (365 nm). Induces dopaminergic currents upon photolysis in brain slices expressing wild-type or GFP-labeled D2receptors. Displays no decrease in current (rundown) with UV light flash duration of up to 100 ms. Pharmacologically inactive prior to photolysis.
T29213	Zelandopam free base YM-435,YM435,MYD-37,MYD37,Zelandopam	Others	Others
	Zelandopam is a dopamine D1 agonist. Zelandopam is a potent stimulant of pancreatic exocrine secretion by acting on DA D1 receptors of the pancreas in dogs. Intravenous administration of Zelandopam produces renal vasodilating and diuretic/natriuretic effe
T31565	Dopan NSC44629,NSC-44629,NSC 44629	Others	Others
	Dopan is a biochemical.
T69105	Methyldopa anhydrous	Others	Others
	Methyldopa anhydrous is a Central alpha-2 Adrenergic Agonist. The mechanism of action of methyldopa anhydrous is as an Adrenergic alpha2-Agonist.

化合物

6-Hydroxy-DOPA

Cat.No: T26396

Synonym: 6-羟基-DL-多巴,6-Hydroxy-DL-DOPA

Target: DNA/RNA Synthesis

Cat.No: T31570

Synonym: DPBX L-Dopa

Target: Others

Cat.No: T37605

Target: Others

Cat.No: T23275

Target: Others

Etilevodopa hydrochloride

Cat.No: T24047

Synonym: Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester

Target: Others, Dopamine Receptor, Drug Metabolite

3-O-methyl-L-DOPA (hydrate)

Cat.No: T36122

Target: Others

Fluorodopa F 18

Cat.No: T31823

Synonym: Fluorodopa (18F),6-(18F)Fluoro-L-DOPA,F-DOPA,L-6-(18F)Fluoro-DOPA,6-(18F)Fluorodopamine

Target: Others

Cat.No: T20700

Target: Others

[18F]-Labeled L-dopa precursor

Cat.No: T74180

Target: Others

Carbidopa monohydrate

Cat.No: T2148

Synonym: Carbidopa Hydrate,S(-)-Carbidopa,卡比多巴水合物

Target: Decarboxylase, Aryl Hydrocarbon Receptor

Methyldopa hydrate

Cat.No: T5954

Synonym: L-甲基多巴,Alpha-Methyldopa Sesquihydrate,L-(-)-α-Methyldopa hydrate,MK-351 hydrate,Methyldopa Sesquihydrate

Target: Dopamine Receptor, Adrenergic Receptor

Dopamine D2 receptor agonist-2

Cat.No: T60075

Synonym: Dopamine D2 Receptor

Target: Dopamine Receptor

Oxidopamine hydrochloride

Cat.No: T12352

Synonym: 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride,6-羟基多巴胺盐酸盐

Target: Mitophagy, Dopamine Receptor, Autophagy

Dopamine D2 receptor antagonist-1

Cat.No: T11077

Target: Others

Fenoldopam mesylate

Cat.No: T6835

Synonym: Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐

Target: Dopamine Receptor

5-Hydroxydopamine hydrochloride

Cat.No: T13512

Target: Antifungal

N-Arachidonyldopamine

Cat.No: T62530

Synonym: NADA

Target: Cannabinoid Receptor

Cat.No: T2547

Synonym: 屈昔多巴,屈西多巴,SM5688,DOPS,L-DOPS

Target: Adrenergic Receptor

Oxidopamine hydrobromide

Cat.No: T12352L

Synonym: 6-Hydroxydopamine hydrobromide,6-羟基多巴胺氢溴酸盐,6-OHDA hydrobromide

Target: Mitophagy, Dopamine Receptor, Autophagy

Methyldopa hydrochloride

Cat.No: T15701

Synonym: L-(-)-α-Methyldopa hydrochloride,MK-351 hydrochloride

Target: Others

Levadopa Related Compound A

Cat.No: T20396

Synonym: 6-Hydroxydopa, L-,L-Hydroxydopa

Target: Others

N,N-Dipropyldopamine (hydrobromide)

Cat.No: T38221

Target: Others

Cat.No: T15339

Synonym: Carbidopa 4′-monophosphate

Target: Dopamine Receptor

Cat.No: T22779

Target: Others

Zelandopam hydrochloride

Cat.No: T35298

Synonym: YM 435,YM435,YM-435

Target: Others

Ciladopa (free base)

Cat.No: T68676

Target: Others

Dopamine D3 Receptor Agonist 13a

Cat.No: T83776

Dopamine D3 receptor antagonist-2

Cat.No: T62946

Target: Others

Dopamine D4 receptor antagonist-1

Cat.No: T60917

Target: Others

N-Methyldopamine hydrochloride

Cat.No: T60241

Target: Others

Dopamine D3 receptor antagonist-1

Cat.No: T64024

Target: Others

Fenoldopam hydrobromide

Cat.No: T71779

Target: Others

N-Acetyldopamine dimer-2

Cat.No: T75537

Target: Others

Carbidopa hydrochloride

Cat.No: T68937

Target: Others

Fenoldopam hydrochloride

Cat.No: T70155

Target: Others

Cat.No: T68204

Target: Others

8-Oxopseudopalmatine

Cat.No: T131397

Target: Others

N-β-alanyldopamine hydrochloride

Cat.No: T74081

Target: Others

Cat.No: T36206

Target: Others

Cat.No: T126370

Target: Others

Droxidopa hydrochloride

Cat.No: T60369

Target: Others

Cat.No: T37533

Target: Others

Methyldopate hydrochloride

Cat.No: T20133

Synonym: Aldomet Ester hydrochloride,Aldomet,Methyldopate HCl,Methyldopa ethyl ester hydrochloride

Target: Others

NPEC-caged-dopamine

Cat.No: T23082

Target: Others

Ciladopa hydrochloride

Cat.No: T68606

Target: Others

Dopamine D3 receptor ligand-1

Cat.No: T62528

Target: Others

Cat.No: T41192

Target: Others

Zelandopam free base

Cat.No: T29213

Synonym: YM-435,YM435,MYD-37,MYD37,Zelandopam

Target: Others

Cat.No: T31565

Synonym: NSC44629,NSC-44629,NSC 44629

Target: Others

Methyldopa anhydrous

Cat.No: T69105

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T15138	DL-Dopa	Endogenous Metabolite	Metabolism
	DL-Dopa 是一种苯丙氨酸 β-羟基化衍生物。
T0848	L-DOPA 左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine	Dopamine Receptor; Endogenous Metabolite	GPCR/G Protein; Metabolism; Neuroscience
	L-DOPA (Levodopa) 是的神经递质多巴胺的代谢前体，具有口服活性。Levodopa 能够透过血脑屏障，并在大脑中转化为多巴胺。Levodopa 具有抗痛觉过敏作用。Levodopa 还具有帕金森氏病的研究潜力。
T26288	Clovamide trans-Clovamide,N-trans-Caffeoy-L-dopa	Apoptosis; Influenza Virus; ROS; Antibacterial	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	Clovamide (trans-Clovamide) 是一种天然存在的咖啡酰结合物，具有抗菌、抗炎、抗氧化和神经保护作用。它是一种极好的活性氧和氧自由基清除剂。
T15255	Etilevodopa Levodopa ethyl ester,L-DOPA ethyl ester	Others	Others
	Etilevodopa is an ethyl-ester prodrug of Levodopa which is used for the treatment of Parkinson's disease (PD). It is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Levodopa is the direct precursor of dop
T6795	Carbidopa 卡比多巴,(S)-(-)-Carbidopa,Lodosyn	Decarboxylase; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism; Others
	Carbidopa (Lodosyn) 是一种选择性芳香烃受体(AhR)调节剂，是外周型脱羧酶抑制剂，抑制胰腺癌细胞和肿瘤生长，可用于帕金森病的研究。
T1644	Dopamine hydrochloride 盐酸多巴胺,Dopamine HCl,ASL279	Ferroptosis; Dopamine Receptor; 5-HT Receptor; Endogenous Metabolite	Apoptosis; GPCR/G Protein; Metabolism; Neuroscience
	Dopamine hydrochloride (ASL279) 是在脑黑质、脑腹侧被盖区和下丘脑中产生的一种天然儿茶酚胺，由二羟基苯丙氨酸脱羧形成，是去甲肾上腺素和肾上腺素的前体。它通过 D2 多巴胺受体来诱导 VEGFR2 的内吞作用，有促进血管生成活性。
T0505	Methyldopa L-(-)-α-Methyldopa,MK-351,甲基多巴	Dopamine Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	L-(-)-α-Methyldopa (MK-351) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是 α-肾上腺素能激动剂，对 α2- adrenergic receptors 有选择性。
T73775	Dopamine 3-O-sulfate	Others	Others
	Dopamine 3-O-sulfate，一种主要存在于血浆中的化合物，可作为芳香族氨基酸脱羧酶(AADC)缺乏症的生物标志物。
T40158	N-acetyldopamine NADA,N-乙酰多巴胺	Others	Others
	N-acetyldopamine (NADA) is a catecholamine utilized by insects as a precursor for sclerotization, a process that strengthens their cuticle.
TN6009	Pseudopalmatine
	Pseudopalmatine exhibits antiplasmodial activity. It also shows anti-acetylcholinesterase (AChE) activity, with IC50 values of 1.8uM.
T81710	N-Acetyldopamine dimer-3	Others	Others
	N-Acetyldopamine dimer-3 (compound 11)为Aspongopus chinensis中检出的天然化合物。
TN7518	Dopastin NSC 252927	Others	Others
	Dopamine β-hydroxylase inhibitor is a potent compound.
T3737	3-(2,4-Dihydroxyphenyl)propanoic acid 3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid	Tyrosinase	Proteases/Proteasome
	3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) 是竞争性酪氨酸酶 (tyrosinase) 抑制剂，可抑制 L-Tyrosine 和 DL-DOPA，IC50和 Ki 分别为 3.02 μM 和 11.5 μM。
T4S1962	beta-Asarone β-细辛脑,(Z)-1,2,4-三甲氧基-5-丙烯基苯;顺式细辛脑,Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin	NF-κB; JNK	MAPK; NF-κB
	beta-Asarone (Cis-Isoelemicin) 是一种石菖蒲中的主要成分，具有免疫抑制、促进安定、中枢神经系统抑制、降温等功能。它可透过血脑屏障，能够预防帕金森病。
TN1314	6-Hydroxykaempferol	Tyrosinase	Proteases/Proteasome
	6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
TMA2419	Catalponol	cAMP	GPCR/G Protein
	Catalponol can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the increased levels of cyclic AMP.
TN7350	Gynosaponin TN2	Others	Others
	Gynosaponin TN-2, demonstrating anti-Parkinsonian activity, mitigates L-DOPA (100 and 200 μM)-induced apoptotic cell death in pheochromocytoma 12 cells through the modulation of extracellular signal-regulated protein kinases 1 and 2 activation.
T75563	Vanicoside E	Others	Others
	Vanicoside E 是一种抗氧化和抗癌剂。Vanicoside E 抑制L-Tyrosine 和L-DOPA，IC50为 45.23 μM 和 189.96 μM。
TMA0003	Trans-caffeic acid	cAMP; Tyrosinase	GPCR/G Protein; Proteases/Proteasome
	Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and TRP-1 down-regulation, resulting in the suppression of tyrosinase activity, DOPA oxidase activity and melanin synthesis.
TN3607	Catalpalactone	cAMP	GPCR/G Protein
	Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC50 values of 9.80 microM. Catalpalactone can inhibit dopamine biosynthesis by

天然产物

Cat.No: T15138

Target: Endogenous Metabolite

Cat.No: T0848

Synonym: 左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine

Target: Dopamine Receptor, Endogenous Metabolite

Cat.No: T26288

Synonym: trans-Clovamide,N-trans-Caffeoy-L-dopa

Target: Apoptosis, Influenza Virus, ROS, Antibacterial

Cat.No: T15255

Synonym: Levodopa ethyl ester,L-DOPA ethyl ester

Target: Others

Cat.No: T6795

Synonym: 卡比多巴,(S)-(-)-Carbidopa,Lodosyn

Target: Decarboxylase, Aryl Hydrocarbon Receptor

Dopamine hydrochloride

Cat.No: T1644

Synonym: 盐酸多巴胺,Dopamine HCl,ASL279

Target: Ferroptosis, Dopamine Receptor, 5-HT Receptor, Endogenous Metabolite

Cat.No: T0505

Synonym: L-(-)-α-Methyldopa,MK-351,甲基多巴

Target: Dopamine Receptor, Adrenergic Receptor

Dopamine 3-O-sulfate

Cat.No: T73775

Target: Others

N-acetyldopamine

Cat.No: T40158

Synonym: NADA,N-乙酰多巴胺

Target: Others

Pseudopalmatine

Cat.No: TN6009

N-Acetyldopamine dimer-3

Cat.No: T81710

Target: Others

Cat.No: TN7518

Synonym: NSC 252927

Target: Others

3-(2,4-Dihydroxyphenyl)propanoic acid

Cat.No: T3737

Synonym: 3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid

Target: Tyrosinase

Cat.No: T4S1962

Synonym: β-细辛脑,(Z)-1,2,4-三甲氧基-5-丙烯基苯;顺式细辛脑,Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin

Target: NF-κB, JNK

6-Hydroxykaempferol

Cat.No: TN1314

Target: Tyrosinase

Cat.No: TMA2419

Target: cAMP

Gynosaponin TN2

Cat.No: TN7350

Target: Others

Cat.No: T75563

Target: Others

Trans-caffeic acid

Cat.No: TMA0003

Target: cAMP, Tyrosinase

Cat.No: TN3607

Target: cAMP

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02472	DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His) Aadc,dopa decarboxylase (aromatic L-amino acid deca...	Mouse	Baculovirus Insect Cells
	DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55.2 kDa and the accession number is O88533.
TMPY-01060	DOPA Decarboxylase/DDC Protein, Human, Recombinant (His) dopa decarboxylase (aromatic L-amino acid decarboxy...	Human	Baculovirus Insect Cells
	DOPA Decarboxylase/DDC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 55 kDa and the accession number is Q53Y41.
TMPH-03159	DODA Protein, Portulaca grandiflora, Recombinant (His & Myc & SUMO) DOPA 4,5-dioxygenase,DODA	Portulaca grandiflora	E. coli
	Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. DODA Protein, Portulaca grandiflora, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 49.9 kDa and the accession number is Q7XA48.
TMPH-00047	DODA Protein, Amanita muscaria, Recombinant (His & Myc) DOPA 4,5-dioxygenase,DODA	Amanita muscaria	E. coli
	Extradiol dioxygenase that opens up the cyclic ring of DOPA between carbons 4 and 5 thus producing an unstable seco-DOPA that rearranges non-enzymatically to betalamic acid. Can also catalyze the formation of muscaflavin (a pigment found in the hygrocybe mushrooms family and of some amanita species only) by a 2,3-extradiol cleavage of DOPA. DODA Protein, Amanita muscaria, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight...
TMPH-03377	SULT1B1 Protein, Rat, Recombinant (His & Myc & SUMO) DOPA/tyrosine sulfotransferase,Sult1b1,Sulfotransfe...	Rat	E. coli
	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3). SULT1B1 Protein, Rat, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 54.8 kDa and the accession number is P...
TMPY-03852	Dopamine beta-Hydroxylase Protein, Human, Recombinant (His) dopamine β-hydroxylase (dopamine β-monooxy...	Human	HEK293 Cells
	DBH is a 29 kDa copper-containing oxygenase. It can be detected in noradrenergic nerve terminals of the central and peripheral nervous systems, and is also expressed in chromaffin cells of the adrenal medulla. DBH contains our identical subunits, and its activity requires ascorbate as a cofactor. It functions in in the synthesis of small-molecule neurotransmitters that is membrane-bound, making norepinephrine the only transmitter synthesized inside vesicles. DBH has been shown to be associated ...
TMPH-02269	Tyrosinase/TYR Protein, Human, Recombinant (His) Tyrosinase,SK29-AB,Monophenol monooxygenase,Tumor rejection ...	Human	P. pastoris (Yeast)
	This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
TMPH-02270	Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO) SK29-AB,LB24-AB,TYR,Monophenol monooxygenase,Tyrosinase,Tumo...	Human	E. coli
	This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
TMPH-02621	DAO Protein, Mouse, Recombinant (His) DAMOX,Dao1,DAO,DAAO,D-amino-acid oxidase	Mouse	E. coli
	Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system...
TMPH-03276	DAO Protein, Rat, Recombinant (His & Myc) D-amino-acid oxidase,Dao1,DAMOX,DAO,DAAO	Rat	E. coli
	Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression sy...
TMPJ-00853	DAO Protein, Human, Recombinant (His) D-Amino-Acid Oxidase,DAMOX,DAAO,DAO	Human	E. coli
	D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also a...

重组蛋白

DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02472

Species: Mouse

Expression System: Baculovirus Insect Cells

DOPA Decarboxylase/DDC Protein, Human, Recombinant (His)

Cat.No: TMPY-01060

Species: Human

Expression System: Baculovirus Insect Cells

DODA Protein, Portulaca grandiflora, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03159

Species: Portulaca grandiflora

Expression System: E. coli

DODA Protein, Amanita muscaria, Recombinant (His & Myc)

Cat.No: TMPH-00047

Species: Amanita muscaria

Expression System: E. coli

SULT1B1 Protein, Rat, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03377

Species: Rat

Expression System: E. coli

Dopamine beta-Hydroxylase Protein, Human, Recombinant (His)

Cat.No: TMPY-03852

Species: Human

Expression System: HEK293 Cells

Tyrosinase/TYR Protein, Human, Recombinant (His)

Cat.No: TMPH-02269

Species: Human

Expression System: P. pastoris (Yeast)

Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02270

Species: Human

Expression System: E. coli

DAO Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02621

Species: Mouse

Expression System: E. coli

DAO Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03276

Species: Rat

Expression System: E. coli

DAO Protein, Human, Recombinant (His)

Cat.No: TMPJ-00853

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T34589	SD-1077 d3-L-DOPA,deuldopa,deuterated levodopa,SD1077
	SD-1077, also known as d3-L-DOPA, is a deuterium containing levodopa. SD-1077 has been shown in preclinical models to improve the half-life of dopamine in the brain resulting in a prolonged treatment effect.
TMIJ-0312	L-Dopa-2,5,6-d3
	L-Dopa-2,5,6-d3 是 L-Dopa 的氘代化合物。L-Dopa 的 CAS 号为 59-92-7。Levodopa 是的神经递质多巴胺的代谢前体，具有口服活性。Levodopa 能够透过血脑屏障，并在大脑中转化为多巴胺。Levodopa具有抗痛觉过敏作用。Levodopa还具有帕金森氏病的研究潜力。
TMIH-0049	3-O-Methyldopa-d3
	3-O-Methyldopa-d3 是 3-O-Methyldopa 的氘代化合物。3-O-Methyldopa 的 CAS 号为 300-48-1。
TMIH-0340	Methyldopa-d3
	Methyldopa-d3 是 Methyldopa 的氘代化合物。Methyldopa 的 CAS 号为 6014-30-8。
TMIH-0047	3-Methoxy Dopamine-d4 Hydrochloride
	3-Methoxy Dopamine-d4 Hydrochloride 是 3-Methoxy Dopamine Hydrochloride 的氘代化合物。
TMID-0114	3-Methoxy-L-tyrosine-d3 monohydrate
	3-Methoxy-L-tyrosine-d3 monohydrate 是 3-Methoxy-L-tyrosine monohydrate 的氘代化合物。3-Methoxy-L-tyrosine monohydrate 的 CAS 号为 200630-46-2。
TMIJ-0082	Benserazide-d3 HCl
	Benserazide-d3 HCl 是 Benserazide HCl 的氘代化合物。Benserazide HCl 的 CAS 号为 14919-77-8。Benserazide hydrochloride 是一种芳香族 L-氨基酸脱羧酶（AADC）的抑制剂，常用于帕金森病。

同位素标记化合物

Cat.No: T34589

Synonym: d3-L-DOPA,deuldopa,deuterated levodopa,SD1077

L-Dopa-2,5,6-d3

Cat.No: TMIJ-0312

3-O-Methyldopa-d3

Cat.No: TMIH-0049

Cat.No: TMIH-0340

3-Methoxy Dopamine-d4 Hydrochloride

Cat.No: TMIH-0047

3-Methoxy-L-tyrosine-d3 monohydrate

Cat.No: TMID-0114

Benserazide-d3 HCl

Cat.No: TMIJ-0082

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼